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Critical Care
Published in: Critical Care 1/2020

01-12-2020 | Stroke | Letter

Mechanical ventilation and neurocritical patients: is there a role for anti-neuroinflammatory therapies?

Authors: Giovanni Giordano, Francesco Pugliese, Federico Bilotta

Published in: Critical Care | Issue 1/2020

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Excerpt

Dear Editor, …
Literature
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Robba C, Bonatti G, Battaglini D, Rocco PRM, Pelosi P. Mechanical ventilation in patients with acute ischaemic stroke: from pathophysiology to clinical practice. Crit Care. 2019;23(1):388.CrossRef
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Kamuf J, Garcia-Bardon A, Ziebart A, et al. Lung injury does not aggravate mechanical ventilation-induced early cerebral inflammation or apoptosis in an animal model. PLoS One. 2018;13(8):e0202131.CrossRef
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Bilotta F, Giordano G, Sergi PG, Pugliese F. Harmful effects of mechanical ventilation on neurocognitive functions. Crit Care. 2019;23(1):273.CrossRef
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Hegeman MA, Hennus MP, Heijnen CJ, Specht PA, Lachmann B, Jansen NJ, et al. Ventilator-induced endothelial activation and inflammation in the lung and distal organs. Crit Care. 2009;13:R182.CrossRef
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Klinger RY, Cooter M, Berger M, et al. Effect of intravenous lidocaine on the transcerebral inflammatory response during cardiac surgery: a randomized-controlled trial. Can J Anaesth. 2016;63(11):1223–32.CrossRef
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Samary CS, Pelosi P, Leme Silva P, Rocco PRM. Immunomodulation after ischemic stroke: potential mechanisms and implications for therapy. Crit Care. 2016;20:391.CrossRef
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Yew WP, Djukic ND, Jayaseelan JSP, Walker FR, Roos KAA, Chataway TK, Muyderman H, Sims NR. Early treatment with minocycline following stroke in rats improves functional recovery and differentially modifies responses of peri-infarct microglia and astrocytes. J Neuroinflammation. 2019;16(1):6.
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González-López A, López-Alonso I, Aguirre A, Amado-Rodríguez L, Batalla-Solís E, Astudillo A, Tomás-Zapico C, Fueyo A, Dos SCC, Talbot K, Albaiceta GM. Mechanical ventilation triggers hippocampal apoptosis by vagal and dopaminergic pathways.Am J Respir Crit Care Med. 2013;188(6):693–702.CrossRef
Metadata
Title
Mechanical ventilation and neurocritical patients: is there a role for anti-neuroinflammatory therapies?
Authors
Giovanni Giordano
Francesco Pugliese
Federico Bilotta
Publication date
01-12-2020
Publisher
BioMed Central
Published in
Critical Care / Issue 1/2020
Electronic ISSN: 1364-8535
DOI
https://doi.org/10.1186/s13054-020-2737-6

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