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Critical Care
Published in: Critical Care 1/2019

Open Access 01-12-2019 | Ultrasound | Research

Ultrasound-based clinical profiles for predicting the risk of intradialytic hypotension in critically ill patients on intermittent dialysis: a prospective observational study

Authors: Rogerio da Hora Passos, Juliana Caldas, Joao Gabriel Rosa Ramos, Erica Batista dos Santos Galvão de Melo, Michel Por Deus Ribeiro, Maria Fernanda Coelho Alves, Paulo Benigno Pena Batista, Octavio Henrique Coelho Messeder, Augusto Manoel de Carvalho de Farias, Etienne Macedo, Jean Jacques Rouby

Published in: Critical Care | Issue 1/2019

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Abstract

Background

Intradialytic hypotension, a complication of intermittent hemodialysis, decreases the efficacy of dialysis and increases long-term mortality. This study was aimed to determine whether different predialysis ultrasound cardiopulmonary profiles could predict intradialytic hypotension.

Methods

This prospective observational single-center study was performed in 248 critically ill patients with acute kidney injury undergoing intermittent hemodialysis. Immediately before hemodialysis, vena cava collapsibility was measured by vena cava ultrasound and pulmonary congestion by lung ultrasound. Factors predicting intradialytic hypotension were identified by multiple logistic regression analysis.

Results

Intradialytic hypotension was observed in 31.9% (n = 79) of the patients, interruption of dialysis because of intradialytic hypotension occurred in 6.8% (n = 31) of the sessions, and overall 28-day mortality was 20.1% (n = 50). Patients were classified in four ultrasound profiles: (A) 108 with B lines > 14 and vena cava collapsibility > 11.5 mm m−2, (B) 38 with B lines < 14 and vena cava collapsibility ≤ 11.5 mm m−2, (C) 36 with B lines > 14 and vena cava collapsibility Di ≤ 11.5 mm m−2, and (D) 66 with B lines < 14 and vena cava collapsibility > 11.5 mm m−2. There was an increased risk of intradialytic hypotension in patients receiving norepinephrine (odds ratios = 15, p = 0.001) and with profiles B (odds ratios = 12, p = 0.001) and C (odds ratios = 17, p = 0.001).

Conclusion

In critically ill patients on intermittent hemodialysis, the absence of hypervolemia as assessed by lung and vena cava ultrasound predisposes to intradialytic hypotension and suggests alternative techniques of hemodialysis to provide better hemodynamic stability.
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Metadata
Title
Ultrasound-based clinical profiles for predicting the risk of intradialytic hypotension in critically ill patients on intermittent dialysis: a prospective observational study
Authors
Rogerio da Hora Passos
Juliana Caldas
Joao Gabriel Rosa Ramos
Erica Batista dos Santos Galvão de Melo
Michel Por Deus Ribeiro
Maria Fernanda Coelho Alves
Paulo Benigno Pena Batista
Octavio Henrique Coelho Messeder
Augusto Manoel de Carvalho de Farias
Etienne Macedo
Jean Jacques Rouby
Publication date
01-12-2019
Publisher
BioMed Central
Published in
Critical Care / Issue 1/2019
Electronic ISSN: 1364-8535
DOI
https://doi.org/10.1186/s13054-019-2668-2

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