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Open Access 01-12-2017 | Commentary

Analysis of the factors affecting the evolution over time of subclinical hypothyroidism in children

Authors: Mariella Valenzise, Tommaso Aversa, Giuseppina Zirilli, Giuseppina Salzano, Domenico Corica, Simona Santucci, Filippo De Luca

Published in: Italian Journal of Pediatrics | Issue 1/2017

Abstract

Aim of this commentary is to report the most recent views about natural history of subclinical hypothyroidism (SH) according to the different etiologies. In children with idiopathic SH the natural evolution is often favourable, with a high percentage of cases reverting to euthyroidism or remaining SH even after a prolonged follow-up. By contrast, the risk of a significant deterioration of thyroid status is distinctly higher in the SH children with Hashimoto’s thyroiditis (HT). This risk is even higher in the cases with both HT-related SH and chromosomal abnormalities, such as Turner or Down’s syndrome.

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Title: Analysis of the factors affecting the evolution over time of subclinical hypothyroidism in children
Authors: Mariella Valenzise
Tommaso Aversa
Giuseppina Zirilli
Giuseppina Salzano
Domenico Corica
Simona Santucci
Filippo De Luca
Publication date: 01-12-2017
Publisher: BioMed Central
Published in: Italian Journal of Pediatrics / Issue 1/2017
Electronic ISSN: 1824-7288
DOI: https://doi.org/10.1186/s13052-016-0322-z

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Analysis of the factors affecting the evolution over time of subclinical hypothyroidism in children

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