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Journal of Cardiothoracic Surgery
Published in: Journal of Cardiothoracic Surgery 1/2019

Open Access 01-12-2019 | Achalasia | Review

The 2 years’ long-term efficacy and safety of peroral endoscopic myotomy for the treatment of achalasia: a systematic review

Authors: Huan Li, Wei Peng, Shu Huang, Yutang Ren, Yan Peng, Qing Li, Jiao Wu, Xiangsheng Fu, Xiaowei Tang

Published in: Journal of Cardiothoracic Surgery | Issue 1/2019

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Abstract

Aim

In this retrospective review, we aimed to investigate the long-term efficacy and safety of POEM with follow-up period over 2 years.

Materials and methods

A systematic review related to POEM for achalasia was conducted. A literature search was performed in Pubmed, Medline, Ovid, Cochrane and EBSCO databases on November 2017. The following postoperative outcomes were extracted: Eckardt score, lower esophageal sphincter pressure, complications and clinical success.

Results

The total number of patients was 373. The mean operative time was 66.7 min and the overall rate of complications was 21.2%. The mean follow-up period was 30.0 months. The overall clinical success rate was 92.9% and the rate of gastroesophageal reflux disease was 10.2%. Rate of mortality after POEM was 0.

Conclusions

Our study demonstrated that POEM is effective and safe for treating achalasia during the long-term followed up over 2 years.
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Metadata
Title
The 2 years’ long-term efficacy and safety of peroral endoscopic myotomy for the treatment of achalasia: a systematic review
Authors
Huan Li
Wei Peng
Shu Huang
Yutang Ren
Yan Peng
Qing Li
Jiao Wu
Xiangsheng Fu
Xiaowei Tang
Publication date
01-12-2019
Publisher
BioMed Central
Keyword
Achalasia
Published in
Journal of Cardiothoracic Surgery / Issue 1/2019
Electronic ISSN: 1749-8090
DOI
https://doi.org/10.1186/s13019-018-0811-9

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