Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress 2023 EHA Congress 2023 ASCO Annual Meeting
Clinical Collections
Advances in Alzheimer’s

Keynote webinar | Spotlight on sleep in brain health

LIVE: Thursday 2nd May 2024, 18:00-19:30 (CEST)

Quality sleep is essential for health. But what happens to our brains when sleep patterns are disturbed? Join our experts to explore the interplay between sleep disruption and neurological diseases, and the questions that you need to be asking your patients to help you prevent the harmful effects of sleep deprivation.
ADVANCED SEARCH
Log in
Top
Journal of Orthopaedic Surgery and Research
Published in: Journal of Orthopaedic Surgery and Research 1/2019

Open Access 01-12-2019 | Anemia | Research article

Blood management in fast-track orthopedic surgery: an evidence-based narrative review

Authors: Federico Pennestrì, Nicola Maffulli, Paolo Sirtori, Paolo Perazzo, Francesco Negrini, Giuseppe Banfi, Giuseppe M Peretti

Published in: Journal of Orthopaedic Surgery and Research | Issue 1/2019

Login to get access

Abstract

Background and purpose

Innovations able to maintain patient safety while reducing the amount of transfusion add value to orthopedic procedures. Opportunities for improvement arise especially in elective procedures, as long as room for planning is available. Although many strategies have been proposed, there is no consensus about the most successful combination. The purpose of this investigation is to identify information to support blood management strategies in fast-track total joint arthroplasty (TJA) pathway, to (i) support clinical decision making according to current evidence and best practices, and (ii) identify critical issues which need further research.

Methods and materials

We identified conventional blood management strategies in elective orthopedic procedures. We performed an electronic search about blood management strategies in fast-track TJA. We designed tables to match every step of the former with the latter. We submitted the findings to clinicians who operate using fast-track surgery protocols in TJA at our research hospital.

Results

Preoperative anemia detection and treatment, blood anticoagulants/aggregants consumption, transfusion trigger, anesthetic technique, local infiltration analgesia, drainage clamping and removals, and postoperative multimodal thromboprophylaxis are the factors which can add best value to a fast-track pathway, since they provide significant room for planning and prediction.

Conclusion

The difference between conventional and fast-track pathways does not lie in the contents of blood management, which are related to surgeons/surgeries, materials used and patients, but in the way these contents are integrated into each other, since elective orthopedic procedures offer significant room for planning. Further studies are needed to identify optimal regimens.
Literature
1.
Jasper LL, Jones CA, Mollins J, Pohar SL, Beaupre LA. Risk factors for revision of total knee arthroplasty: a scoping review. BMC Musculoskeletal Disord. 2016;17:182.CrossRef
2.
Kurtz S, Ong K, Lau E, Mowat F, Halpern M. Projections of primary and revision hip and knee arthroplasty in the United States from 2005 to 2030. J Bone Joint Surg. Am. 2007;89:780–5.PubMed
3.
Ponnusamy KE, Kim TJ, Khanuja HS. Perioperative blood transfusions in orthopaedic surgery. J Bone Joint Surg Am. 2014;96:1836–44.PubMedCrossRef
4.
Kopolovic I, Ostro J, Tsubota H, Lin Y, Cserti-Gazdewich CM, Messner HA, Keir AK, DenHollander N, Dzik WS, Callum J. A systematic review of transfusion-associated graft-versus-host disease. Blood. 2015;126:406–14.PubMedCrossRef
5.
Dwyre D, Fernando LP, Holland PV. Hepatitis B, hepatitis C and HIV transfusion-transmitted infections in the 21st century. Vox Sang. 2011;100:92–8.PubMedCrossRef
6.
Perkins HA, Busch MP. Transfusion-associated infections: 50 years of relentless challenges and remarkable progress. Transfusions. 2010;50:2080–99.CrossRef
7.
Bierbaum BE, Callaghan JJ, Galante JO, Rubash HE, Tooms RE, Welch RB. An analysis of blood management in patients having a total hip or knee arthroplasty. J Bone Join Surg Am. 1999;81:2–10.CrossRef
8.
Moonen AFCM, Neal TD, Pilot P. Peri-operative blood management in elective orthopaedic surgery. A critical review of the literature. Injury. 2006;37(Suppl 5):S11–6.PubMedCrossRef
9.
Song JH, Park JW, Lee YK, Kim IS, Nho JH, Lee KJ, Park KK, Kim Y, Park JH, Han SB. Management of Blood Loss in Hip Arthroplasty: Korean Hip Society Current Consensus. Hip Pelvis. 2017;29:81–90.PubMedPubMedCentralCrossRef
10.
Porter ME, Teisberg EO. Redefining Competition in Health Care. Harv Bus Rev. 2004;82:64–76.PubMed
11.
Kansagra A, Andrzejewski C, Krushell R, Lehman A, Greenbaum J, Visintainer P, McGirr J, Mahoney K, Cloutier D, Ehresman A, Stefan MS. Blood management strategies to reduce transfusions after elective lower-extremity joint arthroplasty surgeries: one tertiary care hospital’s early experience with an alternative payment model—a total joint “Bundle”. Am J Med Qual. 2017;32:668–74.PubMedCrossRef
12.
Kim K, Iorio R. The 5 Clinical Pillars of Value for Total joint arthroplasty in a bundled payment paradigm. J Arthroplasty. 2017;32:1712–6.PubMedCrossRef
13.
Benedetti MG, Sarti D, Bonfiglioli Stagni S, Mariani E. Setting, clinical pathways, fast-track and rehabilitation following knee arthroplasty: a literature review. Open Rehabil J. 2015;8:17–24.CrossRef
14.
Stowers MD, Lemanu DP, Coleman B, Hill AG, Munro JT. Review article: Perioperative care in enhanced recovery for total hip and knee arthroplasty. J Orthop Surg (Hong Kong). 2014;22:383–92.CrossRef
15.
Husted H, Holm G, Jacobsen S. Predictors of length of stay and patient satisfaction after hip and knee replacement surgery: fast-track experience in 712 patients. Acta Orthop. 2008;79:168–73.PubMedCrossRef
16.
Pitter FT, Jørgensen CC, Lindberg-Larsen M, Kehlet H. Lundbeck Foundation Center for fast-track hip and knee replacement collaborative group. Anesth Analg. 2016;122:1807–15.PubMedCrossRef
17.
Lovecchio F, Alvi H, Sahota S, Beal M, Manning D. Is Outpatient arthroplasty as safe as fast-track inpatient arthroplasty? A propensity score matched analysis. J Arthroplasty. 2016;31:197–201.PubMedCrossRef
18.
Tzatzairis T, Vogiatzaki T, Kazakos K, Drosos IG. Perioperative blood management strategies for patients undergoing total knee replacement: Where do we stand now? World J Orthop. 2017;8:441–54.CrossRef
19.
Holt JB, Miller BJ, Callaghan JJ, Clark CR, Willeborg MD, Noiseux NO. Minimizing blood transfusion in total hip and knee arthroplasty: a muldimodal approach. J Arthroplasty. 2016;31:378–82.PubMedCrossRef
20.
Cherian JJ, Kapadia BH, Issa K, Banerjee S, McInerney VK, Harwin SF, Mont MA. Preoperative blood management strategies for total hip arthroplasty. Surg Technol Int. 2013;23:261–6.PubMed
21.
Zhang S, Huang Q, Xu B, Ma J, Cao G, Pei F. Effectiveness and safety of an optimized blood management program in total hip and knee arthroplasty. Medicine (Baltimore). 2018;97:e9429.CrossRef
22.
Venclauskas L, Jenny JY, Kiaersgaard-Andersen P, Jans Ø. ESA VTE guidelines task force. Eur J Anaesthesiol. 2018;35:134–8.PubMed
23.
Kamath AF, Pagnano MW. Blood management for patients undergoing total joint arthroplasty. JBJS Rev. 2013:1.CrossRef
24.
Liumbruno GM, Bennardello F, Lattanzio A, Piccoli P, Rossetti G, Italian Society of Transfusion Medicine and Immunohaematology (SIMTI) Working Party. Recommendations for the transfusion management of patients in the peri-operative period. I. The pre-operative period. Blood Transfus. 2011a;9:19–40.PubMedPubMedCentral
25.
Liumbruno GM, Bennardello F, Lattanzio A, Piccoli P, Rossetti G, Italian Society of Transfusion Medicine and Immunohaematology (SIMTI) Working Party. Recommendations for the transfusion management of patients in the peri-operative period. II. The intra-operative period. Blood Transfus. 2011b;9:189–217.PubMedPubMedCentral
26.
Liumbruno GM, Bennardello F, Lattanzio A, Piccoli P, Rossetti G, Italian Society of Transfusion Medicine and Immunohaematology (SIMTI) Working Party. Recommendations for the transfusion management of patients in the peri-operative period. III. The pre-operative period. Blood Transfus. 2011c;9:320–35.PubMedPubMedCentral
27.
28.
Vaglio S, Prisco D, Biancofiore G, Rafanelli D, Antonioli P, Lisanti M, Andreani L, Basso L, Velati C, Grazzini G, Liumbruno GM. Recommendations for the implementation of a patient blood management programme. Application to elective major orthopaedic surgery in adults. Blood transfus. 2016;14:23–65.PubMedPubMedCentral
29.
Goodnough LT, Maniatis A, Earnshaw P, Benoni G, Beris P, Bisbe E, Fergusson DA, Gombotz H, Habler O, Monk TG, Ozier Y, Slappendel R, Szapalski M. Detection, evaluation, and management of preoperative anaemia in the elective orthopaedic surgical patient: NATA guidelines. Br J Anaesthes. 2011;106:13–22.CrossRef
30.
McLean E, Cogswell E, Egli I, Wojdyla D, de Benoist B. Worldwide prevalence of anaemia, WHO vitamin and Mineral Nutrition Information System, 1993-2005. Public Health Nutr. 2009;12:444–54.PubMedCrossRef
31.
Muňoz M, Gomez-Ramirez S, Kozek-Langener S, Shander A, Richards T, Pavía J, Kehlet H, Acheson AG, Evans C, Raobaikady R, Javidroozi M, Auerbach M. “Fit to fly”: overcoming barriers to preoperative haemoglobin optimization in surgical patients. Br J Anaesth. 2015;115:15–24.PubMedCrossRef
32.
Theusinger OM, Kind SL, Seifert B, Borgeat L, Gerber C, Spahn DR. Patient blood management in orthopaedic surgery: a four-year follow-up of transfusion requirements and blood loss from 2008 to 2011 at the Balgrist University Hospital in Zurich, Switzerland. Blood Transfus. 2014;12:195–203.PubMedPubMedCentral
33.
Rogers BA, Cowie A, Alcock C, Rosson JW. Identification and treatment of anaemia in patients awaiting hip replacement. Ann R Coll Surg Engl. 2008;90:504–7.PubMedPubMedCentralCrossRef
34.
Rosencher N, Poisson D, Albi A, Aperce M, Barré J, Samama CM. Two injections of erythropoietin correct moderate anemia in most patients awaiting orthopedic surgery. Can J Anaesth. 2005;52:160.5.PubMedCrossRef
35.
Husted H, Holm G. Fast track in total hip and knee arthroplasty—experiences from Hvidovre University Hospital, Denmark. Injury. 2006;37:S31–5.PubMedCrossRef
36.
Jans Ø, Jørgensen C, Kehlet H, Johansson PI. Lundbeck Foundation Centre for Fast-track Hip and Knee Replacement Collaborative Group. Transfusion. 2014;54:717–26.PubMedCrossRef
37.
Jans Ø, Bandholm T, Kurbegovic S, Solgaard S, Kjaersgaard-Andersen P, Johansson PI, Kehlet H. Lundbeck Foundation Centre for Fast-Track Hip and Knee Replacement Collaborative Group. Blood Management. 2016;56:917–25.
38.
Guralnik JM, Eisenstaedt RS, Ferrucci L, Klein HG, Woodman RC. Prevalence of anemia in persons 65 years and older in the United States: evidence for a high rate of unexplained anemia. Blood. 2004;104:2263–8.PubMedCrossRef
39.
Guyatt GH, Patterson C, Ali M, Singer J, Levine M, Turpie I, Meyer R. Diagnosis of iron-deficiency anemia in the elderly. Am J Med. 1990;88:205–9.PubMedCrossRef
40.
Kopanidis P, Hardidge A, McNicol L, Tay S, McCall P, Weinberg L. Perioperative blood management programme reduces the use of blood allogenic transfusion in patients undergoing total hip and knee arthroplasty. J Orthop Surg Res. 2016;11:28.PubMedPubMedCentralCrossRef
41.
Beris P, Muńoz M, García-Erce JA, Thomas D, Maniatis A, Van der Linden P. Perioperative anaemia management: consensus statement on the role of intravenous iron. Br J Anaesthesia. 2008:599–604.PubMedCrossRef
42.
Onken JE, Bregman DB, Harrington RA, Morris D, Acs P, Akright B, Barish C, Bhaskar BS, Smith-Nguyen NG, Butcher A, Koch TA, Goodnough LT. A multicenter, randomized, active-controlled study to investigate the efficacy and safety of intravenous ferric carboxymaltose in patients with iron deficiency anemia. Transfusion. 2014;54:306–15.PubMed
43.
44.
Muňoz M, García-Erce JA, Cuenca J, Bisbe E, Naveira E, AWGE (Spanish Amnaemia Working Group). On the role of iron therapy for reducing allogenic blood transfusion in orthopaedic surgery. Blood Transfus. 2012;10:8–22.PubMedPubMedCentral
45.
Jans Ø, Nielsen CS, Khan N, Gromov K, Troelsen A, Husted H. Iron deficiency and preoperative anaemia in patients scheduled for elective hip- and knee arthroplasty—an observational study. Vox Sang. 2018;113:260–7.PubMedCrossRef
46.
Scardino M, Di Matteo B, Martorelli F, Tanzi D, Kon E, D’Amato T. Improved patient blood management and cost saving in hip replacement surgery through the implementation of pre-operative Sucrosomial® iron supplementation: a quality improvement assessment study. Int Orthop. 2019;43:39–46.PubMedCrossRef
47.
Tendera M, Wojakowski W. Role of antiplatelet drugs in the prevention of cardiovascular events. Thromb Res. 2003;110:5–6.CrossRef
48.
Douketis JD, Spyropoulos AC, Spencer FA, Mayr M, Jaffer AK, Eckman MH, Dunn AS, Kunz R. Perioperative management of antithrombotic therapy: antithrombotic therapy and prevention of thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest. 2012;141:e326S–50S.PubMedPubMedCentralCrossRef
49.
Chassot PG, Delabays A, Spahn DR. Perioperative antiplatelet therapy: the case for continuing therapy in patients at risk of myocardial infarction. Br J Anaesthes. 2007;99:316–28.CrossRef
50.
Vandermeulen EP, Van Aken H, Vermylen J. Anticoagulants and spinal-epidural anesthesia. Anesth Analg. 1994;79:1165–77.PubMedCrossRef
51.
Jørgensen CC, Kehlet H, Lundbeck Foundation centre for fast-track hip and knee replacement collaborative group. Time course and reasons for 90-day mortality in fast-track hip and knee arthroplasty. Acta Anaesthesiol Scand. 2017;61:436–44.PubMedCrossRef
52.
Jørgensen CC, Petersen MA, Kehlet H. Lundbeck Foundation Centre for Fast-Track Hip and Knee Replacement Collaborative Group. BMJ Open. 2016;6:e009813.PubMedPubMedCentralCrossRef
53.
Petersen PB, Kehlet H, Jørgensen CC, Lundbeck foundation centre for fast-track hip and knee replacement collaborative group. Safey of in-hospital only thromboprophylaxis after fast-track total hip and knee arthroplasty: a prospective follow-up study in 17.582 Procedures. Thromb Haemost. 2018;118:2152–61.PubMedCrossRef
54.
Gombotz H, Rehak PH, Shander A, Hofmann A. Blood use in elective surgery: the Austrian benchmark study. Transfusion. 2007;47:1468–80.PubMedCrossRef
55.
Young SW, Marsh DJ, Akhavani MA, Walker CG, Skinner JA. Attitudes to blood transfusion post arthroplasty surgery in the United Kingdom: a national survey. Int Orthop. 2008;32:325–9.PubMedCrossRef
56.
Cobain TJ, Vamvakas EC, Wells A, Titlestad K. A survey of the demographics of blood use. Transfus Med. 2007;17:1–15.PubMedCrossRef
57.
Barr PJ, Donnelly M, Cardwell C, Alam SS, Morris K, Parker M, Bailie KE. Drivers of transfusion decision making and quality of the evidence in orthopedic surgery: a systematic review of the literature. Transfus Med Rev. 2011;25:304–16.PubMedCrossRef
58.
Slappendel R, Dirksen R, Weber EW, van der Schaaf DB. An algorithm to reduce allogenic red blood cell transfusions for major orthopedic surgery. Acta Orthop Scand. 2003;74:569–75.PubMedCrossRef
59.
Ballantyne A, Walmsley P, Brenkel I. Reduction of blood transfusion rates in unilateral total knee arthroplasty by the introduction of a simple blood transfusion protocol. Knee. 2003;10:379–84.PubMedCrossRef
60.
61.
Husted H, Lunn TH, Troelsen A, Gaarn-Larsen L, Kristensen BB, Kehlet H. Why still in hospital after fast-track hip and knee arthroplasty? Acta Orthop. 2011;82:679–84.PubMedPubMedCentralCrossRef
62.
Jans Ø, Kehlet J, Johansson PI. Blood transfusion in major orthopaedic surgery. Ugeskr Laeger. 2011;173:815–7.PubMed
63.
Weber EW, Slappendel R, Hemon Y, Mähler S, Dalén T, Rouwet E, van Os J, Vosmaer A, van der Ark P. Effects of eopoetin alfa on blood transfusions and postoperative recovery in orthopaedic surgery: the European Epoetin Alfa Surgery Trial (EEST). Eur J Anaesthesiol. 2005;22:249–57.PubMedCrossRef
64.
Goodnough LT, Monk TG. Erythropoietin therapy in the perioperative setting. Clin Orthop Related Res. 1998;357:82–8.CrossRef
65.
Faris PM, Ritter MA. Epoetin alfa. A bloodless approach for the treatment of perioperative anemia. Clin Orthop Relat Res. 1998;357:60–7.CrossRef
66.
De Andrade JR, Jove M, Landon G, Frei D, Guilfoyle M, Young DC. Baseline hemoglobin as a predictor of risk of transfusion and response to Epoetin alfa in orthopedic surgery patients. Am J Orthop (Belle Mead NJ). 1996;25:533–42.
67.
Slappendel R, Weber EW, Hémon YJ, Mähler S, Dalén T, Rouwet EF, van Os JJ, Vosmaer A, van der Ark PD. Patients with and without rheumatoid arthritis benefit equally from preoperative epoetin-alpha treatment. Acta Orthop. 2006;77:677–83.PubMedCrossRef
68.
Keating EM, Callaghan JJ, Ranawat AS, Bhirangi K, Ranawat CS. A randomized, parallel-group, open-label trial of recombinant human erythropoietin vs preoperative autologous donation in primary total joint arthroplasty: effect of postoperative vigor and handgrip strength. J Arthroplasty. 2007;22:235–3.CrossRef
69.
Deutsch A, Spaulding J, Marcus RE. Preoperative epoetin alfa vs autologous blood donation in primary total knee arthroplasty. J Arthroplasty. 2006;21:628–35.PubMedCrossRef
70.
Rosencher N, Poisson D, Albi A, Aperce M, Barré J, Samama CM. Two injections of eryhtopoietin correct moderate anemia in most patients awaiting orthopedic surgery. Can J Anaesth. 2005;52:160–5.PubMedCrossRef
71.
Bedair H, Yang J, Dwyer MK, McCarthy JC. Preoperative erythropoietin alpha reduces postoperative transfusions in THA and TKA but may not be cost-effective. Clin Orthop Relat Res. 2015;473:590–6.PubMedCrossRef
72.
Vaislic CD, Dalibon N, Ponzio O, Ba M, Jugan E, Lagneau F, Abbas P, Olliver Y, Gaillard D, Baget F, Sportiche M, Chedid A, Chaoul G, Maribas P, Dupuy C, Robine B, Kasanin N, Michon H, Ruat JM, Habis M, Bouharaoua T. Outcomes in cardiac surgery in 500 consecutive Jehovah’s Witness patients: 21 year experience. J Cardiothorac Surg. 2012;7:95.PubMedPubMedCentralCrossRef
73.
Alshryda S, Sukeik M, Sarda P, Blenkinsopp J, Haddad FS, Mason JM. A systematic review and meta-analysis of the topical administration of tranexamic acid in total hip and knee replacement. Bone Joint J. 2014;96-B:1005–15.PubMedCrossRef
74.
Raveendran R, Wong J. Tranexamic acid: more evidence for its use in joint replacement surgery. Transfusion. 2014;54:2–3.PubMedCrossRef
75.
76.
Goldman M, Rémy-Prince S, Trépanier A, Décary F. Autologous donation error rates in Canada. Transfusion. 1997;37:523–7.PubMedCrossRef
77.
Tretiak R, Laupacis A, Rivière M, McKerracher K, Souetre E. Cost of allogenic and autologous blood transfusion in Canada. Canadian Cost of Transfusion Study Group. CMAJ. 1996;154:1501–8.PubMedPubMedCentral
78.
Etchason J, Petz L, Keeler E, Calhoun L, Kleinman S, Snider C, Fink A, Brook R. The cost effectiveness of preoperative autologous blood donations. N Engl J Med. 1995;332:719–24.PubMedCrossRef
79.
Birkmeyer JD, Goodnough LT, AuBuchon JP, Noordsij PG, Littenberg B. The cost-effectiveness of preoperative autologous blood donation for total hip and knee replacement. Transfusion. 1993;33:544–51.PubMedCrossRef
80.
Kozek-Langenecker SA, Afshari A, Albaladejo P, Santullano CA, De Robertis E, Filipescu DC, Fries D, Görlinger K, Haas T, Imberger G, Jacob M, Lancé M, Llau J, Mallett SS, Rahe-Meyer N, Samama CM, Smith A, Solomon C, Van der Linden P, Wikkelsø AJ, Wouters P, Wyffels P. Management of severe perioperative bleeding: guidelines from the European Society of Anaesthesiology. Eur J Anaesthesiol. 2013;30:270–382.PubMedCrossRef
81.
Confalonieri N, Manzotti A, Montironi F, Pullen C. Tissue sparing surgery in knee reconstruction: unicompartmental (UKA), patellofemoral (PFA), UKA + PFA, bi-unicompartmental (Bi-UKA) arthroplasties. J Orthop Traumatol. 2008;9:171–7.PubMedPubMedCentralCrossRef
82.
Regis D, Residori A, Rossi N, Bartolozzi P. Tissue-sparing surgery in total hip arthroplasty: sensible approaches and tested evidence. J Orthopaed Traumatol. 2007;8:199–201.CrossRef
83.
Huang HT, Su JY, Chang JK, Chen CH, Wang GJ. The early clinical outcomes of minimally invasive quadriceps-sparing total knee arthroplasty: report of a 2-year follow-up. J Arthroplasty. 2007;22:1007–12.PubMedCrossRef
84.
Matta JM, Shahrdar C, Ferguson T. Single-incision anterior approach for total hip arthroplasty on an orthopaedic table. Clin Orthop Related Res. 2005;441:115–24.CrossRef
85.
Light TR, Keggi KJ. Anterior approach to hip arthroplasty. Clin Orthop Related Res. 1980;152:255–60.
86.
Chang CW, Wu PT, Yang CY. Blood loss after minimally invasive total knee arthroplasty: effects of imageless navigation. Kaohsiung J Med Sci. 2010;26:237–43.PubMedCrossRef
87.
Lloyd JM, Wainwright T, Middleton RG. What is the role of minimally invasive surgery in a fast track hip and knee replacement? Ann R Coll Surg Engl. 2012;94:148–51.PubMedPubMedCentralCrossRef
88.
Delanois RE, Gwam C, Mistry JB, Khlopas A, Chughtai M, Ramkumar P, Piuzzi N, Berger R, Bonutti PM, Malkani AL, Mont MA. Does Length of Stay Influence How Patients Rate Their Hospitalization After Total Hip Arthroplasty? Surg Technol Int. 2017;30:393–8.PubMed
89.
Ejaz A, Laursen AC, Kappel A, Laursen MB, Jakobsen T, Rasmussen S, Nielsen PT. Faster recovery without the use of a tourniquet in total knee arthroplasty. Acta Orthop. 2014;85:422–6.PubMedPubMedCentralCrossRef
90.
Tai TW, Lin CJ, Jou IM, Chang CW, Lai KA, Yang CY. Tourniquet use in total knee arthroplasty: a meta-analysis. Knee Surg Sport Traumatol Arthrosc. 2011;19:1121–30.CrossRef
91.
Harsten A, Bandholm T, Kehlet H, Toksvig-Larsen S. Tourniquet versus no tourniquet on knee-extension strength early after fast-track total knee arthroplasty; a randomized controlled trial. Knee. 2015;22:126–30.PubMedCrossRef
92.
Concina C, Crucil M, Fabbro S, Gherlinzoni F. Do tourniquet and drainage influence fast track in total knee arthroplasty? Our results in 151 cases. Acta Biomed. 2019;90(1-S):123–9.PubMed
93.
Rantasalo MT, Palanne R, Juutilainen K, Kairaluoma P, Linko R, Reponen E, Helkamaa T, Vakkuri A, Olkkola KT, Madanat R, Skants NKA. Randomised controlled study comparing general and spinal anaesthesia with and without a tourniquet on the outcomes of total knee arthroplasty: study protocol. BMJ Open. 2018;8:e025546.PubMedPubMedCentralCrossRef
94.
Turnbull ZA, Sastow D, Giambrone GP, Tedore T. Anesthesia for the patient undergoing total knee replacement: current status and future prospects. Local Reg Anesth. 2017;10:1–7.PubMedPubMedCentralCrossRef
95.
Macfarlane AJR, Prasad AG, Chan VWS, Brull R. Does regional anesthesia improve outcome after total knee arthroplasty? A systematic review. Br J Anaesth. 2009;103:335–45.PubMedCrossRef
96.
Hu S, Zhang ZY, Hua YQ, Li J, Cai ZD. A comparison of regional and general anaesthesia for total replacement of the hip or knee: a meta-analysis. J Bone Joint Surg Br. 2009;7:935–42.CrossRef
97.
Pugely AJ, Martin CT, Gao Y, Mendoza-Lattes S, Callaghan JJ. Differences in short-term complications between spinal and general anesthesia for primary total knee arthroplasty. J Bone Joint Surg Am. 2013;95:193–9.PubMedCrossRef
98.
Macfarlane AJR, Prasad AG, Chan VWS, Brull R. Does regional anesthesia improve outcome after total knee arthroplasty? Clinic Orthop Related Res. 2009;467:2379–40.CrossRef
99.
Haughom BD, Schairer WW, Nwachukwu BU, Hellman MD, Levine BR. Does neuraxial anesthesia decrease transfusion rates following total hip arthroplasty? J Arthroplasty. 2015;30:116–20.PubMedCrossRef
100.
Rashig S, Finegan BA. The effect of spinal anesthesia on blood transfusion rate in total joint arthroplasty. Can J Surg. 2006;49:391–6.
101.
Harsten A, Kehlet H, Toksvig-Larsen S. Recovery after total intravenous general anaesthesia or spinal anaesthesia for total knee arthroplasty: a randomized trial. Br J Anaesth. 2013;111:391–9.PubMedCrossRef
102.
Sharrock NE, Mineo R, Urquhart B, Salvati EA. The effect of two level of hypotension on intraoperative blood loss during total hip arthroplasty performed under lumbar epidural anesthesia. Anesth Analg. 1993;76:580–4.PubMed
103.
Danninger T, Stundner O, Ma Y, Bae JJ, Memtsoudis SG. The impact of hypothensive epidural anaesthesia on distal and proximal tissue perfusion in patients undergoing total hip arthroplasty. J Anesth Clin Res. 2013;4:366.PubMedPubMedCentralCrossRef
104.
Kiss H, Raffl M, Neumann D, Hutter J, Dorn U. Epinephrine-augmented hypothensive epidural anesthesia replaces tourniquet use in total knee replacement. Clin Orthop Relat Res. 2005;436:184–9.CrossRef
105.
Juelsgaard P, Larsen UT, Sørensen JV, Madsen F, Søballe K. Hypotensive epidural anesthesia in total knee replacement without tourniquet: reduced blood loss and transfusion. Reg Anesth Pain Med. 2001;26:105–10.PubMed
106.
Lerman DM, Rapp TB. Minimizing blood loss in orthopaedic surgery the role of antifibrinolytics. Bull Hosp Jt Dis (2013). 2015;73:83–9.3.
107.
108.
109.
Sepah YJ, Umer M, Ahmad T, Nasim F, Chaudhry MU, Umar M. Use of tranexamic acid is a cost effective method in preventing blood loss during and after total knee replacement. J Orthop Surg Res. 2011;6:22.PubMedPubMedCentralCrossRef
110.
Martin K, Wiesner G, Breuer T, Lange R, Tassani P. The risks of aprotinin and tranexamic acid in cardiac surgery: a one-year follow-up of 1188 consecutive patients. Anesth Analg. 2008;107:1783–90.PubMedCrossRef
111.
Fergusson DA, Hébert PC, Mazer CD, Fremes S, Mac Adams C, Murkin JM, Teoh K, Duke PC, Arellano R, Blajchman MA, Bussières JS, Coté D, Karski J, Martineau R, Robblee JA, Rodger M, Wells G, Clinch J, Pretorius R, BART Investigators. A comparison of aprotinin and lysone analogues in high-risk cardiac surgery. N Engl J Med. 2008;358:2319–31.PubMedCrossRef
112.
Mangano DT, Tudor IC, Dietzel C. Multicenter study of perioperative ischemia research group, ischemia research and education foundation. The risk associated with aprotinin in cardiac surgery. N Engl J Med. 2006;354:353–65.PubMedCrossRef
113.
Yang ZG, Chen WP, Wu LD. Effectiveness and safety of tranexamic acid in reducing blood loss in total knee arthroplasty: a meta-analysis. J Bone Joint Surg Am. 2012;94:1153–9.PubMedCrossRef
114.
Oremus K, Sostaric S, Trkulja V, Haspl M. Influence of tranexamic acid on postoperative autologous blood retransfusion in primary total hip and knee arthroplasty: a randomized controlled trial. Transfusion. 2014;54:31–41.PubMedCrossRef
115.
Meena S, Benazzo F, Dwivedi S, Ghiara M. Topica versus intravenous tranexamic acid in total knee arthroplasty. J Orthop Surg (Hong Kong). 2017;25:2309499016684300.
116.
Zhang P, Liang Y, Chen P, Fang Y, He J, Wang J. Intravenous versus topical tranexamic acid in primary total hip replacement. A meta-analysis. Medicine (Baltimore). 2016;95:e5573.CrossRef
117.
Drosos GI, Ververidis A, Valkanis C, Tripsianis G, Stavroulakis E, Vogiatzaki T, Kazakos K. A randomized comparative study of topical versus intravenous tranexamic acid administration in enhanced recovery after surgery (ERAS) total knee replacement. J Orthop. 2016;13:127–31.PubMedPubMedCentralCrossRef
118.
Tzatzairis TK, Drosos GI, Kotsios SE, Ververidis AN, Vogiatzaki TD, Kazakos KI. Intravenous vs topical tranexamic acid in total knee arthroplasty without tourniquet application: a randomized controlled study. J Arthroplasty. 2016;11:2465–70.CrossRef
119.
Sun X, Dong Q, Zhang YG. Intravenous versus topical tranexamic acid in primary total hip replacement: A systematic review and meta-analysis. Int J Surg. 2016;32:10–8.PubMedCrossRef
120.
Hsu CH, Lin PC, Kuo FC, Wang JW. A regime of two intravenous injections of tranexamic acid reduces blood loss in minimally invasive total hip arthroplasty: a prospective randomised double-blind study. Bone Joint J. 2015;97-B:905–10.PubMedCrossRef
121.
Xie J, Ma J, Yao H, Yue C, Pei F. Multiple boluses of intravenous tranexamic acid to reduce hidden blood loss after primary total knee arthroplasty without tourniquet: a randomized clinical trial. J Arthroplasty. 2016;31:2458–64.PubMedCrossRef
122.
Thipparampall AK, Gurajala I, Gopinath R. The effect of different dose regimens of tranexamic acid in reducing blood loss during hip surgery. Indian J Anaesth. 2017;61:235–9.PubMedPubMedCentral
123.
Chen JY, Chia SL, Lo NN, Yeo SJ. Intra-articular versus intravenous tranexamic acid in primary total knee replacement. Ann Transl Med. 2015;3:33.PubMedPubMedCentral
124.
Soni A, Saini R, Gulati A, Paul R, Bhatty S, Rajoli SR. Comparison between intravenous and intra-articular regimens of tranexamic acid in reducing blood loss during total knee arthroplasty. J Arthroplasty. 2014;29:1525–7.PubMedCrossRef
125.
Maniar RN, Kumar G, Singhi T, Nayak RM, Maniar PR. Most effective regimen of tranexamic acid in knee arthroplasty: a prospective randomized controlled study in 240 patients. Clin Orthop Related Res. 2012;470:2605–12.CrossRef
126.
Lin SY, Chen CH, Fu YC, Huang PJ, Chang JK, Huang HT. The efficacy of combined use of intraarticular and intravenous tranexamic acid on reducing blood loss and transfusion rate in total knee arthroplasty. J Arthroplasty. 2015;30:776–80.PubMedCrossRef
127.
Shang J, Wang H, Zheng B, Rui M, Wang Y. Combined intravenous and topical tranexamic acid versus intravenous use alone in primary total knee and hip arthroplasty: A meta-analysis of randomized controlled trials. Int J Surg. 2016;36(Pt A):324–9.PubMedCrossRef
128.
Duncan CM, Gillette BP, Jacob AK, Sierra RJ, Sanchez-Sotelo J, Smith HM. Venous thromboembolism and mortality associated with tranexamic acid use during total hip and knee arthroplasty. J Arthroplasty. 2015;30:2726.
129.
Husted H. Fast-track hip and knee arthroplasty: clinical and organizational aspects. Acta Orthop Suppl. 2012;83:1–39.PubMedCrossRef
130.
McDonald DA, Siegmeth R, Deakin AH, Kinninmonth AW, Scott NB. An enhanced recovery programme for primary total knee arthroplasty in the United Kingdom—follow up at one year. Knee. 2012;19:525–9.PubMedCrossRef
131.
Malviya A, Martin K, Harper I, Muller SD, Emmerson KP, Partington PF, Reed MR. Enhanced recovery program for hip and knee replacement reduces death rate. Acta Orthop. 2011;82:577–81.PubMedPubMedCentralCrossRef
132.
Nielsen CS, Jans Ø, Ørsnes T, Foss NB, Troelsen A, Husted H. Combined intra-articular and intravenous acid reduces blood loss in total knee arthroplasty: a randomized, double-blind, placebo-controlled trial. J Bone Joint Surg Am. 2016;98:835–41.PubMedCrossRef
133.
Jans Ø, Grevstad U, Mandøe H, Kehlet H, Johansson PI. A randomized trial of the effect of low dose epinephrine infusion in addition to tranexamic acid on bloos loss during total hip arthroplasty. Br J Anaesth. 2016;116:357–62.PubMedCrossRef
134.
Kelley TC, Tucker KK, Adams MJ, Dalury DF. Use of tranexamic acid results in decreased blood loss and decreased transfusions in patients undergoing staged total knee arthroplasty. Transfusion. 2014;54:26–30.PubMedCrossRef
135.
Gao F, Ma J, Sun W, Guo W, Li Z, Wang W. Topical fibrin sealant versus intravenous tranexamic acid for reducing blood loss following total knee arthroplasty: a systematic review and meta-analysis. Int J Surg. 2016;32:31–7.PubMedCrossRef
136.
Choufani C, Barbier O, Bajard X, Ollat D, Versier G. Medical and economic impact of a haemostatic sealant on the rate of transfusion after total knee arthroplasty. Transfus Clin Biol. 2015;22:22–9.PubMedCrossRef
137.
Randelli F, D’Anchise R, Ragone V, Serrao L, Cabitza P, Randelli P. Is the newest fibrin sealant an effective strategy to reduce blood loss after total knee arthroplasty? A randomized controlled study. J Arthroplasty. 2014;29:1516–20.PubMedCrossRef
138.
van Bodegom-Vos L, Voorn VM, So-Osman C, Vliet Vlieland TP, Dahan A, Koopman-van Gemert AW, Vehmeijer SB, Nelissen RG, Marang-van de Mheen PJ. Cell salvage in hip and knee arthroplasty: a meta-analysis of randomized controlled trials. J Bone Joint Surg Am. 2015;97:1012–21.PubMedCrossRef
139.
Haien Z, Yong J, Baoan M, Mingjun G, Qingyu F. Post-operative auto-transfusion in total hip or knee arthroplasty: a meta-analysis of randomized controlled trials. PLoS One. 2013;8:e55073 Epub 2013 Jan 25.PubMedPubMedCentralCrossRef
140.
Markar SR, Jones GG, Karthikesalingam A, Segaren N, Patel RV. Transfusion drains versus suction drains in total knee replacement: meta-analysis. Knee Surg Sports Traumatol Arthrosc. 2012;20:1766–72 Epub 2011 Nov 10.PubMedCrossRef
141.
Carless PA, Henry DA, Moxey AJ, O’Connell D, Brown T, Fergusson DA. Cell salvage for minimising perioperative allogenic blood transfusion. Cochrane Database Sys Rev. 2010;4:CD001888 Epub 2010 Apr 14.
142.
143.
Anderson LA, Engel GM, Bruckner JD, Stoddard GJ, Peters CL. Reduced bloos loss after total knee arthroplasty with local injection of bupivacaine and epinephrine. J Knee Surg. 2009;22:130–6.PubMedCrossRef
144.
Yang CY, Chang CW, Chen YN, Chang CH. Intra-articular injection of bupivacaine and epinephrine does not save blood loss after total knee arthroplasty. BJJ. 2016;98(Supp.1):68.
145.
Zeng WN, Liu JL, Wang FY, Chen C, Zhou Q, Yang L. Low-dose epinephrine plus tranexamic acid reduces early postoperative blood loss and inflammatory response: a randomized controlled trial. J Bone Joint Surg Am. 2018;100:295–304.PubMedCrossRef
146.
Morin AM, Wulf H. High volume local infiltration analgesia (LIA) for total hip and knee arthroplasty: a brief review on the current status. Anaesthesiol Intensivmed Notfallmed Schmerzther. 2011;46:84–6.CrossRef
147.
Andersen LØ, Kehlet H. Analgesic efficacy of local infiltration analgesia in hip and knee arthroplasty: a systematic review. Br J Anaesth. 2014;113:360–74.PubMedCrossRef
148.
Voorn VMA, Marang-van de Mheen PJ, van der Hout A, Hofstede SN, So-Osman C, van den Akker-van Marle ME, Kaptein AA, Stijnen T, Koopman-van Gemert AWMM, Dahan A, Vliet Vlieland TPMM, Nelissen RGHH, van Bodegom-Vos L. The effectiveness of a de-implementation strategy to reduce low-value blood management techniques in primary hip and knee arthroplasty: a pragmatic cluster-randomized controlled trial. Implement Sci. 2017;12:72.PubMedPubMedCentralCrossRef
149.
Nielsen CS, Gromov K, Jans Ø, Troelsen A, Husted H. No effect of a bipolar sealer on total blood loss or blood transfusion in nonseptic revision knee arthroplasty—a prospective study with matched retrospective controls. J Arthroplasty. 2017;32:177–82.PubMedCrossRef
150.
Rosenthal BD, Haughom BD, Levine BR. A retrospective analysis of hemostatic tehcniques in primary total knee arthroplasty: traditional electrocautery, bipolar sealer, and argon beam coagulation. Am J Orthop (Belle Mead NJ). 2016;45:E187–91.PubMed
151.
Huang Z, Ma J, Shen B, Yang J, Zhou Z, Kang P, Pei F. Use of a bipolar blood-sealing system during total joint arthroplasty. Orthopedics. 2015;38:757–63.PubMedCrossRef
152.
Kamath AF, Austin DC, Derman PB, Clement RC, Garino JP, Lee GC. Saline-coupled bipolar sealing in simultaneous bilateral total knee arthroplasty. Clin Orthop Surg. 2014;6:298–304.PubMedPubMedCentralCrossRef
153.
Marulanda GA, Krebs VE, Bierbaum BE, Goldberg VM, Ries M, Ulrich SD, Seyler TM, Mont MA. Hemostasis using a bipolar sealer in primary unilateral total knee arthroplasty. Am J Orthop (Belle Mead NJ). 2009;38:E179–83.PubMed
154.
Samdani AF, Torre-Healy A, Asghar J, Herlich AM, Betz RR. Strategies to reduce blood loss during posterior spinal fusion for neuromuscular scoliosis: a review of current techniques and experience with a unique bipolar electrocautery device. Surg Technol Int. 2008;17:243–8.PubMed
155.
Yim AP, Rendina EA, Hazelrigg SR, Chow LT, Lee TW, Wan S, Arifi AA. A new technological approach to nonanatomical pulmonary resection: saline enhanced thermal sealing. Ann Thorac Surg. 2002;74:1671–6.PubMedCrossRef
156.
Saltzman BM, Oni JK. A review of bipolar sealer use in modern total joint arthroplasty. Ann Orthop Rheumtaol. 2014;2:1015.
157.
Gardner MJ, Demetrakopoulos D, Klepchick PR, Mooar PA. The efficacy of autologous platelet gel in pain control and blood loss in total knee arthroplasty. An analysis of the haemoglobin, narcotic requirement and range of motion. Int Orthop. 2007;31:309–13.PubMedCrossRef
158.
Guerreiro JP, Danieli MV, Queiroz AO, Deffune E, Ferreira RR. Platelet-rich plasma (PRP) applied during total knee arthroplasty. Rev Bras Orthop. 2015;50:186–94.CrossRef
159.
Tingstad EM, Bratt SN, Hildenbrand KJ, O’Malley BA, Mitchell ER, Gaddis CE, Jacobson CA. Platelet-rich plasma does not decrease blood loss in total knee arthroplasty. Orthopedics. 2015;38:e434–6.PubMedCrossRef
160.
Schonauer C, Tessitore E, Barbagallo G, Albanese V, Moraci A. The use of local agents: bone wax, gelatin, collagen, oxidized cellulose. Eur Spine J. 2004;13(Suppl 1):S89–96.PubMedPubMedCentralCrossRef
161.
Moo IH, Chen JYQ, Pagkaliwaga EH, Tan SW, Poon KB. Bone wax is effective in reducing blood loss after total knee arthroplasty. J Arthroplasty. 2017;32:1483–7.PubMedCrossRef
162.
Solomon LB, Guevara C, Büchler L, Howie DW, Byard RW, Beck M. Does bone wax induce a chronic inflammatory articular reaction? Clin Orthop Relat Res. 2012;470:3207–12.PubMedPubMedCentralCrossRef
163.
Qian T, Ping S, Gang Z, Hua-Zi X, Hai-Xiao L. Extramedullary versus intramedullary femoral alignment technique in total knee arthroplasty: a meta-analysis of randomized controlled trials. J Orthop Surg Res. 2017;12:82.CrossRef
164.
Meding JB, Berend ME, Ritter MA, Galley MR, Malinzak RA. Intramedullary vs extramedullary femoral alignment guides: a 15-year follow-up of survivorship. J Arthroplasty. 2011;26:591–5.PubMedCrossRef
165.
Sehat KR, Evans RL, Newman JH. Hidden blood loss following hip and knee arthroplasty. Correct management of blood loss should take hidden loss into account. J Bone Joint Surg Br. 2004;86:561–5.PubMedCrossRef
166.
Senthil Kumar G, Von Arx OA, Pozo JL. Rate of blood loss over 48 hours following total knee replacement. Knee. 2005;12:307–9.PubMedCrossRef
167.
Brock TM, Sprowson AP, Muller S, Reed MR. Short-stretch inelastic compression bandage in knee swelling following total knee arthroplasty study (STICKS): study protocol for a randomised controlled feasibility study. Trials. 2015;16:87.PubMedPubMedCentralCrossRef
168.
Andersen LØ, Husted H, Otte KS, Kristensen BB, Kehelt HH. A compression bandage improves local infiltration analgesia in total knee arthroplasty. Acta Orthop. 2008;79:806–11.PubMedCrossRef
169.
Cheung A, Lykostratis H, Holloway I. Compression bandaging improves mobility following total knee replacement in an enhanced recovery setting. J Perioper Pract. 2014;24:84–6.PubMedCrossRef
170.
Pinsornsak P, Chumchuen S. Can a modified Robert Jones bandage after knee arthroplasty reduce blood loss? A prospective randomized controlled trial. Clin Orthop Relat Res. 2013;471:1677–81.PubMedPubMedCentralCrossRef
171.
Munk S, Jensen NJ, Andersen I, Kehlet J, Hansen TB. Effect of compression therapy on knee swelling and pain after total knee arthroplasty. Knee Surg Sports Traumatol Arthrosc. 2013;21:388–92.PubMedCrossRef
172.
Ni SH, Jiang WT, Guo L, Jin YH, Jiang TL, Zhao Y, Zhao J. Cryotherapy on postoperative rehabilitation of joint arthroplasty. Knee Surg Sports Traumatol Arthrosc. 2015;23:3354–61.PubMedCrossRef
173.
Adie S, Naylor JM, Harris IA. Cryotherapy after total knee arthroplasty a systemic review and meta-analysis of randomized controlled trials. J Arthroplasty. 2010;25:709–15.PubMedCrossRef
174.
Ruffilli A, Castagnini F, Traina F, Corneti I, Fenga D, Giannini S, Faldini C. Temperature-controlled continuous cold flow device after total knee arthroplasty: a randomized controlled trial study. J Knee Surg. 2017;30:675–81.PubMedCrossRef
175.
Wu Y, Yang T, Zeng Y, Si H, Li C, Shen B. Effect of different postoperative limb positions on blood loss and range of motion in total knee arthroplasty: an updated meta-analysis of randomized controlled trials. Int J Surg. 2017;37:15–23.PubMedCrossRef
176.
Faldini C, Traina F, De Fine M, Pedrini M, Sambri A. Post-operative limb position can influence blood loss and range of motion after total knee arthroplasty: a systematic review. Knee Surg Sports Traumatol Arthrosc. 2015;23:852–9.PubMedCrossRef
177.
Yang Y, Yong-Ming L, Pei-jian D, Jia L, Ying-ze Z. Leg position influences early blood loss and functional recovery following total knee arthroplasty: a randomized study. Int J Surg. 2015;23(Pt A):82–6.PubMedCrossRef
178.
Muňoz M, Ariza D, Campos A, Martin-Montańez E, Pavía J. The cost of post-operative shed blood salvage after total knee arthroplasty: an analysis of 1.093 consecutive procedures. Blood Transfus. 2013;11:260–71.PubMedPubMedCentral
179.
Kim YH, Cho SH, Kim RS. Drainage versus nondrainage in simultaneous bilateral total knee arthroplasties. Clin Orthop Related Res. 1998;347:188–93.CrossRef
180.
Kim YH, Cho SH, Kim RS. Drainage versus nondrainage in simultaneous bilateral total hip arthroplasties. J Arthroplasty. 1998;13:156–61.PubMedCrossRef
181.
Tai TW, Jou IM, Chang CW, Lai KA, Yang CY. Non-drainage is better than 4-hour clamping drainage in total knee arthroplasty. Orthopedics. 2010;33 Epub 2010 Mar 10.
182.
Esler CN, Blakeway C, Fiddian NJ. The use of a closed-suction drain in total knee arthroplasty. A prospective, randomised study. J Bone Joint Surg Br. 2003;85:215–7.PubMedCrossRef
183.
Mengal B, Aebi J, Rodriguez A, Lemaire R. A prospective randomized study of wound drainage versus non-drainage in primary total hip or knee arthroplasty. Rev Chir Orthop Reparatrice Appar Mot. 2001;87:29–39.PubMed
184.
Stucinskas J, Tarasevicius S, Cebatorius A, Robertsson O, Smailys A, Wingstrand H. Conventional drainage versus four hour clamping drainage after total knee arthroplasty in severe osteoarthritis: a prospective, randomised trial. Int Orthop. 2009;33:1275–8.PubMedCrossRef
185.
Raleigh E, Hing CB, Hanusiewicz AS, Fletcher SA, Price R. Drain clamping in knee arthroplasty, a randomized controlled trial. ANZ J Surg. 2007;77:333–5.PubMedCrossRef
186.
Yamada K, Imaizumi T, Uemura M, Takada N, Kim Y. Comparison between 1-hour and 24-hours drain clamping using diluted epinephrine solution after total knee arthroplasty. J Arthroplasty. 2011;16:458–62.CrossRef
187.
Pornrattanamaneewong C, Narkbunnam R, Siriwattanasakul P, Chareancholvanich K. Three-hour interval drain clamping reduces postoperative bleeding in total knee arthroplasty: a prospective randomized controlled trial. Arch Orthop Trauma Surg. 2012;132:1059–63.PubMedCrossRef
188.
Liao L, Chen Y, Tang Q, Chen XY, Wang WC. Tranexamic acid plus drain-clamping can reduce blood loss in total knee arthroplasty: A systematic review and meta-analysis. Int J Surg. 2018;52:334–41.PubMedCrossRef
189.
Chareancholvanich K, Siriwattanasakul P, Narkbunnam R, Pornrattanamaenewong C. Temporary clamping of drain combined with tranexamic acid reduce blood loss after total knee arthroplasty: a prospective randomized controlled trial. BMC Musculoskelet Disord. 2012;13:124.PubMedPubMedCentralCrossRef
190.
Zan P, Yao JJ, Fan L, Yang Y, Zhou Z, Wu Z, Zhu C, Yang D, Li G. Efficacy of a four-hour drainage clamping technique in the reduction of blood loss following total hip arthroplasty: a prospective cohort study. Med Sci Monit. 2017;23:2708–14.PubMedPubMedCentralCrossRef
191.
Xu X, Li X, Liu W, Wang Z. Longtime soaking of high concentration tranexamic acid in total hip arthroplasty: A prospective randomized controlled trial in 224 patients. Pak J Med Sci. 2015;31:1306–11.PubMedPubMedCentralCrossRef
192.
Zhang S, Xu B, Huang Q, Yao H, Xie J, Pei F. Early Removal of drainage tube after fast-track primary total knee arthroplasty. J Knee Surg. 2017;30:571–6.PubMedCrossRef
193.
Arsoy D, Giori NJ, Woolson ST. Mobile compression reduces bleeding-related readmissions and wound complications after THA and TKA. Clin Orthop Relat Res. 2018;476:381–7.PubMedPubMedCentralCrossRef
194.
Geerts WH, Pineo GF, Heit JA, Berqqvist D, Lassen MR, Colwell CW, Ray JG. Prevention of venous thromboembolism: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy. Chest. 2004;126:338S–400S.PubMedCrossRef
195.
Nicolaides AN, Breddin HK, Fareed J, Goldhaber S, Haas S, Hull R, Kalodiki E, Myers K, Samama M, Sasahara A, Cardiovascular disease educational and research trust and the international union of angiology. Prevention of venous thromboembolism. International Consensus Statement. Guidelines compiled in accordance with the scientific evidence. Int Angiol. 2001;20:1–37.PubMedCrossRef
196.
Tyagi V, Tomaszwewski P, Lukasiewicz A, Theriault S, Pelker R. The role of intraoperative intermittend pneumatic compression devices in venous thromboembolism prophylaxis in total hip and total knee arthroplasty. Orthopedics. 2018;41:e98–e103.PubMedCrossRef
197.
Caprini JA. Thrombosis risk assessment as a guide to quality patient care. Dis Mon. 2005;51:70–8.PubMedCrossRef
198.
Husted H, Otte KS, Kristensen BB, Ørsnes T, Wong C, Kehlet H. Low risk of thromboembolic complications after fast-track hip and knee arthroplasty. Acta Orthop. 2010;81:599–605.PubMedPubMedCentralCrossRef
199.
Chandrasekaran S, Ariaretnam SK, Tsung J, Dickison D. Early mobilization after total knee replacement reduces the incidence of deep venous thrombosis. ANZ J Surg. 2009;79:526–9.PubMedCrossRef
200.
Wellman SS, Murphy AC, Gulcynski D, Murphy SB. Implementation of an accelerated mobilization protocol following primary total hip arthroplasty: impact on length of stay and disposition. Curr Rev Musculoskelet Med. 2011;4:84–90.PubMedPubMedCentralCrossRef
201.
Bonutti PM, Sodhi N, Patel YH, Sultan AA, Khlopas A, Chughtai M, Kolisek FR, Williams N, Mont MA. Novel venous thromboembolic disease (VTED) prophylaxis for total knee arthroplasty-aspirin and fish oil. Ann Transl Med. 2017;5(Suppl 3):S30.PubMedPubMedCentralCrossRef
202.
Roberts M, Ahya R, Greaves M, Maffulli N. A one-centre prospective audit of peri- and postoperative blood loss and transfusion practice in patients undergoing hip or knee replacement surgery. Ann R Coll Surg Engl. 2000;82:4–8.
203.
Voorn VMA, van Bodegom-Vos L, So-Osman C. Towards a systematic approach for (de)implementation of patient blood management strategies. Transfus Med. 2018;28:158–67.PubMedCrossRef
Metadata
Title
Blood management in fast-track orthopedic surgery: an evidence-based narrative review
Authors
Federico Pennestrì
Nicola Maffulli
Paolo Sirtori
Paolo Perazzo
Francesco Negrini
Giuseppe Banfi
Giuseppe M Peretti
Publication date
01-12-2019
Publisher
BioMed Central
Published in
Journal of Orthopaedic Surgery and Research / Issue 1/2019
Electronic ISSN: 1749-799X
DOI
https://doi.org/10.1186/s13018-019-1296-5

Other articles of this Issue 1/2019

Journal of Orthopaedic Surgery and Research 1/2019 Go to the issue

Research article

How coronal alignment affects distal femoral anatomy: an MRI-based comparison of varus and valgus knees

Research article

Biomechanical comparison of posterior intermediate screw fixation techniques with hybrid monoaxial and polyaxial pedicle screws in the treatment of thoracolumbar burst fracture: a finite element study

Research article

Risk analysis and clinical outcomes of intraoperative periprosthetic fractures: a retrospective study of 481 bipolar hemiarthroplasties

Research article

Comparison of three different internal fixation implants in treatment of femoral neck fracture—a finite element analysis

Research article

Risk factors for the formation of double-contour sign and tophi in gout

Research article

Recruitment of Brd3 and Brd4 to acetylated chromatin is essential for proinflammatory cytokine-induced matrix-degrading enzyme expression