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World Journal of Emergency Surgery
Published in: World Journal of Emergency Surgery 1/2018

Open Access 01-12-2018 | Research article

Prospective Observational Study on acute Appendicitis Worldwide (POSAW)

Authors: Massimo Sartelli, Gian L. Baiocchi, Salomone Di Saverio, Francesco Ferrara, Francesco M. Labricciosa, Luca Ansaloni, Federico Coccolini, Deepak Vijayan, Ashraf Abbas, Hariscine K. Abongwa, John Agboola, Adamu Ahmed, Lali Akhmeteli, Nezih Akkapulu, Seckin Akkucuk, Fatih Altintoprak, Aurelia L. Andreiev, Dimitrios Anyfantakis, Boiko Atanasov, Miklosh Bala, Dimitrios Balalis, Oussama Baraket, Giovanni Bellanova, Marcelo Beltran, Renato Bessa Melo, Roberto Bini, Konstantinos Bouliaris, Daniele Brunelli, Adrian Castillo, Marco Catani, Asri Che Jusoh, Alain Chichom-Mefire, Gianfranco Cocorullo, Raul Coimbra, Elif Colak, Silvia Costa, Koray Das, Samir Delibegovic, Zaza Demetrashvili, Isidoro Di Carlo, Nadezda Kiseleva, Tamer El Zalabany, Mario Faro, Margarida Ferreira, Gustavo P. Fraga, Mahir Gachabayov, Wagih M. Ghnnam, Teresa Giménez Maurel, Georgios Gkiokas, Carlos A. Gomes, Ewen Griffiths, Ali Guner, Sanjay Gupta, Andreas Hecker, Elcio S. Hirano, Adrien Hodonou, Martin Hutan, Orestis Ioannidis, Arda Isik, Georgy Ivakhov, Sumita Jain, Mantas Jokubauskas, Aleksandar Karamarkovic, Saila Kauhanen, Robin Kaushik, Alfie Kavalakat, Jakub Kenig, Vladimir Khokha, Desmond Khor, Dennis Kim, Jae I. Kim, Victor Kong, Konstantinos Lasithiotakis, Pedro Leão, Miguel Leon, Andrey Litvin, Varut Lohsiriwat, Eudaldo López-Tomassetti Fernandez, Eftychios Lostoridis, James Maciel, Piotr Major, Ana Dimova, Dimitrios Manatakis, Athanasio Marinis, Aleix Martinez-Perez, Sanjay Marwah, Michael McFarlane, Cristian Mesina, Michał Pędziwiatr, Nickos Michalopoulos, Evangelos Misiakos, Ali Mohamedahmed, Radu Moldovanu, Giulia Montori, Raghuveer Mysore Narayana, Ionut Negoi, Ioannis Nikolopoulos, Giuseppe Novelli, Viktors Novikovs, Iyiade Olaoye, Abdelkarim Omari, Carlos A. Ordoñez, Mouaqit Ouadii, Zeynep Ozkan, Ajay Pal, Gian M. Palini, Lars I. Partecke, Francesco Pata, Michał Pędziwiatr, Gerson A. Pereira Júnior, Tadeja Pintar, Magdalena Pisarska, Cesar F. Ploneda-Valencia, Konstantinos Pouggouras, Vinod Prabhu, Padmakumar Ramakrishnapillai, Jean-Marc Regimbeau, Marianne Reitz, Daniel Rios-Cruz, Sten Saar, Boris Sakakushev, Charalampos Seretis, Alexander Sazhin, Vishal Shelat, Matej Skrovina, Dmitry Smirnov, Charalampos Spyropoulos, Marcin Strzałka, Peep Talving, Ricardo A. Teixeira Gonsaga, George Theobald, Gia Tomadze, Myftar Torba, Cristian Tranà, Jan Ulrych, Mustafa Y. Uzunoğlu, Alin Vasilescu, Savino Occhionorelli, Aurélien Venara, Andras Vereczkei, Nereo Vettoretto, Nutu Vlad, Maciej Walędziak, Tonguç U. Yilmaz, Kuo-Ching Yuan, Cui Yunfeng, Justas Zilinskas, Gérard Grelpois, Fausto Catena

Published in: World Journal of Emergency Surgery | Issue 1/2018

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Abstract

Background

Acute appendicitis (AA) is the most common surgical disease, and appendectomy is the treatment of choice in the majority of cases. A correct diagnosis is key for decreasing the negative appendectomy rate. The management can become difficult in case of complicated appendicitis. The aim of this study is to describe the worldwide clinical and diagnostic work-up and management of AA in surgical departments.

Methods

This prospective multicenter observational study was performed in 116 worldwide surgical departments from 44 countries over a 6-month period (April 1, 2016–September 30, 2016). All consecutive patients admitted to surgical departments with a clinical diagnosis of AA were included in the study.

Results

A total of 4282 patients were enrolled in the POSAW study, 1928 (45%) women and 2354 (55%) men, with a median age of 29 years. Nine hundred and seven (21.2%) patients underwent an abdominal CT scan, 1856 (43.3%) patients an US, and 285 (6.7%) patients both CT scan and US. A total of 4097 (95.7%) patients underwent surgery; 1809 (42.2%) underwent open appendectomy and 2215 (51.7%) had laparoscopic appendectomy. One hundred eighty-five (4.3%) patients were managed conservatively. Major complications occurred in 199 patients (4.6%). The overall mortality rate was 0.28%.

Conclusions

The results of the present study confirm the clinical value of imaging techniques and prognostic scores. Appendectomy remains the most effective treatment of acute appendicitis. Mortality rate is low.
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Metadata
Title
Prospective Observational Study on acute Appendicitis Worldwide (POSAW)
Authors
Massimo Sartelli
Gian L. Baiocchi
Salomone Di Saverio
Francesco Ferrara
Francesco M. Labricciosa
Luca Ansaloni
Federico Coccolini
Deepak Vijayan
Ashraf Abbas
Hariscine K. Abongwa
John Agboola
Adamu Ahmed
Lali Akhmeteli
Nezih Akkapulu
Seckin Akkucuk
Fatih Altintoprak
Aurelia L. Andreiev
Dimitrios Anyfantakis
Boiko Atanasov
Miklosh Bala
Dimitrios Balalis
Oussama Baraket
Giovanni Bellanova
Marcelo Beltran
Renato Bessa Melo
Roberto Bini
Konstantinos Bouliaris
Daniele Brunelli
Adrian Castillo
Marco Catani
Asri Che Jusoh
Alain Chichom-Mefire
Gianfranco Cocorullo
Raul Coimbra
Elif Colak
Silvia Costa
Koray Das
Samir Delibegovic
Zaza Demetrashvili
Isidoro Di Carlo
Nadezda Kiseleva
Tamer El Zalabany
Mario Faro
Margarida Ferreira
Gustavo P. Fraga
Mahir Gachabayov
Wagih M. Ghnnam
Teresa Giménez Maurel
Georgios Gkiokas
Carlos A. Gomes
Ewen Griffiths
Ali Guner
Sanjay Gupta
Andreas Hecker
Elcio S. Hirano
Adrien Hodonou
Martin Hutan
Orestis Ioannidis
Arda Isik
Georgy Ivakhov
Sumita Jain
Mantas Jokubauskas
Aleksandar Karamarkovic
Saila Kauhanen
Robin Kaushik
Alfie Kavalakat
Jakub Kenig
Vladimir Khokha
Desmond Khor
Dennis Kim
Jae I. Kim
Victor Kong
Konstantinos Lasithiotakis
Pedro Leão
Miguel Leon
Andrey Litvin
Varut Lohsiriwat
Eudaldo López-Tomassetti Fernandez
Eftychios Lostoridis
James Maciel
Piotr Major
Ana Dimova
Dimitrios Manatakis
Athanasio Marinis
Aleix Martinez-Perez
Sanjay Marwah
Michael McFarlane
Cristian Mesina
Michał Pędziwiatr
Nickos Michalopoulos
Evangelos Misiakos
Ali Mohamedahmed
Radu Moldovanu
Giulia Montori
Raghuveer Mysore Narayana
Ionut Negoi
Ioannis Nikolopoulos
Giuseppe Novelli
Viktors Novikovs
Iyiade Olaoye
Abdelkarim Omari
Carlos A. Ordoñez
Mouaqit Ouadii
Zeynep Ozkan
Ajay Pal
Gian M. Palini
Lars I. Partecke
Francesco Pata
Michał Pędziwiatr
Gerson A. Pereira Júnior
Tadeja Pintar
Magdalena Pisarska
Cesar F. Ploneda-Valencia
Konstantinos Pouggouras
Vinod Prabhu
Padmakumar Ramakrishnapillai
Jean-Marc Regimbeau
Marianne Reitz
Daniel Rios-Cruz
Sten Saar
Boris Sakakushev
Charalampos Seretis
Alexander Sazhin
Vishal Shelat
Matej Skrovina
Dmitry Smirnov
Charalampos Spyropoulos
Marcin Strzałka
Peep Talving
Ricardo A. Teixeira Gonsaga
George Theobald
Gia Tomadze
Myftar Torba
Cristian Tranà
Jan Ulrych
Mustafa Y. Uzunoğlu
Alin Vasilescu
Savino Occhionorelli
Aurélien Venara
Andras Vereczkei
Nereo Vettoretto
Nutu Vlad
Maciej Walędziak
Tonguç U. Yilmaz
Kuo-Ching Yuan
Cui Yunfeng
Justas Zilinskas
Gérard Grelpois
Fausto Catena
Publication date
01-12-2018
Publisher
BioMed Central
Published in
World Journal of Emergency Surgery / Issue 1/2018
Electronic ISSN: 1749-7922
DOI
https://doi.org/10.1186/s13017-018-0179-0

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