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Published in: Radiation Oncology 1/2018

Open Access 01-12-2018 | Research

Reliability of the gamma index analysis as a verification method of volumetric modulated arc therapy plans

Authors: Jong Min Park, Jung-in Kim, So-Yeon Park, Do Hoon Oh, Sang-Tae Kim

Published in: Radiation Oncology | Issue 1/2018

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Abstract

Background

We investigate the gamma passing rate (GPR) consistency when applying different types of gamma analyses, linacs, and dosimeters for volumetric modulated arc therapy (VMAT).

Methods

A total of 240 VMAT plans for various treatment sites, which were generated with Trilogy (140 plans) and TrueBeam STx (100 plans), were retrospectively selected. For each VMAT plan, planar dose distributions were measured with both MapCHECK2 and ArcCHECK dosimeters. During the planar dose distribution measurements, the actual multileaf collimator (MLC) positions, gantry angles, and delivered monitor units were recorded and compared to the values in the original VMAT plans to calculate mechanical errors. For each VMAT plan, both the global and local gamma analyses were performed with 3%/3 mm, 2%/2 mm, 2%/1 mm, 1%/2 mm, and 1%/1 mm. The Pearson correlation coefficients (r) were calculated 1) between the global and the local GPRs, 2) between GPRs with the MapCHECK2 and the ArcCHECK dosimeters, 3) and between GPRs and the mechanical errors during the VMAT delivery.

Results

For the MapCHECK2 measurements, strong correlations between the global and local GPRs were observed only with 1%/2 mm and 1%/1 mm (r > 0.8 with p < 0.001), while weak or no correlations were observed for the ArcCHECK measurement. Between the MapCHECK2 and ArcCHECK measurements, the global GPRs showed no correlations (all with p > 0.05), while the local GPRs showed moderate correlations only with 2%/1 mm and 1%/1 mm for TrueBeam STx (r > 0.5 with p < 0.001). Both the global and local GPRs always showed weak or no correlations with the MLC positional errors except for the GPRs of MapCHECK2 with 1%/2 mm and 1%/1 mm for TrueBeam STx and the GPR of ArcCHECK with 1%/2 mm for Trilogy (r < − 0.5 with p < 0.001).

Conclusions

The GPRs varied according to the types of gamma analyses, dosimeters, and linacs. Therefore, each institution should carefully establish their own gamma analysis protocol by determining the type of gamma index analysis and the gamma criterion with their own linac and their own dosimeter.
Literature
1.
go back to reference Ezzell GA, Galvin JM, Low D, Palta JR, Rosen I, Sharpe MB, Xia P, Xiao Y, Xing L, Yu CX, et al. Guidance document on delivery, treatment planning, and clinical implementation of IMRT: report of the IMRT subcommittee of the AAPM radiation therapy committee. Med Phys. 2003;30:2089–115.CrossRefPubMed Ezzell GA, Galvin JM, Low D, Palta JR, Rosen I, Sharpe MB, Xia P, Xiao Y, Xing L, Yu CX, et al. Guidance document on delivery, treatment planning, and clinical implementation of IMRT: report of the IMRT subcommittee of the AAPM radiation therapy committee. Med Phys. 2003;30:2089–115.CrossRefPubMed
2.
go back to reference Zhang P, Happersett L, Hunt M, Jackson A, Zelefsky M, Mageras G. Volumetric modulated arc therapy: planning and evaluation for prostate cancer cases. Int J Radiat Oncol Biol Phys. 2010;76:1456–62.CrossRefPubMed Zhang P, Happersett L, Hunt M, Jackson A, Zelefsky M, Mageras G. Volumetric modulated arc therapy: planning and evaluation for prostate cancer cases. Int J Radiat Oncol Biol Phys. 2010;76:1456–62.CrossRefPubMed
3.
go back to reference Brahme A. Optimization of stationary and moving beam radiation therapy techniques. Radiother Oncol. 1988;12:129–40.CrossRefPubMed Brahme A. Optimization of stationary and moving beam radiation therapy techniques. Radiother Oncol. 1988;12:129–40.CrossRefPubMed
4.
go back to reference Otto K. Volumetric modulated arc therapy: IMRT in a single gantry arc. Med Phys. 2008;35:310–7.CrossRef Otto K. Volumetric modulated arc therapy: IMRT in a single gantry arc. Med Phys. 2008;35:310–7.CrossRef
5.
go back to reference Du W, Cho SH, Zhang X, Hoffman KE, Kudchadker RJ. Quantification of beam complexity in intensity-modulated radiation therapy treatment plans. Med Phys. 2014;41:021716.CrossRefPubMed Du W, Cho SH, Zhang X, Hoffman KE, Kudchadker RJ. Quantification of beam complexity in intensity-modulated radiation therapy treatment plans. Med Phys. 2014;41:021716.CrossRefPubMed
6.
go back to reference Park JM, Park SY, Kim H. Modulation index for VMAT considering both mechanical and dose calculation uncertainties. Phys Med Biol. 2015;60:7101–25.CrossRefPubMed Park JM, Park SY, Kim H. Modulation index for VMAT considering both mechanical and dose calculation uncertainties. Phys Med Biol. 2015;60:7101–25.CrossRefPubMed
8.
go back to reference Li R, Xing L. An adaptive planning strategy for station parameter optimized radiation therapy (SPORT): segmentally boosted VMAT. Med Phys. 2013;40:050701.CrossRefPubMedPubMedCentral Li R, Xing L. An adaptive planning strategy for station parameter optimized radiation therapy (SPORT): segmentally boosted VMAT. Med Phys. 2013;40:050701.CrossRefPubMedPubMedCentral
9.
go back to reference Masi L, Doro R, Favuzza V, Cipressi S, Livi L. Impact of plan parameters on the dosimetric accuracy of volumetric modulated arc therapy. Med Phys. 2013;40:071718.CrossRefPubMed Masi L, Doro R, Favuzza V, Cipressi S, Livi L. Impact of plan parameters on the dosimetric accuracy of volumetric modulated arc therapy. Med Phys. 2013;40:071718.CrossRefPubMed
10.
go back to reference Nicolini G, Clivio A, Cozzi L, Fogliata A, Vanetti E. On the impact of dose rate variation upon RapidArc implementation of volumetric modulated are therapy. Med Phys. 2011;38:264–71.CrossRefPubMed Nicolini G, Clivio A, Cozzi L, Fogliata A, Vanetti E. On the impact of dose rate variation upon RapidArc implementation of volumetric modulated are therapy. Med Phys. 2011;38:264–71.CrossRefPubMed
11.
go back to reference Fredh A, Scherman JB, Fog LS, Munck af Rosenschold P. Patient QA systems for rotational radiation therapy: a comparative experimental study with intentional errors. Med Phys. 2013;40:031716.CrossRefPubMed Fredh A, Scherman JB, Fog LS, Munck af Rosenschold P. Patient QA systems for rotational radiation therapy: a comparative experimental study with intentional errors. Med Phys. 2013;40:031716.CrossRefPubMed
12.
go back to reference Heilemann G, Poppe B, Laub W. On the sensitivity of common gamma-index evaluation methods to MLC misalignments in Rapidarc quality assurance. Med Phys. 2013;40:031702.CrossRefPubMed Heilemann G, Poppe B, Laub W. On the sensitivity of common gamma-index evaluation methods to MLC misalignments in Rapidarc quality assurance. Med Phys. 2013;40:031702.CrossRefPubMed
13.
go back to reference Hussein M, Rowshanfarzad P, Ebert MA, Nisbet A, Clark CH. A comparison of the gamma index analysis in various commercial IMRT/VMAT QA systems. Radiother Oncol. 2013;109:370–6.CrossRefPubMed Hussein M, Rowshanfarzad P, Ebert MA, Nisbet A, Clark CH. A comparison of the gamma index analysis in various commercial IMRT/VMAT QA systems. Radiother Oncol. 2013;109:370–6.CrossRefPubMed
14.
go back to reference Low DA, Dempsey JF. Evaluation of the gamma dose distribution comparison method. Med Phys. 2003;30:2455–64.CrossRefPubMed Low DA, Dempsey JF. Evaluation of the gamma dose distribution comparison method. Med Phys. 2003;30:2455–64.CrossRefPubMed
15.
go back to reference Low DA, Harms WB, Mutic S, Purdy JA. A technique for the quantitative evaluation of dose distributions. Med Phys. 1998;25:656–61.CrossRefPubMed Low DA, Harms WB, Mutic S, Purdy JA. A technique for the quantitative evaluation of dose distributions. Med Phys. 1998;25:656–61.CrossRefPubMed
16.
go back to reference Van Dyk J, Barnett RB, Cygler JE, Shragge PC. Commissioning and quality assurance of treatment planning computers. Int J Radiat Oncol Biol Phys. 1993;26:261–73.CrossRefPubMed Van Dyk J, Barnett RB, Cygler JE, Shragge PC. Commissioning and quality assurance of treatment planning computers. Int J Radiat Oncol Biol Phys. 1993;26:261–73.CrossRefPubMed
17.
go back to reference Jin X, Yan H, Han C, Zhou Y, Yi J, Xie C. Correlation between gamma index passing rate and clinical dosimetric difference for pre-treatment 2D and 3D volumetric modulated arc therapy dosimetric verification. Br J Radiol. 2015;88:20140577.CrossRefPubMedPubMedCentral Jin X, Yan H, Han C, Zhou Y, Yi J, Xie C. Correlation between gamma index passing rate and clinical dosimetric difference for pre-treatment 2D and 3D volumetric modulated arc therapy dosimetric verification. Br J Radiol. 2015;88:20140577.CrossRefPubMedPubMedCentral
18.
19.
go back to reference Rozendaal RA, Mijnheer BJ, van Herk M, Mans A. In vivo portal dosimetry for head-and-neck VMAT and lung IMRT: linking gamma-analysis with differences in dose-volume histograms of the PTV. Radiother Oncol. 2014;112:396–401.CrossRefPubMed Rozendaal RA, Mijnheer BJ, van Herk M, Mans A. In vivo portal dosimetry for head-and-neck VMAT and lung IMRT: linking gamma-analysis with differences in dose-volume histograms of the PTV. Radiother Oncol. 2014;112:396–401.CrossRefPubMed
20.
go back to reference Huang JY, Pulliam KB, McKenzie EM, Followill DS, Kry SF. Effects of spatial resolution and noise on gamma analysis for IMRT QA. J Appl Clin Med Phys. 2014;15:4690.CrossRefPubMedPubMedCentral Huang JY, Pulliam KB, McKenzie EM, Followill DS, Kry SF. Effects of spatial resolution and noise on gamma analysis for IMRT QA. J Appl Clin Med Phys. 2014;15:4690.CrossRefPubMedPubMedCentral
21.
go back to reference Almond PR, Biggs PJ, Coursey BM, Hanson WF, Huq MS, Nath R, Rogers DW. AAPM’s TG-51 protocol for clinical reference dosimetry of high-energy photon and electron beams. Med Phys. 1999;26:1847–70.CrossRefPubMed Almond PR, Biggs PJ, Coursey BM, Hanson WF, Huq MS, Nath R, Rogers DW. AAPM’s TG-51 protocol for clinical reference dosimetry of high-energy photon and electron beams. Med Phys. 1999;26:1847–70.CrossRefPubMed
22.
go back to reference Bailey DW, Spaans JD, Kumaraswamy LK, Podgorsak MB. The MapCHECK measurement uncertainty function and its effect on planar dose pass rates. J Appl Clin Med Phys. 2016;17:165–73.CrossRefPubMedPubMedCentral Bailey DW, Spaans JD, Kumaraswamy LK, Podgorsak MB. The MapCHECK measurement uncertainty function and its effect on planar dose pass rates. J Appl Clin Med Phys. 2016;17:165–73.CrossRefPubMedPubMedCentral
23.
go back to reference Klein EE, Hanley J, Bayouth J, Yin FF, Simon W, Dresser S, Serago C, Aguirre F, Ma L, Arjomandy B, et al. Task group 142 report: quality assurance of medical accelerators. Med Phys. 2009;36:4197–212.CrossRef Klein EE, Hanley J, Bayouth J, Yin FF, Simon W, Dresser S, Serago C, Aguirre F, Ma L, Arjomandy B, et al. Task group 142 report: quality assurance of medical accelerators. Med Phys. 2009;36:4197–212.CrossRef
24.
go back to reference Neal B, Ahmed M, Kathuria K, Watkins T, Wijesooriya K, Siebers J. A clinically observed discrepancy between image-based and log-based MLC positions. Med Phys. 2016;43:2933–5.CrossRefPubMed Neal B, Ahmed M, Kathuria K, Watkins T, Wijesooriya K, Siebers J. A clinically observed discrepancy between image-based and log-based MLC positions. Med Phys. 2016;43:2933–5.CrossRefPubMed
25.
go back to reference Kutcher GJ, Coia L, Gillin M, Hanson WF, Leibel S, Morton RJ, Palta JR, Purdy JA, Reinstein LE, Svensson GK, et al. Comprehensive QA for radiation oncology: report of AAPM radiation therapy committee task group 40. Med Phys. 1994;21:581–618.CrossRef Kutcher GJ, Coia L, Gillin M, Hanson WF, Leibel S, Morton RJ, Palta JR, Purdy JA, Reinstein LE, Svensson GK, et al. Comprehensive QA for radiation oncology: report of AAPM radiation therapy committee task group 40. Med Phys. 1994;21:581–618.CrossRef
26.
go back to reference Park JM, Wu HG, Kim JH, Carlson JN, Kim K. The effect of MLC speed and acceleration on the plan delivery accuracy of VMAT. Br J Radiol. 2015;88:20140698.CrossRefPubMedPubMedCentral Park JM, Wu HG, Kim JH, Carlson JN, Kim K. The effect of MLC speed and acceleration on the plan delivery accuracy of VMAT. Br J Radiol. 2015;88:20140698.CrossRefPubMedPubMedCentral
27.
go back to reference Kim JI, Choi CH, Wu HG, Kim JH, Kim K, Park JM. Correlation analysis between 2D and quasi-3D gamma evaluations for both intensity-modulated radiation therapy and volumetric modulated arc therapy. Oncotarget. 2016;8(3):5449–59. Kim JI, Choi CH, Wu HG, Kim JH, Kim K, Park JM. Correlation analysis between 2D and quasi-3D gamma evaluations for both intensity-modulated radiation therapy and volumetric modulated arc therapy. Oncotarget. 2016;8(3):5449–59.
28.
go back to reference Kim JI, Park SY, Kim HJ, Kim JH, Ye SJ, Park JM. The sensitivity of gamma-index method to the positioning errors of high-definition MLC in patient-specific VMAT QA for SBRT. Radiat Oncol. 2014;9:167.CrossRefPubMedPubMedCentral Kim JI, Park SY, Kim HJ, Kim JH, Ye SJ, Park JM. The sensitivity of gamma-index method to the positioning errors of high-definition MLC in patient-specific VMAT QA for SBRT. Radiat Oncol. 2014;9:167.CrossRefPubMedPubMedCentral
Metadata
Title
Reliability of the gamma index analysis as a verification method of volumetric modulated arc therapy plans
Authors
Jong Min Park
Jung-in Kim
So-Yeon Park
Do Hoon Oh
Sang-Tae Kim
Publication date
01-12-2018
Publisher
BioMed Central
Published in
Radiation Oncology / Issue 1/2018
Electronic ISSN: 1748-717X
DOI
https://doi.org/10.1186/s13014-018-1123-x

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