Skip to main content
Top
Published in: Radiation Oncology 1/2018

Open Access 01-12-2018 | Research

Optimal collimator rotation based on the outline of multiple brain targets in VMAT

Authors: Jung-in Kim, Beom Seok Ahn, Chang Heon Choi, Jong Min Park, So-Yeon Park

Published in: Radiation Oncology | Issue 1/2018

Login to get access

Abstract

Background

The aim of this study was to investigate the dosimetric quality in volumetric modulated arc therapy (VMAT) plans with optimal collimator angles that can represent the outline of multiple brain targets.

Methods

Twenty patients with multiple target volumes in the brain cases were selected retrospectively. To better represent the outline of the multiple brain targets, four conformal arc plans were generated for each patient using one full arc with four collimator settings. The optimal collimator angles calculated from the integrated multi-leaf collimator (MLC) aperture that had the smallest aperture size for certain collimator settings of the conformal arc plan were selected. VMAT plans with the optimal collimator angles with angular sections of 40° and 60° (Colli-VMAT (40°), Colli-VMAT (60°)) were generated, followed by evaluation of field sizes, dose-volumetric parameters and total monitor units (MUs).

Results

Patient-averaged values of field sizes for Colli-VMAT (40°) (111.5 cm2) were lowest and 1.3 times smaller than those for Std-VMAT (143.6 cm2). Colli-VMAT plans improved sparing of most normal organs but for brain stem and left parotid gland. For the total MUs, the averaged values obtained with the Colli-VMAT (40°) (390 ± 148 MU) were smaller than those obtained with the Std-VMAT (472 ± 235 MU).

Conclusions

The Colli-VMAT plans with smaller angular sections could be suitable in the clinic for multiple brain targets as well as for irregularly shaped targets. Determination of the optimal collimator rotation generally showed good normal tissue sparing and MU reduction for multiple brain targets.
Literature
1.
2.
go back to reference Park JM, Kim JI, Heon Choi C, Chie EK, Kim IH, Ye SJ. Photon energy-modulated radiotherapy: Monte Carlo simulation and treatment planning study. Med Phys. 2012;39:1265–77.CrossRefPubMed Park JM, Kim JI, Heon Choi C, Chie EK, Kim IH, Ye SJ. Photon energy-modulated radiotherapy: Monte Carlo simulation and treatment planning study. Med Phys. 2012;39:1265–77.CrossRefPubMed
3.
go back to reference Cozzi L, Dinshaw KA, Shrivastava SK, Mahantshetty U, Engineer R, Deshpande DD, et al. A treatment planning study comparing volumetric arc modulation with RapidArc and fixed field IMRT for cervix uteri radiotherapy. Radiother Oncol. 2008;89:180–91.CrossRefPubMed Cozzi L, Dinshaw KA, Shrivastava SK, Mahantshetty U, Engineer R, Deshpande DD, et al. A treatment planning study comparing volumetric arc modulation with RapidArc and fixed field IMRT for cervix uteri radiotherapy. Radiother Oncol. 2008;89:180–91.CrossRefPubMed
4.
go back to reference Kjaer-Kristoffersen F, Ohlhues L, Medin J, Korreman S. RapidArc volumetric modulated therapy planning for prostate cancer patients. Acta Oncol. 2009;48:227–32.CrossRefPubMed Kjaer-Kristoffersen F, Ohlhues L, Medin J, Korreman S. RapidArc volumetric modulated therapy planning for prostate cancer patients. Acta Oncol. 2009;48:227–32.CrossRefPubMed
5.
go back to reference Fogliata A, Clivio A, Nicolini G, Vanetti E, Cozzi L. Intensity modulation with photons for benign intracranial tumours: a planning comparison of volumetric single arc, helical arc and fixed gantry techniques. Radiother Oncol. 2008;89:254–62.CrossRefPubMed Fogliata A, Clivio A, Nicolini G, Vanetti E, Cozzi L. Intensity modulation with photons for benign intracranial tumours: a planning comparison of volumetric single arc, helical arc and fixed gantry techniques. Radiother Oncol. 2008;89:254–62.CrossRefPubMed
6.
go back to reference Park JM, Kim K, Chie EK, Choi CH, Ye SJ, Ha SW. RapidArc vs intensity-modulated radiation therapy for hepatocellular carcinoma: a comparative planning study. Br J Radiol. 2012;85:e323–9.CrossRefPubMedPubMedCentral Park JM, Kim K, Chie EK, Choi CH, Ye SJ, Ha SW. RapidArc vs intensity-modulated radiation therapy for hepatocellular carcinoma: a comparative planning study. Br J Radiol. 2012;85:e323–9.CrossRefPubMedPubMedCentral
7.
go back to reference Kim YS, Lee J, Park JI, Sung W, Lee SM, Kim GE. Volumetric modulated arc therapy for carotid sparing in the management of early glottic cancer. Radiat Oncol J. 2016;34:18–25.CrossRefPubMedPubMedCentral Kim YS, Lee J, Park JI, Sung W, Lee SM, Kim GE. Volumetric modulated arc therapy for carotid sparing in the management of early glottic cancer. Radiat Oncol J. 2016;34:18–25.CrossRefPubMedPubMedCentral
8.
go back to reference Ostheimer C, Hubsch P, Janich M, Gerlach R, Vordermark D. Dosimetric comparison of intensity-modulated radiotherapy (IMRT) and volumetric modulated arc therapy (VMAT) in total scalp irradiation: a single institutional experience. Radiat Oncol J. 2016;34:313–21.CrossRefPubMedPubMedCentral Ostheimer C, Hubsch P, Janich M, Gerlach R, Vordermark D. Dosimetric comparison of intensity-modulated radiotherapy (IMRT) and volumetric modulated arc therapy (VMAT) in total scalp irradiation: a single institutional experience. Radiat Oncol J. 2016;34:313–21.CrossRefPubMedPubMedCentral
9.
go back to reference Kataria T, Govardhan HB, Gupta D, Mohanraj U, Bisht SS, Sambasivaselli R, et al. Dosimetric comparison between volumetric modulated arc therapy (VMAT) vs intensity modulated radiation therapy (IMRT) for radiotherapy of mid esophageal carcinoma. J Cancer Res Ther. 2014;10:871–7.CrossRefPubMed Kataria T, Govardhan HB, Gupta D, Mohanraj U, Bisht SS, Sambasivaselli R, et al. Dosimetric comparison between volumetric modulated arc therapy (VMAT) vs intensity modulated radiation therapy (IMRT) for radiotherapy of mid esophageal carcinoma. J Cancer Res Ther. 2014;10:871–7.CrossRefPubMed
10.
go back to reference Mattes MD, Zhou Y, Berry SL, Barker CA. Dosimetric comparison of axilla and groin radiotherapy techniques for high-risk and locally advanced skin cancer. Radiat Oncol J. 2016;34:145–55.CrossRefPubMedPubMedCentral Mattes MD, Zhou Y, Berry SL, Barker CA. Dosimetric comparison of axilla and groin radiotherapy techniques for high-risk and locally advanced skin cancer. Radiat Oncol J. 2016;34:145–55.CrossRefPubMedPubMedCentral
11.
go back to reference Paik EK, Kim MS, Choi CW, Jang WI, Lee SH, Choi SH, et al. Dosimetric comparison of volumetric modulated arc therapy with robotic stereotactic radiation therapy in hepatocellular carcinoma. Radiat Oncol J. 2015;33:233–41.CrossRefPubMedPubMedCentral Paik EK, Kim MS, Choi CW, Jang WI, Lee SH, Choi SH, et al. Dosimetric comparison of volumetric modulated arc therapy with robotic stereotactic radiation therapy in hepatocellular carcinoma. Radiat Oncol J. 2015;33:233–41.CrossRefPubMedPubMedCentral
12.
go back to reference Treutwein M, Hipp M, Koelbl O, Dobler B. Searching standard parameters for volumetric modulated arc therapy (VMAT) of prostate cancer. Radiat Oncol. 2012;7:108.CrossRefPubMedPubMedCentral Treutwein M, Hipp M, Koelbl O, Dobler B. Searching standard parameters for volumetric modulated arc therapy (VMAT) of prostate cancer. Radiat Oncol. 2012;7:108.CrossRefPubMedPubMedCentral
14.
go back to reference de Boer J, Wolf AL, Szeto YZ, van Herk M, Sonke JJ. Dynamic collimator angle adjustments during volumetric modulated arc therapy to account for prostate rotations. Int J Radiat Oncol Biol Phys. 2015;91:1009–16.CrossRefPubMed de Boer J, Wolf AL, Szeto YZ, van Herk M, Sonke JJ. Dynamic collimator angle adjustments during volumetric modulated arc therapy to account for prostate rotations. Int J Radiat Oncol Biol Phys. 2015;91:1009–16.CrossRefPubMed
15.
go back to reference Zhang P, Happersett L, Yang Y, Yamada Y, Mageras G, Hunt M. Optimization of collimator trajectory in volumetric modulated arc therapy: development and evaluation for paraspinal SBRT. Int J Radiat Oncol Biol Phys. 2010;77:591–9.CrossRefPubMed Zhang P, Happersett L, Yang Y, Yamada Y, Mageras G, Hunt M. Optimization of collimator trajectory in volumetric modulated arc therapy: development and evaluation for paraspinal SBRT. Int J Radiat Oncol Biol Phys. 2010;77:591–9.CrossRefPubMed
16.
go back to reference Ahn BS, Park SY, Park JM, Choi CH, Chun M, Kim JI. Dosimetric effects of sectional adjustments of collimator angles on volumetric modulated arc therapy for irregularly-shaped targets. PLoS One. 2017;12:e0174924.CrossRefPubMedPubMedCentral Ahn BS, Park SY, Park JM, Choi CH, Chun M, Kim JI. Dosimetric effects of sectional adjustments of collimator angles on volumetric modulated arc therapy for irregularly-shaped targets. PLoS One. 2017;12:e0174924.CrossRefPubMedPubMedCentral
17.
go back to reference Park JM, Park SY, Ye SJ, Kim JH, Carlson J, Wu HG. New conformity indices based on the calculation of distances between the target volume and the volume of reference isodose. Br J Radiol. 2014;87:20140342.CrossRefPubMedPubMedCentral Park JM, Park SY, Ye SJ, Kim JH, Carlson J, Wu HG. New conformity indices based on the calculation of distances between the target volume and the volume of reference isodose. Br J Radiol. 2014;87:20140342.CrossRefPubMedPubMedCentral
18.
go back to reference Hodapp N. The ICRU report 83: prescribing, recording and reporting photon-beam intensity-modulated radiation therapy (IMRT). J ICRU. 2012;188:97–9. Hodapp N. The ICRU report 83: prescribing, recording and reporting photon-beam intensity-modulated radiation therapy (IMRT). J ICRU. 2012;188:97–9.
19.
go back to reference Park JM, Choi CH, Ha SW, Ye SJ. The dosimetric effect of mixed-energy IMRT plans for prostate cancer. J Appl Clin Med Phys. 2011;12:147–57.CrossRefPubMedCentral Park JM, Choi CH, Ha SW, Ye SJ. The dosimetric effect of mixed-energy IMRT plans for prostate cancer. J Appl Clin Med Phys. 2011;12:147–57.CrossRefPubMedCentral
20.
go back to reference Hall EJ, Wuu CS. Radiation-induced second cancers: the impact of 3D-CRT and IMRT. Int J Radiat Oncol Biol Phys. 2013;56:83–8.CrossRef Hall EJ, Wuu CS. Radiation-induced second cancers: the impact of 3D-CRT and IMRT. Int J Radiat Oncol Biol Phys. 2013;56:83–8.CrossRef
21.
go back to reference Yoon M, Ahn SH, Kim J, Shin DH, Park SY, Lee SB, et al. Radiation-induced cancers from modern radiotherapy techniques: intensity-modulated radiotherapy versus proton therapy. Int J Radiat Oncol. 2010;77:1477–85.CrossRef Yoon M, Ahn SH, Kim J, Shin DH, Park SY, Lee SB, et al. Radiation-induced cancers from modern radiotherapy techniques: intensity-modulated radiotherapy versus proton therapy. Int J Radiat Oncol. 2010;77:1477–85.CrossRef
22.
go back to reference Schneider U, Zwahlen D, Ross D, Kaser-Hotz B. Estimation of radiation-induced cancer from three-dimensional dose distributions: concept of organ equivalent dose. Int J Radiat Oncol. 2005;61:1510–5.CrossRef Schneider U, Zwahlen D, Ross D, Kaser-Hotz B. Estimation of radiation-induced cancer from three-dimensional dose distributions: concept of organ equivalent dose. Int J Radiat Oncol. 2005;61:1510–5.CrossRef
23.
go back to reference Paddick I. A simple scoring ratio to index the conformity of radiosurgical treatment plans. Technical note. J Neurosurg. 2000;93:219–22.PubMed Paddick I. A simple scoring ratio to index the conformity of radiosurgical treatment plans. Technical note. J Neurosurg. 2000;93:219–22.PubMed
24.
go back to reference Joseph PW, Schwartz D, Shao M, Osborn V, Choi K, Schreiber D. Stereotactic radiotherapy of the prostate: fractionation and utilization in the United States. Radiat Oncol J. 2017;35:137–43.CrossRef Joseph PW, Schwartz D, Shao M, Osborn V, Choi K, Schreiber D. Stereotactic radiotherapy of the prostate: fractionation and utilization in the United States. Radiat Oncol J. 2017;35:137–43.CrossRef
25.
go back to reference Bae SH, Kim DW, Kim MS, Shin MH, Park HC, Lim DH. Radiotherapy for gastric mucosa-associated lymphoid tissue lymphoma: dosimetric comparison and risk assessment of solid secondary cancer. Radiat Oncol J. 2017;35:78–89.CrossRefPubMedPubMedCentral Bae SH, Kim DW, Kim MS, Shin MH, Park HC, Lim DH. Radiotherapy for gastric mucosa-associated lymphoid tissue lymphoma: dosimetric comparison and risk assessment of solid secondary cancer. Radiat Oncol J. 2017;35:78–89.CrossRefPubMedPubMedCentral
26.
go back to reference Lee S, Kim J, Han S. A comparative review of radiation-induced Cancer risk models. J Radiat Prot Res. 2017;42(2):130–40.CrossRef Lee S, Kim J, Han S. A comparative review of radiation-induced Cancer risk models. J Radiat Prot Res. 2017;42(2):130–40.CrossRef
27.
go back to reference Oh Y, Kim DW, Shin DO, Koo J, Lee SS, Choi SH, et al. Comparative analysis of terminology and classification related to risk Management of Radiotherapy. Prog Med Phys. 2016;27(3):131–8.CrossRef Oh Y, Kim DW, Shin DO, Koo J, Lee SS, Choi SH, et al. Comparative analysis of terminology and classification related to risk Management of Radiotherapy. Prog Med Phys. 2016;27(3):131–8.CrossRef
28.
Metadata
Title
Optimal collimator rotation based on the outline of multiple brain targets in VMAT
Authors
Jung-in Kim
Beom Seok Ahn
Chang Heon Choi
Jong Min Park
So-Yeon Park
Publication date
01-12-2018
Publisher
BioMed Central
Published in
Radiation Oncology / Issue 1/2018
Electronic ISSN: 1748-717X
DOI
https://doi.org/10.1186/s13014-018-1039-5

Other articles of this Issue 1/2018

Radiation Oncology 1/2018 Go to the issue