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Journal of the International Society of Sports Nutrition
Published in: Journal of the International Society of Sports Nutrition 1/2018

Open Access 01-12-2018 | Review

Understanding the factors that effect maximal fat oxidation

Authors: Troy Purdom, Len Kravitz, Karol Dokladny, Christine Mermier

Published in: Journal of the International Society of Sports Nutrition | Issue 1/2018

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Abstract

Lipids as a fuel source for energy supply during submaximal exercise originate from subcutaneous adipose tissue derived fatty acids (FA), intramuscular triacylglycerides (IMTG), cholesterol and dietary fat. These sources of fat contribute to fatty acid oxidation (FAox) in various ways. The regulation and utilization of FAs in a maximal capacity occur primarily at exercise intensities between 45 and 65% VO2max, is known as maximal fat oxidation (MFO), and is measured in g/min. Fatty acid oxidation occurs during submaximal exercise intensities, but is also complimentary to carbohydrate oxidation (CHOox). Due to limitations within FA transport across the cell and mitochondrial membranes, FAox is limited at higher exercise intensities. The point at which FAox reaches maximum and begins to decline is referred to as the crossover point. Exercise intensities that exceed the crossover point (~65% VO2max) utilize CHO as the predominant fuel source for energy supply. Training status, exercise intensity, exercise duration, sex differences, and nutrition have all been shown to affect cellular expression responsible for FAox rate. Each stimulus affects the process of FAox differently, resulting in specific adaptions that influence endurance exercise performance. Endurance training, specifically long duration (>2 h) facilitate adaptations that alter both the origin of FAs and FAox rate. Additionally, the influence of sex and nutrition on FAox are discussed. Finally, the role of FAox in the improvement of performance during endurance training is discussed.
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Metadata
Title
Understanding the factors that effect maximal fat oxidation
Authors
Troy Purdom
Len Kravitz
Karol Dokladny
Christine Mermier
Publication date
01-12-2018
Publisher
BioMed Central
DOI
https://doi.org/10.1186/s12970-018-0207-1

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