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Journal of Cardiovascular Magnetic Resonance

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Open Access 01-12-2015 | Review

Normal values for cardiovascular magnetic resonance in adults and children

Authors: Nadine Kawel-Boehm, Alicia Maceira, Emanuela R Valsangiacomo-Buechel, Jens Vogel-Claussen, Evrim B Turkbey, Rupert Williams, Sven Plein, Michael Tee, John Eng, David A Bluemke

Published in: Journal of Cardiovascular Magnetic Resonance | Issue 1/2015

Abstract

Morphological and functional parameters such as chamber size and function, aortic diameters and distensibility, flow and T1 and T2* relaxation time can be assessed and quantified by cardiovascular magnetic resonance (CMR). Knowledge of normal values for quantitative CMR is crucial to interpretation of results and to distinguish normal from disease. In this review, we present normal reference values for morphological and functional CMR parameters of the cardiovascular system based on the peer-reviewed literature and current CMR techniques and sequences.

Harris RJ BM, Deeks JJ, Harbord RM, Altman DG, Sterne JAC. Metan: fixed- and random-effects meta-analysis. Stata J. 2008;8:3–28.

Selvin S. Statistical analysis of epidemiological data. 3rd ed. New York, USA: Oxford University Press; 2004.

Alfakih K, Plein S, Thiele H, Jones T, Ridgway JP, Sivananthan MU. Normal human left and right ventricular dimensions for MRI as assessed by turbo gradient echo and steady-state free precession imaging sequences. J Magn Reson Imaging. 2003;17:323–9.PubMed

Hudsmith LE, Petersen SE, Francis JM, Robson MD, Neubauer S. Normal human left and right ventricular and left atrial dimensions using steady state free precession magnetic resonance imaging. J Cardiovasc Magn Reson. 2005;7:775–82.PubMed

Maceira AM, Prasad SK, Khan M, Pennell DJ. Normalized left ventricular systolic and diastolic function by steady state free precession cardiovascular magnetic resonance. J Cardiovasc Magn Reson. 2006;8:417–26.PubMed

Vogel-Claussen J, Finn JP, Gomes AS, Hundley GW, Jerosch-Herold M, Pearson G, et al. Left ventricular papillary muscle mass: relationship to left ventricular mass and volumes by magnetic resonance imaging. J Comput Assist Tomogr. 2006;30:426–32.PubMed

Schulz-Menger J, Bluemke DA, Bremerich J, Flamm SD, Fogel MA, Friedrich MG, et al. Standardized image interpretation and post processing in cardiovascular magnetic resonance: Society for Cardiovascular Magnetic Resonance (SCMR) board of trustees task force on standardized post processing. J Cardiovasc Magn Reson. 2013;15:35.PubMedCentralPubMed

Reiter G, Reiter U, Rienmuller R, Gagarina N, Ryabikin A. On the value of geometry-based models for left ventricular volumetry in magnetic resonance imaging and electron beam tomography: a Bland-Altman analysis. Eur J Radiol. 2004;52:110–8.PubMed

Clay S, Alfakih K, Radjenovic A, Jones T, Ridgway JP, Sinvananthan MU. Normal range of human left ventricular volumes and mass using steady state free precession MRI in the radial long axis orientation. MAGMA. 2006;19:41–5.PubMed

10.

Cain PA, Ahl R, Hedstrom E, Ugander M, Allansdotter-Johnsson A, Friberg P, et al. Age and gender specific normal values of left ventricular mass, volume and function for gradient echo magnetic resonance imaging: a cross sectional study. BMC Med Imaging. 2009;9:2.PubMedCentralPubMed

11.

Natori S, Lai S, Finn JP, Gomes AS, Hundley WG, Jerosch-Herold M, et al. Cardiovascular function in multi-ethnic study of atherosclerosis: normal values by age, sex, and ethnicity. AJR Am J Roentgenol. 2006;186:S357–365.PubMed

12.

Salton CJ, Chuang ML, O'Donnell CJ, Kupka MJ, Larson MG, Kissinger KV, et al. Gender differences and normal left ventricular anatomy in an adult population free of hypertension. A cardiovascular magnetic resonance study of the Framingham Heart Study Offspring cohort. J Am Coll Cardiol. 2002;39:1055–60.PubMed

13.

Lorenz CH, Walker ES, Morgan VL, Klein SS, Graham Jr TP. Normal human right and left ventricular mass, systolic function, and gender differences by cine magnetic resonance imaging. J Cardiovasc Magn Reson. 1999;1:7–21.PubMed

14.

Sievers B, Kirchberg S, Bakan A, Franken U, Trappe HJ. Impact of papillary muscles in ventricular volume and ejection fraction assessment by cardiovascular magnetic resonance. J Cardiovasc Magn Reson. 2004;6:9–16.PubMed

15.

Winter MM, Bernink FJ, Groenink M, Bouma BJ, van Dijk AP, Helbing WA, et al. Evaluating the systemic right ventricle by CMR: the importance of consistent and reproducible delineation of the cavity. J Cardiovasc Magn Reson. 2008;10:40.PubMedCentralPubMed

16.

Maceira AM, Prasad SK, Khan M, Pennell DJ. Reference right ventricular systolic and diastolic function normalized to age, gender and body surface area from steady-state free precession cardiovascular magnetic resonance. Eur Heart J. 2006;27:2879–88.PubMed

17.

Maceira AM, Cosin-Sales J, Roughton M, Prasad SK, Pennell DJ. Reference left atrial dimensions and volumes by steady state free precession cardiovascular magnetic resonance. J Cardiovasc Magn Reson. 2010;12:65.PubMedCentralPubMed

18.

Sarikouch S, Koerperich H, Boethig D, Peters B, Lotz J, Gutberlet M, et al. Reference values for atrial size and function in children and young adults by cardiac MR: a study of the German competence network congenital heart defects. J Magn Reson Imaging. 2011;33:1028–39.PubMed

19.

Rohner A, Brinkert M, Kawel N, Buechel RR, Leibundgut G, Grize L, et al. Functional assessment of the left atrium by real-time three-dimensional echocardiography using a novel dedicated analysis tool: initial validation studies in comparison with computed tomography. Eur J Echocardiogr. 2011;12:497–505.PubMed

20.

Sievers B, Kirchberg S, Franken U, Bakan A, Addo M, John-Puthenveettil B, et al. Determination of normal gender-specific left atrial dimensions by cardiovascular magnetic resonance imaging. J Cardiovasc Magn Reson. 2005;7:677–83.PubMed

21.

Sievers B, Addo M, Breuckmann F, Barkhausen J, Erbel R. Reference right atrial function determined by steady-state free precession cardiovascular magnetic resonance. J Cardiovasc Magn Reson. 2007;9:807–14.PubMed

22.

Maceira AM, Cosin-Sales J, Roughton M, Prasad SK, Pennell DJ. Reference right atrial dimensions and volume estimation by steady state free precession cardiovascular magnetic resonance. J Cardiovasc Magn Reson. 2013;15:29.PubMedCentralPubMed

23.

Robbers-Visser D, Boersma E, Helbing WA. Normal biventricular function, volumes, and mass in children aged 8 to 17 years. J Magn Reson Imaging. 2009;29:552–9.PubMed

24.

Sarikouch S, Peters B, Gutberlet M, Leismann B, Kelter-Kloepping A, Koerperich H, et al. Sex-specific pediatric percentiles for ventricular size and mass as reference values for cardiac MRI: assessment by steady-state free-precession and phase-contrast MRI flow. Circ Cardiovasc Imaging. 2010;3:65–76.PubMed

25.

Buechel EV, Kaiser T, Jackson C, Schmitz A, Kellenberger CJ. Normal right- and left ventricular volumes and myocardial mass in children measured by steady state free precession cardiovascular magnetic resonance. J Cardiovasc Magn Reson. 2009;11:19.PubMedCentralPubMed

26.

Helbing WA, Rebergen SA, Maliepaard C, Hansen B, Ottenkamp J, Reiber JH, et al. Quantification of right ventricular function with magnetic resonance imaging in children with normal hearts and with congenital heart disease. Am Heart J. 1995;130:828–37.PubMed

27.

Lorenz CH. The range of normal values of cardiovascular structures in infants, children, and adolescents measured by magnetic resonance imaging. Pediatr Cardiol. 2000;21:37–46.PubMed

28.

Malayeri AA, Johnson WC, Macedo R, Bathon J, Lima JA, Bluemke DA. Cardiac cine MRI: Quantification of the relationship between fast gradient echo and steady-state free precession for determination of myocardial mass and volumes. J Magn Reson Imaging. 2008;28:60–6.PubMedCentralPubMed

29.

Kawel N, Turkbey EB, Carr JJ, Eng J, Gomes AS, Hundley WG, et al. Normal left ventricular myocardial thickness for middle-aged and older subjects with steady-state free precession cardiac magnetic resonance: the multi-ethnic study of atherosclerosis. Circ Cardiovasc Imaging. 2012;5:500–8.PubMedCentralPubMed

30.

Dawson DK, Maceira AM, Raj VJ, Graham C, Pennell DJ, Kilner PJ. Regional thicknesses and thickening of compacted and trabeculated myocardial layers of the normal left ventricle studied by cardiovascular magnetic resonance. Circ Cardiovasc Imaging. 2011;4:139–46.PubMedCentralPubMed

31.

Sondergaard L, Stahlberg F, Thomsen C, Spraggins TA, Gymoese E, Malmgren L, et al. Comparison between retrospective gating and ECG triggering in magnetic resonance velocity mapping. Magn Reson Imaging. 1993;11:533–7.PubMed

32.

Allen BD, Barker AJ, Carr JC, Silverberg RA, Markl M. Time-resolved three-dimensional phase contrast MRI evaluation of bicuspid aortic valve and coarctation of the aorta. Eur Heart J Cardiovasc Imaging. 2013;14:399.PubMedCentralPubMed

33.

Kupfahl C, Honold M, Meinhardt G, Vogelsberg H, Wagner A, Mahrholdt H, et al. Evaluation of aortic stenosis by cardiovascular magnetic resonance imaging: comparison with established routine clinical techniques. Heart. 2004;90:893–901.PubMedCentralPubMed

34.

Lotz J, Meier C, Leppert A, Galanski M. Cardiovascular flow measurement with phase-contrast MR imaging: basic facts and implementation. Radiographics. 2002;22:651–71.PubMed

35.

Srichai MB, Lim RP, Wong S, Lee VS. Cardiovascular applications of phase-contrast MRI. AJR Am J Roentgenol. 2009;192:662–75.PubMed

36.

Caruthers SD, Lin SJ, Brown P, Watkins MP, Williams TA, Lehr KA, et al. Practical value of cardiac magnetic resonance imaging for clinical quantification of aortic valve stenosis: comparison with echocardiography. Circulation. 2003;108:2236–43.

37.

Kilner PJ, Manzara CC, Mohiaddin RH, Pennell DJ, Sutton MG, Firmin DN, et al. Magnetic resonance jet velocity mapping in mitral and aortic valve stenosis. Circulation. 1993;87:1239–48.PubMed

38.

Myerson SG. Heart valve disease: investigation by cardiovascular magnetic resonance. J Cardiovasc Magn Reson. 2012;14:7.PubMedCentralPubMed

39.

Bonow RO, Carabello BA, Chatterjee K, de Leon Jr AC, Faxon DP, Freed MD, et al. 2008 Focused update incorporated into the ACC/AHA 2006 guidelines for the management of patients with valvular heart disease: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 1998 Guidelines for the Management of Patients With Valvular Heart Disease): endorsed by the Society of Cardiovascular Anesthesiologists, Society for Cardiovascular Angiography and Interventions, and Society of Thoracic Surgeons. Circulation. 2008;118:e523–661.PubMed

40.

Bonow RO, Carabello BA, Kanu C, de Leon Jr AC, Faxon DP, Freed MD, et al. ACC/AHA 2006 guidelines for the management of patients with valvular heart disease: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (writing committee to revise the 1998 Guidelines for the Management of Patients With Valvular Heart Disease): developed in collaboration with the Society of Cardiovascular Anesthesiologists: endorsed by the Society for Cardiovascular Angiography and Interventions and the Society of Thoracic Surgeons. Circulation. 2006;114:e84–231.PubMed

41.

Manning WJ, Pennell DJ. Cardiovascular magnetic resonance. In: Book Cardiovascular magnetic resonance. 2nd ed. Philadelphia, USA: Saunders/Elsevier; 2010.

42.

Rathi VK, Doyle M, Yamrozik J, Williams RB, Caruppannan K, Truman C, et al. Routine evaluation of left ventricular diastolic function by cardiovascular magnetic resonance: a practical approach. J Cardiovasc Magn Reson. 2008;10:36.PubMedCentralPubMed

43.

Caudron J, Fares J, Bauer F, Dacher JN. Evaluation of left ventricular diastolic function with cardiac MR imaging. Radiographics. 2011;31:239–59.PubMed

44.

Potthast S, Mitsumori L, Stanescu LA, Richardson ML, Branch K, Dubinsky TJ, et al. Measuring aortic diameter with different MR techniques: comparison of three-dimensional (3D) navigated steady-state free-precession (SSFP), 3D contrast-enhanced magnetic resonance angiography (CE-MRA), 2D T2 black blood, and 2D cine SSFP. J Magn Reson Imaging. 2010;31:177–84.PubMed

45.

Turkbey EB, Jain A, Johnson C, Redheuil A, Arai AE, Gomes AS, et al. Determinants and normal values of ascending aortic diameter by age, gender, and race/ethnicity in the Multi-Ethnic Study of Atherosclerosis (MESA). J Magn Reson Imaging. 2014;39:360–8.PubMedCentralPubMed

46.

Davis AE, Lewandowski AJ, Holloway CJ, Ntusi NA, Banerjee R, Nethononda R, et al. Observational study of regional aortic size referenced to body size: production of a cardiovascular magnetic resonance nomogram. J Cardiovasc Magn Reson. 2014;16:9.PubMedCentralPubMed

47.

Burman ED, Keegan J, Kilner PJ. Aortic root measurement by cardiovascular magnetic resonance: specification of planes and lines of measurement and corresponding normal values. Circ Cardiovasc Imaging. 2008;1:104–13.PubMed

48.

Redheuil A, Yu WC, Mousseaux E, Harouni AA, Kachenoura N, Wu CO, et al. Age-related changes in aortic arch geometry: relationship with proximal aortic function and left ventricular mass and remodeling. J Am Coll Cardiol. 2011;58:1262–70.PubMedCentralPubMed

49.

Sugawara J, Hayashi K, Yokoi T, Tanaka H. Age-associated elongation of the ascending aorta in adults. JACC Cardiovasc Imaging. 2008;1:739–48.PubMed

50.

Lederle FA, Johnson GR, Wilson SE, Chute EP, Littooy FN, Bandyk D, et al. Prevalence and associations of abdominal aortic aneurysm detected through screening. Aneurysm Detection and Management (ADAM) Veterans Affairs Cooperative Study Group. Ann Intern Med. 1997;126:441–9.PubMed

51.

Redheuil A, Yu WC, Wu CO, Mousseaux E, de Cesare A, Yan R, et al. Reduced ascending aortic strain and distensibility: earliest manifestations of vascular aging in humans. Hypertension. 2010;55:319–26.PubMedCentralPubMed

52.

Kaiser T, Kellenberger CJ, Albisetti M, Bergstrasser E, Valsangiacomo Buechel ER. Normal values for aortic diameters in children and adolescents–assessment in vivo by contrast-enhanced CMR-angiography. J Cardiovasc Magn Reson. 2008;10:56.PubMedCentralPubMed

53.

Voges I, Jerosch-Herold M, Hedderich J, Pardun E, Hart C, Gabbert DD, et al. Normal values of aortic dimensions, distensibility, and pulse wave velocity in children and young adults: a cross-sectional study. J Cardiovasc Magn Reson. 2012;14:77.PubMedCentralPubMed

54.

Kutty S, Kuehne T, Gribben P, Reed E, Li L, Danford DA, et al. Ascending aortic and main pulmonary artery areas derived from cardiovascular magnetic resonance as reference values for normal subjects and repaired tetralogy of Fallot. Circ Cardiovasc Imaging. 2012;5:644–51.PubMed

55.

Dogui A, Redheuil A, Lefort M, DeCesare A, Kachenoura N, Herment A, et al. Measurement of aortic arch pulse wave velocity in cardiovascular MR: comparison of transit time estimators and description of a new approach. J Magn Reson Imaging. 2011;33:1321–9.PubMed

56.

Turkbey EB, Redheuil A, Backlund JY, Small AC, Cleary PA, Lachin JM, et al. Complications Trial/Epidemiology of Diabetes I, Complications Research G: Aortic distensibility in type 1 diabetes. Diabetes Care. 2013;36:2380–7.PubMedCentralPubMed

57.

Cavalcante JL, Lima JA, Redheuil A, Al-Mallah MH. Aortic stiffness: current understanding and future directions. J Am Coll Cardiol. 2011;57:1511–22.PubMed

58.

Rose JL, Lalande A, Bouchot O, el Bourennane B, Walker PM, Ugolini P, et al. Influence of age and sex on aortic distensibility assessed by MRI in healthy subjects. Magn Reson Imaging. 2010;28:255–63.PubMed

59.

Messroghli DR, Radjenovic A, Kozerke S, Higgins DM, Sivananthan MU, Ridgway JP. Modified Look-Locker inversion recovery (MOLLI) for high-resolution T1 mapping of the heart. Magn Reson Med. 2004;52:141–6.PubMed

60.

Piechnik SK, Ferreira VM, Dall'Armellina E, Cochlin LE, Greiser A, Neubauer S, et al. Shortened Modified Look-Locker Inversion recovery (ShMOLLI) for clinical myocardial T1-mapping at 1.5 and 3T within a 9 heartbeat breathhold. J Cardiovasc Magn Reson. 2010;12:69.PubMedCentralPubMed

61.

Chow K, Flewitt JA, Green JD, Pagano JJ, Friedrich MG, Thompson RB. Saturation recovery single-shot acquisition (SASHA) for myocardial T(1) mapping. Magn Reson Med. 2014;71:2082–95.PubMed

62.

Kawel N, Nacif M, Zavodni A, Jones J, Liu S, Sibley CT, et al. T1 mapping of the myocardium: intra-individual assessment of the effect of field strength, cardiac cycle and variation by myocardial region. J Cardiovasc Magn Reson. 2012;14:27.PubMedCentralPubMed

63.

Schelbert EB, Testa SM, Meier CG, Ceyrolles WJ, Levenson JE, Blair AJ, et al. Myocardial extravascular extracellular volume fraction measurement by gadolinium cardiovascular magnetic resonance in humans: slow infusion versus bolus. J Cardiovasc Magn Reson. 2011;13:16.PubMedCentralPubMed

64.

Gai N, Turkbey EB, Nazarian S, van der Geest RJ, Liu CY, Lima JA, et al. T1 mapping of the gadolinium-enhanced myocardium: adjustment for factors affecting interpatient comparison. Magn Reson Med. 2011;65:1407–15.PubMedCentralPubMed

65.

Kawel N, Nacif M, Zavodni A, Jones J, Liu S, Sibley CT, et al. T1 mapping of the myocardium: intra-individual assessment of post-contrast T1 time evolution and extracellular volume fraction at 3T for Gd-DTPA and Gd-BOPTA. J Cardiovasc Magn Reson. 2012;14:26.PubMedCentralPubMed

66.

Lee JJ, Liu S, Nacif MS, Ugander M, Han J, Kawel N, et al. Myocardial T1 and extracellular volume fraction mapping at 3 tesla. J Cardiovasc Magn Reson. 2011;13:75.PubMedCentralPubMed

67.

Puntmann VO, D'Cruz D, Smith Z, Pastor A, Choong P, Voigt T, et al. Native myocardial T1 mapping by cardiovascular magnetic resonance imaging in subclinical cardiomyopathy in patients with systemic lupus erythematosus. Circ Cardiovasc Imaging. 2013;6:295–301.PubMed

68.

Ugander M, Oki AJ, Hsu LY, Kellman P, Greiser A, Aletras AH, et al. Extracellular volume imaging by magnetic resonance imaging provides insights into overt and sub-clinical myocardial pathology. Eur Heart J. 2012;33:1268–78.PubMedCentralPubMed

69.

Flett AS, Sado DM, Quarta G, Mirabel M, Pellerin D, Herrey AS, et al. Diffuse myocardial fibrosis in severe aortic stenosis: an equilibrium contrast cardiovascular magnetic resonance study. Eur Heart J Cardiovasc Imaging. 2012;13:819–26.PubMed

70.

Sado DM, Flett AS, Banypersad SM, White SK, Maestrini V, Quarta G, et al. Cardiovascular magnetic resonance measurement of myocardial extracellular volume in health and disease. Heart. 2012;98:1436–41.PubMed

71.

White SK, Sado DM, Flett AS, Moon JC. Characterising the myocardial interstitial space: the clinical relevance of non-invasive imaging. Heart. 2012;98:773–9.PubMed

72.

Arheden H, Saeed M, Higgins CB, Gao DW, Ursell PC, Bremerich J, et al. Reperfused rat myocardium subjected to various durations of ischemia: estimation of the distribution volume of contrast material with echo-planar MR imaging. Radiology. 2000;215:520–8.PubMed

73.

Kellman P, Wilson JR, Xue H, Ugander M, Arai AE. Extracellular volume fraction mapping in the myocardium, part 1: evaluation of an automated method. J Cardiovasc Magn Reson. 2012;14:63.PubMedCentralPubMed

74.

Piechnik SK, Ferreira VM, Lewandowski AJ, Ntusi NA, Banerjee R, Holloway C, et al. Normal variation of magnetic resonance T1 relaxation times in the human population at 1.5T using ShMOLLI. J Cardiovasc Magn Reson. 2013;15:13.PubMedCentralPubMed

75.

Bull S, White SK, Piechnik SK, Flett AS, Ferreira VM, Loudon M, et al. Human non-contrast T1 values and correlation with histology in diffuse fibrosis. Heart. 2013;99:932–7.PubMedCentralPubMed

76.

Fontana M, White SK, Banypersad SM, Sado DM, Maestrini V, Flett AS, et al. Comparison of T1 mapping techniques for ECV quantification. Histological validation and reproducibility of ShMOLLI versus multibreath-hold T1 quantification equilibrium contrast CMR. J Cardiovasc Magn Reson. 2012;14:88.PubMedCentralPubMed

77.

Iles L, Pfluger H, Phrommintikul A, Cherayath J, Aksit P, Gupta SN, et al. Evaluation of diffuse myocardial fibrosis in heart failure with cardiac magnetic resonance contrast-enhanced T1 mapping. J Am Coll Cardiol. 2008;52:1574–80.PubMed

78.

Kellman P, Wilson JR, Xue H, Bandettini WP, Shanbhag SM, Druey KM, et al. Extracellular volume fraction mapping in the myocardium, part 2: initial clinical experience. J Cardiovasc Magn Reson. 2012;14:64.PubMedCentralPubMed

79.

Puntmann VO, Voigt T, Chen Z, Mayr M, Karim R, Rhode K, et al. Native T1 mapping in differentiation of normal myocardium from diffuse disease in hypertrophic and dilated cardiomyopathy. JACC Cardiovasc Imaging. 2013;6:475–84.PubMed

80.

Liu S, Han J, Nacif MS, Jones J, Kawel N, Kellman P, et al. Diffuse myocardial fibrosis evaluation using cardiac magnetic resonance T1 mapping: sample size considerations for clinical trials. J Cardiovasc Magn Reson. 2012;14:90.PubMedCentralPubMed

81.

Pennell DJ. T2* magnetic resonance: iron and gold. JACC Cardiovasc Imaging. 2008;1:579–81.PubMed

82.

Anderson LJ, Holden S, Davis B, Prescott E, Charrier CC, Bunce NH, et al. Cardiovascular T2-star (T2*) magnetic resonance for the early diagnosis of myocardial iron overload. Eur Heart J. 2001;22:2171–9.PubMed

83.

Wood JC, Ghugre N. Magnetic resonance imaging assessment of excess iron in thalassemia, sickle cell disease and other iron overload diseases. Hemoglobin. 2008;32:85–96.PubMedCentralPubMed

84.

Pennell DJ, Udelson JE, Arai AE, Bozkurt B, Cohen AR, Galanello R, et al. Cardiovascular function and treatment in beta-thalassemia major: a consensus statement from the American Heart Association. Circulation. 2013;128:281–308.PubMed

85.

Kirk P, Smith GC, Roughton M, He T, Pennell DJ. Myocardial T2* is not affected by ageing, myocardial fibrosis, or impaired left ventricular function. J Magn Reson Imaging. 2010;32:1095–8.PubMed

86.

Pepe A, Positano V, Santarelli MF, Sorrentino F, Cracolici E, De Marchi D, et al. Multislice multiecho T2* cardiovascular magnetic resonance for detection of the heterogeneous distribution of myocardial iron overload. J Magn Reson Imaging. 2006;23:662–8.PubMed

87.

Kirk P, Roughton M, Porter JB, Walker JM, Tanner MA, Patel J, et al. Cardiac T2* magnetic resonance for prediction of cardiac complications in thalassemia major. Circulation. 2009;120:1961–8.PubMedCentralPubMed

88.

Arts T, Prinzen FW, Delhaas T, Milles JR, Rossi AC, Clarysse P. Mapping displacement and deformation of the heart with local sine-wave modeling. IEEE Trans Med Imaging. 2010;29:1114–23.PubMed

89.

Cupps BP, Taggar AK, Reynolds LM, Lawton JS, Pasque MK. Regional myocardial contractile function: multiparametric strain mapping. Interact Cardiovasc Thorac Surg. 2010;10:953–7.PubMedCentralPubMed

90.

Del-Canto I, Lopez-Lereu MP, Monmeneu JV, Croisille P, Clarysse P, Chorro FJ, et al. Characterization of normal regional myocardial function by MRI cardiac tagging. J Magn Reson Imaging. 2015;41:83–92.PubMed

91.

el Ibrahim SH. Myocardial tagging by cardiovascular magnetic resonance: evolution of techniques–pulse sequences, analysis algorithms, and applications. J Cardiovasc Magn Reson. 2011;13:36.PubMedCentral

92.

Miller CA, Borg A, Clark D, Steadman CD, McCann GP, Clarysse P, et al. Comparison of local sine wave modeling with harmonic phase analysis for the assessment of myocardial strain. J Magn Reson Imaging. 2013;38:320–8.PubMed

93.

Bogaert J, Rademakers FE. Regional nonuniformity of normal adult human left ventricle. Am J Physiol Heart Circ Physiol. 2001;280:H610–620.PubMed

94.

Jeung MY, Germain P, Croisille P, El Ghannudi S, Roy C, Gangi A. Myocardial tagging with MR imaging: overview of normal and pathologic findings. Radiographics. 2012;32:1381–98.PubMed

95.

Piella G, De Craene M, Bijnens BH, Tobon-Gomez C, Huguet M, Avegliano G, et al. Characterizing myocardial deformation in patients with left ventricular hypertrophy of different etiologies using the strain distribution obtained by magnetic resonance imaging. Rev Esp Cardiol. 2010;63:1281–91.PubMed

96.

Young AA, Kramer CM, Ferrari VA, Axel L, Reichek N. Three-dimensional left ventricular deformation in hypertrophic cardiomyopathy. Circulation. 1994;90:854–67.PubMed

97.

Castillo E, Osman NF, Rosen BD, El-Shehaby I, Pan L, Jerosch-Herold M, et al. Quantitative assessment of regional myocardial function with MR-tagging in a multi-center study: interobserver and intraobserver agreement of fast strain analysis with Harmonic Phase (HARP) MRI. J Cardiovasc Magn Reson. 2005;7:783–91.PubMed

98.

Moore CC, Lugo-Olivieri CH, McVeigh ER, Zerhouni EA. Three-dimensional systolic strain patterns in the normal human left ventricle: characterization with tagged MR imaging. Radiology. 2000;214:453–66.PubMedCentralPubMed

99.

Augustine D, Lewandowski AJ, Lazdam M, Rai A, Francis J, Myerson S, et al. Global and regional left ventricular myocardial deformation measures by magnetic resonance feature tracking in healthy volunteers: comparison with tagging and relevance of gender. J Cardiovasc Magn Reson. 2013;15:8.PubMedCentralPubMed

100.

Oxenham HC, Young AA, Cowan BR, Gentles TL, Occleshaw CJ, Fonseca CG, et al. Age-related changes in myocardial relaxation using three-dimensional tagged magnetic resonance imaging. J Cardiovasc Magn Reson. 2003;5:421–30.PubMed

101.

Lawton JS, Cupps BP, Knutsen AK, Ma N, Brady BD, Reynolds LM, et al. Magnetic resonance imaging detects significant sex differences in human myocardial strain. Biomed Eng Oxnline. 2011;10:76.

102.

Shehata ML, Cheng S, Osman NF, Bluemke DA, Lima JA. Myocardial tissue tagging with cardiovascular magnetic resonance. J Cardiovasc Magn Reson. 2009;11:55.PubMedCentralPubMed

103.

Venkatesh BA, Donekal S, Yoneyama K, Wu C, Fernandes VR, Rosen BD, et al: Regional myocardial functional patterns: Quantitative tagged magnetic resonance imaging in an adult population free of cardiovascular risk factors: The multi-ethnic study of atherosclerosis (MESA). J Magn Reson Imaging 2014 [Epub ahead of print].

104.

Kuijer JP, Marcus JT, Gotte MJ, van Rossum AC, Heethaar RM. Three-dimensional myocardial strains at end-systole and during diastole in the left ventricle of normal humans. J Cardiovasc Magn Reson. 2002;4:341–51.PubMed

Title: Normal values for cardiovascular magnetic resonance in adults and children
Authors: Nadine Kawel-Boehm
Alicia Maceira
Emanuela R Valsangiacomo-Buechel
Jens Vogel-Claussen
Evrim B Turkbey
Rupert Williams
Sven Plein
Michael Tee
John Eng
David A Bluemke
Publication date: 01-12-2015
Publisher: BioMed Central
Published in: Journal of Cardiovascular Magnetic Resonance / Issue 1/2015
Electronic ISSN: 1532-429X
DOI: https://doi.org/10.1186/s12968-015-0111-7

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Normal values for cardiovascular magnetic resonance in adults and children

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