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Published in: Journal of Translational Medicine 1/2022

Open Access 01-12-2022 | Cryotherapy | Research

Combination of whole body cryotherapy with static stretching exercises reduces fatigue and improves functioning of the autonomic nervous system in Chronic Fatigue Syndrome

Authors: Sławomir Kujawski, Joanna Słomko, Beata R. Godlewska, Agnieszka Cudnoch-Jędrzejewska, Modra Murovska, Julia L. Newton, Łukasz Sokołowski, Paweł Zalewski

Published in: Journal of Translational Medicine | Issue 1/2022

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Abstract

Background

The aim of this study was to explore the tolerability and effect of static stretching (SS) and whole body cryotherapy (WBC) upon fatigue, daytime sleepiness, cognitive functioning and objective and subjective autonomic nervous system functioning in those with Chronic Fatigue Syndrome (CFS) compared to a control population.

Methods

Thirty-two CFS and eighteen healthy controls (HC) participated in 2 weeks of a SS + WBC programme. This programme was composed of five sessions per week, 10 sessions in total.

Results

A significant decrease in fatigue was noted in the CFS group in response to SS + WBC. Some domains of cognitive functioning (speed of processing visual information and set-shifting) also improved in response to SS + WBC in both CFS and HC groups. Our study has confirmed that WBC is well tolerated by those with CFS and leads to symptomatic improvements associated with changes in cardiovascular and autonomic function.

Conclusions

Given the preliminary data showing the beneficial effect of cryotherapy, its relative ease of application, good tolerability, and proven safety, therapy with cold exposure appears to be an approach worth attention. Further studies of cryotherapy as a potential treatment in CFS is important in the light of the lack of effective therapeutic options for these common and often disabling symptoms.
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Literature
1.
go back to reference Estévez-López F, Mudie K, Wang-Steverding X, Bakken IJ, Ivanovs A, Castro-Marrero J, Nacul L, Alegre J, Zalewski P, Słomko J, Strand EB. Systematic Review of the Epidemiological Burden of Myalgic encephalomyelitis/chronic fatigue syndrome across Europe: current evidence and EUROMENE research recommendations for epidemiology. J Clin Med. 2002;9(5):1557.CrossRef Estévez-López F, Mudie K, Wang-Steverding X, Bakken IJ, Ivanovs A, Castro-Marrero J, Nacul L, Alegre J, Zalewski P, Słomko J, Strand EB. Systematic Review of the Epidemiological Burden of Myalgic encephalomyelitis/chronic fatigue syndrome across Europe: current evidence and EUROMENE research recommendations for epidemiology. J Clin Med. 2002;9(5):1557.CrossRef
2.
go back to reference Słomko J, Newton JL, Kujawski S, Tafil-Klawe M, Klawe J, Staines D, Marshall-Gradisnik S, Zalewski P. Prevalence and characteristics of chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) in Poland: a cross-sectional study. BMJ Open. 2019;9(3): e023955.PubMedPubMedCentralCrossRef Słomko J, Newton JL, Kujawski S, Tafil-Klawe M, Klawe J, Staines D, Marshall-Gradisnik S, Zalewski P. Prevalence and characteristics of chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) in Poland: a cross-sectional study. BMJ Open. 2019;9(3): e023955.PubMedPubMedCentralCrossRef
3.
go back to reference Nelson MJ, Bahl JS, Buckley JD, Thomson RL, Davison K. Evidence of altered cardiac autonomic regulation in myalgic encephalomyelitis/chronic fatigue syndrome: a systematic review and meta-analysis. Medicine. 2019;98(43): e17600.PubMedPubMedCentralCrossRef Nelson MJ, Bahl JS, Buckley JD, Thomson RL, Davison K. Evidence of altered cardiac autonomic regulation in myalgic encephalomyelitis/chronic fatigue syndrome: a systematic review and meta-analysis. Medicine. 2019;98(43): e17600.PubMedPubMedCentralCrossRef
4.
go back to reference Laborde S, Mosley E, Thayer JF. Heart rate variability and cardiac vagal tone in psychophysiological research–recommendations for experiment planning, data analysis, and data reporting. Front Psychol. 2017;8:213.PubMedPubMedCentralCrossRef Laborde S, Mosley E, Thayer JF. Heart rate variability and cardiac vagal tone in psychophysiological research–recommendations for experiment planning, data analysis, and data reporting. Front Psychol. 2017;8:213.PubMedPubMedCentralCrossRef
5.
go back to reference Perna G, Riva A, Defillo A, Sangiorgio E, Nobile M, Caldirola D. Heart rate variability: Can it serve as a marker of mental health resilience?: Special Section on “Translational and Neuroscience Studies in Affective Disorders” Section Editor, Maria Nobile MD, PhD. J Affect Disord. 2020;263:754–61.PubMedCrossRef Perna G, Riva A, Defillo A, Sangiorgio E, Nobile M, Caldirola D. Heart rate variability: Can it serve as a marker of mental health resilience?: Special Section on “Translational and Neuroscience Studies in Affective Disorders” Section Editor, Maria Nobile MD, PhD. J Affect Disord. 2020;263:754–61.PubMedCrossRef
6.
go back to reference Institute of Medicine (US), Committee on the Diagnostic Criteria for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome. Beyond Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Redefining an Illness; National Academies Press: Cambridge, MA, USA, (2015) Institute of Medicine (US), Committee on the Diagnostic Criteria for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome. Beyond Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Redefining an Illness; National Academies Press: Cambridge, MA, USA, (2015)
7.
go back to reference Logsdon RG, Gibbons LE, McCurry SM, Teri L. Assessing quality of life in older adults with cognitive impairment. Psychosom Med. 2002;64:510–9.PubMedCrossRef Logsdon RG, Gibbons LE, McCurry SM, Teri L. Assessing quality of life in older adults with cognitive impairment. Psychosom Med. 2002;64:510–9.PubMedCrossRef
9.
go back to reference Robinson LJ, Gallagher P, Watson S, Pearce R, Finkelmeyer A, Maclachlan L, Newton JL. Impairments in cognitive performance in chronic fatigue syndrome are common, not related to co-morbid depression but do associate with autonomic dysfunction. PLoS ONE. 2019;14(2): e0210394.PubMedPubMedCentralCrossRef Robinson LJ, Gallagher P, Watson S, Pearce R, Finkelmeyer A, Maclachlan L, Newton JL. Impairments in cognitive performance in chronic fatigue syndrome are common, not related to co-morbid depression but do associate with autonomic dysfunction. PLoS ONE. 2019;14(2): e0210394.PubMedPubMedCentralCrossRef
10.
go back to reference Cockshell SJ, Mathias JL. Cognitive deficits in chronic fatigue syndrome and their relationship to psychological status, symptomatology, and everyday functioning. Neuropsychology. 2013;27(2):230.PubMedCrossRef Cockshell SJ, Mathias JL. Cognitive deficits in chronic fatigue syndrome and their relationship to psychological status, symptomatology, and everyday functioning. Neuropsychology. 2013;27(2):230.PubMedCrossRef
11.
go back to reference DeLuca J, Johnson SK, Ellis SP, Natelson BH. Cognitive functioning is impaired in patients with chronic fatigue syndrome devoid of psychiatric disease. J Neurol Neurosurg Psychiatry. 1997;1997(62):151–5.CrossRef DeLuca J, Johnson SK, Ellis SP, Natelson BH. Cognitive functioning is impaired in patients with chronic fatigue syndrome devoid of psychiatric disease. J Neurol Neurosurg Psychiatry. 1997;1997(62):151–5.CrossRef
13.
go back to reference Westerlund T, Smolander J, Uusitalo-Koskinen A, Mikkelsson M. The blood pressure responses to an acute and long-term whole-body cryotherapy (− 110 C) in men and women. J Therm Biol. 2004;29(6):285–90.CrossRef Westerlund T, Smolander J, Uusitalo-Koskinen A, Mikkelsson M. The blood pressure responses to an acute and long-term whole-body cryotherapy (− 110 C) in men and women. J Therm Biol. 2004;29(6):285–90.CrossRef
15.
go back to reference Kujawski S, Newton JL, Morten KJ, Zalewski P. Whole-body cryostimulation application with age: a review. J Therm Biol. 2021;96:102861.PubMedCrossRef Kujawski S, Newton JL, Morten KJ, Zalewski P. Whole-body cryostimulation application with age: a review. J Therm Biol. 2021;96:102861.PubMedCrossRef
16.
go back to reference Zalewski P, Klawe JJ, Pawlak J, Tafil-Klawe M, Newton J. Thermal and hemodynamic response to whole-body cryostimulation in healthy subjects. Cryobiology. 2013;66(3):295–302.PubMedCrossRef Zalewski P, Klawe JJ, Pawlak J, Tafil-Klawe M, Newton J. Thermal and hemodynamic response to whole-body cryostimulation in healthy subjects. Cryobiology. 2013;66(3):295–302.PubMedCrossRef
17.
go back to reference Zalewski P, Buszko K, Zawadka-Kunikowska M, Słomko J, Szrajda J, Klawe JJ, Tafil-Klawe M, Sinski M, Newton J. Cardiovascular and autonomic responses to whole-body cryostimulation in essential hypertension. Cryobiology. 2014;69(2):249–55.PubMedCrossRef Zalewski P, Buszko K, Zawadka-Kunikowska M, Słomko J, Szrajda J, Klawe JJ, Tafil-Klawe M, Sinski M, Newton J. Cardiovascular and autonomic responses to whole-body cryostimulation in essential hypertension. Cryobiology. 2014;69(2):249–55.PubMedCrossRef
18.
go back to reference Zalewski P, Bitner A, Słomko J, Szrajda J, Klawe JJ, Tafil-Klawe M, Newton JL. Whole-body cryostimulation increases parasympathetic outflow and decreases core body temperature. J Therm Biol. 2014;45:75–80.PubMedCrossRef Zalewski P, Bitner A, Słomko J, Szrajda J, Klawe JJ, Tafil-Klawe M, Newton JL. Whole-body cryostimulation increases parasympathetic outflow and decreases core body temperature. J Therm Biol. 2014;45:75–80.PubMedCrossRef
20.
go back to reference Mourot L, Cluzeau C, Regnard J. Physiological assessment of a gaseous cryotherapy device thermal effects and changes in cardiovascular autonomic control. Ann Readapt Med Phys. 2007;50:2209–17. Mourot L, Cluzeau C, Regnard J. Physiological assessment of a gaseous cryotherapy device thermal effects and changes in cardiovascular autonomic control. Ann Readapt Med Phys. 2007;50:2209–17.
21.
go back to reference Kujawski S, Bach AM, Słomko J, Pheby DF, Murovska M, Newton JL, Zalewski P. Changes in the allostatic response to whole-body cryotherapy and static-stretching exercises in chronic fatigue syndrome patients vs. healthy individuals. J Clin Med. 2021;10(13):2795.PubMedPubMedCentralCrossRef Kujawski S, Bach AM, Słomko J, Pheby DF, Murovska M, Newton JL, Zalewski P. Changes in the allostatic response to whole-body cryotherapy and static-stretching exercises in chronic fatigue syndrome patients vs. healthy individuals. J Clin Med. 2021;10(13):2795.PubMedPubMedCentralCrossRef
22.
go back to reference Vitenet M, Tubez F, Marreiro A, Polidori G, Taiar R, Legrand F, Boyer FC. Effect of whole body cryotherapy interventions on health-related quality of life in fibromyalgia patients: a randomized controlled trial. Complement Ther Med. 2018;36:6–8.PubMedCrossRef Vitenet M, Tubez F, Marreiro A, Polidori G, Taiar R, Legrand F, Boyer FC. Effect of whole body cryotherapy interventions on health-related quality of life in fibromyalgia patients: a randomized controlled trial. Complement Ther Med. 2018;36:6–8.PubMedCrossRef
23.
go back to reference Pournot H, Bieuzen F, Louis J, Mounier R, Fillard JR, Barbiche E, et al. Time-course of changes in inflammatory response after whole-body cryotherapy multi exposures following severe exercise. PLoS ONE. 2011;6: e22748.PubMedPubMedCentralCrossRef Pournot H, Bieuzen F, Louis J, Mounier R, Fillard JR, Barbiche E, et al. Time-course of changes in inflammatory response after whole-body cryotherapy multi exposures following severe exercise. PLoS ONE. 2011;6: e22748.PubMedPubMedCentralCrossRef
24.
go back to reference Schaal K, Meur YLE, Louis J, Filliard JR, Hellard P, Casazza G, et al. Whole-body cryostimulation limits overreaching in elite synchronized swimmers. Med Sci Sports Exerc. 2015;47:1416–25.PubMedCrossRef Schaal K, Meur YLE, Louis J, Filliard JR, Hellard P, Casazza G, et al. Whole-body cryostimulation limits overreaching in elite synchronized swimmers. Med Sci Sports Exerc. 2015;47:1416–25.PubMedCrossRef
25.
go back to reference Carpenter JS, Robillard R, Hermens DF, Naismith SL, Gordon C, Scott EM, Hickie IB. Sleep-wake profiles and circadian rhythms of core temperature and melatonin in young people with affective disorders. J Psychiatr Res. 2017;94:131–8.PubMedCrossRef Carpenter JS, Robillard R, Hermens DF, Naismith SL, Gordon C, Scott EM, Hickie IB. Sleep-wake profiles and circadian rhythms of core temperature and melatonin in young people with affective disorders. J Psychiatr Res. 2017;94:131–8.PubMedCrossRef
26.
go back to reference Cambras T, Castro-Marrero J, Zaragoza MC, Díez-Noguera A, Alegre J. Circadian rhythm abnormalities and autonomic dysfunction in patients with Chronic Fatigue Syndrome/Myalgic Encephalomyelitis. PLoS ONE. 2018;13(6): e0198106.PubMedPubMedCentralCrossRef Cambras T, Castro-Marrero J, Zaragoza MC, Díez-Noguera A, Alegre J. Circadian rhythm abnormalities and autonomic dysfunction in patients with Chronic Fatigue Syndrome/Myalgic Encephalomyelitis. PLoS ONE. 2018;13(6): e0198106.PubMedPubMedCentralCrossRef
27.
go back to reference Dupuy O, Douzi W, Theurot D, Bosquet L, Dugué B. An evidence-based approach for choosing post-exercise recovery techniques to reduce markers of muscle damage, soreness, fatigue, and inflammation: a systematic review with meta-analysis. Front Physiol. 2018;9:403.PubMedPubMedCentralCrossRef Dupuy O, Douzi W, Theurot D, Bosquet L, Dugué B. An evidence-based approach for choosing post-exercise recovery techniques to reduce markers of muscle damage, soreness, fatigue, and inflammation: a systematic review with meta-analysis. Front Physiol. 2018;9:403.PubMedPubMedCentralCrossRef
28.
go back to reference Rymaszewska J, Lion KM, Stańczykiewicz B, Rymaszewska JE, Trypka E, Pawlik-Sobecka L, Kokot I, Płaczkowska S, Zabłocka A, Szcześniak D. The improvement of cognitive deficits after whole-body cryotherapy—a randomised controlled trial. Exp Gerontol. 2021;146:111237.PubMedCrossRef Rymaszewska J, Lion KM, Stańczykiewicz B, Rymaszewska JE, Trypka E, Pawlik-Sobecka L, Kokot I, Płaczkowska S, Zabłocka A, Szcześniak D. The improvement of cognitive deficits after whole-body cryotherapy—a randomised controlled trial. Exp Gerontol. 2021;146:111237.PubMedCrossRef
29.
go back to reference Lempke LB, Fraser JJ, Erdman NK, Barone NA, Saliba S, Resch JE. The effects of cranial cryotherapy on hemodynamics and cognition in healthy adults. Transl J ACSM. 2020;2020(5):1–9. Lempke LB, Fraser JJ, Erdman NK, Barone NA, Saliba S, Resch JE. The effects of cranial cryotherapy on hemodynamics and cognition in healthy adults. Transl J ACSM. 2020;2020(5):1–9.
30.
go back to reference Okura Y, Rikimaru T. Cold stimuli on the cheeks activate the left ventrolateral prefrontal cortex and enhance cognitive performance. J Cogn Enhanc. 2020;5(2):164–75.CrossRef Okura Y, Rikimaru T. Cold stimuli on the cheeks activate the left ventrolateral prefrontal cortex and enhance cognitive performance. J Cogn Enhanc. 2020;5(2):164–75.CrossRef
31.
go back to reference Theurot D, Dugué B, Douzi W, Guitet P, Louis J, Dupuy O. Impact of acute partial-body cryostimulation on cognitive performance, cerebral oxygenation, and cardiac autonomic activity. Sci Rep. 2021;11(1):7793.PubMedPubMedCentralCrossRef Theurot D, Dugué B, Douzi W, Guitet P, Louis J, Dupuy O. Impact of acute partial-body cryostimulation on cognitive performance, cerebral oxygenation, and cardiac autonomic activity. Sci Rep. 2021;11(1):7793.PubMedPubMedCentralCrossRef
33.
go back to reference Jung W, Jang KI, Lee SH. Heart and brain interaction of psychiatric illness: a review focused on heart rate variability, cognitive function, and quantitative electroencephalography. Clin Psychopharmacol Neurosci. 2019;17(4):459–74.PubMedPubMedCentralCrossRef Jung W, Jang KI, Lee SH. Heart and brain interaction of psychiatric illness: a review focused on heart rate variability, cognitive function, and quantitative electroencephalography. Clin Psychopharmacol Neurosci. 2019;17(4):459–74.PubMedPubMedCentralCrossRef
34.
go back to reference McCaffrey RJ, Duff K, Westervelt HJ. Practitioner’s guide to evaluating change with neuropsychological assessment instruments. New York: Kluwer Academic/Plenum Publishers; 2000.CrossRef McCaffrey RJ, Duff K, Westervelt HJ. Practitioner’s guide to evaluating change with neuropsychological assessment instruments. New York: Kluwer Academic/Plenum Publishers; 2000.CrossRef
35.
go back to reference McCaffrey RJ, Westervelt HJ. Issues associated with repeated neuropsychological assessments. Neuropsychol Rev. 1995;5:203–21.PubMedCrossRef McCaffrey RJ, Westervelt HJ. Issues associated with repeated neuropsychological assessments. Neuropsychol Rev. 1995;5:203–21.PubMedCrossRef
36.
go back to reference Pilcher JJ, Nadler E, Busch C. Effects of hot and cold temperature exposure on performance: a meta-analytic review. Ergonomics. 2002;45(10):682–98.PubMedCrossRef Pilcher JJ, Nadler E, Busch C. Effects of hot and cold temperature exposure on performance: a meta-analytic review. Ergonomics. 2002;45(10):682–98.PubMedCrossRef
37.
go back to reference Muller MD, Gunstad J, Alosco ML, Miller LA, Updegraff J, Spitznagel MB, Glickman E. Acute cold exposure and cognitive function: evidence for sustained impairment. Ergonomics. 2012;55(7):792–8.PubMedPubMedCentralCrossRef Muller MD, Gunstad J, Alosco ML, Miller LA, Updegraff J, Spitznagel MB, Glickman E. Acute cold exposure and cognitive function: evidence for sustained impairment. Ergonomics. 2012;55(7):792–8.PubMedPubMedCentralCrossRef
38.
go back to reference Solianik R, Skurvydas A, Mickevičienė D, Brazaitis M. Intermittent whole-body cold immersion induces similar thermal stress but different motor and cognitive responses between males and females. Cryobiology. 2014;69(2):323–32.PubMedCrossRef Solianik R, Skurvydas A, Mickevičienė D, Brazaitis M. Intermittent whole-body cold immersion induces similar thermal stress but different motor and cognitive responses between males and females. Cryobiology. 2014;69(2):323–32.PubMedCrossRef
39.
go back to reference Hausswirth C, Louis J, Bieuzen F, Pournot H, Fournier J, Filliard JR, Brisswalter J. Effects of whole-body cryotherapy vs. far-infrared vs. passive modalities on recovery from exercise-induced muscle damage in highly-trained runners. PLoS ONE. 2011;6(12):e27749.PubMedPubMedCentralCrossRef Hausswirth C, Louis J, Bieuzen F, Pournot H, Fournier J, Filliard JR, Brisswalter J. Effects of whole-body cryotherapy vs. far-infrared vs. passive modalities on recovery from exercise-induced muscle damage in highly-trained runners. PLoS ONE. 2011;6(12):e27749.PubMedPubMedCentralCrossRef
40.
go back to reference Patil PG, Apfelbaum JL, Zacny JP. Effects of a cold-water stressor on psychomotor and cognitive functioning in humans. Physiol Behav. 1995;58:1281–6.PubMedCrossRef Patil PG, Apfelbaum JL, Zacny JP. Effects of a cold-water stressor on psychomotor and cognitive functioning in humans. Physiol Behav. 1995;58:1281–6.PubMedCrossRef
41.
go back to reference Klintberg IH, Larsson ME. Shall we use cryotherapy in the treatment in surgical procedures, in acute pain or injury, or in long term pain or dysfunction? A systematic review. J Bodyw Mov Ther. 2021;27:368–87.PubMedCrossRef Klintberg IH, Larsson ME. Shall we use cryotherapy in the treatment in surgical procedures, in acute pain or injury, or in long term pain or dysfunction? A systematic review. J Bodyw Mov Ther. 2021;27:368–87.PubMedCrossRef
42.
go back to reference Zalewski P, Kujawski S, Tudorowska M, Morten K, Tafil-Klawe M, Klawe JJ, Strong J, Estévez-López F, Murovska M, Newton JL. The impact of a structured exercise programme upon cognitive function in chronic fatigue syndrome patients. Brain Sci. 2020;10(1):4.CrossRef Zalewski P, Kujawski S, Tudorowska M, Morten K, Tafil-Klawe M, Klawe JJ, Strong J, Estévez-López F, Murovska M, Newton JL. The impact of a structured exercise programme upon cognitive function in chronic fatigue syndrome patients. Brain Sci. 2020;10(1):4.CrossRef
43.
go back to reference Kujawski S, Cossington J, Słomko J, Dawes H, Strong JW, Estevez-Lopez F, Murovska M, Newton JL, Hodges L, Zalewski P. Prediction of discontinuation of structured exercise programme in chronic fatigue syndrome patients. J Clin Med. 2020;9(11):3436.PubMedCentralCrossRef Kujawski S, Cossington J, Słomko J, Dawes H, Strong JW, Estevez-Lopez F, Murovska M, Newton JL, Hodges L, Zalewski P. Prediction of discontinuation of structured exercise programme in chronic fatigue syndrome patients. J Clin Med. 2020;9(11):3436.PubMedCentralCrossRef
44.
go back to reference Westerlund T, Uusitalo A, Smolander J, Mikkelsson M. Heart rate variability in women exposed to very cold air (− 110 C) during whole-body cryotherapy. J Therm Biol. 2006;31(4):342–6.CrossRef Westerlund T, Uusitalo A, Smolander J, Mikkelsson M. Heart rate variability in women exposed to very cold air (− 110 C) during whole-body cryotherapy. J Therm Biol. 2006;31(4):342–6.CrossRef
45.
go back to reference Huttunen P, Rintamäki H, Hirvonen J. Effect of regular winter swimming on the activity of the sympathoadrenal system before and after a single cold water immersion. Int J Circumpol Health. 2001;60:400–6.CrossRef Huttunen P, Rintamäki H, Hirvonen J. Effect of regular winter swimming on the activity of the sympathoadrenal system before and after a single cold water immersion. Int J Circumpol Health. 2001;60:400–6.CrossRef
46.
go back to reference Hausswirth C, Schaal K, Le Meur Y, Bieuzen F, Filliard JR, Volondat M, et al. Parasympathetic activity and blood catecholamine responses following a single partial-body cryostimulation and a whole-body cryostimulation. PLoS ONE. 2013;8: e72658.PubMedPubMedCentralCrossRef Hausswirth C, Schaal K, Le Meur Y, Bieuzen F, Filliard JR, Volondat M, et al. Parasympathetic activity and blood catecholamine responses following a single partial-body cryostimulation and a whole-body cryostimulation. PLoS ONE. 2013;8: e72658.PubMedPubMedCentralCrossRef
47.
go back to reference Goldstein, David S. Principles of autonomic medicine. (2017) Goldstein, David S. Principles of autonomic medicine. (2017)
48.
go back to reference Graham TE, Sathasivam PR, MacNaughton KW. Influence of cold, exercise, and caffeine on catecholamines and metabolism in men. J Appl Physiol. 1991;70(5):2052–8.PubMedCrossRef Graham TE, Sathasivam PR, MacNaughton KW. Influence of cold, exercise, and caffeine on catecholamines and metabolism in men. J Appl Physiol. 1991;70(5):2052–8.PubMedCrossRef
49.
go back to reference Douzi W, Dupuy O, Theurot D, Smolander J, Dugué B. Per-cooling (Using cooling systems during physical exercise) enhances physical and cognitive performances in hot environments: a narrative review. Int J Environ Res Public Health. 2020;17(3):1031.PubMedCentralCrossRef Douzi W, Dupuy O, Theurot D, Smolander J, Dugué B. Per-cooling (Using cooling systems during physical exercise) enhances physical and cognitive performances in hot environments: a narrative review. Int J Environ Res Public Health. 2020;17(3):1031.PubMedCentralCrossRef
50.
go back to reference Bongers CC, Hopman MT, Eijsvogels TM. Cooling interventions for athletes: an overview of effectiveness, physiological mechanisms, and practical considerations. Temperature. 2017;4(1):60–78.CrossRef Bongers CC, Hopman MT, Eijsvogels TM. Cooling interventions for athletes: an overview of effectiveness, physiological mechanisms, and practical considerations. Temperature. 2017;4(1):60–78.CrossRef
51.
go back to reference Mawhinney C, Low DA, Jones H, Green DJ, Costello JT, Gregson W. Cold-water mediates greater reductions in limb blood flow than whole body cryotherapy. Med Sci Sports Exerc. 2017;49(6):1252–60.PubMedCrossRef Mawhinney C, Low DA, Jones H, Green DJ, Costello JT, Gregson W. Cold-water mediates greater reductions in limb blood flow than whole body cryotherapy. Med Sci Sports Exerc. 2017;49(6):1252–60.PubMedCrossRef
52.
go back to reference Hohenauer E, Deliens T, Clarys P, Clijsen R. Perfusion of the skin’s microcirculation after cold-water immersion (10 C) and partial-body cryotherapy (− 135 C). Skin Res Technol. 2019;25(5):677–82.PubMedPubMedCentralCrossRef Hohenauer E, Deliens T, Clarys P, Clijsen R. Perfusion of the skin’s microcirculation after cold-water immersion (10 C) and partial-body cryotherapy (− 135 C). Skin Res Technol. 2019;25(5):677–82.PubMedPubMedCentralCrossRef
53.
go back to reference Costello JT, Culligan K, Selfe J, Donnelly AE. Muscle, skin and core temperature after− 110 C cold air and 8 C water treatment. PLoS ONE. 2012;7(11): e48190.PubMedPubMedCentralCrossRef Costello JT, Culligan K, Selfe J, Donnelly AE. Muscle, skin and core temperature after− 110 C cold air and 8 C water treatment. PLoS ONE. 2012;7(11): e48190.PubMedPubMedCentralCrossRef
55.
go back to reference Wegmann M, Faude O, Poppendieck W, Hecksteden A, Fröhlich M, Meyer T. Pre-cooling and sports performance. Sports Med. 2012;42(7):545–64.PubMedCrossRef Wegmann M, Faude O, Poppendieck W, Hecksteden A, Fröhlich M, Meyer T. Pre-cooling and sports performance. Sports Med. 2012;42(7):545–64.PubMedCrossRef
56.
go back to reference Reilly T, Drust B, Gregson W. Thermoregulation in elite athletes. Curr Opin Clin Nutr Metab Care. 2017;2006(9):666–71. Reilly T, Drust B, Gregson W. Thermoregulation in elite athletes. Curr Opin Clin Nutr Metab Care. 2017;2006(9):666–71.
57.
go back to reference Daniel RM, Danson MJ, Eisenthal R, Lee CK, Peterson ME. The effect of temperature on enzyme activity: new insights and their implications. Extremophiles. 2008;12(1):51–9.PubMedCrossRef Daniel RM, Danson MJ, Eisenthal R, Lee CK, Peterson ME. The effect of temperature on enzyme activity: new insights and their implications. Extremophiles. 2008;12(1):51–9.PubMedCrossRef
58.
go back to reference James CA, Richardson AJ, Watt PW, Gibson OR, Maxwell NS. Physiological responses to incremental exercise in the heat following internal and external precooling. Scand J Med Sci Sports. 2015;25:190–9.PubMedCrossRef James CA, Richardson AJ, Watt PW, Gibson OR, Maxwell NS. Physiological responses to incremental exercise in the heat following internal and external precooling. Scand J Med Sci Sports. 2015;25:190–9.PubMedCrossRef
59.
go back to reference Olschewski H, Bruck K. Thermoregulatory, cardiovascular, and muscular factors related to exercise after precooling. J Appl Physiol. 1985;1988(64):803–11. Olschewski H, Bruck K. Thermoregulatory, cardiovascular, and muscular factors related to exercise after precooling. J Appl Physiol. 1985;1988(64):803–11.
60.
go back to reference Schmidt V, Bruck K. Effect of a precooling maneuver on body temperature and exercise performance. J Appl Physiol Respir Environ Exerc Physiol. 1981;50:772–8.PubMed Schmidt V, Bruck K. Effect of a precooling maneuver on body temperature and exercise performance. J Appl Physiol Respir Environ Exerc Physiol. 1981;50:772–8.PubMed
61.
go back to reference Leeder J, Gissane C, van Someren K, Gregson W, Howatson G. Cold water immersion and recovery from strenuous exercise: a meta-analysis. Br J Sports Med. 2012;46:233–40.PubMedCrossRef Leeder J, Gissane C, van Someren K, Gregson W, Howatson G. Cold water immersion and recovery from strenuous exercise: a meta-analysis. Br J Sports Med. 2012;46:233–40.PubMedCrossRef
62.
go back to reference Ascensão A, Leite M, Rebelo AN, Magalhäes S, Magalhäes J. Effects of cold water immersion on the recovery of physical performance and muscle damage following a one-off soccer match. J Sports Sci. 2011;29:217–25.PubMedCrossRef Ascensão A, Leite M, Rebelo AN, Magalhäes S, Magalhäes J. Effects of cold water immersion on the recovery of physical performance and muscle damage following a one-off soccer match. J Sports Sci. 2011;29:217–25.PubMedCrossRef
64.
go back to reference Herrera E, Sandoval MC, Camargo DM, Salvini TF. Effect of walking and resting after three cryotherapy modalities on the recovery of sensory and motor nerve conduction velocity in healthy subjects. Rev Bras Fisioter. 2011;15:233–40.PubMedCrossRef Herrera E, Sandoval MC, Camargo DM, Salvini TF. Effect of walking and resting after three cryotherapy modalities on the recovery of sensory and motor nerve conduction velocity in healthy subjects. Rev Bras Fisioter. 2011;15:233–40.PubMedCrossRef
65.
66.
go back to reference Negendank WI, Shaller CA. Temperature-dependence of ATP level, organic phosphate production and Na, K-ATPase in human lymphocytes. Physiol Chem Phys. 1982;14(6):513–8.PubMed Negendank WI, Shaller CA. Temperature-dependence of ATP level, organic phosphate production and Na, K-ATPase in human lymphocytes. Physiol Chem Phys. 1982;14(6):513–8.PubMed
67.
go back to reference Senczyszyn A, Wallner R, Szczesniak DM, Łuc M, Rymaszewska J. The effectiveness of computerized cognitive training combined with whole body cryotherapy in improving cognitive functions in older adults. A case control study. Front Psychiatry. 2021;12:1048.CrossRef Senczyszyn A, Wallner R, Szczesniak DM, Łuc M, Rymaszewska J. The effectiveness of computerized cognitive training combined with whole body cryotherapy in improving cognitive functions in older adults. A case control study. Front Psychiatry. 2021;12:1048.CrossRef
68.
go back to reference Fukuda K, Straus SE, Hickie I, Sharpe MC, Dobbins JG, Komaroff A, International Chronic Fatigue Syndrome Study Group. The chronic fatigue syndrome: a comprehensive approach to its definition and study. Ann Intern Med. 1994;121(12):953–9.PubMedCrossRef Fukuda K, Straus SE, Hickie I, Sharpe MC, Dobbins JG, Komaroff A, International Chronic Fatigue Syndrome Study Group. The chronic fatigue syndrome: a comprehensive approach to its definition and study. Ann Intern Med. 1994;121(12):953–9.PubMedCrossRef
69.
go back to reference Kujawski S, Cossington J, Słomko J, Zawadka-Kunikowska M, Tafil-Klawe M, Klawe JJ, Buszko K, Jakovljevic DG, Kozakiewicz M, Morten KJ, Dawes H. Relationship between cardiopulmonary, mitochondrial and autonomic nervous system function improvement after an individualised activity programme upon chronic fatigue syndrome patients. J Clin Med. 2021;10(7):1542.PubMedPubMedCentralCrossRef Kujawski S, Cossington J, Słomko J, Zawadka-Kunikowska M, Tafil-Klawe M, Klawe JJ, Buszko K, Jakovljevic DG, Kozakiewicz M, Morten KJ, Dawes H. Relationship between cardiopulmonary, mitochondrial and autonomic nervous system function improvement after an individualised activity programme upon chronic fatigue syndrome patients. J Clin Med. 2021;10(7):1542.PubMedPubMedCentralCrossRef
70.
go back to reference Zmijewski P, Lipinska P, Czajkowska A, Mróz A, Kapuściński P, Mazurek K. Acute effects of a static vs. a dynamic stretching warm-up on repeated-sprint performance in female handball players. J Hum Kinet. 2020;72(1):161–72.PubMedPubMedCentralCrossRef Zmijewski P, Lipinska P, Czajkowska A, Mróz A, Kapuściński P, Mazurek K. Acute effects of a static vs. a dynamic stretching warm-up on repeated-sprint performance in female handball players. J Hum Kinet. 2020;72(1):161–72.PubMedPubMedCentralCrossRef
71.
72.
go back to reference Fisk JD, Ritvo PG, Ross L, Haase DA, Marrie TJ, Schlech WF. Measuring the functional impact of fatigue: initial validation of the fatigue impact scale. Clin Infect Dis. 1994;18(Supplement_1):S79–83.PubMedCrossRef Fisk JD, Ritvo PG, Ross L, Haase DA, Marrie TJ, Schlech WF. Measuring the functional impact of fatigue: initial validation of the fatigue impact scale. Clin Infect Dis. 1994;18(Supplement_1):S79–83.PubMedCrossRef
73.
go back to reference Krupp LB, LaRocca NG, Muir-Nash J, Steinberg AD. The fatigue severity scale: application to patients with multiple sclerosis and systemic lupus erythematosus. Arch Neurol. 1989;46(10):1121–3.PubMedCrossRef Krupp LB, LaRocca NG, Muir-Nash J, Steinberg AD. The fatigue severity scale: application to patients with multiple sclerosis and systemic lupus erythematosus. Arch Neurol. 1989;46(10):1121–3.PubMedCrossRef
74.
go back to reference Johns MW. A new method for measuring daytime sleepiness: the Epworth sleepiness scale. Sleep. 1991;14(6):540–5.PubMedCrossRef Johns MW. A new method for measuring daytime sleepiness: the Epworth sleepiness scale. Sleep. 1991;14(6):540–5.PubMedCrossRef
75.
go back to reference Reitan RM. Validity of the Trail Making Test as an indicator of organic brain damage. Percept Mot Skills. 1958;8:271–6.CrossRef Reitan RM. Validity of the Trail Making Test as an indicator of organic brain damage. Percept Mot Skills. 1958;8:271–6.CrossRef
76.
go back to reference Crowe SF. The differential contribution of mental tracking, cognitive flexibility, visual search, and motor speed to performance on parts A and B of the Trail Making Test. J Clin Psychol. 1998;54:585–91.PubMedCrossRef Crowe SF. The differential contribution of mental tracking, cognitive flexibility, visual search, and motor speed to performance on parts A and B of the Trail Making Test. J Clin Psychol. 1998;54:585–91.PubMedCrossRef
77.
go back to reference Arbuthnott K, Frank J. Trail making test, part B as a measure of executive control: validation using a set-switching paradigm. J Clin Exp Neuropsychol. 2000;22:518–28.PubMedCrossRef Arbuthnott K, Frank J. Trail making test, part B as a measure of executive control: validation using a set-switching paradigm. J Clin Exp Neuropsychol. 2000;22:518–28.PubMedCrossRef
78.
go back to reference Kortte KB, Horner MD, Windham WK. The trail making test, part B:cognitive flexibility or ability to maintain set? Appl Neuropsychol. 2002;9:106–9.PubMedCrossRef Kortte KB, Horner MD, Windham WK. The trail making test, part B:cognitive flexibility or ability to maintain set? Appl Neuropsychol. 2002;9:106–9.PubMedCrossRef
79.
go back to reference Lezak MD, Howieson DB, Loring DW. Neuropsychological assessment. New York: Oxford University Press; 2004. p. 368–70. Lezak MD, Howieson DB, Loring DW. Neuropsychological assessment. New York: Oxford University Press; 2004. p. 368–70.
80.
go back to reference Jaeger J. Digit symbol substitution test: the case for sensitivity over specificity in neuropsychological testing. J Clin Psychopharmacol. 2018;38(5):513.PubMedPubMedCentralCrossRef Jaeger J. Digit symbol substitution test: the case for sensitivity over specificity in neuropsychological testing. J Clin Psychopharmacol. 2018;38(5):513.PubMedPubMedCentralCrossRef
81.
go back to reference Suarez GA, Opfer-Gehrking TL, Offord KP, et al. The autonomic symptom profile: a new instrument to assess autonomic symptoms. Neurology. 1999;52:523–8.PubMedCrossRef Suarez GA, Opfer-Gehrking TL, Offord KP, et al. The autonomic symptom profile: a new instrument to assess autonomic symptoms. Neurology. 1999;52:523–8.PubMedCrossRef
82.
83.
go back to reference Kim HA, Lee H, Park KJ, Lim JG. Autonomic dysfunction in patients with orthostatic dizziness: validation of orthostatic grading scale and comparison of Valsalva maneuver. J Neurol Sci. 2013;325(1–2):61–6.PubMedCrossRef Kim HA, Lee H, Park KJ, Lim JG. Autonomic dysfunction in patients with orthostatic dizziness: validation of orthostatic grading scale and comparison of Valsalva maneuver. J Neurol Sci. 2013;325(1–2):61–6.PubMedCrossRef
84.
go back to reference Fortin, J., Klinger, T., Wagner, C., Sterner, H., Madritsch, C., Grullenberger, R. The task force monitor – a non-invasive beat-to-beat monitor for hemodynamic and autonomic function of the human body. Proceedings of the 20th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, Austin, TX. (1998). Fortin, J., Klinger, T., Wagner, C., Sterner, H., Madritsch, C., Grullenberger, R. The task force monitor – a non-invasive beat-to-beat monitor for hemodynamic and autonomic function of the human body. Proceedings of the 20th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, Austin, TX. (1998).
85.
go back to reference Bates D, Mächler M, Bolker BM, Walker SC. Fitting linear mixed-effects models using lme4. J Stat Softw. 2015;67:1–48.CrossRef Bates D, Mächler M, Bolker BM, Walker SC. Fitting linear mixed-effects models using lme4. J Stat Softw. 2015;67:1–48.CrossRef
86.
go back to reference Fox J, Weisberg S. An R companion to applied regression. 3rd ed. Thousand Oaks: Sage; 2019. Fox J, Weisberg S. An R companion to applied regression. 3rd ed. Thousand Oaks: Sage; 2019.
87.
go back to reference Luke SG. Evaluating significance in linear mixed-effects models in R. Behav Res Methods. 2017;49(4):1494–502.PubMedCrossRef Luke SG. Evaluating significance in linear mixed-effects models in R. Behav Res Methods. 2017;49(4):1494–502.PubMedCrossRef
88.
go back to reference Lenth RV. Least-squares means: The R Package lsmeans. J Stat Softw. 2016;69:1–33.CrossRef Lenth RV. Least-squares means: The R Package lsmeans. J Stat Softw. 2016;69:1–33.CrossRef
Metadata
Title
Combination of whole body cryotherapy with static stretching exercises reduces fatigue and improves functioning of the autonomic nervous system in Chronic Fatigue Syndrome
Authors
Sławomir Kujawski
Joanna Słomko
Beata R. Godlewska
Agnieszka Cudnoch-Jędrzejewska
Modra Murovska
Julia L. Newton
Łukasz Sokołowski
Paweł Zalewski
Publication date
01-12-2022
Publisher
BioMed Central
Published in
Journal of Translational Medicine / Issue 1/2022
Electronic ISSN: 1479-5876
DOI
https://doi.org/10.1186/s12967-022-03460-1

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