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World Journal of Surgical Oncology
Published in: World Journal of Surgical Oncology 1/2018

Open Access 01-12-2018 | Case report

Dedifferentiated liposarcoma of the gallbladder: first reported case

Authors: Adriano Carneiro da Costa, Fernando Santa-Cruz, Brena F. Sena, Ademar Lopes, Nicole Leite, Alexandre Rolim da Paz, Álvaro A. B. Ferraz, José-Luiz Figueiredo

Published in: World Journal of Surgical Oncology | Issue 1/2018

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Abstract

Background

Liposarcoma of the gallbladder is an extremely rare sarcoma, with only five cases reported in the literature according to our knowledge.

Case presentation

A 71-year-old woman was referred to the Surgical Oncology Division of Napoleão Laureano Hospital (João Pessoa, PB, Brazil) due to a solid mass at the right side of the abdomen and fever, with no signs of jaundice. Abdominal ultrasonography and computed tomography (CT) evidenced an extensive gallbladder lobular formation adhered to the inferior border of the right hepatic lobe and cholelithiasis. The CT report suggested gallbladder liposarcoma. A cholecystectomy associated with resection of segments IV-B and V of the liver were performed. Intraoperative frozen sections were compatible with gallbladder sarcoma. Anatomopathological examination and immunohistochemistry confirmed dedifferentiated liposarcoma with foci of heterologous leiomyosarcomatous differentiation and undifferentiated fusocellular areas of high histological grade.

Conclusion

This is the first case of dedifferentiated liposarcoma of the gallbladder to be reported.
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Metadata
Title
Dedifferentiated liposarcoma of the gallbladder: first reported case
Authors
Adriano Carneiro da Costa
Fernando Santa-Cruz
Brena F. Sena
Ademar Lopes
Nicole Leite
Alexandre Rolim da Paz
Álvaro A. B. Ferraz
José-Luiz Figueiredo
Publication date
01-12-2018
Publisher
BioMed Central
Published in
World Journal of Surgical Oncology / Issue 1/2018
Electronic ISSN: 1477-7819
DOI
https://doi.org/10.1186/s12957-018-1520-5

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