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Published in: World Journal of Surgical Oncology 1/2018

Open Access 01-12-2018 | Research

Is ERAS effective and safe in laparoscopic gastrectomy for gastric carcinoma? A meta-analysis

Authors: Ming-zhe Li, Wen-hui Wu, Liang Li, Xue-fu Zhou, Heng-liang Zhu, Jian-feng Li, Yu-long He

Published in: World Journal of Surgical Oncology | Issue 1/2018

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Abstract

Background

It is still unclear whether enhanced recovery after surgery is effective and safe in laparoscopic gastrectomy for gastric carcinoma.

Methods

Cochrane library databases, Medline, Embase, and Pubmed were searched from January 1, 1986, to December 31, 2016. Randomized controlled trials (RCTs) comparing fast-track recovery with conventional recovery strategies in laparoscopic radical gastrectomy for gastric carcinoma were included. The main outcomes measured were postoperative hospital stay, time to first flatus, hospital charge, and overall complication rate.

Results

Six RCTs with 400 patients were included in this study. Fast-track surgery has shorter postoperative hospital stays (weighted mean difference (WMD) − 2.65; 95% CI, − 4.01 to − 1.29, z = 3.82, P < 0.01) and less hospitalization expenditure (WMD − 523.43; 95% CI, − 799.79 to − 247.06, z = 3.71, P < 0.01) than conventional recovery strategies. There was no significant difference with respect to duration to first flatus (WMD − 17.72; 95% CI, − 39.46–4.02, z = 1.60, P = 0.11) and complication rate (OR 1.57; 95% CI, 0.82–2.98, z = 1.37, P = 0.17).

Conclusions

Enhanced recovery after surgery is effective and safe and is thus recommended in laparoscopic radical gastrectomy for gastric carcinoma.
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Metadata
Title
Is ERAS effective and safe in laparoscopic gastrectomy for gastric carcinoma? A meta-analysis
Authors
Ming-zhe Li
Wen-hui Wu
Liang Li
Xue-fu Zhou
Heng-liang Zhu
Jian-feng Li
Yu-long He
Publication date
01-12-2018
Publisher
BioMed Central
Published in
World Journal of Surgical Oncology / Issue 1/2018
Electronic ISSN: 1477-7819
DOI
https://doi.org/10.1186/s12957-018-1309-6

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