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Published in: World Journal of Surgical Oncology 1/2017

Open Access 01-12-2017 | Research

Postoperative functional status in patients with supratentorial superficial low-grade glioma

Authors: Ji Zhang, Yin sheng Chen, You-ping Li, Zheng-quan Zhu, Jian-min Liu, Cheng-cheng Guo, Qun-ying Yang, Xiao-li Wang, Ying-hua Rao, Qing Mao, Wen-yan Li, Lu Ma, Yun qiang Yang, Shi-yin Xiao

Published in: World Journal of Surgical Oncology | Issue 1/2017

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Abstract

Background

We investigated the functional status of adult supratentorial superficial low-grade glioma (ASS-LGG) after surgery and analyzed its relevant factors to guide the therapeutic strategy and improve the life quality of these patients.

Methods

Clinical materials from January 2008 to December 2010 in 104 adults with ASS-LGG were analyzed retrospectively. The follow-up period ranged from 6 months to 1.5 years. The logistic regression was used to evaluate the preoperative and postoperative variation of functional status in patients to disclose the relevant factors affecting postoperative functional status, such as age, gender, the duration of symptom, size and location of the tumor, hemisphere, resection degree, and tumor pathologic grade and preoperative Karnofsky performance status (Pre-KPS).

Results

Four out of nine candidate factors are related to the postoperative functional status. They are age less than 40 years, the size of tumor less than 5 cm in diameter, tumor located in the right hemisphere, and limited resection of tumor in the eloquent area.

Conclusions

It seems more meaningful to evaluate the functional status of the patients with ASS-LGG on the basis of these clinical features, involving age, tumor size, location, and extent of resection.
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Metadata
Title
Postoperative functional status in patients with supratentorial superficial low-grade glioma
Authors
Ji Zhang
Yin sheng Chen
You-ping Li
Zheng-quan Zhu
Jian-min Liu
Cheng-cheng Guo
Qun-ying Yang
Xiao-li Wang
Ying-hua Rao
Qing Mao
Wen-yan Li
Lu Ma
Yun qiang Yang
Shi-yin Xiao
Publication date
01-12-2017
Publisher
BioMed Central
Published in
World Journal of Surgical Oncology / Issue 1/2017
Electronic ISSN: 1477-7819
DOI
https://doi.org/10.1186/s12957-017-1237-x

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