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Published in: World Journal of Surgical Oncology 1/2017

Open Access 01-12-2017 | Case Report

Colorectal cancer in a patient with intestinal schistosomiasis: a case report from Kilimanjaro Christian Medical Center Northern Zone Tanzania

Authors: Ayesiga M Herman, Alfred Kishe, Heri Babu, Hilary Shilanaiman, Murad Tarmohamed, Jay Lodhia, Patrick Amsi, Jeremia Pyuza, Alex Mremi, Amos Mwasamwaja, Mramba Nyindo, Kondo Chilonga, David Msuya

Published in: World Journal of Surgical Oncology | Issue 1/2017

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Abstract

Background

Colorectal cancer associated with chronic intestinal schistosomiasis has been linked with the chronic inflammation as a result of schistosomal ova deposition in the submucosal layer of the intestine. Among all species Schistosoma japonicum has been more linked to development of colorectal cancer as compared to Schistosoma mansoni due to absence of population-based studies to support the association. Despite the weak evidence, some cases have been reported associating S. mansoni with development of colorectal cancer.

Case Presentation

We report a patient who presented to us as a case of intestinal obstruction and found to have a constrictive lesion at the sigmoid colon at laparotomy, then later found to have colorectal cancer with deposited S. mansoni ova at histology.

Conclusion

Given the known late complications of schistosomiasis, and as S. mansoni is endemic in some parts of Tanzania, epidemiological studies are recommended to shed more light on its association with colorectal cancer.
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Metadata
Title
Colorectal cancer in a patient with intestinal schistosomiasis: a case report from Kilimanjaro Christian Medical Center Northern Zone Tanzania
Authors
Ayesiga M Herman
Alfred Kishe
Heri Babu
Hilary Shilanaiman
Murad Tarmohamed
Jay Lodhia
Patrick Amsi
Jeremia Pyuza
Alex Mremi
Amos Mwasamwaja
Mramba Nyindo
Kondo Chilonga
David Msuya
Publication date
01-12-2017
Publisher
BioMed Central
Published in
World Journal of Surgical Oncology / Issue 1/2017
Electronic ISSN: 1477-7819
DOI
https://doi.org/10.1186/s12957-017-1217-1

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