Skip to main content
Top
Published in: Health and Quality of Life Outcomes 1/2017

Open Access 01-01-2017 | Research

Health related quality of life in Dutch infants, toddlers, and young children

Authors: S. A. Schepers, H. A. van Oers, H. Maurice-Stam, J. Huisman, C. M. Verhaak, M. A. Grootenhuis, L. Haverman

Published in: Health and Quality of Life Outcomes | Issue 1/2017

Login to get access

Abstract

Background

The purpose of this study is to provide Dutch normative data and to assess internal consistency and known-groups validity for the TNO AZL Preschool Children Quality of Life (TAPQOL) and the acute version of the generic Pediatric Quality of Life Inventory (PedsQL 4.0) in Dutch young children aged 0–7 years.

Methods

Participants were selected from a panel of a large Dutch market research agency. A sample of 794 parents (response rate 61%, 39% fathers) of children (53% boys) from the general Dutch population, completed an electronic version of the TAPQOL (N = 227 infants aged 0–1 years) or PedsQL 4.0 (N = 293 toddlers aged 2–4 years and N = 274 young children aged 5–7 years).

Results

Except for the ‘stomach’ scale (α = .39), the TAPQOL showed acceptable to excellent internal consistency (α = .60-.88). The PedsQL 4.0 showed acceptable to excellent reliability in children aged 2–4 years (α = .60–.88) and in children aged 5–7 years (α = .76–.90). Children with a chronic health condition had lower scores than healthy children on 3 out of 12 domains of the TAPQOL (p = .001–.013) and on 2 out of 6 domains of the PedsQL 4.0 for children aged 2–4 years (p = .016–.04). The PedsQL 4.0 differentiated on all domains (p < .05) between children aged 5–7 years with and without a chronic health condition.

Conclusion

In Dutch children aged 0–7 years old, HRQoL can be reliably measured with the TAPQOL and the PedsQL 4.0. However, it remains unclear whether these HRQoL instruments can distinguish between healthy children and children with a chronic health condition under the age of 5.
Literature
1.
go back to reference Varni JW, Seid M, Kurtin PS. PedsQL 4.0: reliability and validity of the Pediatric Quality of Life Inventory version 4.0 generic core scales in healthy and patient populations. Med Care. 2001;39(8):800–12.CrossRefPubMed Varni JW, Seid M, Kurtin PS. PedsQL 4.0: reliability and validity of the Pediatric Quality of Life Inventory version 4.0 generic core scales in healthy and patient populations. Med Care. 2001;39(8):800–12.CrossRefPubMed
2.
go back to reference Connolly MA, Johnson JA. Measuring quality of life in paediatric patients. Pharmacoeconomics. 1999;16(6):605–25.CrossRefPubMed Connolly MA, Johnson JA. Measuring quality of life in paediatric patients. Pharmacoeconomics. 1999;16(6):605–25.CrossRefPubMed
3.
go back to reference Reeve BB, Wyrwich KW, Wu AW, Velikova G, Terwee CB, Snyder CF, Schwartz C, Revicki DA, Moinpour CM, McLeod LD, et al. ISOQOL recommends minimum standards for patient-reported outcome measures used in patient-centered outcomes and comparative effectiveness research. Qual Life Res. 2013;22(8):1889–905.CrossRefPubMed Reeve BB, Wyrwich KW, Wu AW, Velikova G, Terwee CB, Snyder CF, Schwartz C, Revicki DA, Moinpour CM, McLeod LD, et al. ISOQOL recommends minimum standards for patient-reported outcome measures used in patient-centered outcomes and comparative effectiveness research. Qual Life Res. 2013;22(8):1889–905.CrossRefPubMed
4.
go back to reference Varni J, Limbers C, Burwinkle T. How young can children reliably and validly self-report their health-related quality of life?: An analysis of 8,591 children across age subgroups with the PedsQLTM 4.0 Generic Core Scales. Health Qual Life Outcomes. 2007;5(1):1–13.CrossRefPubMedPubMedCentral Varni J, Limbers C, Burwinkle T. How young can children reliably and validly self-report their health-related quality of life?: An analysis of 8,591 children across age subgroups with the PedsQLTM 4.0 Generic Core Scales. Health Qual Life Outcomes. 2007;5(1):1–13.CrossRefPubMedPubMedCentral
5.
go back to reference Bevans KB, Riley AW, Moon J, Forrest CB. Conceptual and methodological advances in child-reported outcomes measurement. Expert Rev Pharmacoecon Outcomes Res. 2010;10(4):385–96.CrossRefPubMedPubMedCentral Bevans KB, Riley AW, Moon J, Forrest CB. Conceptual and methodological advances in child-reported outcomes measurement. Expert Rev Pharmacoecon Outcomes Res. 2010;10(4):385–96.CrossRefPubMedPubMedCentral
6.
go back to reference Klassen AF, Anthony SJ, Khan A, Sung L, Klaassen R. Identifying determinants of quality of life of children with cancer and childhood cancer survivors: a systematic review. Support Care Cancer. 2011;19(9):1275–87.CrossRefPubMed Klassen AF, Anthony SJ, Khan A, Sung L, Klaassen R. Identifying determinants of quality of life of children with cancer and childhood cancer survivors: a systematic review. Support Care Cancer. 2011;19(9):1275–87.CrossRefPubMed
7.
go back to reference Raat H, Landgraf JM, Oostenbrink R, Moll HA, Essink-Bot ML. Reliability and validity of the Infant and Toddler Quality of Life Questionnaire (ITQOL) in a general population and respiratory disease sample. QualLife Res. 2007;16(3):445–60. Raat H, Landgraf JM, Oostenbrink R, Moll HA, Essink-Bot ML. Reliability and validity of the Infant and Toddler Quality of Life Questionnaire (ITQOL) in a general population and respiratory disease sample. QualLife Res. 2007;16(3):445–60.
8.
go back to reference Fekkes M, Theunissen NC, Brugman E, Veen S, Verrips EG, Koopman HM, Vogels T, Wit JM, Verloove-Vanhorick SP. Development and psychometric evaluation of the TAPQOL: a health-related quality of life instrument for 1-5-year-old children. Qual Life Res. 2000;9(8):961–72.CrossRefPubMed Fekkes M, Theunissen NC, Brugman E, Veen S, Verrips EG, Koopman HM, Vogels T, Wit JM, Verloove-Vanhorick SP. Development and psychometric evaluation of the TAPQOL: a health-related quality of life instrument for 1-5-year-old children. Qual Life Res. 2000;9(8):961–72.CrossRefPubMed
9.
go back to reference Landgraf J. Child Health Questionnaires (CHQ). a user’s manual. 1999. Landgraf J. Child Health Questionnaires (CHQ). a user’s manual. 1999.
10.
go back to reference Varni JW, Burwinkle TM, Seid M, Skarr D. The PedsQL 4.0 as a pediatric population health measure: feasibility, reliability, and validity. Ambul Pediatr. 2003;3(6):329–41.CrossRefPubMed Varni JW, Burwinkle TM, Seid M, Skarr D. The PedsQL 4.0 as a pediatric population health measure: feasibility, reliability, and validity. Ambul Pediatr. 2003;3(6):329–41.CrossRefPubMed
11.
go back to reference Campbell N, Ali F, Finlay AY, Salek SS. Equivalence of electronic and paper-based patient-reported outcome measures. Qual Life Res. 2015;24(8):1949–61.CrossRefPubMed Campbell N, Ali F, Finlay AY, Salek SS. Equivalence of electronic and paper-based patient-reported outcome measures. Qual Life Res. 2015;24(8):1949–61.CrossRefPubMed
12.
go back to reference Schepers SA, Haverman L, Zadeh S, Grootenhuis MA, Wiener L. Healthcare Professionals’ preferences and perceived barriers for routine assessment of patient-reported outcomes in pediatric oncology practice: moving toward international processes of change. Pediatr Blood Cancer. 2016;63(12):2181–8.CrossRefPubMed Schepers SA, Haverman L, Zadeh S, Grootenhuis MA, Wiener L. Healthcare Professionals’ preferences and perceived barriers for routine assessment of patient-reported outcomes in pediatric oncology practice: moving toward international processes of change. Pediatr Blood Cancer. 2016;63(12):2181–8.CrossRefPubMed
13.
go back to reference Schepers SA, Sint Nicolaas SM, Haverman L, Wensing M, Schouten van Meeteren AY, Veening MA, Caron HN, Hoogerbrugge PM, Kaspers GJ, Verhaak CM, et al. Real-world implementation of electronic patient-reported outcomes in outpatient pediatric cancer care. Psychooncology. 2016. Schepers SA, Sint Nicolaas SM, Haverman L, Wensing M, Schouten van Meeteren AY, Veening MA, Caron HN, Hoogerbrugge PM, Kaspers GJ, Verhaak CM, et al. Real-world implementation of electronic patient-reported outcomes in outpatient pediatric cancer care. Psychooncology. 2016.
14.
go back to reference Haverman L, van Oers HA, Limperg PF, Hijmans CT, Schepers SA, Sint Nicolaas SM, Verhaak CM, Bouts AHM, Fijnvandraat K, Peters M, et al. Implementation of electronic patient reported outcomes in pediatric daily clinical practice: the KLIK experience. Clin Pract Pediatr Psychol. 2014;2(1):50–67.CrossRef Haverman L, van Oers HA, Limperg PF, Hijmans CT, Schepers SA, Sint Nicolaas SM, Verhaak CM, Bouts AHM, Fijnvandraat K, Peters M, et al. Implementation of electronic patient reported outcomes in pediatric daily clinical practice: the KLIK experience. Clin Pract Pediatr Psychol. 2014;2(1):50–67.CrossRef
15.
go back to reference Engelen V, Haentjens MM, Detmar SB, Koopman HM, Grootenhuis MA. Health related quality of life of Dutch children: psychometric properties of the PedsQL in the Netherlands. BMC Pediatr. 2009;9:68.CrossRefPubMedPubMedCentral Engelen V, Haentjens MM, Detmar SB, Koopman HM, Grootenhuis MA. Health related quality of life of Dutch children: psychometric properties of the PedsQL in the Netherlands. BMC Pediatr. 2009;9:68.CrossRefPubMedPubMedCentral
16.
go back to reference Limperg PF, Haverman L, van Oers HA, Van Rossum MA, Maurice-Stam H, Grootenhuis MA. Health related quality of life in Dutch young adults: psychometric properties of the PedsQL generic core scales young adult version. Health Qual Life Outcomes. 2014;12(1):9.CrossRefPubMedPubMedCentral Limperg PF, Haverman L, van Oers HA, Van Rossum MA, Maurice-Stam H, Grootenhuis MA. Health related quality of life in Dutch young adults: psychometric properties of the PedsQL generic core scales young adult version. Health Qual Life Outcomes. 2014;12(1):9.CrossRefPubMedPubMedCentral
17.
go back to reference van Oers HA, Schepers SA, Grootenhuis MA, Haverman L. Dutch normative data and psychometric properties for the Distress Thermometer for Parents. Qual Life Res. 2017;26:177.CrossRefPubMed van Oers HA, Schepers SA, Grootenhuis MA, Haverman L. Dutch normative data and psychometric properties for the Distress Thermometer for Parents. Qual Life Res. 2017;26:177.CrossRefPubMed
18.
go back to reference Mokkink LB, van der Lee JH, Grootenhuis MA, Offringa M, Heymans HS, Dutch National Consensus Committee Chronic D, Health Conditions in C. Defining chronic diseases and health conditions in childhood (0-18 years of age): national consensus in the Netherlands. Eur J Pediatr. 2008;167(12):1441–7.CrossRefPubMed Mokkink LB, van der Lee JH, Grootenhuis MA, Offringa M, Heymans HS, Dutch National Consensus Committee Chronic D, Health Conditions in C. Defining chronic diseases and health conditions in childhood (0-18 years of age): national consensus in the Netherlands. Eur J Pediatr. 2008;167(12):1441–7.CrossRefPubMed
19.
go back to reference Cronbach LJ. Coefficient alpha and the internal structure of tests. Psychometrika. 1951;16:297–334.CrossRef Cronbach LJ. Coefficient alpha and the internal structure of tests. Psychometrika. 1951;16:297–334.CrossRef
20.
go back to reference Nunnally JC, Bernstein IR. Psychometric theory. 3rd ed. New York: McGraw-Hill; 1994. Nunnally JC, Bernstein IR. Psychometric theory. 3rd ed. New York: McGraw-Hill; 1994.
21.
go back to reference Prior M, Smart D, Sanson A, Oberklaid F. Sex differences in psychological adjustment from infancy to 8 years. J Am Acad Child Adolesc Psychiatry. 1993;32(2):291–304. discussion 305.CrossRefPubMed Prior M, Smart D, Sanson A, Oberklaid F. Sex differences in psychological adjustment from infancy to 8 years. J Am Acad Child Adolesc Psychiatry. 1993;32(2):291–304. discussion 305.CrossRefPubMed
22.
go back to reference Varni JW, Limbers CA, Burwinkle TM. Parent proxy-report of their children’s health-related quality of life: an analysis of 13,878 parents’ reliability and validity across age subgroups using the PedsQL 4.0 Generic Core Scales. Health Qual Life Outcomes. 2007;5:2.CrossRefPubMedPubMedCentral Varni JW, Limbers CA, Burwinkle TM. Parent proxy-report of their children’s health-related quality of life: an analysis of 13,878 parents’ reliability and validity across age subgroups using the PedsQL 4.0 Generic Core Scales. Health Qual Life Outcomes. 2007;5:2.CrossRefPubMedPubMedCentral
23.
go back to reference Field A. Discovering statistics using SPSS. 3rd ed. London: Sage Publications; 2009. Field A. Discovering statistics using SPSS. 3rd ed. London: Sage Publications; 2009.
24.
go back to reference Varni JW, Limbers CA, Neighbors K, Schulz K, Lieu JE, Heffer RW, Tuzinkiewicz K, Mangione-Smith R, Zimmerman JJ, Alonso EM. The PedsQL Infant Scales: feasibility, internal consistency reliability, and validity in healthy and ill infants. Qual Life Res. 2011;20(1):45–55.CrossRefPubMed Varni JW, Limbers CA, Neighbors K, Schulz K, Lieu JE, Heffer RW, Tuzinkiewicz K, Mangione-Smith R, Zimmerman JJ, Alonso EM. The PedsQL Infant Scales: feasibility, internal consistency reliability, and validity in healthy and ill infants. Qual Life Res. 2011;20(1):45–55.CrossRefPubMed
Metadata
Title
Health related quality of life in Dutch infants, toddlers, and young children
Authors
S. A. Schepers
H. A. van Oers
H. Maurice-Stam
J. Huisman
C. M. Verhaak
M. A. Grootenhuis
L. Haverman
Publication date
01-01-2017
Publisher
BioMed Central
Published in
Health and Quality of Life Outcomes / Issue 1/2017
Electronic ISSN: 1477-7525
DOI
https://doi.org/10.1186/s12955-017-0654-4

Other articles of this Issue 1/2017

Health and Quality of Life Outcomes 1/2017 Go to the issue