Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress 2023 EHA Congress 2023 ASCO Annual Meeting
Clinical Collections
Advances in Alzheimer’s

Keynote webinar | Spotlight on sleep in brain health

LIVE: Thursday 2nd May 2024, 18:00-19:30 (CEST)

Quality sleep is essential for health. But what happens to our brains when sleep patterns are disturbed? Join our experts to explore the interplay between sleep disruption and neurological diseases, and the questions that you need to be asking your patients to help you prevent the harmful effects of sleep deprivation.
ADVANCED SEARCH
Log in
Top
Health and Quality of Life Outcomes
Published in: Health and Quality of Life Outcomes 1/2016

Open Access 01-12-2016 | Research

Quality of life in patients with vitiligo: a cross-sectional study based on Vitiligo Quality of Life index (VitiQoL)

Authors: Kosar Hedayat, Mojgan Karbakhsh, Maryam Ghiasi, Azadeh Goodarzi, Yousef Fakour, Zahra Akbari, Afsaneh Ghayoumi, Narges Ghandi

Published in: Health and Quality of Life Outcomes | Issue 1/2016

Login to get access

Abstract

Background

Vitiligo is a multi-factorial pigmentary skin disorder. Recently, the importance of emotional and psychological issues is proposed in incidence, progression, relapse and remission of vitiligo. There are limited studies conducted in developing countries, which assess life quality of patients with vitiligo. The aim of this study was the application and evaluation of a disease-specific quality of life index in Iranian patients, for the first time.

Methods

This cross-sectional biphasic study was conducted on 25 patients as a pilot and another 173 patients as the main study group, in Razi Hospital, Tehran, Iran, 2013–2014. Persian version of Vitiligo Quality of Life index (VitiQoL) was developed with backward-forward method. Based on the pilot study, the validity and reliability were assessed. The Vitiligo Area and Score Index (VASI), VitiQoL, and their relationship, demographic and clinical characteristic of patients were measured.

Results

The Mean and standard deviation of the VitiQoL score was 30.5 ± 14.5 (range 0–60 in Persian version). There was a significant relationship between VASI score and VitiQoL (p = 0.015, r = 0.187). Confirmatory factor analysis revealed three important factors within VitiQoL: participation limitation, stigma, and behavior. In subscale analysis based on behavior factor, female patients had poorer quality of life (p = 0.02). Concomitant psychiatric problems, e.g. anxiety and depression, were not associated with QOL; however, they were near to being meaningful (p = 0.06, r = 0.14).

Conclusion

VitiQoL is a valid index in estimating life quality of vitiligo patients and has proper relation to disease severity. Focusing on patient’s life quality is an important entity in the management of vitiligo patients; relevant supportive group-based consultations and therapies are also important arms when approaching vitiligo.
Appendix
Available only for authorised users
Literature
1.
Bolognia J, Jorizzo J, Schaffer J. Dermatology text book. 3rd ed. 2012. p. 1023–4.
2.
3.
Patel AB, Kubba R, Kubba A. Clinicopathological correlation of acquired hypopigmentary disorders. Indian J Dermatol Venereol Leprol. 2013;79(3):376–82.CrossRefPubMed
4.
Lilly E, Lu PD, Borovicka JH, Victorson D, Kwasny MJ, West DP, et al. Development and validation of a vitiligo-specific quality-of-life instrument (VitiQoL). J Am Acad Dermatol. 2013;69(1):e1–8.CrossRef
5.
Korobko IV. Review of current clinical studies of vitiligo treatments. Dermatol Ther. 2012;25 Suppl 1:S17–27.CrossRefPubMed
6.
Hamzavi I, Jain H, McLean D, Shapiro J, Zeng H, Lui H. Parametric modelling of narrowband UV-B phototherapy for vitiligo, using a novel quantitative tool: the Vitiligo Area Scoring Index. Arch Dermatol. 2004;140(6):677–83.CrossRefPubMed
7.
Taiieb A, Picardo M. The definition and assessment of vitiligo: a consensus report of the Vitiligo European Task Force. Pigment Cell Melanoma Res. 2007;20(1):27–35.CrossRef
8.
Chan MF, Chua TL, Goh BK, Aw CW, Thng TG, Lee SM. Investigating factors associated with depression of vitiligo patients in Singapore. J Clin Nurs. 2012;21(11-12):1614–21.CrossRefPubMed
9.
Mattoo SK, Handa S, Kaur I, Gupta N, Malhotra R. Psychiatric morbidity in vitiligo: prevalence and correlates in India. J Eur Acad Dermatol Venereol. 2002;16:573–8.CrossRefPubMed
10.
Porter JR, Beuf AH, Lerner A, Nordlund J. Psychosocial effect of vitiligo: a comparison of vitiligo patients with ‘‘normal’’ control subjects, with psoriasis patients, and with patients with other pigmentary disorders. Journal of the American Academy of Dermatology. 1986; 15:220-4.
11.
Firooz A, Bouzari N, Fallah N, Ghazisaidi B, Firoozabadi MR, Dowlati Y. What patients with vitiligo believe about their condition? International journal of dermatology. 2004 Nov; 43(11):811-4.
12.
Talsania N, Lamb B, Bewley A. Vitiligo is more than skin deep: a survey of members of the Vitiligo Society. Clinical and Experimental Dermatology. 2010; 35:736-9.
13.
Wang KY, Wang KH, Zhang ZP. Health-related quality of life and marital quality of vitiligo patients in China. Journal of the European Academy of Dermatology and Venereology. 2011; 25:429-35.
14.
Kent G, Al’Abadie M. Psychologic effects of vitiligo: a critical incident analysis. Journal of the American Academy of Dermatology. 1996; 35:895-8.
15.
Linthorst Homan MW, Spuls PI, de Korte J, Bos JD, Sprangers MA, Van der Veen JP. The burden of vitiligo: patient characteristics associated with quality of life. Journal of the American Academy of Dermatology. 2009 Sep; 61(3): 411-20.
16.
Weber MB, Lorenzini D, Reinehr CP, Lovato B. Assessment of the quality of life of pediatric patients at a center of excellence in dermatology in southern Brazil. Anais Brasileiros de Dermatologia. 2012 Sep-Oct; 87(5): 697-702.
17.
Parsad D, Dogra S, Kanwar AJ. Quality of life in patients with vitiligo: Health and Quality of Life Outcomes. 2003; 1:58.
18.
Borimnejad L, Yekta ZP, Nasrabadi AN. Lived Experience of Women Suffering from Vitiligo: A Phenomenological Study. The Qualitative Report. 2006; 11(2), 335-349.
19.
Kent G, al-Abadie M. Factors affecting responses on Dermatology Life Quality Index items among vitiligo sufferers. Clin Exp Dermatol. 1996;21:330–3.
20.
Dolatshahi M, Ghazi P, Feizy V, Hemami M. Life quality assessment among patients with vitiligo: Comparison of married and single patients in Iran. Indian J Dermatol Venereol Leprol. 2008;74(6):700.PubMed
21.
Komen L, da Graça V, Wolkerstorfer A, de Rie MA, Terwee CB, Van der Veen JP. Vitiligo Area Scoring Index and Vitiligo European Task Force assessment: reliable and responsive instruments to measure the degree of depigmentation in vitiligo. British Journal of Dermatology. 2015 Feb; 172(2):437-43.
22.
Mashayekhi V, Javidi Z, Kiafar B, Manteghi AA, Saadatian V, Esmaeili HA, et al. Quality of life in patients with vitiligo: A descriptive study on 83 patients attending a PUVA therapy unit in Imam Reza Hospital, Mashad. Indian Journal of dermatology and venereology and leprology. 2010; 76:592.
23.
Ghajarzadeh M, Ghiasi M, Kheirkhah S. Associations between skin diseases and quality of life: a comparison of psoriasis, vitiligo, and alopecia area. Acta Medica Iranica journal. 2012;50(7):511-5.
24.
Aghaei S, Sodaifi M, Jafari P, Mazharinia N, Andrew Y. DLQI scores in vitiligo: reliability and validity of the Persian version. Biomed central dermatology. 2004; 4:8.
25.
Borimnejad L, Parsa Yekta Z, Nikbakht-Nasrabadi A, Firooz A. Quality of life with vitiligo: comparison of male and female Muslim patients in Iran. Gender Medicine journal. 2006 Jun; 3(2):124-30.
26.
Catucci Boza J, Fabbrin A, Giongo N, Kundu R, Horn R, Ferreira Cestari T. Translation, cross-cultural adaptation and validation of the vitiligo-specific health-related quality of life instrument (VitiQoL) into Brazilian Portuguese. An Bras Dermatol. 2015;90(3):358–62.CrossRef
27.
Ongenae K, Dierckxsens L, Brochez L, van Geel N, Naeyaert JM. Quality of Life and Stigmatization Profile in a Cohort of Vitiligo Patients and Effect of the Use of Camouflage. Clinical and Laboratory Investigations Dermatology. 2005;210:279–85.
28.
Sharifi V, Amin-Esmaeili M, Hajebi A, Motevalian A, Radgoodarzi R, Hefazi M, et al. Twelve-month prevalence and correlates of psychiatric Disorders in Iran: The Iranian Mental Health Survey, 2011. Arch Iran Med. 2015;18(2):76–84.
Metadata
Title
Quality of life in patients with vitiligo: a cross-sectional study based on Vitiligo Quality of Life index (VitiQoL)
Authors
Kosar Hedayat
Mojgan Karbakhsh
Maryam Ghiasi
Azadeh Goodarzi
Yousef Fakour
Zahra Akbari
Afsaneh Ghayoumi
Narges Ghandi
Publication date
01-12-2016
Publisher
BioMed Central
Published in
Health and Quality of Life Outcomes / Issue 1/2016
Electronic ISSN: 1477-7525
DOI
https://doi.org/10.1186/s12955-016-0490-y

Other articles of this Issue 1/2016

Health and Quality of Life Outcomes 1/2016 Go to the issue

Research

From early detection to rehabilitation in the community: reading beyond the blog testimonies of survivors’ quality of life and prostate cancer representation

Research

Long-term follow-up of mental health, health-related quality of life and associations with motor skills in young adults born preterm with very low birth weight

Research

Estimation of utility weights for human papilloma virus-related health states according to disease severity

Research

Association between general self-efficacy, social support, cancer-related stress and physical health-related quality of life: a path model study in patients with neuroendocrine tumors

Research

Victimisation, poly-victimisation and health-related quality of life among high school students in Vietnam: a cross-sectional survey

Research

Quality of life, depression and dietary intake in Obstructive Sleep Apnea patients