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Published in: Malaria Journal 1/2017

Open Access 01-12-2017 | Research

Social and cultural complexities of anti-malarial drug circulation: an ethnographic investigation in three rural remote communes of Cambodia

Author: Phasy Res

Published in: Malaria Journal | Issue 1/2017

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Abstract

Background

Anti-malarial medicine has a central role in malaria case management in Cambodia. It is, therefore, essential to study how anti-malarial drugs are distributed and consumed. This study aims to understand the socio-cultural complexity of anti-malarial drugs provision and usage practices.

Methods

Semi-structured interviews and observation were conducted in Cambodia at the communal, provincial, and national levels from January 2014 to January 2015. Health ministers, non-governmental officers, anti-malarial medicines distributors, village malaria volunteers and malaria patients were interviewed.

Findings

The findings show that artemisinin-based combination therapy (ACT) flows into unregulated outlets, and was sold without any diagnostic tests. Affordable Medicines Facility for malaria scheme (AMFm) cannot drive ineffective anti-malarial medicines out of the market because ACT is still more expensive due to price absortion by private and public providers. Malaria patients might not consume ACT because of patients’ notions of ‘Korp’, and pharmaceutical and parasitic familiarity. The findings reflect that neither public nor private institutions have the capacity and resources to control the flow of ACT from going into the unlicensed sector. They do not have the ability to ensure that ACT is consumed after a positive rapid diagnostic test.

Conclusions

With a weak regulation system and ailing public health infrastructure, pharmaceutical-neoliberal mechanism like AMFm is not an effective means to eradicate any forms of malaria. Therefore, horizontal programmes, such as public health infrastructure improvement, and population participation must be implemented. Ethnical responsibilities of medical practitioners must be enforced and be included into the national curriculum. The awareness of drug resistance must be implemented at all levels.
Literature
3.
go back to reference Talisuna A, Adibaku S, Amojah CN, Amofah GK, Aubyn V, Dodoo A, et al. The affordable medicines facility-malaria—a success in peril. Malar J. 2012;11:370.CrossRefPubMedPubMedCentral Talisuna A, Adibaku S, Amojah CN, Amofah GK, Aubyn V, Dodoo A, et al. The affordable medicines facility-malaria—a success in peril. Malar J. 2012;11:370.CrossRefPubMedPubMedCentral
4.
go back to reference Yamey G, Schäferhoff M, Montagu D. Piloting the affordable medicines facility-malaria: what will success look like? Bull World Health Organ. 2012;90:452–60.PubMedPubMedCentral Yamey G, Schäferhoff M, Montagu D. Piloting the affordable medicines facility-malaria: what will success look like? Bull World Health Organ. 2012;90:452–60.PubMedPubMedCentral
5.
go back to reference Ministry of Health. The National Strategic Plan for Elimination of Malaria in the Kingdom of Cambodia 2011-2025. Policy guidelines. 2011. Ministry of Health. The National Strategic Plan for Elimination of Malaria in the Kingdom of Cambodia 2011-2025. Policy guidelines. 2011.
6.
go back to reference Yeung S, van Damme W, Socheat D, White NJ, Mills A. Access to artemisinin combination therapy for malaria in remote areas of Cambodia. Malar J. 2008;7:96.CrossRefPubMedPubMedCentral Yeung S, van Damme W, Socheat D, White NJ, Mills A. Access to artemisinin combination therapy for malaria in remote areas of Cambodia. Malar J. 2008;7:96.CrossRefPubMedPubMedCentral
7.
go back to reference Mey Bouth D. Malaria in Cambodia. Mekong Malaria Forum. 1999;2:22–4. Mey Bouth D. Malaria in Cambodia. Mekong Malaria Forum. 1999;2:22–4.
8.
go back to reference Noedl H. Evidence of artemisinin-resistant malaria in Western Cambodia. N Engl J Med. 2008;359:2619–20.CrossRefPubMed Noedl H. Evidence of artemisinin-resistant malaria in Western Cambodia. N Engl J Med. 2008;359:2619–20.CrossRefPubMed
9.
go back to reference Rogers W, Sem R, Tero T, Chim P, Lim P, Muth S, et al. Failure of artesunate-mefloquine combination therapy for uncomplicated Plasmodium falciparum in southern Cambodia. Malar J. 2009;8:10.CrossRefPubMedPubMedCentral Rogers W, Sem R, Tero T, Chim P, Lim P, Muth S, et al. Failure of artesunate-mefloquine combination therapy for uncomplicated Plasmodium falciparum in southern Cambodia. Malar J. 2009;8:10.CrossRefPubMedPubMedCentral
10.
go back to reference Plowe CV. The evolution of drug-resistance malaria. Trans R Soc Trop Med Hyg. 2009;103(Suppl 1):S11–4.CrossRefPubMed Plowe CV. The evolution of drug-resistance malaria. Trans R Soc Trop Med Hyg. 2009;103(Suppl 1):S11–4.CrossRefPubMed
13.
go back to reference Biehl J. Pharmaceuticalization: AIDS treatment and global health politics. Anthropol Q. 2007;80:1083–126.CrossRef Biehl J. Pharmaceuticalization: AIDS treatment and global health politics. Anthropol Q. 2007;80:1083–126.CrossRef
14.
go back to reference Amaratunga C, Lim P, Suon S, Sreng S, Mao S, Sopha C, et al. Dihydroartemisinin–piperaquine resistance in Plasmodium falciparum malaria in Cambodia: a multisite prospective cohort study. Lancet Infect Dis. 2016;3:357–65.CrossRef Amaratunga C, Lim P, Suon S, Sreng S, Mao S, Sopha C, et al. Dihydroartemisinin–piperaquine resistance in Plasmodium falciparum malaria in Cambodia: a multisite prospective cohort study. Lancet Infect Dis. 2016;3:357–65.CrossRef
15.
go back to reference Ovesen J, Trankell IB. Cambodians and their doctors: a medical anthropology of colonial and post-colonial Cambodia. NIAS Monographs, No.117; 2010. Ovesen J, Trankell IB. Cambodians and their doctors: a medical anthropology of colonial and post-colonial Cambodia. NIAS Monographs, No.117; 2010.
16.
go back to reference Andreopoulos G, Andreopoulos GC, Panayides A. Understanding the complexities of the supply chain’s linkages: the case of anti-malaria drugs in Africa. J Acad Bus Econ. 2014;14:119–24.CrossRef Andreopoulos G, Andreopoulos GC, Panayides A. Understanding the complexities of the supply chain’s linkages: the case of anti-malaria drugs in Africa. J Acad Bus Econ. 2014;14:119–24.CrossRef
17.
go back to reference Manyando C, Njunju EM, Chileshe J, Siziya S, Shiff C. Rapid diagnostic tests for malaria and health workers’ adherence to test results at health facilities in Zambia. Malar J. 2014;13:166.CrossRefPubMedPubMedCentral Manyando C, Njunju EM, Chileshe J, Siziya S, Shiff C. Rapid diagnostic tests for malaria and health workers’ adherence to test results at health facilities in Zambia. Malar J. 2014;13:166.CrossRefPubMedPubMedCentral
18.
go back to reference Dalrymple DG. Artemisia annua, Artemisinin, ACTs & Malaria Control in Africa. Washington D.C: Connecticut Ave; 2012. Dalrymple DG. Artemisia annua, Artemisinin, ACTs & Malaria Control in Africa. Washington D.C: Connecticut Ave; 2012.
19.
go back to reference Hanson K. Public and private roles in malaria control: the contributions of economic analysis. Am J Trop Med Hyg. 2004;71:168–73.PubMed Hanson K. Public and private roles in malaria control: the contributions of economic analysis. Am J Trop Med Hyg. 2004;71:168–73.PubMed
20.
go back to reference Van der Geest S, Whyte SR, Hardon A. The anthropology of pharmaceuticals: a biographical approach. Ann Rev Anthropol. 1996;25:153–78.CrossRef Van der Geest S, Whyte SR, Hardon A. The anthropology of pharmaceuticals: a biographical approach. Ann Rev Anthropol. 1996;25:153–78.CrossRef
21.
go back to reference Nichter M, Nitchter M. Anthropology and International Health: Asian Case Studies. Hove: Psychology Press; 1996. Nichter M, Nitchter M. Anthropology and International Health: Asian Case Studies. Hove: Psychology Press; 1996.
22.
go back to reference Packard RM. Malaria dreams: postwar visions of health and development in the third world. Med Anthropol. 1997;17:279–96.CrossRefPubMed Packard RM. Malaria dreams: postwar visions of health and development in the third world. Med Anthropol. 1997;17:279–96.CrossRefPubMed
23.
go back to reference Ecks S. Pharmaceutical citizenship: antidepressant marketing and the promise of demarginalization in India. Anthropol Med. 2005;12:239–54.CrossRefPubMed Ecks S. Pharmaceutical citizenship: antidepressant marketing and the promise of demarginalization in India. Anthropol Med. 2005;12:239–54.CrossRefPubMed
24.
go back to reference Taylor M, Harper I. The politics and anti-politics of the global fund experiment: understanding partnership and bureaucratic expansion in Uganda. Med Anthropol. 2014;33:206–22.CrossRefPubMed Taylor M, Harper I. The politics and anti-politics of the global fund experiment: understanding partnership and bureaucratic expansion in Uganda. Med Anthropol. 2014;33:206–22.CrossRefPubMed
25.
go back to reference Cooke B, Kothari U. Participation: the new tyranny?. London: Zen Books; 2001. Cooke B, Kothari U. Participation: the new tyranny?. London: Zen Books; 2001.
27.
go back to reference Lowe RF, Montagu D. Legislation, regulation, and consolidation in the retail pharmacy sector in low-income countries. South Med Rev. 2009;2:35–44. Lowe RF, Montagu D. Legislation, regulation, and consolidation in the retail pharmacy sector in low-income countries. South Med Rev. 2009;2:35–44.
29.
go back to reference Nájera JA, González-Silva M, Alonso PL. Some lessons for the future from the Global malaria Eradication programme (1955–1969). PLoS Med. 2011;8:e1000412.CrossRefPubMedPubMedCentral Nájera JA, González-Silva M, Alonso PL. Some lessons for the future from the Global malaria Eradication programme (1955–1969). PLoS Med. 2011;8:e1000412.CrossRefPubMedPubMedCentral
Metadata
Title
Social and cultural complexities of anti-malarial drug circulation: an ethnographic investigation in three rural remote communes of Cambodia
Author
Phasy Res
Publication date
01-12-2017
Publisher
BioMed Central
Published in
Malaria Journal / Issue 1/2017
Electronic ISSN: 1475-2875
DOI
https://doi.org/10.1186/s12936-017-2082-7

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