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Published in: Malaria Journal 1/2017

Open Access 01-12-2017 | Research

The use of respondent-driven sampling to assess malaria knowledge, treatment-seeking behaviours and preventive practices among mobile and migrant populations in a setting of artemisinin resistance in Western Cambodia

Authors: Po Ly, Julie Thwing, Colleen McGinn, Cesia E. Quintero, Narann Top-Samphor, Najibullah Habib, Jack S. Richards, Sara E. Canavati, Seshu Babu Vinjamuri, Chea Nguon

Published in: Malaria Journal | Issue 1/2017

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Abstract

Background

Multi-drug-resistant Plasmodium falciparum threatens malaria elimination efforts in Cambodia and the Greater Mekong Subregion (GMS). Malaria burden in the GMS is higher among certain high-risk demographic groups in Cambodia, especially among migrant and mobile populations (MMPs). This respondent driven sampling (RDS) study was conducted in order to determine malaria knowledge, treatment-seeking behaviours and preventive practices among two MMP groups in Western Cambodia.

Methods

An RDS survey of MMPs was implemented in four purposively-selected communes along the Thai–Cambodia border; two in Veal Veang District and two in Pailin Province, chosen due to their sizeable MMP groups, their convenience of access, and their proximity to Thailand, which allowed for comparison with RDS studies in Thailand.

Results

There were 764 participants in Pailin Province and 737 in Veal Veang District. Health messages received in Veal Veang were most likely to come from billboards (76.5%) and family and friends (57.7%), while in Pailin they were most likely to come from sources like radio (57.1%) and television (31.3%). Knowledge of malaria transmission by mosquito and prevention by bed net was above 94% in both locations, but some misinformation regarding means of transmission and prevention methods existed, predominantly in Veal Veang. Ownership of treated bed nets was lower in Pailin than in Veal Veang (25.3% vs 53.2%), while reported use the night before the survey was higher in Pailin than in Veal Veang (57.1% vs 31.6%). Use of private sector health and pharmaceutical services was common, but 81.1% of patients treated for malaria in Pailin and 86.6% in Veal Veang had received a diagnostic test. Only 29.6% of patients treated in Pailin and 19.6% of those treated in Veal Veng reported receiving the indicated first-line treatment.

Discussion

Barriers in access to malaria prevention and case management were common among MMPs, with marked variation by site. Resolving both nation-wide and MMP-specific challenges will require targeted interventions that take into account this heterogeneity.
Literature
1.
go back to reference Maude R, Nguon C, Ly P, Bunkea T, Ngor P, Canavati de la Torre S, et al. Spatial and temporal epidemiology of clinical malaria in Cambodia 2004–2013. Malar J. 2014;13:385.CrossRefPubMedPubMedCentral Maude R, Nguon C, Ly P, Bunkea T, Ngor P, Canavati de la Torre S, et al. Spatial and temporal epidemiology of clinical malaria in Cambodia 2004–2013. Malar J. 2014;13:385.CrossRefPubMedPubMedCentral
2.
go back to reference Ashley EA, Dhorda M, Fairhurst RM, Amaratunga C, Lim P, Suon S, et al. Spread of artemisinin resistance in Plasmodium falciparum malaria. N Engl J Med. 2014;371:411–23.CrossRefPubMedPubMedCentral Ashley EA, Dhorda M, Fairhurst RM, Amaratunga C, Lim P, Suon S, et al. Spread of artemisinin resistance in Plasmodium falciparum malaria. N Engl J Med. 2014;371:411–23.CrossRefPubMedPubMedCentral
3.
go back to reference Dondorp AM, Fairhurst RM, Slutsker L, Macarthur JR, Breman JG, Guerin PJ, et al. The threat of artemisinin-resistant malaria. N Engl J Med. 2011;365:1073–5.CrossRefPubMedPubMedCentral Dondorp AM, Fairhurst RM, Slutsker L, Macarthur JR, Breman JG, Guerin PJ, et al. The threat of artemisinin-resistant malaria. N Engl J Med. 2011;365:1073–5.CrossRefPubMedPubMedCentral
4.
go back to reference Phyo A, Nkhoma S, Stepniewska K, Ashley E, Nair S, McGready R, et al. Emergence of artemisinin-resistant malaria on the western border of Thailand: a longitudinal study. Lancet. 2012;379:1960–6.CrossRefPubMedPubMedCentral Phyo A, Nkhoma S, Stepniewska K, Ashley E, Nair S, McGready R, et al. Emergence of artemisinin-resistant malaria on the western border of Thailand: a longitudinal study. Lancet. 2012;379:1960–6.CrossRefPubMedPubMedCentral
5.
go back to reference Denis MB, Tsuyuoka R, Lim P, Lindegardh N, Yi P, Top SN, et al. Efficacy of artemether–lumefantrine for the treatment of uncomplicated falciparum malaria in northwest Cambodia. Trop Med Int Health. 2006;11:1800–7.CrossRefPubMed Denis MB, Tsuyuoka R, Lim P, Lindegardh N, Yi P, Top SN, et al. Efficacy of artemether–lumefantrine for the treatment of uncomplicated falciparum malaria in northwest Cambodia. Trop Med Int Health. 2006;11:1800–7.CrossRefPubMed
6.
7.
go back to reference Canavati SE, Lawford HLS, Fatunmbi BS, Lek D, Top-Samphor N, Leang R, et al. Establishing research priorities for malaria elimination in the context of the emergency response to artemisinin resistance framework-the Cambodian approach. Malar J. 2016;15:120.CrossRefPubMedPubMedCentral Canavati SE, Lawford HLS, Fatunmbi BS, Lek D, Top-Samphor N, Leang R, et al. Establishing research priorities for malaria elimination in the context of the emergency response to artemisinin resistance framework-the Cambodian approach. Malar J. 2016;15:120.CrossRefPubMedPubMedCentral
8.
go back to reference Edwards HM, Canavati SE, Rang C, Ly P, Sovannaroth S, Canier L, et al. Novel cross-border approaches to optimise identification of asymptomatic and artemisinin-resistant Plasmodium infection in mobile populations crossing Cambodian borders. PLoS ONE. 2015;10:e0124300.CrossRefPubMedPubMedCentral Edwards HM, Canavati SE, Rang C, Ly P, Sovannaroth S, Canier L, et al. Novel cross-border approaches to optimise identification of asymptomatic and artemisinin-resistant Plasmodium infection in mobile populations crossing Cambodian borders. PLoS ONE. 2015;10:e0124300.CrossRefPubMedPubMedCentral
9.
go back to reference Guyant P, Canavati SE, Chea N, Ly P, Whittaker M, Roca-Feltrer A, et al. Malaria and the mobile and migrant population in Cambodia: a population movement framework to inform strategies for malaria control and elimination. Malar J. 2015;14:252.CrossRefPubMedPubMedCentral Guyant P, Canavati SE, Chea N, Ly P, Whittaker M, Roca-Feltrer A, et al. Malaria and the mobile and migrant population in Cambodia: a population movement framework to inform strategies for malaria control and elimination. Malar J. 2015;14:252.CrossRefPubMedPubMedCentral
10.
go back to reference Cotter C, Sturrock H, Hsiang M, Liu J, Phillips A, Hwang J, et al. The changing epidemiology of malaria elimination: new strategies for new challenges. Lancet. 2013;382:900–11.CrossRefPubMed Cotter C, Sturrock H, Hsiang M, Liu J, Phillips A, Hwang J, et al. The changing epidemiology of malaria elimination: new strategies for new challenges. Lancet. 2013;382:900–11.CrossRefPubMed
11.
go back to reference Cohen J, Smith D, Cotter C, Ward A, Yamey G, Sabot O, et al. Malaria resurgence: a systematic review and assessment of its causes. Malar J. 2012;11:122.CrossRefPubMedPubMedCentral Cohen J, Smith D, Cotter C, Ward A, Yamey G, Sabot O, et al. Malaria resurgence: a systematic review and assessment of its causes. Malar J. 2012;11:122.CrossRefPubMedPubMedCentral
12.
go back to reference Feachem R, Phillips A, Hwang J, Cotter C, Wielgosz B, Greenwood B, et al. Shrinking the malaria map: progress and prospects. Lancet. 2010;376:1566–78.CrossRefPubMedPubMedCentral Feachem R, Phillips A, Hwang J, Cotter C, Wielgosz B, Greenwood B, et al. Shrinking the malaria map: progress and prospects. Lancet. 2010;376:1566–78.CrossRefPubMedPubMedCentral
13.
go back to reference Sturrock H, Hsiang M, Cohen J, Smith D, Greenhouse B, Bousema T, et al. Targeting asymptomatic malaria infections: active surveillance in control and elimination. PLoS Med. 2013;10:e1001467.CrossRefPubMedPubMedCentral Sturrock H, Hsiang M, Cohen J, Smith D, Greenhouse B, Bousema T, et al. Targeting asymptomatic malaria infections: active surveillance in control and elimination. PLoS Med. 2013;10:e1001467.CrossRefPubMedPubMedCentral
14.
go back to reference Canavati SE, Chea N, Guyant P, Roca-Feltrer A, Yeung S. Strategy to address migrant and mobile populations for malaria elimination in Cambodia, MMP Strategy. Phnom Penh: National Center for Parasitology, Entomology and Malaria Control (CNM); 2013. Canavati SE, Chea N, Guyant P, Roca-Feltrer A, Yeung S. Strategy to address migrant and mobile populations for malaria elimination in Cambodia, MMP Strategy. Phnom Penh: National Center for Parasitology, Entomology and Malaria Control (CNM); 2013.
15.
go back to reference Yeung S, Van Damme W, Socheat D, White N, Mills A. Access to artemisinin combination therapy for malaria in remote areas of Cambodia. Malar J. 2008;7:96.CrossRefPubMedPubMedCentral Yeung S, Van Damme W, Socheat D, White N, Mills A. Access to artemisinin combination therapy for malaria in remote areas of Cambodia. Malar J. 2008;7:96.CrossRefPubMedPubMedCentral
17.
go back to reference Prothero R. Population movements and problems of malaria eradication in Africa. Bull World Health Organ. 1961;24:405–25.PubMedPubMedCentral Prothero R. Population movements and problems of malaria eradication in Africa. Bull World Health Organ. 1961;24:405–25.PubMedPubMedCentral
19.
go back to reference Guyant P, Canavati SE, Chea N, Ly P, Whittaker MA, Roca-Feltrer A, et al. Malaria and the mobile and migrant population in Cambodia: a population movement framework to inform strategies for malaria control and elimination. Malar J. 2015;14:252.CrossRefPubMedPubMedCentral Guyant P, Canavati SE, Chea N, Ly P, Whittaker MA, Roca-Feltrer A, et al. Malaria and the mobile and migrant population in Cambodia: a population movement framework to inform strategies for malaria control and elimination. Malar J. 2015;14:252.CrossRefPubMedPubMedCentral
20.
go back to reference Heckathorn D. Respondent-driven sampling: a new approach to the study of hidden populations. Soc Problem. 1997;44:174–99.CrossRef Heckathorn D. Respondent-driven sampling: a new approach to the study of hidden populations. Soc Problem. 1997;44:174–99.CrossRef
21.
go back to reference Magnani R. Snowball and respondent-driven sampling. In: Behavioral surveillance surveys: guidelines for repeated behavioral surveys in populations at risk of HIV, Chap 4. Chicago: University of Illinois; 2003. Magnani R. Snowball and respondent-driven sampling. In: Behavioral surveillance surveys: guidelines for repeated behavioral surveys in populations at risk of HIV, Chap 4. Chicago: University of Illinois; 2003.
22.
go back to reference Dondorp AM, Nosten F, Yi P, Das D, Phyo AP, Tarning J, et al. Artemisinin resistance in Plasmodium falciparum malaria. N Engl J Med. 2009;361:455–67.CrossRefPubMedPubMedCentral Dondorp AM, Nosten F, Yi P, Das D, Phyo AP, Tarning J, et al. Artemisinin resistance in Plasmodium falciparum malaria. N Engl J Med. 2009;361:455–67.CrossRefPubMedPubMedCentral
23.
go back to reference Wangroongsarb P, Satimai W, Khamsiriwatchara A, Thwing J, Eliades J, Kaewkungwal J, et al. Respondent-driven sampling on the Thailand–Cambodia border. II. Knowledge, perception, practice and treatment-seeking behaviour of migrants in malaria endemic zones. Malar J. 2011;10:117.CrossRefPubMedPubMedCentral Wangroongsarb P, Satimai W, Khamsiriwatchara A, Thwing J, Eliades J, Kaewkungwal J, et al. Respondent-driven sampling on the Thailand–Cambodia border. II. Knowledge, perception, practice and treatment-seeking behaviour of migrants in malaria endemic zones. Malar J. 2011;10:117.CrossRefPubMedPubMedCentral
24.
go back to reference Khamsiriwatchara A, Wangroongsarb P, Thwing J, Eliades J, Satimai W, Delacollette C. Respondent-driven sampling on the Thailand–Cambodia border. II. Knowledge, perception, practice and treatment-seeking behaviour of migrants in malaria endemic zones. Malar J. 2011;10:117.CrossRefPubMedPubMedCentral Khamsiriwatchara A, Wangroongsarb P, Thwing J, Eliades J, Satimai W, Delacollette C. Respondent-driven sampling on the Thailand–Cambodia border. II. Knowledge, perception, practice and treatment-seeking behaviour of migrants in malaria endemic zones. Malar J. 2011;10:117.CrossRefPubMedPubMedCentral
26.
go back to reference Canavati SE, Lawpoolsri S, Quintero CE, Nguon C, Ly P, Pukrittayakamee S, et al. Village malaria worker performance key to the elimination of artemisinin-resistant malaria: a Western Cambodia health system assessment. Malar J. 2016;15:282.CrossRefPubMedPubMedCentral Canavati SE, Lawpoolsri S, Quintero CE, Nguon C, Ly P, Pukrittayakamee S, et al. Village malaria worker performance key to the elimination of artemisinin-resistant malaria: a Western Cambodia health system assessment. Malar J. 2016;15:282.CrossRefPubMedPubMedCentral
28.
go back to reference Yeung S, Van Damme W, Socheat D, White NJ, Mills A. Access to artemisinin combination therapy for malaria in remote areas of Cambodia. Malar J. 2008;7:96.CrossRefPubMedPubMedCentral Yeung S, Van Damme W, Socheat D, White NJ, Mills A. Access to artemisinin combination therapy for malaria in remote areas of Cambodia. Malar J. 2008;7:96.CrossRefPubMedPubMedCentral
29.
go back to reference Yeung S, Damme W, Socheat D, White NJ, Mills A. Cost of increasing access to artemisinin combination therapy: the Cambodian experience. Malar J. 2008;7:84.CrossRefPubMedPubMedCentral Yeung S, Damme W, Socheat D, White NJ, Mills A. Cost of increasing access to artemisinin combination therapy: the Cambodian experience. Malar J. 2008;7:84.CrossRefPubMedPubMedCentral
30.
go back to reference Newton PN, Fernández FM, Plançon A, Mildenhall DC, Green MD, Ziyong L, et al. A collaborative epidemiological investigation into the criminal fake artesunate trade in South East Asia. PLoS Med. 2008;5:e32.CrossRefPubMedPubMedCentral Newton PN, Fernández FM, Plançon A, Mildenhall DC, Green MD, Ziyong L, et al. A collaborative epidemiological investigation into the criminal fake artesunate trade in South East Asia. PLoS Med. 2008;5:e32.CrossRefPubMedPubMedCentral
31.
go back to reference CNM. Report of the Cambodia containment survey 2009 and 2010; 2009–2010. CNM. Report of the Cambodia containment survey 2009 and 2010; 2009–2010.
32.
go back to reference Saunders DL, Vanachayangkul P, Lon C. Dihydroartemisinin–piperaquine failure in Cambodia. N Engl J Med. 2014;371:484–5.CrossRefPubMed Saunders DL, Vanachayangkul P, Lon C. Dihydroartemisinin–piperaquine failure in Cambodia. N Engl J Med. 2014;371:484–5.CrossRefPubMed
33.
go back to reference Leang R, Taylor WR, Bouth DM, Song L, Tarning J, Char MC. Evidence of Plasmodium falciparum malaria multidrug resistance to artemisinin and piperaquine in Western Cambodia: dihydroartemisinin–piperaquine open-label multicenter clinical assessment. Antimicrob Agents Chemother. 2015;59:4719–26.CrossRefPubMedPubMedCentral Leang R, Taylor WR, Bouth DM, Song L, Tarning J, Char MC. Evidence of Plasmodium falciparum malaria multidrug resistance to artemisinin and piperaquine in Western Cambodia: dihydroartemisinin–piperaquine open-label multicenter clinical assessment. Antimicrob Agents Chemother. 2015;59:4719–26.CrossRefPubMedPubMedCentral
34.
go back to reference Malaria Consortium. Workshop to consolidate lessons learned on BCC and mobile/migrant populations in the strategy to contain artemisinin resistant malaria. Meeting Report. Santi Resort & Spa Luang Prabang, Lao PDR5–7 July 2011. Malaria Consortium. Workshop to consolidate lessons learned on BCC and mobile/migrant populations in the strategy to contain artemisinin resistant malaria. Meeting Report. Santi Resort & Spa Luang Prabang, Lao PDR5–7 July 2011.
35.
go back to reference Summary report of the workshop on development of strategy to contain artemisinin resistant malaria among migrants and mobile populations. Malaria Consortium; 2009. Summary report of the workshop on development of strategy to contain artemisinin resistant malaria among migrants and mobile populations. Malaria Consortium; 2009.
Metadata
Title
The use of respondent-driven sampling to assess malaria knowledge, treatment-seeking behaviours and preventive practices among mobile and migrant populations in a setting of artemisinin resistance in Western Cambodia
Authors
Po Ly
Julie Thwing
Colleen McGinn
Cesia E. Quintero
Narann Top-Samphor
Najibullah Habib
Jack S. Richards
Sara E. Canavati
Seshu Babu Vinjamuri
Chea Nguon
Publication date
01-12-2017
Publisher
BioMed Central
Published in
Malaria Journal / Issue 1/2017
Electronic ISSN: 1475-2875
DOI
https://doi.org/10.1186/s12936-017-2003-9

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