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Open Access 01-12-2017 | Commentary

Upon entering an age of global ivermectin-based integrated mass drug administration for neglected tropical diseases and malaria

Author: Frank O. Richards Jr.

Published in: Malaria Journal | Issue 1/2017

Abstract

Ivermectin mass drug administration (MDA) in humans to reduce malaria vectors is yet another use for this remarkable medicine whose discoverers shared the 2015 Nobel Prize in Medicine with the discoverer of artemisinin. The malaria community should join those who have long used ivermectin MDA in an integrated battle to break transmission of three vector-borne parasitic diseases.

The Nobel Assembly at Karolinska Institutet: The 2015 Nobel Prize in Physiology or Medicine (William C. Campbell, Satoshi Ōmura, Youyou Tu)- Press Release. Nobelprize.org. Nobel Media AB 2014. Web. https://www.nobelprize.org/nobel_prizes/medicine/laureates/2015/press.html. Accessed April 2017.

World Health Organization. African Programme for Onchocerciasis Control: progress report, 2014–2015. Wkly Epidemiol Rec. 2015;90:661–74.

World Health Organization. Global programme to eliminate lymphatic filariasis: progress report, 2015. Wkly Epidemiol Rec. 2016;91:441–56.

World Health Organization. Progress towards eliminating onchocerciasis in the WHO Region of the Americas: verification of elimination of transmission in Guatemala. Wkly Epidemiol Rec. 2016;91:501–5.

World Health Organization. Preventive chemotherapy in human helminthiasis. Coordinated use of anthelminthic drugs in control interventions. A manual for health professionals and programme managers. http://apps.who.int/iris/bitstream/10665/43545/1/9241547103_eng.pdf. Accessed Apr 2017.

World Health Organization. Ensuring the timely supply and management of medicines for preventive chemotherapy against neglected tropical diseases. Wkly Epidemiol Rec. 2017;92:155–64.

Richards F, Boatin B, Sauerbrey M, Sékétéli A. Control of onchocerciasis today: status and challenges. Trends Parasitol. 2001;17:558–63.CrossRefPubMed

Richards F, Klein RE, León O, Mendizábal-Cabrera R, Lucía Morales A, Cama V, et al. A knowledge, attitudes and practices survey conducted three years after halting ivermectin mass treatment for onchocerciasis in Guatemala. PLoS Negl Trop Dis. 2016;10:e0004777.CrossRefPubMedPubMedCentral

Hopkins DR, Eigege A, Miri ES, Gontor I, Ogah G, Umaru J, et al. Lymphatic filariasis elimination and schistosomiasis control in combination with onchocerciasis control in Nigeria. Am J Trop Med Hyg. 2002;67:266–72.PubMed

10.

Evans D, Unnasch T, Richards F. Onchocerciasis and lymphatic filariasis elimination in Africa: it’s about time. Lancet. 2015;385:2151–2.CrossRefPubMed

11.

Blackburn B, Eigege A, Miri E, Mathieu E, Richards F. Successful integration of insecticide-treated bednet distribution and mass drug administration in Central Nigeria. Am J Trop Med Hyg. 2006;75:650–5.PubMed

12.

Alout H, Krajacich BJ, Meyers JI, Grubaugh ND, Brackney DE, Kobylinski KC, et al. Evaluation of ivermectin mass drug administration for malaria transmission control across different West African environments. Malar J. 2014;13:417.CrossRefPubMedPubMedCentral

13.

Kobylinski KC, Alout H, Foy BD, Clements A, Adisakwattana P, Swierczewski BE, et al. Rationale for the coadministration of albendazole and ivermectin to humans for malaria parasite transmission control. Am J Trop Med Hyg. 2014;91:655–62.CrossRefPubMedPubMedCentral

14.

Thomsen EK, Sanuku N, Baea M, Satofan S, Maki E, Lombore B, et al. Efficacy, safety, and pharmacokinetics of coadministered diethylcarbamazine, albendazole, and ivermectin for treatment of Bancroftian Filariasis. Clin Infect Dis. 2016;62:334–40.CrossRefPubMed

15.

Chaccour CJ, Rabinovich NR, Slater H, Canavati SE, Bousema T, Lacerda M, et al. Establishment of the ivermectin research for malaria elimination network: updating the research agenda. Malar J. 2015;14:243.CrossRefPubMedPubMedCentral

16.

Gardon J, Gardon-Wendel N, Demanga N, Kamgno J, Chippaux JP, Boussinesq M. Serious reactions after mass treatment of onchocerciasis with ivermectin in an area endemic for Loa loa infection. Lancet. 1997;350:18–22.CrossRefPubMed

17.

Romani L, Whitfeld MJ, Koroivueta J, Kama M, Wand H, Tikoduadua L, et al. Mass drug administration for scabies control in a population with endemic disease. New Eng J Med. 2015;373:2305–13.CrossRefPubMed

18.

Anselmi M, Buonfrate D, Guevara Espinoza A, Prandi R, Marquez M, Gobbo M, et al. Mass administration of ivermectin for the elimination of onchocerciasis significantly reduced and maintained low the prevalence of Strongyloides stercoralis in Esmeraldas, Ecuador. PLoS Negl Trop Dis. 2015;9:e0004150.CrossRefPubMedPubMedCentral

19.

Mectizan Donation Program. http://www.merck.com/about/featured-stories/mectizan.html. Accessed April 2017.

Title: Upon entering an age of global ivermectin-based integrated mass drug administration for neglected tropical diseases and malaria
Author: Frank O. Richards Jr.
Publication date: 01-12-2017
Publisher: BioMed Central
Published in: Malaria Journal / Issue 1/2017
Electronic ISSN: 1475-2875
DOI: https://doi.org/10.1186/s12936-017-1830-z

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