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Malaria Journal
Published in: Malaria Journal 1/2016

Open Access 01-12-2016 | Review

The contribution of agricultural insecticide use to increasing insecticide resistance in African malaria vectors

Authors: Molly C. Reid, F. Ellis McKenzie

Published in: Malaria Journal | Issue 1/2016

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Abstract

The fight against malaria is increasingly threatened by failures in vector control due to growing insecticide resistance. This review examines the recent primary research that addresses the putative relationship between agricultural insecticide use and trends in insecticide resistance. To do so, descriptive evidence offered by the new research was categorized, and additional factors that impact the relationship between agricultural insecticide use and observed insecticide resistance in malaria vectors were identified. In 23 of the 25 relevant recent publications from across Africa, higher resistance in mosquito populations was associated with agricultural insecticide use. This association appears to be affected by crop type, farm pest management strategy and urban development.
Literature
1.
WHO. World malaria report 2014. Geneva: World Health Organization; 2014.
2.
Raghavendra K, Barik TK, Reddy BN, Sharma P, Dash AP. Malaria vector control: from past to future. Parasitol Res. 2011;108:757–79.CrossRefPubMed
3.
WHO. Pesticides and their application: for the control of vectors and pests of public health importance. Geneva: World Health Organization; 2006.
4.
Mouchet J. Mini-review: agriculture and vector resistance. Insect Sci Appl. 1988;9:297–302.
5.
WHO. Global plan for insecticide resistance management in malaria vectors. Geneva: World Health Organization; 2012.
6.
Nkya T, Poupardin R, Laporte F, Akhouayri I, Mosha F, Magesa S, et al. Impact of agriculture on the selection of insecticide resistance in the malaria vector Anopheles gambiae: a multigenerational study in controlled conditions. Parasit Vectors. 2014;7:480.PubMedCentralPubMed
7.
Chouaïbou M, Etang J, Brevault T, Nwane P, Hinzoumbé CK, Mimpfoundi R, et al. Dynamics of insecticide resistance in the malaria vector Anopheles gambiae s.l. from an area of extensive cotton cultivation in Northern Cameroon. Trop Med Int Health. 2008;13:476–86.CrossRefPubMed
8.
Dabiré KR, Diabaté A, Namountougou M, Toe KH, Ouari A, Kengne P, et al. Distribution of pyrethroid and DDT resistance and the L1014F kdr mutation in Anopheles gambiae s.l. from Burkina Faso (West Africa). Trans R Soc Trop Med Hyg. 2009;103:1113–20.CrossRefPubMed
9.
Diabaté A, Baldet T, Chandre F, Akogbéto M, Guiguemde TR, Darriet F, et al. The role of agricultural use of insecticides in resistance to pyrethroids in Anopheles gambiae s.l. in Burkina Faso. Am J Trop Med Hyg. 2002;67:617–22.PubMed
10.
Djogbénou L, Dabiré R, Diabaté A, Kengne P, Akogbéto M, Hougard JM, et al. Identification and geographic distribution of the ACE-1R mutation in the malaria vector Anopheles gambiae in south-western Burkina Faso, West Africa. Am J Trop Med Hyg. 2008;78:298–302.PubMed
11.
Müller P, Chouaïbou M, Pignatelli P, Etang J, Walker ED, Donnelly MJ, et al. Pyrethroid tolerance is associated with elevated expression of antioxidants and agricultural practice in Anopheles arabiensis sampled from an area of cotton fields in Northern Cameroon. Mol Ecol. 2008;17:1145–55.CrossRefPubMed
12.
Mzilahowa T, Ball AJ, Bass C, Morgan JC, Nyoni B, Steen K, et al. Reduced susceptibility to DDT in field populations of Anopheles quadriannulatus and Anopheles arabiensis in Malawi: evidence for larval selection. Med Vet Entomol. 2008;22:258–63.CrossRefPubMed
13.
Nkya TE, Akhouayri I, Poupardin R, Batengana B, Mosha F, Magesa S, et al. Insecticide resistance mechanisms associated with different environments in the malaria vector Anopheles gambiae: a case study in Tanzania. Malar J. 2014;13:28.PubMedCentralCrossRefPubMed
14.
Nwane P, Etang J, Chouaïbou M, Toto JC, Koffi A, Mimpfoundi R, et al. Multiple insecticide resistance mechanisms in Anopheles gambiae s.l. populations from Cameroon, Central Africa. Parasit Vectors. 2013;6:41.PubMedCentralCrossRefPubMed
15.
Tia E, Akogbeto M, Koffi A, Toure M, Adja AM, Moussa K, et al. Situation de la résistance d’Anopheles gambiae s.s. (Diptera: Culicidae) aux pyréthrinoïdes et au DDT dans cinq écosystèmes agricoles de Côte-d’Ivoire. Bull Soc Pathol Exot. 2006;99:278–82.PubMed
16.
Tripet F, Wright J, Cornel A, Fofana A, McAbee R, Meneses C, et al. Longitudinal survey of knockdown resistance to pyrethroid (kdr) in Mali, West Africa, and evidence of its emergence in the Bamako form of Anopheles gambiae s.s. Am J Trop Med Hyg. 2007;76:81–7.PubMed
17.
Yadouléton A, Martin T, Padonou G, Chandre F, Asidi A, Djogbénou L, et al. Cotton pest management practices and the selection of pyrethroid resistance in Anopheles gambiae population in Northern Benin. Parasit Vectors. 2011;4:60.PubMedCentralCrossRefPubMed
18.
Nkya TE, Akhouayri I, Kisinza W, David J-P. Impact of environment on mosquito response to pyrethroid insecticides: facts, evidences and prospects. Insect Biochem Mol Biol. 2013;43:407–16.CrossRefPubMed
19.
Perera MDB, Hemingway J, Karunaratne SP. Multiple insecticide resistance mechanisms involving metabolic changes and insensitive target sites selected in anopheline vectors of malaria in Sri Lanka. Malar J. 2008;7:168.PubMedCentralCrossRefPubMed
20.
Hamon J, Ouedraogo CS. La résistance aux insecticides des vecteurs des paludismes humains dans la zone de l’Office du Niger, au Mali, et dans la région de Soumousso, en Haute-Volta. Bobo-Dioulasso, Burkina Faso: Institut de Recherche pour le Développement; 1969.
21.
Hamon J. L’importance des changements de comportement chez les insectes. Bull World Health Organ. 1963;29(Suppl):115.PubMedCentralPubMed
22.
Hamon J, Garrett-Jones C. Insecticide-resistance in major vectors of malaria, and its operational importance. Geneva: World Health Organization; 1962.
23.
Brun L-O, Sales S. Evolution de la résistance à la dieldrine d’une population sauvage d’Anopheles funestus Giles en l’absence de traitements sélectifs délibérés. Bobo-Dioulasso, Burkina Faso: Institut de Recherche pour le Développement; 1975.
24.
Chapin G, Wasserstrom R. Agricultural production and malaria resurgence in Central America and India. Nature. 1981;293:181–5.CrossRefPubMed
25.
Lines JD. Do agricultural insecticides select for insecticide resistance in mosquitoes? A look at the evidence. Parasitol Today. 1988;4:S17–20.CrossRefPubMed
26.
27.
Koffi AA, Alou LPA, Kabran J-PK, N’Guessan R, Pennetier C. Re-visiting insecticide resistance status in Anopheles gambiae from Côte d’Ivoire: a nation-wide informative survey. PLoS ONE. 2013;8:e82387.PubMedCentralCrossRefPubMed
28.
Kerah-Hinzoumbé C, Péka M, Nwane P, Donan-Gouni I, Etang J, Samè-Ekobo A, et al. Insecticide resistance in Anopheles gambiae from south-western Chad, Central Africa. Malar J. 2008;7:192.PubMedCentralCrossRefPubMed
29.
Dabiré KR, Diabaté A, Namontougou M, Djogbénou L, Kengne P, Simard F, et al. Distribution of insensitive acetylcholinesterase (ace-1R) in Anopheles gambiae s.l. populations from Burkina Faso (West Africa). Trop Med Int Health. 2009;14:396–403.CrossRefPubMed
30.
Dabiré KR, Diabaté A, Wondji C, Chandre F, Simard F, Ouédraogo JB, et al. Trends in insecticide resistance in natural populations of malaria vectors in Burkina Faso, West Africa: 10 years’ surveys. In: Perveen F, editors. Insecticides—pest engineering. INTECH Open Access Publisher; 2012. ISBN 978-953-307-895-3.
31.
Djègbè I, Boussari O, Sidick A, Martin T, Ranson H, Chandre F, et al. Dynamics of insecticide resistance in malaria vectors in Benin: first evidence of the presence of L1014S kdr mutation in Anopheles gambiae from West Africa. Malar J. 2011;10:261.PubMedCentralCrossRefPubMed
32.
Williamson S, Ball A, Pretty J. Trends in pesticide use and drivers for safer pest management in four African countries. Crop Prot. 2008;27:1327–34.CrossRef
33.
34.
Nwane P, Etang J, Chouaïbou M, Toto JC, Kerah-Hinzoumbé C, Mimpfoundi R, et al. Trends in DDT and pyrethroid resistance in Anopheles gambiae s.s. populations from urban and agro-industrial settings in southern Cameroon. BMC Infect Dis. 2009;9:163.PubMedCentralCrossRefPubMed
35.
Abuelmaali SA, Elaagip AH, Basheer MA, Frah EA, Ahmed FT, Elhaj HF, et al. Impacts of agricultural practices on insecticide resistance in the malaria vector Anopheles arabiensis in Khartoum State, Sudan. PLoS One. 2013;8:e80549.PubMedCentralCrossRefPubMed
36.
Corbel V, N’Guessan R, Brengues C, Chandre F, Djogbénou L, Martin T, et al. Multiple insecticide resistance mechanisms in Anopheles gambiae and Culex quinquefasciatus from Benin, West Africa. Acta Trop. 2007;101:207–16.CrossRefPubMed
37.
Dinham B. Growing vegetables in developing countries for local urban populations and export markets: problems confronting small-scale producers. Pest Manag Sci. 2003;59:575–82.CrossRefPubMed
38.
Ijumba JN, Lindsay SW. Impact of irrigation on malaria in Africa: paddies paradox. Med Vet Entomol. 2001;15:1–11.CrossRefPubMed
39.
Muturi EJ, Mwangangi JM, Beier JC, Blackshear M, Wauna J, Sang R, et al. Ecology and behavior of Anopheles arabiensis in relation to agricultural practices in Central Kenya. J Am Mosq Control Assoc. 2013;29:222–30.CrossRefPubMed
40.
Tanaka A, Saito K, Azoma K, Kobayashi K. Factors affecting variation in farm yields of irrigated lowland rice in southern-central Benin. Eur J Agron. 2013;44:46–53.CrossRef
41.
Edi CV, Koudou BG, Jones CM, Weetman D, Ranson H. Multiple-insecticide resistance in Anopheles gambiae mosquitoes, Southern Cote d’Ivoire. Emerg Infect Dis. 2012;18:1508–11.PubMedCentralCrossRefPubMed
42.
Ngowi AVF, Mbise TJ, Ijani ASM, London L, Ajayi OC. Smallholder vegetable farmers in Northern Tanzania: pesticides use practices, perceptions, cost and health effects. Crop Prot. 2007;26:1617–24.PubMedCentralCrossRefPubMed
43.
Djouaka RF, Bakare AA, Coulibaly ON, Akogbéto MC, Ranson H, Hemingway J, et al. Expression of the cytochrome P450s, CYP6P3 and CYP6M2 are significantly elevated in multiple pyrethroid resistant populations of Anopheles gambiae s.s. from Southern Benin and Nigeria. BMC Genom. 2008;9:538.CrossRef
44.
Antonio-Nkondjio C, Fossog BT, Ndo C, Djantio BM, Togouet SZ, Awono-Ambene P, et al. Anopheles gambiae distribution and insecticide resistance in the cities of Douala and Yaounde (Cameroon): influence of urban agriculture and pollution. Malar J. 2011;10:154.PubMedCentralCrossRefPubMed
45.
Badolo A, Traore A, Jones CM, Sanou A, Flood L, Guelbeogo WM, et al. Three years of insecticide resistance monitoring in Anopheles gambiae in Burkina Faso: resistance on the rise. Malar J. 2012;11:232.PubMedCentralCrossRefPubMed
46.
Keiser J, Utzinger J, De Castro MC, Smith TA, Tanner M, Singer BH. Urbanization in sub-saharan Africa and implication for malaria control. Am J Trop Med Hyg. 2004;71(2 suppl):118–27.PubMed
47.
Philbert A, Lyantagaye SL, Nkwengulila G. A review of agricultural pesticides use and the selection for resistance to insecticides in malaria vectors. Adv Entomol. 2014;2:120–8.CrossRef
48.
Fane M, Cissé O, Traore CSF, Sabatier P. Anopheles gambiae resistance to pyrethroid-treated nets in cotton versus rice areas in Mali. Acta Trop. 2012;122:1–6.CrossRefPubMed
49.
Ranson H, N’Guessan R, Lines J, Moiroux N, Nkuni Z, Corbel V. Pyrethroid resistance in African anopheline mosquitoes: What are the implications for malaria control? Trends Parasitol. 2011;27:91–8.CrossRefPubMed
Metadata
Title
The contribution of agricultural insecticide use to increasing insecticide resistance in African malaria vectors
Authors
Molly C. Reid
F. Ellis McKenzie
Publication date
01-12-2016
Publisher
BioMed Central
Published in
Malaria Journal / Issue 1/2016
Electronic ISSN: 1475-2875
DOI
https://doi.org/10.1186/s12936-016-1162-4

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