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Published in: BMC Health Services Research 1/2017

Open Access 01-12-2017 | Research article

Cancer related fatigue: implementing guidelines for optimal management

Authors: Elizabeth J. M. Pearson, Meg E. Morris, Carol E. McKinstry

Published in: BMC Health Services Research | Issue 1/2017

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Abstract

Background

Cancer-related fatigue (CRF) is a key concern for people living with cancer and can impair physical functioning and activities of daily living. Evidence-based guidelines for CRF are available, yet inconsistently implemented globally. This study aimed to identify barriers and enablers to applying a cancer fatigue guideline and to derive implementation strategies.

Methods

A mixed-method study explored the feasibility of implementing the CRF guideline developed by the Canadian Association for Psychosocial Oncology (CAPO). Health professionals, managers and consumers from different practice settings participated in a modified Delphi study with two survey rounds. A reference group informed the design of the study including the surveys. The first round focused on guideline characteristics, compatibility with current practice and experience, and behaviour change. The second survey built upon and triangulated the first round.

Results

Forty-five health practitioners and managers, and 68 cancer survivors completed the surveys. More than 75% of participants endorsed the CAPO cancer related fatigue guidelines. Some respondents perceived a lack of resources for accessible and expert fatigue management services. Further barriers to guideline implementation included complexity, limited practical details for some elements, and lack of clinical tools such as assessment tools or patient education materials. Recommendations to enhance guideline applicability centred around four main themes: (1) balancing the level of detail in the CAPO guideline with ease of use, (2) defining roles of different professional disciplines in CRF management, (3) how best to integrate CRF management into policy and practice, (4) how best to ensure a consumer-focused approach to CRF management.

Conclusions

Translating current knowledge on optimal management of CRF into clinical practice can be enhanced by the adoption of valid guidelines. This study indicates that it is feasible to adopt the CAPO guidelines. Clinical application may be further enhanced with guideline adaptation, professional education and integration with existing practices.
Appendix
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Literature
1.
go back to reference Berger AM, Mitchell SA, Jacobsen PB, Pirl WF. Screening, evaluation, and management of cancer-related fatigue: ready for implementation to practice? CA Cancer J Clin. 2015; doi:10.3322/caac.21268. Berger AM, Mitchell SA, Jacobsen PB, Pirl WF. Screening, evaluation, and management of cancer-related fatigue: ready for implementation to practice? CA Cancer J Clin. 2015; doi:10.​3322/​caac.​21268.
2.
go back to reference Wu H-S, Harden JK. Symptom burden and quality of life in survivorship: a review of the literature. Cancer Nurs. 2015;38:E29–54.CrossRefPubMed Wu H-S, Harden JK. Symptom burden and quality of life in survivorship: a review of the literature. Cancer Nurs. 2015;38:E29–54.CrossRefPubMed
3.
go back to reference Goedendorp MM, Gielissen MFM, Verhagen CA, Bleijenberg G. Psychosocial interventions for reducing fatigue during cancer treatment in adults. Cochrane Database Sys Rev. 2009;2009:Art. No. CD006953. Goedendorp MM, Gielissen MFM, Verhagen CA, Bleijenberg G. Psychosocial interventions for reducing fatigue during cancer treatment in adults. Cochrane Database Sys Rev. 2009;2009:Art. No. CD006953.
4.
go back to reference Spichiger E, Müller-Fröhlich C, Denhaerynck K, Stoll H, Hantikainen V, Dodd M. Prevalence and contributors to fatigue in individuals hospitalized with advanced cancer: a prospective, observational study. Int J Nurs Studies. 2012;49:1146–54.CrossRef Spichiger E, Müller-Fröhlich C, Denhaerynck K, Stoll H, Hantikainen V, Dodd M. Prevalence and contributors to fatigue in individuals hospitalized with advanced cancer: a prospective, observational study. Int J Nurs Studies. 2012;49:1146–54.CrossRef
5.
go back to reference van den Beuken-Everdingen MH, de Rijke JM, Kessels AG, Schouten HC, van Kleef M, Patijn J. Quality of life and non-pain symptoms in patients with cancer. J Pain Symptom Manag. 2009;38:216–33.CrossRef van den Beuken-Everdingen MH, de Rijke JM, Kessels AG, Schouten HC, van Kleef M, Patijn J. Quality of life and non-pain symptoms in patients with cancer. J Pain Symptom Manag. 2009;38:216–33.CrossRef
6.
go back to reference Minton O, Stone PC. How common is fatigue in disease-free breast cancer survivors? A systematic review of the literature. Breast Cancer Res Treat. 2008;112:5–13.CrossRefPubMed Minton O, Stone PC. How common is fatigue in disease-free breast cancer survivors? A systematic review of the literature. Breast Cancer Res Treat. 2008;112:5–13.CrossRefPubMed
7.
go back to reference Carlson LE, Waller A, Groff SL, Giese-Davis J, Bultz BD. What goes up does not always come down: patterns of distress, physical and psychosocial morbidity in people with cancer over a one year period. Psycho-Oncol. 2013;22:168–76.CrossRef Carlson LE, Waller A, Groff SL, Giese-Davis J, Bultz BD. What goes up does not always come down: patterns of distress, physical and psychosocial morbidity in people with cancer over a one year period. Psycho-Oncol. 2013;22:168–76.CrossRef
8.
9.
go back to reference Luciani A, Jacobsen PB, Extermann M, Foa P, Marussi D, Ferrari D, et al. The impact of fatigue and anemia on functional status in older cancer patients treated with chemotherapy. J Geriatr Oncol. 2012;3:182–8.CrossRef Luciani A, Jacobsen PB, Extermann M, Foa P, Marussi D, Ferrari D, et al. The impact of fatigue and anemia on functional status in older cancer patients treated with chemotherapy. J Geriatr Oncol. 2012;3:182–8.CrossRef
10.
go back to reference Boyes AW, Clinton-McHarg T, Waller AE, Steele A, D'Este CA, Sanson-Fisher RW. Prevalence and correlates of the unmet supportive care needs of individuals diagnosed with a haematological malignancy. Acta Oncol. 2014;54:507–14.CrossRefPubMed Boyes AW, Clinton-McHarg T, Waller AE, Steele A, D'Este CA, Sanson-Fisher RW. Prevalence and correlates of the unmet supportive care needs of individuals diagnosed with a haematological malignancy. Acta Oncol. 2014;54:507–14.CrossRefPubMed
11.
go back to reference Hall A, Campbell HS, Sanson-Fisher R, Lynagh M, D'Este C, Burkhalter R, et al. Unmet needs of Australian and Canadian haematological cancer survivors: a cross-sectional international comparative study. Psycho-Oncol. 2013;22:2032–8.CrossRef Hall A, Campbell HS, Sanson-Fisher R, Lynagh M, D'Este C, Burkhalter R, et al. Unmet needs of Australian and Canadian haematological cancer survivors: a cross-sectional international comparative study. Psycho-Oncol. 2013;22:2032–8.CrossRef
12.
go back to reference Harrison MB, Légaré F, Graham ID, Fervers B. Adapting clinical practice guidelines to local context and assessing barriers to their use. Can Med Assoc J. 2010;182:E78–84.CrossRef Harrison MB, Légaré F, Graham ID, Fervers B. Adapting clinical practice guidelines to local context and assessing barriers to their use. Can Med Assoc J. 2010;182:E78–84.CrossRef
13.
go back to reference Hilarius DL, Kloeg PH, van der Wall E, Komen M, Gundy CM, Aaronson NK. Cancer-related fatigue: clinical practice versus practice guidelines. Support Care Cancer. 2011;19:531–8.CrossRefPubMed Hilarius DL, Kloeg PH, van der Wall E, Komen M, Gundy CM, Aaronson NK. Cancer-related fatigue: clinical practice versus practice guidelines. Support Care Cancer. 2011;19:531–8.CrossRefPubMed
14.
go back to reference Borneman T, Koczywas M, Sun VC, Piper BF, Uman G, Ferrell B. Reducing patient barriers to pain and fatigue management. J Pain Symptom Manag. 2010;39:486–501.CrossRef Borneman T, Koczywas M, Sun VC, Piper BF, Uman G, Ferrell B. Reducing patient barriers to pain and fatigue management. J Pain Symptom Manag. 2010;39:486–501.CrossRef
15.
go back to reference Howell D, Keller-Olaman S, Oliver TK, Hack TF, Broadfield L, Biggs K, et al. A pan-Canadian practice guideline and algorithm: screening, assessment, and supportive care of adults with cancer-related fatigue. Curr Oncol. 2013;20:e233–46.CrossRefPubMedPubMedCentral Howell D, Keller-Olaman S, Oliver TK, Hack TF, Broadfield L, Biggs K, et al. A pan-Canadian practice guideline and algorithm: screening, assessment, and supportive care of adults with cancer-related fatigue. Curr Oncol. 2013;20:e233–46.CrossRefPubMedPubMedCentral
16.
go back to reference Pearson EJM, Morris ME, McKinstry CE. Cancer related fatigue: a survey of health practitioner knowledge and practice. Support Care Cancer. 2015;23:3521–9.CrossRefPubMed Pearson EJM, Morris ME, McKinstry CE. Cancer related fatigue: a survey of health practitioner knowledge and practice. Support Care Cancer. 2015;23:3521–9.CrossRefPubMed
17.
go back to reference Abdalrahim MS, Herzallah MS, Zeilani RS, Alhalaiqa F. Jordanian nurses' knowledge and attitudes toward cancer-related fatigue as a barrier of fatigue management. J Am Sci. 2014;10:191–7. Abdalrahim MS, Herzallah MS, Zeilani RS, Alhalaiqa F. Jordanian nurses' knowledge and attitudes toward cancer-related fatigue as a barrier of fatigue management. J Am Sci. 2014;10:191–7.
18.
go back to reference Cheville AL, Shen T, Chang M, Basford JR. Appropriateness of the treatment of fatigued patients with stage IV cancer. Support Care Cancer. 2013;21:229–33.CrossRefPubMed Cheville AL, Shen T, Chang M, Basford JR. Appropriateness of the treatment of fatigued patients with stage IV cancer. Support Care Cancer. 2013;21:229–33.CrossRefPubMed
19.
go back to reference Pearson EJM, Morris ME, McKinstry CE. Cancer-related fatigue: appraising evidence based guidelines for screening, assessment and management. Support Care Cancer. 2016;24:3935–42.CrossRefPubMed Pearson EJM, Morris ME, McKinstry CE. Cancer-related fatigue: appraising evidence based guidelines for screening, assessment and management. Support Care Cancer. 2016;24:3935–42.CrossRefPubMed
20.
go back to reference Prior M, Guerin M, Grimmer-Somers K. The effectiveness of clinical guideline implementation strategies – a synthesis of systematic review findings. J Eval Clin Pract. 2008;14:888–97.CrossRefPubMed Prior M, Guerin M, Grimmer-Somers K. The effectiveness of clinical guideline implementation strategies – a synthesis of systematic review findings. J Eval Clin Pract. 2008;14:888–97.CrossRefPubMed
21.
go back to reference Glasziou P, Haynes B. The paths from research to improved health outcomes. Ev Based Nurs. 2005;8:36–8.CrossRef Glasziou P, Haynes B. The paths from research to improved health outcomes. Ev Based Nurs. 2005;8:36–8.CrossRef
22.
go back to reference Michie S, Johnston M, Abraham C, Lawton R, Parker D, Walker A. Making psychological theory useful for implementing evidence based practice: a consensus approach. Qual Safety Health. 2005;14:26–33.CrossRef Michie S, Johnston M, Abraham C, Lawton R, Parker D, Walker A. Making psychological theory useful for implementing evidence based practice: a consensus approach. Qual Safety Health. 2005;14:26–33.CrossRef
23.
go back to reference Gagliardi AR. Translating knowledge to practice: optimizing the use of guidelines. Epidemiol Psych Sci. 2012;21:231–6.CrossRef Gagliardi AR. Translating knowledge to practice: optimizing the use of guidelines. Epidemiol Psych Sci. 2012;21:231–6.CrossRef
24.
go back to reference Gaddis GM, Greenwald P, Huckson S. Toward improved implementation of evidence-based clinical algorithms: clinical practice guidelines, clinical decision rules, and clinical pathways. Acad Emerg Med. 2007;14:1015–22.CrossRefPubMed Gaddis GM, Greenwald P, Huckson S. Toward improved implementation of evidence-based clinical algorithms: clinical practice guidelines, clinical decision rules, and clinical pathways. Acad Emerg Med. 2007;14:1015–22.CrossRefPubMed
25.
go back to reference Borneman T, Piper BF, Sun VC, Koczywas M, Uman G, Ferrell B. Implementing the fatigue guidelines at one NCCN member institution: process and outcomes. J Natl Compr Cancer Netw. 2007;5:1092–101.CrossRef Borneman T, Piper BF, Sun VC, Koczywas M, Uman G, Ferrell B. Implementing the fatigue guidelines at one NCCN member institution: process and outcomes. J Natl Compr Cancer Netw. 2007;5:1092–101.CrossRef
26.
go back to reference Doyle L, Brady A-M, Byrne G. An overview of mixed methods research. J Res Nurs. 2009;14:175–85.CrossRef Doyle L, Brady A-M, Byrne G. An overview of mixed methods research. J Res Nurs. 2009;14:175–85.CrossRef
27.
go back to reference O’Cathain A, Hoddinott P, Lewin S, Thomas KJ, Young B, Adamson J, et al. Maximising the impact of qualitative research in feasibility studies for randomised controlled trials: guidance for researchers. Pilot Feasibility Stud. 2015;1:32.CrossRefPubMedPubMedCentral O’Cathain A, Hoddinott P, Lewin S, Thomas KJ, Young B, Adamson J, et al. Maximising the impact of qualitative research in feasibility studies for randomised controlled trials: guidance for researchers. Pilot Feasibility Stud. 2015;1:32.CrossRefPubMedPubMedCentral
28.
go back to reference Greene JC, Caracelli VJ, Graham WF. Toward a conceptual framework for mixed-method evaluation designs. Educ Eval Policy Analys. 1989;11:255–74.CrossRef Greene JC, Caracelli VJ, Graham WF. Toward a conceptual framework for mixed-method evaluation designs. Educ Eval Policy Analys. 1989;11:255–74.CrossRef
29.
30.
go back to reference Curry L, Nunez-Smith M. Mixed methods in health sciences research. A practical primer. Thousand Oaks, California, USA: Sage Publications Inc; 2015. Curry L, Nunez-Smith M. Mixed methods in health sciences research. A practical primer. Thousand Oaks, California, USA: Sage Publications Inc; 2015.
31.
go back to reference Tabak RG, Khoong EC, Chambers DA, Brownson RC. Bridging research and practice: models for dissemination and implementation research. Am J Prev Med. 2012;43:337–50.CrossRefPubMedPubMedCentral Tabak RG, Khoong EC, Chambers DA, Brownson RC. Bridging research and practice: models for dissemination and implementation research. Am J Prev Med. 2012;43:337–50.CrossRefPubMedPubMedCentral
32.
go back to reference Brouwers MC, Makarski J, Kastner M, Hayden L, Bhattacharyya O, the GUIDE-M Research Team. The guideline Implementability decision excellence model (GUIDE-M): a mixed methods approach to create an international resource to advance the practice guideline field. Implement Sci. 2015;10:1–11.CrossRef Brouwers MC, Makarski J, Kastner M, Hayden L, Bhattacharyya O, the GUIDE-M Research Team. The guideline Implementability decision excellence model (GUIDE-M): a mixed methods approach to create an international resource to advance the practice guideline field. Implement Sci. 2015;10:1–11.CrossRef
34.
go back to reference Rogers EM. Diffusion of innovations. 5th ed. New York, NY: Free Press; 2003. Rogers EM. Diffusion of innovations. 5th ed. New York, NY: Free Press; 2003.
35.
go back to reference Luxford K, Hill D, Bell R. Promoting the implementation of best-practice guidelines using a matrix tool. Dis Manage Health Outcomes. 2006;14:85–90.CrossRef Luxford K, Hill D, Bell R. Promoting the implementation of best-practice guidelines using a matrix tool. Dis Manage Health Outcomes. 2006;14:85–90.CrossRef
36.
go back to reference Damschroder LJ, Aron DC, Keith RE, Kirsh SR, Alexander JA, Lowery JC. Fostering implementation of health services research findings into practice: a consolidated framework for advancing implementation science. Implement Sci. 2009;4:1–15.CrossRef Damschroder LJ, Aron DC, Keith RE, Kirsh SR, Alexander JA, Lowery JC. Fostering implementation of health services research findings into practice: a consolidated framework for advancing implementation science. Implement Sci. 2009;4:1–15.CrossRef
37.
go back to reference Kirk MA, Kelley C, Yankey N, Birken SA, Abadie B, Damschroder L. A systematic review of the use of the consolidated framework for implementation research. Implement Sci. 2016;11:1–13. Kirk MA, Kelley C, Yankey N, Birken SA, Abadie B, Damschroder L. A systematic review of the use of the consolidated framework for implementation research. Implement Sci. 2016;11:1–13.
39.
go back to reference Kastner M, Bhattacharyya O, Hayden L, Makarski J, Estey E, Durocher L, et al. Guideline uptake is influenced by six implementability domains for creating and communicating guidelines: a realist review. J Clin Epidemiol. 2015;68:498–509.CrossRefPubMed Kastner M, Bhattacharyya O, Hayden L, Makarski J, Estey E, Durocher L, et al. Guideline uptake is influenced by six implementability domains for creating and communicating guidelines: a realist review. J Clin Epidemiol. 2015;68:498–509.CrossRefPubMed
40.
go back to reference Creswell JW, Klassen AC, Plano Clark VL, Smith KC. Best practices for mixed methods research in the health sciences. Office of Behavioral and Social Sciences Research. USA. 2012). Accessed Access 2012. Creswell JW, Klassen AC, Plano Clark VL, Smith KC. Best practices for mixed methods research in the health sciences. Office of Behavioral and Social Sciences Research. USA. 2012). Accessed Access 2012.
41.
go back to reference Sackman H. Delphi critique - expert opinion, forecasting and group process. USA, Canada, England: Lexington Books; 1975. Sackman H. Delphi critique - expert opinion, forecasting and group process. USA, Canada, England: Lexington Books; 1975.
42.
go back to reference Keeney S, McKenna H, Hasson F. The Delphi technique in nursing and health research. Hoboken: Wiley; 2010. Keeney S, McKenna H, Hasson F. The Delphi technique in nursing and health research. Hoboken: Wiley; 2010.
43.
go back to reference Keeney S, Hasson F, McKenna H. Consulting the oracle: ten lessons from using the Delphi technique in nursing research. J Adv Nurs. 2006;53:205–12.CrossRefPubMed Keeney S, Hasson F, McKenna H. Consulting the oracle: ten lessons from using the Delphi technique in nursing research. J Adv Nurs. 2006;53:205–12.CrossRefPubMed
45.
go back to reference Habibi A, Sarafrazi A, Izadyar S. Delphi technique theorietical framework in qualitative research. Int J Eng Sci. 2014;3:8–13. Habibi A, Sarafrazi A, Izadyar S. Delphi technique theorietical framework in qualitative research. Int J Eng Sci. 2014;3:8–13.
46.
go back to reference Shiffman RN, Dixon J, Brandt C, Essaihi A, Hsiao A, Michel G, et al. The GuideLine Implementability appraisal (GLIA): development of an instrument to identify obstacles to guideline implementation. BMC Med Inform Decis Mak. 2005;5:23.CrossRefPubMedPubMedCentral Shiffman RN, Dixon J, Brandt C, Essaihi A, Hsiao A, Michel G, et al. The GuideLine Implementability appraisal (GLIA): development of an instrument to identify obstacles to guideline implementation. BMC Med Inform Decis Mak. 2005;5:23.CrossRefPubMedPubMedCentral
47.
go back to reference Joffe H, Yardley L. Content and thematic analysis. In: Marks DF, Yardley L, editors. Research methods for clinical and health psychology. Great Britain: Sage Publications Ltd; 2004. p. 56–66. Joffe H, Yardley L. Content and thematic analysis. In: Marks DF, Yardley L, editors. Research methods for clinical and health psychology. Great Britain: Sage Publications Ltd; 2004. p. 56–66.
48.
go back to reference Diamond IR, Grant RC, Feldman BM, Pencharz PB, Ling SC, Moore AM, et al. Defining consensus: a systematic review recommends methodologic criteria for reporting of Delphi studies. J Clin Epidemiol. 2014;67:401–9.CrossRefPubMed Diamond IR, Grant RC, Feldman BM, Pencharz PB, Ling SC, Moore AM, et al. Defining consensus: a systematic review recommends methodologic criteria for reporting of Delphi studies. J Clin Epidemiol. 2014;67:401–9.CrossRefPubMed
49.
go back to reference Straus S, Haynes RB. Managing evidence-based knowledge: the need for reliable, relevant and readable resources. Can Med Assoc J. 2009;180:942–5.CrossRef Straus S, Haynes RB. Managing evidence-based knowledge: the need for reliable, relevant and readable resources. Can Med Assoc J. 2009;180:942–5.CrossRef
51.
go back to reference Michie S, Lester K. Words matter: increasing the implementation of clinical guidelines. Qual Safety Health. 2005;14:367–70.CrossRef Michie S, Lester K. Words matter: increasing the implementation of clinical guidelines. Qual Safety Health. 2005;14:367–70.CrossRef
52.
go back to reference Borneman T, Koczywas M, Sun V, Piper BF, Smith-Idell C, Laroya B, et al. Effectiveness of a clinical intervention to eliminate barriers to pain and fatigue management in oncology. J Palliat Med. 2011;14:197–205.CrossRefPubMedPubMedCentral Borneman T, Koczywas M, Sun V, Piper BF, Smith-Idell C, Laroya B, et al. Effectiveness of a clinical intervention to eliminate barriers to pain and fatigue management in oncology. J Palliat Med. 2011;14:197–205.CrossRefPubMedPubMedCentral
53.
go back to reference Grol R, Dalhuijsen J, Thomas S, Veld C, Rutten G, Mokkink H. Attributes of clinical guidelines that influence use of guidelines in general practice: observational study. BMJ. 1998;317:858–61.CrossRefPubMedPubMedCentral Grol R, Dalhuijsen J, Thomas S, Veld C, Rutten G, Mokkink H. Attributes of clinical guidelines that influence use of guidelines in general practice: observational study. BMJ. 1998;317:858–61.CrossRefPubMedPubMedCentral
54.
go back to reference Dilworth S, Higgins I, Parker V, Kelly B, Turner J. Patient and health professional's perceived barriers to the delivery of psychosocial care to adults with cancer: a systematic review. Psycho-Oncol. 2014;23:601–12.CrossRef Dilworth S, Higgins I, Parker V, Kelly B, Turner J. Patient and health professional's perceived barriers to the delivery of psychosocial care to adults with cancer: a systematic review. Psycho-Oncol. 2014;23:601–12.CrossRef
55.
go back to reference Fitch MI, Mings D, Lee A. Exploring patient experiences and self-initiated strategies for living with cancer-related fatigue. Can Oncol Nurs J. 2008;18:124–40.CrossRefPubMed Fitch MI, Mings D, Lee A. Exploring patient experiences and self-initiated strategies for living with cancer-related fatigue. Can Oncol Nurs J. 2008;18:124–40.CrossRefPubMed
56.
go back to reference Escalante CP, Kallen MA, Valdres RU, Morrow PK, Manzullo EF. Outcomes of a cancer-related fatigue clinic in a comprehensive cancer center. J Pain Symptom Manag. 2010;39:691–701.CrossRef Escalante CP, Kallen MA, Valdres RU, Morrow PK, Manzullo EF. Outcomes of a cancer-related fatigue clinic in a comprehensive cancer center. J Pain Symptom Manag. 2010;39:691–701.CrossRef
57.
go back to reference de Raaf PJ, de Klerk C, Timman R, Busschbach JJ, Oldenmenger WH, van der Rijt CD. Systematic monitoring and treatment of physical symptoms to alleviate fatigue in patients with advanced cancer: a randomized controlled trial. J Clin Oncol. 2013;31:716–23.CrossRefPubMed de Raaf PJ, de Klerk C, Timman R, Busschbach JJ, Oldenmenger WH, van der Rijt CD. Systematic monitoring and treatment of physical symptoms to alleviate fatigue in patients with advanced cancer: a randomized controlled trial. J Clin Oncol. 2013;31:716–23.CrossRefPubMed
58.
go back to reference Craig P, Dieppe P, Macintyre S, Michie S, Nazareth I, Petticrew M. Developing and evaluating complex interventions: the new Medical Research Council guidance. BMJ. 2008;337:a1655.CrossRefPubMedPubMedCentral Craig P, Dieppe P, Macintyre S, Michie S, Nazareth I, Petticrew M. Developing and evaluating complex interventions: the new Medical Research Council guidance. BMJ. 2008;337:a1655.CrossRefPubMedPubMedCentral
59.
go back to reference Green CA, Duan N, Gibbons RD, Hoagwood KE, Palinkas LA, Wisdom JP. Approaches to mixed methods dissemination and implementation research: methods, strengths, caveats, and opportunities. Adm Policy Ment Health. 2015;42:508–23.CrossRefPubMedPubMedCentral Green CA, Duan N, Gibbons RD, Hoagwood KE, Palinkas LA, Wisdom JP. Approaches to mixed methods dissemination and implementation research: methods, strengths, caveats, and opportunities. Adm Policy Ment Health. 2015;42:508–23.CrossRefPubMedPubMedCentral
Metadata
Title
Cancer related fatigue: implementing guidelines for optimal management
Authors
Elizabeth J. M. Pearson
Meg E. Morris
Carol E. McKinstry
Publication date
01-12-2017
Publisher
BioMed Central
Published in
BMC Health Services Research / Issue 1/2017
Electronic ISSN: 1472-6963
DOI
https://doi.org/10.1186/s12913-017-2415-9

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