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BMC Dermatology
Published in: BMC Dermatology 1/2015

Open Access 01-12-2015 | Case report

Small lymphocytic lymphoma with florid perniosis-like features: a case report

Authors: Taylor M. Morris, Rosetta Mazzola, Brian Berry, Douglas Sawyer, David L. Saltman

Published in: BMC Dermatology | Issue 1/2015

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Abstract

Background

Small lymphocytic lymphoma is a relatively rare B-cell non-Hodgkin lymphoma that is considered to be the tissue equivalent of the much more common entity chronic lymphocytic leukemia. Cutaneous manifestations of small lymphocytic lymphoma are infrequent and the literature regarding them sparse. We describe here a case of a patient with a history of small lymphocytic lymphoma who developed perniosis-like features of the digits.

Case presentation

An 86-year old male patient with previously diagnosed small lymphocytic lymphoma developed painful erythematous swelling of the periungual area of his fingers and toes. This was associated with a dense dermal infiltration of CD5-positive B-lymphoid cells consistent with his low-grade B-cell lymphoma. Although partially refractory to local radiotherapy, the painful swelling of the fingers and toes resolved fully following systemic therapy with chlorambucil and rituximab.

Conclusions

This unusual cutaneous manifestation of a lymphoma and the favourable response to systemic therapy may be instructive for the management of other patients who develop similar perniosis-like features.
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Metadata
Title
Small lymphocytic lymphoma with florid perniosis-like features: a case report
Authors
Taylor M. Morris
Rosetta Mazzola
Brian Berry
Douglas Sawyer
David L. Saltman
Publication date
01-12-2015
Publisher
BioMed Central
Published in
BMC Dermatology / Issue 1/2015
Electronic ISSN: 1471-5945
DOI
https://doi.org/10.1186/s12895-015-0032-z

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