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BMC Surgery
Published in: BMC Surgery 1/2015

Open Access 01-12-2015 | Research article

Impact of ABO blood group on the prognosis of patients undergoing surgery for esophageal cancer

Authors: Wei Wang, Lei Liu, Zhiwei Wang, Min Wei, Qi He, Tianlong Ling, Ziang Cao, Yixin Zhang, Qiang Wang, Minxin Shi

Published in: BMC Surgery | Issue 1/2015

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Abstract

Background

ABO blood type is an established prognostic factor in several malignancies, but its role in esophageal cancer (EC) is largely unknown. The aim of this study is to determine whether ABO blood group is associated with survival after esophagectomy for EC.

Methods

A total of 406 patients who underwent surgery for EC were enrolled. The associations of ABO blood group with clinical and pathological variables were assessed using chi-square test. Associations of ABO blood group with the survival were estimated using univariable and multivariable Cox proportional hazards regression models.

Results

The ABO blood group proportionally associated with the grade of EC tumor (P = 0.049). The ABO blood group status did not correlate with disease-free survival (DFS) in univariable analysis or multivariable analysis (P > 0.05). And there was no significant relationship between the ABO blood group and overall survival (OS) in univariable analysis or multivariable analysis (P > 0.05).

Conclusions

Our results suggested that no association between ABO blood group and the survival was observed in patients undergoing surgery for EC.
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Metadata
Title
Impact of ABO blood group on the prognosis of patients undergoing surgery for esophageal cancer
Authors
Wei Wang
Lei Liu
Zhiwei Wang
Min Wei
Qi He
Tianlong Ling
Ziang Cao
Yixin Zhang
Qiang Wang
Minxin Shi
Publication date
01-12-2015
Publisher
BioMed Central
Published in
BMC Surgery / Issue 1/2015
Electronic ISSN: 1471-2482
DOI
https://doi.org/10.1186/s12893-015-0094-1

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