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Published in: BMC Pulmonary Medicine 1/2018

Open Access 01-12-2018 | Research article

Guideline adherence in hospital recruited and population based COPD patients

Authors: Bahareh Jouleh, Marta Erdal, Tomas Mikal Eagan, Per Bakke, Amund Gulsvik, Rune Nielsen

Published in: BMC Pulmonary Medicine | Issue 1/2018

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Abstract

Background

Evidence from several studies show poor guideline adherence to COPD treatment, but no such study has been undertaken in Norway. The objectives of this study, was to estimate and compare the guideline adherence to COPD treatment in general population-based and hospital-recruited COPD patients, and find possible predictors of guideline adherence.

Methods

From the prospective, observational EconCOPD-study, we analysed guideline adherence for 90 population-based COPD cases compared to 245 hospital-recruited COPD patients. Overall guideline adherence was defined as correct pharmacological treatment, and influenza vaccination the preceding year, and having received smoking cessation advice. Multivariate logistic regression analysis was performed with the dichotomous outcome overall guideline adherence adjusting for relevant variables.

Results

The overall guideline adherence for population-based COPD cases was 6.7%, significantly lower than the 29.8% overall guideline-adherence amongst hospital-recruited COPD patients. Adherence to pharmacological treatment guidelines was 10.0 and 35.5%, for the two recruitment sources, respectively. GOLD-stage 3 to 4 was associated with significantly better guideline adherence compared to GOLD-stage 2 (OR (95% CI) 18.9 (8.37,42.7)). The unadjusted difference between the two recruitment sources was completely explained by degree of airflow obstruction.

Conclusion

Overall guideline adherence was very low for both recruitment sources. We call for increased attention from authorities and healthcare personnel to improve the quality of care given to this patient group.
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Literature
2.
go back to reference Sullivan SD, Ramsey SD, Lee TA. The economic burden of COPD. Chest. 2000;117(2 Suppl):5S–9S.CrossRef Sullivan SD, Ramsey SD, Lee TA. The economic burden of COPD. Chest. 2000;117(2 Suppl):5S–9S.CrossRef
3.
go back to reference Donaldson GC, et al. Relationship between exacerbation frequency and lung function decline in chronic obstructive pulmonary disease. Thorax. 2002;57(10):847–52.CrossRef Donaldson GC, et al. Relationship between exacerbation frequency and lung function decline in chronic obstructive pulmonary disease. Thorax. 2002;57(10):847–52.CrossRef
4.
go back to reference Halpin DM, et al. Exacerbation frequency and course of COPD. Int J Chron Obstruct Pulmon Dis. 2012;7:653–61.CrossRef Halpin DM, et al. Exacerbation frequency and course of COPD. Int J Chron Obstruct Pulmon Dis. 2012;7:653–61.CrossRef
5.
go back to reference Seemungal TA, et al. Effect of exacerbation on quality of life in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 1998;157(5 Pt 1):1418–22.CrossRef Seemungal TA, et al. Effect of exacerbation on quality of life in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 1998;157(5 Pt 1):1418–22.CrossRef
6.
go back to reference Thomas M, et al. COPD exacerbation frequency, pharmacotherapy and resource use: an observational study in UK primary care. COPD. 2014;11(3):300–9.PubMed Thomas M, et al. COPD exacerbation frequency, pharmacotherapy and resource use: an observational study in UK primary care. COPD. 2014;11(3):300–9.PubMed
7.
go back to reference Wedzicha JA, et al. Mechanisms and impact of the frequent exacerbator phenotype in chronic obstructive pulmonary disease. BMC Med. 2013;11:181.CrossRef Wedzicha JA, et al. Mechanisms and impact of the frequent exacerbator phenotype in chronic obstructive pulmonary disease. BMC Med. 2013;11:181.CrossRef
8.
go back to reference Lokke A, et al. Developing COPD: a 25 year follow up study of the general population. Thorax. 2006;61(11):935–9.CrossRef Lokke A, et al. Developing COPD: a 25 year follow up study of the general population. Thorax. 2006;61(11):935–9.CrossRef
9.
go back to reference Schikowski T, et al. Long-term air pollution exposure and living close to busy roads are associated with COPD in women. Respir Res. 2005;6:152.CrossRef Schikowski T, et al. Long-term air pollution exposure and living close to busy roads are associated with COPD in women. Respir Res. 2005;6:152.CrossRef
10.
go back to reference Oxman AD, et al. Occupational dust exposure and chronic obstructive pulmonary disease. A systematic overview of the evidence. Am Rev Respir Dis. 1993;148(1):38–48.CrossRef Oxman AD, et al. Occupational dust exposure and chronic obstructive pulmonary disease. A systematic overview of the evidence. Am Rev Respir Dis. 1993;148(1):38–48.CrossRef
11.
go back to reference Sunyer J, et al. Lung function decline, chronic bronchitis, and occupational exposures in young adults. Am J Respir Crit Care Med. 2005;172(9):1139–45.CrossRef Sunyer J, et al. Lung function decline, chronic bronchitis, and occupational exposures in young adults. Am J Respir Crit Care Med. 2005;172(9):1139–45.CrossRef
12.
go back to reference Corrado A, Rossi A. How far is real life from COPD therapy guidelines? An Italian observational study. Respir Med. 2012;106(7):989–97.CrossRef Corrado A, Rossi A. How far is real life from COPD therapy guidelines? An Italian observational study. Respir Med. 2012;106(7):989–97.CrossRef
13.
go back to reference Visentin E, et al. An observation of prescription behaviors and adherence to guidelines in patients with COPD: real world data from October 2012 to September 2014. Curr Med Res Opin. 2016;32(9):1493–502.CrossRef Visentin E, et al. An observation of prescription behaviors and adherence to guidelines in patients with COPD: real world data from October 2012 to September 2014. Curr Med Res Opin. 2016;32(9):1493–502.CrossRef
14.
go back to reference Lopez-Campos JL, et al. Guideline adherence in outpatient clinics for chronic obstructive pulmonary disease: results from a clinical audit. PLoS One. 2016;11(3):e0151896.CrossRef Lopez-Campos JL, et al. Guideline adherence in outpatient clinics for chronic obstructive pulmonary disease: results from a clinical audit. PLoS One. 2016;11(3):e0151896.CrossRef
15.
go back to reference Sen E, et al. Adherence to GOLD guideline treatment recommendations among pulmonologists in Turkey. Int J Chron Obstruct Pulmon Dis. 2015;10:2657–63.CrossRef Sen E, et al. Adherence to GOLD guideline treatment recommendations among pulmonologists in Turkey. Int J Chron Obstruct Pulmon Dis. 2015;10:2657–63.CrossRef
16.
go back to reference Price D, et al. Management of COPD in the UK primary-care setting: an analysis of real-life prescribing patterns. Int J Chron Obstruct Pulmon Dis. 2014;9:889–904.CrossRef Price D, et al. Management of COPD in the UK primary-care setting: an analysis of real-life prescribing patterns. Int J Chron Obstruct Pulmon Dis. 2014;9:889–904.CrossRef
17.
go back to reference Tang CY, et al. Level of adherence to the GOLD strategy document for management of patients admitted to hospital with an acute exacerbation of COPD. Respirology. 2014;19(8):1191–7.CrossRef Tang CY, et al. Level of adherence to the GOLD strategy document for management of patients admitted to hospital with an acute exacerbation of COPD. Respirology. 2014;19(8):1191–7.CrossRef
18.
go back to reference Maio S, et al. COPD management according to old and new GOLD guidelines: an observational study with Italian general practitioners. Curr Med Res Opin. 2014;30(6):1033–42.CrossRef Maio S, et al. COPD management according to old and new GOLD guidelines: an observational study with Italian general practitioners. Curr Med Res Opin. 2014;30(6):1033–42.CrossRef
19.
go back to reference Laniado-Laborin R, et al. Subutilization of COPD guidelines in primary care: a pilot study. J Prim Care Community Health. 2013;4(3):172–6.CrossRef Laniado-Laborin R, et al. Subutilization of COPD guidelines in primary care: a pilot study. J Prim Care Community Health. 2013;4(3):172–6.CrossRef
20.
go back to reference Sarc I, et al. Adherence to treatment guidelines and long-term survival in hospitalized patients with chronic obstructive pulmonary disease. J Eval Clin Pract. 2011;17(4):737–43.CrossRef Sarc I, et al. Adherence to treatment guidelines and long-term survival in hospitalized patients with chronic obstructive pulmonary disease. J Eval Clin Pract. 2011;17(4):737–43.CrossRef
21.
go back to reference Jiang YQ, et al. Impact of adherence to GOLD guidelines on 6-minute walk distance, MRC dyspnea scale score, lung function decline, quality of life, and quality-adjusted life years in a Shanghai suburb. Genet Mol Res. 2015;14(3):8861–70.CrossRef Jiang YQ, et al. Impact of adherence to GOLD guidelines on 6-minute walk distance, MRC dyspnea scale score, lung function decline, quality of life, and quality-adjusted life years in a Shanghai suburb. Genet Mol Res. 2015;14(3):8861–70.CrossRef
22.
go back to reference de Miguel-Diez J, et al. Inappropriate overuse of inhaled corticosteroids for COPD patients: impact on health costs and health status. Lung. 2011;189(3):199–206.CrossRef de Miguel-Diez J, et al. Inappropriate overuse of inhaled corticosteroids for COPD patients: impact on health costs and health status. Lung. 2011;189(3):199–206.CrossRef
24.
go back to reference Lange P, et al. The quality of COPD care in general practice in Denmark: the KVASIMODO study. Prim Care Respir J. 2007;16(3):174–81.CrossRef Lange P, et al. The quality of COPD care in general practice in Denmark: the KVASIMODO study. Prim Care Respir J. 2007;16(3):174–81.CrossRef
25.
go back to reference Roberts CM, et al. European hospital adherence to GOLD recommendations for chronic obstructive pulmonary disease (COPD) exacerbation admissions. Thorax. 2013;68(12):1169–71.CrossRef Roberts CM, et al. European hospital adherence to GOLD recommendations for chronic obstructive pulmonary disease (COPD) exacerbation admissions. Thorax. 2013;68(12):1169–71.CrossRef
26.
go back to reference Bernd L, et al. Determinants of underdiagnosis of COPD in national and international surveys. Chest. 2015;148(4):971–85.CrossRef Bernd L, et al. Determinants of underdiagnosis of COPD in national and international surveys. Chest. 2015;148(4):971–85.CrossRef
27.
go back to reference Belletti D, et al. Results of the CAPPS: COPD--assessment of practice in primary care study. Curr Med Res Opin. 2013;29(8):957–66.CrossRef Belletti D, et al. Results of the CAPPS: COPD--assessment of practice in primary care study. Curr Med Res Opin. 2013;29(8):957–66.CrossRef
28.
go back to reference Sharif R, et al. Guideline adherence in management of stable chronic obstructive pulmonary disease. Respir Med. 2013;107(7):1046–52.CrossRef Sharif R, et al. Guideline adherence in management of stable chronic obstructive pulmonary disease. Respir Med. 2013;107(7):1046–52.CrossRef
29.
go back to reference Desalu OO, et al. Guideline-based COPD management in a resource-limited setting - physicians' understanding, adherence and barriers: a cross-sectional survey of internal and family medicine hospital-based physicians in Nigeria. Prim Care Respir J. 2013;22(1):79–85.CrossRef Desalu OO, et al. Guideline-based COPD management in a resource-limited setting - physicians' understanding, adherence and barriers: a cross-sectional survey of internal and family medicine hospital-based physicians in Nigeria. Prim Care Respir J. 2013;22(1):79–85.CrossRef
30.
go back to reference Aisanov Z, et al. Primary care physician perceptions on the diagnosis and management of chronic obstructive pulmonary disease in diverse regions of the world. Int J Chron Obstruct Pulmon Dis. 2012;7:271–82.PubMedPubMedCentral Aisanov Z, et al. Primary care physician perceptions on the diagnosis and management of chronic obstructive pulmonary disease in diverse regions of the world. Int J Chron Obstruct Pulmon Dis. 2012;7:271–82.PubMedPubMedCentral
31.
go back to reference Perez X, et al. Barriers to adherence to COPD guidelines among primary care providers. Respir Med. 2012;106(3):374–81.CrossRef Perez X, et al. Barriers to adherence to COPD guidelines among primary care providers. Respir Med. 2012;106(3):374–81.CrossRef
32.
go back to reference Nielsen R, Klemmetsby M, Gulsvik A. Economics of COPD: literature review and experiences from field work. Clin Respir J. 2008;2(Suppl 1):104–10.CrossRef Nielsen R, Klemmetsby M, Gulsvik A. Economics of COPD: literature review and experiences from field work. Clin Respir J. 2008;2(Suppl 1):104–10.CrossRef
33.
go back to reference Johannessen A, et al. Implications of reversibility testing on prevalence and risk factors for chronic obstructive pulmonary disease: a community study. Thorax. 2005;60(10):842–7.CrossRef Johannessen A, et al. Implications of reversibility testing on prevalence and risk factors for chronic obstructive pulmonary disease: a community study. Thorax. 2005;60(10):842–7.CrossRef
34.
go back to reference ATS. Standardization of spirometry, 1994 Update. American Thoracic Society. Am J Respir Crit Care Med. 1995;152:1107–36. ATS. Standardization of spirometry, 1994 Update. American Thoracic Society. Am J Respir Crit Care Med. 1995;152:1107–36.
35.
go back to reference Gulsvik A, et al. Expiratory and inspiratory forced vital capacity and one-second forced volume in asymptomatic never-smokers in Norway. Clin Physiol. 2001;21(6):648–60.CrossRef Gulsvik A, et al. Expiratory and inspiratory forced vital capacity and one-second forced volume in asymptomatic never-smokers in Norway. Clin Physiol. 2001;21(6):648–60.CrossRef
36.
go back to reference Charlson ME, et al. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis. 1987;40(5):373–83.CrossRef Charlson ME, et al. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis. 1987;40(5):373–83.CrossRef
37.
go back to reference Pauwels RA, et al. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease. NHLBI/WHO global initiative for chronic obstructive lung disease (GOLD) workshop summary. Am J Respir Crit Care Med. 2001;163(5):1256–76.CrossRef Pauwels RA, et al. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease. NHLBI/WHO global initiative for chronic obstructive lung disease (GOLD) workshop summary. Am J Respir Crit Care Med. 2001;163(5):1256–76.CrossRef
38.
go back to reference Maddocks M, et al. Physical frailty and pulmonary rehabilitation in COPD: a prospective cohort study. Thorax. 2016;71(11):988–95.CrossRef Maddocks M, et al. Physical frailty and pulmonary rehabilitation in COPD: a prospective cohort study. Thorax. 2016;71(11):988–95.CrossRef
39.
go back to reference McCarthy B, et al. Pulmonary rehabilitation for chronic obstructive pulmonary disease. Cochrane Database Syst Rev. 2015;2:CD003793. McCarthy B, et al. Pulmonary rehabilitation for chronic obstructive pulmonary disease. Cochrane Database Syst Rev. 2015;2:CD003793.
40.
go back to reference Sandelowsky H, et al. COPD management by Swedish general practitioners - baseline results of the PRIMAIR study. Scand J Prim Health Care. 2018:1–9. Sandelowsky H, et al. COPD management by Swedish general practitioners - baseline results of the PRIMAIR study. Scand J Prim Health Care. 2018:1–9.
41.
go back to reference Drivenes E, Ostrem A, Melbye H. Predictors of ICS/LABA prescribing in COPD patients: a study from general practice. BMC Fam Pract. 2014;15:42.CrossRef Drivenes E, Ostrem A, Melbye H. Predictors of ICS/LABA prescribing in COPD patients: a study from general practice. BMC Fam Pract. 2014;15:42.CrossRef
42.
go back to reference Laue J, Reierth E, Melbye H. When should acute exacerbations of COPD be treated with systemic corticosteroids and antibiotics in primary care: a systematic review of current COPD guidelines. NPJ Prim Care Respir Med. 2015;25:15002.CrossRef Laue J, Reierth E, Melbye H. When should acute exacerbations of COPD be treated with systemic corticosteroids and antibiotics in primary care: a systematic review of current COPD guidelines. NPJ Prim Care Respir Med. 2015;25:15002.CrossRef
43.
go back to reference Volla TT, Kopperud G. Vedlikeholdsbehandling av kronisk obstruktiv lungesykdom. Tidsskriftet for den norske legeforening; 2008. Volla TT, Kopperud G. Vedlikeholdsbehandling av kronisk obstruktiv lungesykdom. Tidsskriftet for den norske legeforening; 2008.
44.
go back to reference Medisin D. Myndighetene tar ikke ansvar; 2015. Medisin D. Myndighetene tar ikke ansvar; 2015.
45.
go back to reference Nielsen R. Costs of chronic obstructive pulmonary disease in a general population. Methodological aspects and longitudinal perspectives (dissertation); 2011. Nielsen R. Costs of chronic obstructive pulmonary disease in a general population. Methodological aspects and longitudinal perspectives (dissertation); 2011.
46.
go back to reference Nielsen R, et al. Excessive costs of COPD in ever-smokers. A longitudinal community study. Respir Med. 2011;105(3):485–93.CrossRef Nielsen R, et al. Excessive costs of COPD in ever-smokers. A longitudinal community study. Respir Med. 2011;105(3):485–93.CrossRef
Metadata
Title
Guideline adherence in hospital recruited and population based COPD patients
Authors
Bahareh Jouleh
Marta Erdal
Tomas Mikal Eagan
Per Bakke
Amund Gulsvik
Rune Nielsen
Publication date
01-12-2018
Publisher
BioMed Central
Published in
BMC Pulmonary Medicine / Issue 1/2018
Electronic ISSN: 1471-2466
DOI
https://doi.org/10.1186/s12890-018-0756-8

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