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BMC Pregnancy and Childbirth
Published in: BMC Pregnancy and Childbirth 1/2020

Open Access 01-12-2020 | Miscarriage | Research article

The impact of TSH levels on clinical outcomes 14 days after frozen-thawed embryo transfer

Authors: Yuchao Zhang, Wenbin Wu, Yanli Liu, Yichun Guan, Xingling Wang, Liting Jia

Published in: BMC Pregnancy and Childbirth | Issue 1/2020

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Abstract

Background

The aim of this study was to investigate the impact of TSH levels on clinical outcomes 14 days after frozen-thawed embryo transfer.

Methods

Blood samples were collected on the first visit to our department and 14 days after embryo transfer. Women were divided into three groups based on D14 TSH levels, which were compared to basal TSH levels in groups with different clinical outcomes. TSH levels between pregnant and nonpregnant women were also compared.

Results

The clinical pregnancy rate in women with lower TSH levels 14 days after transfer was slightly but significantly lower (56%, P = 0.05) compared to those with higher TSH levels. Furthermore, TSH levels were significantly elevated 14 days after transfer compared to basal TSH levels in pregnant women and in women who successfully became pregnant (P < 0.001, respectively).

Conclusions

Elevated TSH levels 14 days after embryo transfer compared to basal TSH levels seem to play a protective role and predict favorable clinical outcomes under specific conditions.
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Metadata
Title
The impact of TSH levels on clinical outcomes 14 days after frozen-thawed embryo transfer
Authors
Yuchao Zhang
Wenbin Wu
Yanli Liu
Yichun Guan
Xingling Wang
Liting Jia
Publication date
01-12-2020
Publisher
BioMed Central
Published in
BMC Pregnancy and Childbirth / Issue 1/2020
Electronic ISSN: 1471-2393
DOI
https://doi.org/10.1186/s12884-020-03383-z

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