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Published in: BMC Neurology 1/2018

Open Access 01-12-2018 | Research article

Migraine-related disability and co-morbid depression among migraineurs in Ethiopia: a cross-sectional study

Authors: Biniyam Alemayehu Ayele, Yared Mamushet Yifru

Published in: BMC Neurology | Issue 1/2018

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Abstract

Background

Migraine headache is a neurologic disorder which mainly affects younger and productive segment of population. Migraine not only causes pain; but also affects quality of life in terms of low productivity and economic loss. The main aim of this study was to examine migraine-related disability, co-morbid depression, and relationship between the two.

Methods

A cross-sectional study was conducted among migraineurs who visited two neurology referral clinics. The study was conducted between June 1st 2016 to December 30th2016. Migraine disability assessment score [MIDAS] and patient health questionnaire [PHQ-9] were used to assess disability and depression, respectively.

Results

A total of 70 patients participated in the study. Fifty-three (74.3%) of our study participants were women. Fifty one (72.9%) study participants were between age group 20–40 years. Migraine without aura was the most common subtype (70%); migraine with aura accounted for the other 28.6%. The mean (± SD) headache frequency and intensity was 23.4 ± 14.9 days and 7.4 ± 1.2 respectively. Major depressive disorder was common in this group (41.4%). The mean MIDAS and PHQ-9 scores were 46.7 ± 30 and 9.2 ± 4.4 respectively. More than two-thirds (74.3%) of our participants had severe disability. We found a statistically significant correlation between migraine-related disability and co morbid depression among our participants(r = 0.318, p-value = 0.007).

Conclusion

The positive correlation observed between migraine-related disability and co-morbid depression warrant routine screening and treatment of disability and depression in migraineurs; In addition, the observed high degree of disability among our participants may indicate sub optimal treatment of these patients.
Literature
1.
go back to reference L. M. Bloudek, M. Stokes, D., C. Buse,T. K. Wilcox, R. B. Lipton, P. J. Goadsby,S. F. Varon, A. M. Blumenfeld, Z. KatsaravaJ. Pascual, M. Lanteri-Minet, P. Cortelli, P. Martelletti et al. cost of healthcare for patients with migraine in five European countries- results from the international burden of migraine study (IBMS). J Headache Pain.2012; 13:361–378. L. M. Bloudek, M. Stokes, D., C. Buse,T. K. Wilcox, R. B. Lipton, P. J. Goadsby,S. F. Varon, A. M. Blumenfeld, Z. KatsaravaJ. Pascual, M. Lanteri-Minet, P. Cortelli, P. Martelletti et al. cost of healthcare for patients with migraine in five European countries- results from the international burden of migraine study (IBMS). J Headache Pain.2012; 13:361–378.
2.
go back to reference Robert BD, Joseph J, John CM, Scott LP. Headache and other craniofacial pain. In: Ivan G, Todd JS, Carrie ER, Jonathan HS, editors. Bradely, Neurology in clinical practice. 7th ed. China: Elsevier; 2016. p. 1695–706. Robert BD, Joseph J, John CM, Scott LP. Headache and other craniofacial pain. In: Ivan G, Todd JS, Carrie ER, Jonathan HS, editors. Bradely, Neurology in clinical practice. 7th ed. China: Elsevier; 2016. p. 1695–706.
3.
go back to reference Vos T, Flaxman AD, Naghavi M, Lozano R, Michaud C, Ezzati M, Shibuya K, Salomon JA, Abdalla S, Aboyans V, Abraham J, Ackerman I, Aggarwal R, Ahn SY, Ali MK, Alvarado M, Anderson HR, Anderson LM, Andrews KG, Atkinson C, Baddour LM, Bahalim AN, Barker-Collo S, Barrero LH, Bartels DH, Basáñez MG, Baxter A, Bell ML, Benjamin EJ, Bennett D, et al. Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990–2010: a systematic analysis for the global burden of disease study 2010. Lancet. 2012;380:2163–96.CrossRefPubMed Vos T, Flaxman AD, Naghavi M, Lozano R, Michaud C, Ezzati M, Shibuya K, Salomon JA, Abdalla S, Aboyans V, Abraham J, Ackerman I, Aggarwal R, Ahn SY, Ali MK, Alvarado M, Anderson HR, Anderson LM, Andrews KG, Atkinson C, Baddour LM, Bahalim AN, Barker-Collo S, Barrero LH, Bartels DH, Basáñez MG, Baxter A, Bell ML, Benjamin EJ, Bennett D, et al. Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990–2010: a systematic analysis for the global burden of disease study 2010. Lancet. 2012;380:2163–96.CrossRefPubMed
4.
go back to reference Castillo J, Munoz P, Guitera V, et al. Epidemiology of chronic daily headache in the general population. Headache. 1998;39:190–6.CrossRef Castillo J, Munoz P, Guitera V, et al. Epidemiology of chronic daily headache in the general population. Headache. 1998;39:190–6.CrossRef
5.
go back to reference ICDH. The International Classification of Headache Disorders: 3rd edition. Cephalalgia. 2013;33(9):629–808.CrossRef ICDH. The International Classification of Headache Disorders: 3rd edition. Cephalalgia. 2013;33(9):629–808.CrossRef
9.
go back to reference Leonardi M, Steiner TJ, Scher AT, Lipton RB, et al. The global burden of migraine-measuring disability in headache disorders with WHO’s classification of functioning, disability and health (ICF). J Headache Pain. 2005;6:429–40.CrossRefPubMedPubMedCentral Leonardi M, Steiner TJ, Scher AT, Lipton RB, et al. The global burden of migraine-measuring disability in headache disorders with WHO’s classification of functioning, disability and health (ICF). J Headache Pain. 2005;6:429–40.CrossRefPubMedPubMedCentral
10.
go back to reference World Health Organization. Atlas of Headache Disorders and Resources in the World. Geneva: World Health Organization; 2011. www.who.int. ISBN 978 924 15642 12. World Health Organization. Atlas of Headache Disorders and Resources in the World. Geneva: World Health Organization; 2011. www.​who.​int. ISBN 978 924 15642 12.
12.
go back to reference Mercante JP, Peres MF, Vera G, Eliova Z, Marcio AB, et al. DEPRESSION IN CHRONIC MIGRAINE. ArqNeuropsiquiatr. 2005;63(2):217–20. Mercante JP, Peres MF, Vera G, Eliova Z, Marcio AB, et al. DEPRESSION IN CHRONIC MIGRAINE. ArqNeuropsiquiatr. 2005;63(2):217–20.
13.
go back to reference Breslau N, Lipton RB, et al. Co morbidity of migraine and depression. Neurology. 2003;60:1308–12.CrossRefPubMed Breslau N, Lipton RB, et al. Co morbidity of migraine and depression. Neurology. 2003;60:1308–12.CrossRefPubMed
14.
go back to reference Breslau N, Davis GC, et al. Migraine and major depression – a longitudinal study. HEADACHE J HEAD AND FACE PAIN. 1994;34:387–93.CrossRef Breslau N, Davis GC, et al. Migraine and major depression – a longitudinal study. HEADACHE J HEAD AND FACE PAIN. 1994;34:387–93.CrossRef
15.
go back to reference Jette N., et al. Comorbidity of migraine and psychiatric disorders - a national population-based study. Headache 2008;48; 4: 501–16. Jette N., et al. Comorbidity of migraine and psychiatric disorders - a national population-based study. Headache 2008;48; 4: 501–16.
16.
go back to reference Shehbaz N, Ali S, et al. MIGRAINE - COMORBIDITY WITH DEPRESSION. Pak J Med Sci. 2007;23(1):95–9. Shehbaz N, Ali S, et al. MIGRAINE - COMORBIDITY WITH DEPRESSION. Pak J Med Sci. 2007;23(1):95–9.
17.
go back to reference Stewart WF, et al. Reliability of the migraine disability assessment score in a population based sample of headache sufferers. Cephalalgia. 1999;19(2):107–14.CrossRefPubMed Stewart WF, et al. Reliability of the migraine disability assessment score in a population based sample of headache sufferers. Cephalalgia. 1999;19(2):107–14.CrossRefPubMed
18.
go back to reference Monahan PO, Shacham E, Reece M, et al. Validity/reliability of PHQ-9 and PHQ-2 depression scales among adults living with HIV/AIDS in western Kenya. J Gen Intern Med. 2009;24:189–97.CrossRefPubMed Monahan PO, Shacham E, Reece M, et al. Validity/reliability of PHQ-9 and PHQ-2 depression scales among adults living with HIV/AIDS in western Kenya. J Gen Intern Med. 2009;24:189–97.CrossRefPubMed
19.
go back to reference Omoro SA, Fann JR, Weymuller EA, Macharia IM, Yueh B, et al. Swahili translation and validation of the patient health Questionnaire-9 depression scale in the Kenyan head and neck cancer patient population. Int J Psychiatry Med. 2006;36:367–81.CrossRefPubMed Omoro SA, Fann JR, Weymuller EA, Macharia IM, Yueh B, et al. Swahili translation and validation of the patient health Questionnaire-9 depression scale in the Kenyan head and neck cancer patient population. Int J Psychiatry Med. 2006;36:367–81.CrossRefPubMed
20.
go back to reference Charlotte H, Girmay M, Medhin S, et al. Validity of brief screening questionnaires to detect depression in primary care in Ethiopia. J Affect Disord. 2015;186:32–9.CrossRef Charlotte H, Girmay M, Medhin S, et al. Validity of brief screening questionnaires to detect depression in primary care in Ethiopia. J Affect Disord. 2015;186:32–9.CrossRef
21.
go back to reference Gobel H, Petersen-Braun M, Soyka D, et al. The epidemiology of headache in Germany - a nationwide survey of a representative sample on the basis of the headache classification of the international headache society. Cephalalgia. 1994;14:97–106.CrossRefPubMed Gobel H, Petersen-Braun M, Soyka D, et al. The epidemiology of headache in Germany - a nationwide survey of a representative sample on the basis of the headache classification of the international headache society. Cephalalgia. 1994;14:97–106.CrossRefPubMed
23.
25.
go back to reference Amoozegar F, et al. The prevalence of depression and the accuracy of depression screening tools in migraine patients. Report. Univeristy of Calgary. Alberta APRIL. 2014. Amoozegar F, et al. The prevalence of depression and the accuracy of depression screening tools in migraine patients. Report. Univeristy of Calgary. Alberta APRIL. 2014.
27.
go back to reference Eraslan D, Dikmen PY, et al. The relation of sexual function to migraine-related disability, depression and anxiety in patients with migraine. J Headache Pain. 2014;15:32.CrossRefPubMedPubMedCentral Eraslan D, Dikmen PY, et al. The relation of sexual function to migraine-related disability, depression and anxiety in patients with migraine. J Headache Pain. 2014;15:32.CrossRefPubMedPubMedCentral
28.
go back to reference CORALLO F COLAMC, et al. Assessment of anxiety, depressive disorders and pain intensity in migraine and tension headache patients. ActaMedicaMediterranea. 2015;31:615. CORALLO F COLAMC, et al. Assessment of anxiety, depressive disorders and pain intensity in migraine and tension headache patients. ActaMedicaMediterranea. 2015;31:615.
29.
go back to reference Kim SY, Park SP, et al. The role of headache chronicity among predictors contributing to quality of life in patients with migraine - a hospital-based study. J Headache Pain. 2014;15:68.CrossRefPubMedPubMedCentral Kim SY, Park SP, et al. The role of headache chronicity among predictors contributing to quality of life in patients with migraine - a hospital-based study. J Headache Pain. 2014;15:68.CrossRefPubMedPubMedCentral
30.
go back to reference J l B, Roberson SC, et al. The relationship between co-morbid depression and migraine disability. Advanced studies in medicine. 2002;2:16. J l B, Roberson SC, et al. The relationship between co-morbid depression and migraine disability. Advanced studies in medicine. 2002;2:16.
Metadata
Title
Migraine-related disability and co-morbid depression among migraineurs in Ethiopia: a cross-sectional study
Authors
Biniyam Alemayehu Ayele
Yared Mamushet Yifru
Publication date
01-12-2018
Publisher
BioMed Central
Published in
BMC Neurology / Issue 1/2018
Electronic ISSN: 1471-2377
DOI
https://doi.org/10.1186/s12883-018-1095-3

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