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BMC Nephrology

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Open Access 01-12-2022 | Acute Kidney Injury | Research

The incidence, risk factors and outcomes of acute kidney injury in critically ill patients undergoing emergency surgery: a prospective observational study

Authors: Linhui Hu, Lu Gao, Danqing Zhang, Yating Hou, Lin Ling He, Huidan Zhang, Yufan Liang, Jing Xu, Chunbo Chen

Published in: BMC Nephrology | Issue 1/2022

Abstract

Background

Without sufficient evidence in postoperative acute kidney injury (AKI) in critically ill patients undergoing emergency surgery, it is meaningful to explore the incidence, risk factors, and prognosis of postoperative AKI.

Methods

A prospective observational study was conducted in the general intensive care units (ICUs) from January 2014 to March 2018. Variables about preoperation, intraoperation and postoperation were collected. AKI was diagnosed using the Kidney Disease: Improving Global Outcomes criteria.

Results

Among 383 critically ill patients undergoing emergency surgery, 151 (39.4%) patients developed postoperative AKI. Postoperative reoperation, postoperative Acute Physiology and Chronic Health Evaluation (APACHE II) score, and postoperative serum lactic acid (LAC) were independent risk factors for postoperative AKI, with the adjusted odds ratio (ORadj) of 1.854 (95% confidence interval [CI], 1.091–3.152), 1.059 (95%CI, 1.018–1.102), and 1.239 (95%CI, 1.047–1.467), respectively. Compared with the non-AKI group, duration of mechanical ventilation, renal replacement therapy, ICU and hospital mortality, ICU and hospital length of stay, total ICU and hospital costs were higher in the AKI group.

Conclusions

Postoperative reoperation, postoperative APACHE II score, and postoperative LAC were independent risk factors of postoperative AKI in critically ill patients undergoing emergency surgery.

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Title: The incidence, risk factors and outcomes of acute kidney injury in critically ill patients undergoing emergency surgery: a prospective observational study
Authors: Linhui Hu
Lu Gao
Danqing Zhang
Yating Hou
Lin Ling He
Huidan Zhang
Yufan Liang
Jing Xu
Chunbo Chen
Publication date: 01-12-2022
Publisher: BioMed Central
Keywords: Acute Kidney Injury
Acute Kidney Injury
Published in: BMC Nephrology / Issue 1/2022
Electronic ISSN: 1471-2369
DOI: https://doi.org/10.1186/s12882-022-02675-0

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The incidence, risk factors and outcomes of acute kidney injury in critically ill patients undergoing emergency surgery: a prospective observational study

Abstract

Background

Methods

Results

Conclusions

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Abstract

Background

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Conclusions

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