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Published in: BMC Infectious Diseases 1/2022

Open Access 01-12-2022 | COVID-19 | Research

Preventing COVID-19 outbreaks through surveillance testing in healthcare facilities: a modelling study

Authors: Tim Litwin, Jens Timmer, Mathias Berger, Andreas Wahl-Kordon, Matthias J. Müller, Clemens Kreutz

Published in: BMC Infectious Diseases | Issue 1/2022

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Abstract

Background

Surveillance testing within healthcare facilities provides an opportunity to prevent severe outbreaks of coronavirus disease 2019 (COVID-19). However, the quantitative impact of different available surveillance strategies and their potential to decrease the frequency of outbreaks are not well-understood.

Methods

We establish an individual-based model representative of a mental health hospital yielding generalizable results. Attributes and features of this facility were derived from a prototypical hospital, which provides psychiatric, psychosomatic and psychotherapeutic treatment. We estimate the relative reduction of outbreak probability for three test strategies (entry test, once-weekly test and twice-weekly test) relative to a symptom-based baseline strategy. Based on our findings, we propose determinants of successful surveillance measures.

Results

Entry Testing reduced the outbreak probability by 26%, additionally testing once or twice weekly reduced the outbreak probability by 49% or 67% respectively. We found that fast diagnostic test results and adequate compliance of the clinic population are mandatory for conducting effective surveillance. The robustness of these results towards uncertainties is demonstrated via comprehensive sensitivity analyses.

Conclusions

We conclude that active testing in mental health hospitals and similar facilities considerably reduces the number of COVID-19 outbreaks compared to symptom-based surveillance only.
Appendix
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Metadata
Title
Preventing COVID-19 outbreaks through surveillance testing in healthcare facilities: a modelling study
Authors
Tim Litwin
Jens Timmer
Mathias Berger
Andreas Wahl-Kordon
Matthias J. Müller
Clemens Kreutz
Publication date
01-12-2022
Publisher
BioMed Central
Keyword
COVID-19
Published in
BMC Infectious Diseases / Issue 1/2022
Electronic ISSN: 1471-2334
DOI
https://doi.org/10.1186/s12879-022-07075-1

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