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Open Access 01-12-2021 | Antibiotic | Research article

Incidence, healthcare-seeking behaviours, antibiotic use and natural history of common infection syndromes in England: results from the Bug Watch community cohort study

Authors: Catherine M. Smith, Laura J. Shallcross, Peter Dutey-Magni, Anne Conolly, Christopher Fuller, Suzanne Hill, Arnoupe Jhass, Franziska Marcheselli, Susan Michie, Jennifer S. Mindell, Matthew J. Ridd, Georgios Tsakos, Andrew C. Hayward, Ellen B. Fragaszy, on behalf of the PASS research group

Published in: BMC Infectious Diseases | Issue 1/2021

Abstract

Background

Better information on the typical course and management of acute common infections in the community could inform antibiotic stewardship campaigns. We aimed to investigate the incidence, management, and natural history of a range of infection syndromes (respiratory, gastrointestinal, mouth/dental, skin/soft tissue, urinary tract, and eye).

Methods

Bug Watch was an online prospective community cohort study of the general population in England (2018–2019) with weekly symptom reporting for 6 months. We combined symptom reports into infection syndromes, calculated incidence rates, described the proportion leading to healthcare-seeking behaviours and antibiotic use, and estimated duration and severity.

Results

The cohort comprised 873 individuals with 23,111 person-weeks follow-up. The mean age was 54 years and 528 (60%) were female. We identified 1422 infection syndromes, comprising 40,590 symptom reports. The incidence of respiratory tract infection syndromes was two per person year; for all other categories it was less than one. 194/1422 (14%) syndromes led to GP (or dentist) consultation and 136/1422 (10%) to antibiotic use. Symptoms usually resolved within a week and the third day was the most severe.

Conclusions

Most people reported managing their symptoms without medical consultation. Interventions encouraging safe self-management across a range of acute infection syndromes could decrease pressure on primary healthcare services and support targets for reducing antibiotic prescribing.

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Title: Incidence, healthcare-seeking behaviours, antibiotic use and natural history of common infection syndromes in England: results from the Bug Watch community cohort study
Authors: Catherine M. Smith
Laura J. Shallcross
Peter Dutey-Magni
Anne Conolly
Christopher Fuller
Suzanne Hill
Arnoupe Jhass
Franziska Marcheselli
Susan Michie
Jennifer S. Mindell
Matthew J. Ridd
Georgios Tsakos
Andrew C. Hayward
Ellen B. Fragaszy
on behalf of the PASS research group
Publication date: 01-12-2021
Publisher: BioMed Central
Keyword: Antibiotic
Published in: BMC Infectious Diseases / Issue 1/2021
Electronic ISSN: 1471-2334
DOI: https://doi.org/10.1186/s12879-021-05811-7

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Incidence, healthcare-seeking behaviours, antibiotic use and natural history of common infection syndromes in England: results from the Bug Watch community cohort study

Abstract

Background

Methods

Results

Conclusions

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Abstract

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