Skip to main content
Top
Published in: BMC Infectious Diseases 1/2021

Open Access 01-12-2021 | Yersinia Pseudotuberculosis | Case report

Septic shock due to Yersinia pseudotuberculosis infection in an adult immunocompetent patient: a case report and literature review

Authors: Takehiro Hashimoto, Ryuichi Takenaka, Haruka Fukuda, Kazuhiko Hashinaga, Shin-ichi Nureki, Hideki Hayashidani, Teruo Sakamoto, Osamu Shigemitsu

Published in: BMC Infectious Diseases | Issue 1/2021

Login to get access

Abstract

Background

Yersinia pseudotuberculosis infection can occur in an immunocompromised host. Although rare, bacteremia due to Y. pseudotuberculosis may also occur in immunocompetent hosts. The prognosis and therapeutic strategy, especially for immunocompetent patients with Y. pseudotuberculosis bacteremia, however, remains unknown.

Case presentation

A 38-year-old Japanese man with a mood disorder presented to our hospital with fever and diarrhea. Chest computed tomography revealed consolidation in the right upper lobe with air bronchograms. He was diagnosed with pneumonia, and treatment with intravenous ceftriaxone and azithromycin was initiated. The ceftriaxone was replaced with doripenem and the azithromycin was discontinued following the detection of Gram-negative rod bacteria in 2 sets of blood culture tests. The isolated Gram-negative rod bacteria were confirmed to be Y. pseudotuberculosis. Thereafter, he developed septic shock. Doripenem was switched to cefmetazole, which was continued for 14 days. He recovered without relapse.

Conclusions

We herein report a case of septic shock due to Y. pseudotuberculosis infection in an adult immunocompetent patient. The appropriate microorganism tests and antibiotic therapy are necessary to treat patients with Y. pseudotuberculosis bacteremia.
Literature
1.
go back to reference Galindo CL, Rosenzweig JA, Kirtley ML, Chopra AK. Pathogenesis of Y enterocolitica and Y pseudotuberculosis in Human Yersiniosis. J Pathog. 2011;2011:182051.CrossRef Galindo CL, Rosenzweig JA, Kirtley ML, Chopra AK. Pathogenesis of Y enterocolitica and Y pseudotuberculosis in Human Yersiniosis. J Pathog. 2011;2011:182051.CrossRef
2.
go back to reference Kaasch AJ, Dinter J, Goeser T, Plum G, Seifert H. Yersinia pseudotuberculosis bloodstream infection and septic arthritis: case report and review of the literature. Infection. 2012;40(2):185–90.CrossRef Kaasch AJ, Dinter J, Goeser T, Plum G, Seifert H. Yersinia pseudotuberculosis bloodstream infection and septic arthritis: case report and review of the literature. Infection. 2012;40(2):185–90.CrossRef
3.
go back to reference Singer M, Deutschman CS, Seymour CW, Shankar-Hari M, Annane D, Bauer M, Bellomo R, Bernard GR, Chiche JD, Coopersmith CM, et al. The third international consensus definitions for sepsis and septic shock (Sepsis-3). JAMA. 2016;315(8):801–10.CrossRef Singer M, Deutschman CS, Seymour CW, Shankar-Hari M, Annane D, Bauer M, Bellomo R, Bernard GR, Chiche JD, Coopersmith CM, et al. The third international consensus definitions for sepsis and septic shock (Sepsis-3). JAMA. 2016;315(8):801–10.CrossRef
4.
go back to reference Fukushima H, Matsuda Y, Seki R, Tsubokura M, Takeda N, Shubin FN, Paik IK, Zheng XB. Geographical heterogeneity between Far East and Western countries in prevalence of the virulence plasmid, the superantigen Yersinia pseudotuberculosis derived mitogen and the high-pathogenicity island among Yersinia pseudotuberculosis strains. J Clin Microbiol. 2001;39(10):3541–7.CrossRef Fukushima H, Matsuda Y, Seki R, Tsubokura M, Takeda N, Shubin FN, Paik IK, Zheng XB. Geographical heterogeneity between Far East and Western countries in prevalence of the virulence plasmid, the superantigen Yersinia pseudotuberculosis derived mitogen and the high-pathogenicity island among Yersinia pseudotuberculosis strains. J Clin Microbiol. 2001;39(10):3541–7.CrossRef
5.
go back to reference Amphlett A. Far East Scarlet-Like Fever: A Review of the Epidemiology, Symptomatology, and Role of Superantigenic Toxin: Yersinia pseudotuberculosis-Derived Mitogen A. Open Forum Infect Dis. 2015;3(1):ofv202.CrossRef Amphlett A. Far East Scarlet-Like Fever: A Review of the Epidemiology, Symptomatology, and Role of Superantigenic Toxin: Yersinia pseudotuberculosis-Derived Mitogen A. Open Forum Infect Dis. 2015;3(1):ofv202.CrossRef
6.
go back to reference Malassez L, Vignal W. Sur le micro-organisme de la tuberculose zoogloéique. Arch Physiol Norm Pathol. 1884;4:81–104. Malassez L, Vignal W. Sur le micro-organisme de la tuberculose zoogloéique. Arch Physiol Norm Pathol. 1884;4:81–104.
7.
go back to reference Smego RA, Frean J, Koornhof HJ. Yersiniosis I: microbiological and clinicoepidemiological aspects of plague and non-plague Yersinia infections. Eur J Clin Microbiol Infect Dis. 1999;18(1):1–15.CrossRef Smego RA, Frean J, Koornhof HJ. Yersiniosis I: microbiological and clinicoepidemiological aspects of plague and non-plague Yersinia infections. Eur J Clin Microbiol Infect Dis. 1999;18(1):1–15.CrossRef
8.
go back to reference Horinouchi T, Nozu K, Hamahira K, Inaguma Y, Abe J, Nakajima H, Kugo M, Iijima K. Yersinia pseudotuberculosis infection in Kawasaki disease and its clinical characteristics. BMC Pediatr. 2015;15:177.CrossRef Horinouchi T, Nozu K, Hamahira K, Inaguma Y, Abe J, Nakajima H, Kugo M, Iijima K. Yersinia pseudotuberculosis infection in Kawasaki disease and its clinical characteristics. BMC Pediatr. 2015;15:177.CrossRef
9.
go back to reference Vincent P, Leclercq A, Martin L, Duez JM, Simonet M, Carniel E. Sudden onset of pseudotuberculosis in humans, France, 2004-05. Emerg Infect Dis. 2008;14(7):1119–22.CrossRef Vincent P, Leclercq A, Martin L, Duez JM, Simonet M, Carniel E. Sudden onset of pseudotuberculosis in humans, France, 2004-05. Emerg Infect Dis. 2008;14(7):1119–22.CrossRef
10.
go back to reference Mischnik A, Dahme T, Bekeredjian R, Zimmermann S. Haemophilia-associated Yersinia pseudotuberculosis serotype O:1 septicaemia: the role of iron. J Med Microbiol. 2012;61(Pt 1):157–9.CrossRef Mischnik A, Dahme T, Bekeredjian R, Zimmermann S. Haemophilia-associated Yersinia pseudotuberculosis serotype O:1 septicaemia: the role of iron. J Med Microbiol. 2012;61(Pt 1):157–9.CrossRef
11.
go back to reference Bennett J, Dolin R, Blaser M. Mandell, Douglas, and Bennett's principles and practice of infectious diseases 8th Edition; 2014. Bennett J, Dolin R, Blaser M. Mandell, Douglas, and Bennett's principles and practice of infectious diseases 8th Edition; 2014.
12.
go back to reference Ljungberg P, Valtonen M, Harjola VP, Kaukoranta-Tolvanen SS, Vaara M. Report of four cases of Yersinia pseudotuberculosis septicemia and a literature review. Eur J Clin Microbiol Infect Dis. 1995;14(9):804–10.CrossRef Ljungberg P, Valtonen M, Harjola VP, Kaukoranta-Tolvanen SS, Vaara M. Report of four cases of Yersinia pseudotuberculosis septicemia and a literature review. Eur J Clin Microbiol Infect Dis. 1995;14(9):804–10.CrossRef
13.
go back to reference Resseler S, Elewaut A, Verhaegen J, ., Colaert J: Yersinia Pseudotuberculosis, a rare cause of septicemia. Clin Microbiol Newsl 2007, 29(10):76–77.CrossRef Resseler S, Elewaut A, Verhaegen J, ., Colaert J: Yersinia Pseudotuberculosis, a rare cause of septicemia. Clin Microbiol Newsl 2007, 29(10):76–77.CrossRef
14.
go back to reference Lai CH, Lin JN, Chen YH, Chang LL, Huang WY, Ku HP, Lin HH. The first imported human case of Yersinia pseudotuberculosis serotype O1 septicemia presents with acute appendicitis-like syndrome in Taiwan. J Formos Med Assoc. 2014;113(9):656–9.CrossRef Lai CH, Lin JN, Chen YH, Chang LL, Huang WY, Ku HP, Lin HH. The first imported human case of Yersinia pseudotuberculosis serotype O1 septicemia presents with acute appendicitis-like syndrome in Taiwan. J Formos Med Assoc. 2014;113(9):656–9.CrossRef
15.
go back to reference Mashiba K, Kojima T, Ootsuka T, Kusaba T. Yersinia psuedotuberculosis septicemia in a healthy young woman. Kansenshogaku Zasshi. 2008;82(2):86–9.CrossRef Mashiba K, Kojima T, Ootsuka T, Kusaba T. Yersinia psuedotuberculosis septicemia in a healthy young woman. Kansenshogaku Zasshi. 2008;82(2):86–9.CrossRef
16.
go back to reference Ocho K, Iwamuro M, Hasegawa K, Hagiya H, Rai K, Yumoto T, Otsuka F. Far East scarlet-like fever masquerading as adult-onset Kawasaki disease. Intern Med. 2018;57(3):437–40.CrossRef Ocho K, Iwamuro M, Hasegawa K, Hagiya H, Rai K, Yumoto T, Otsuka F. Far East scarlet-like fever masquerading as adult-onset Kawasaki disease. Intern Med. 2018;57(3):437–40.CrossRef
17.
go back to reference Sato K. Clinical findings and epidemiology of Yersinia pseudotuberculosis infection, especially concerned with Izumi fever. Kansenshogaku Zasshi. 1987;61(7):746–62 [Article in Japanese].CrossRef Sato K. Clinical findings and epidemiology of Yersinia pseudotuberculosis infection, especially concerned with Izumi fever. Kansenshogaku Zasshi. 1987;61(7):746–62 [Article in Japanese].CrossRef
18.
go back to reference Kawasaki A, Tsuji K, Doyama H. Multiple small intestine ulcers with desquamation of the fingers. Case Rep Gastroenterol. 2017;11(2):452–61.CrossRef Kawasaki A, Tsuji K, Doyama H. Multiple small intestine ulcers with desquamation of the fingers. Case Rep Gastroenterol. 2017;11(2):452–61.CrossRef
19.
go back to reference American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference: definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Crit Care Med. 1992;20(6):864–7. American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference: definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Crit Care Med. 1992;20(6):864–7.
20.
go back to reference Hoogkamp-Korstanje JA. Antibiotics in Yersinia enterocolitica infections. J Antimicrob Chemother. 1987;20(1):123–31.CrossRef Hoogkamp-Korstanje JA. Antibiotics in Yersinia enterocolitica infections. J Antimicrob Chemother. 1987;20(1):123–31.CrossRef
21.
go back to reference Lemaitre BC, Mazigh DA, Scavizzi MR. Failure of beta-lactam antibiotics and marked efficacy of fluoroquinolones in treatment of murine Yersinia pseudotuberculosis infection. Antimicrob Agents Chemother. 1991;35(9):1785–90.CrossRef Lemaitre BC, Mazigh DA, Scavizzi MR. Failure of beta-lactam antibiotics and marked efficacy of fluoroquinolones in treatment of murine Yersinia pseudotuberculosis infection. Antimicrob Agents Chemother. 1991;35(9):1785–90.CrossRef
Metadata
Title
Septic shock due to Yersinia pseudotuberculosis infection in an adult immunocompetent patient: a case report and literature review
Authors
Takehiro Hashimoto
Ryuichi Takenaka
Haruka Fukuda
Kazuhiko Hashinaga
Shin-ichi Nureki
Hideki Hayashidani
Teruo Sakamoto
Osamu Shigemitsu
Publication date
01-12-2021
Publisher
BioMed Central
Published in
BMC Infectious Diseases / Issue 1/2021
Electronic ISSN: 1471-2334
DOI
https://doi.org/10.1186/s12879-020-05733-w

Other articles of this Issue 1/2021

BMC Infectious Diseases 1/2021 Go to the issue