Skip to main content
Top
Published in: BMC Infectious Diseases 1/2020

Open Access 01-12-2020 | Affective Disorder | Research article

A structural equation model of factors associated with HIV risk behaviors and mental health among men who have sex with men in Malawi

Authors: Yuan Zhao, Amrita Rao, Andrea L. Wirtz, Eric Umar, Gift Trapence, Vincent Jumbe, Sosthenes Ketende, Dunker Kamba, Chris Beyrer, Stefan Baral

Published in: BMC Infectious Diseases | Issue 1/2020

Login to get access

Abstract

Background

Men who have sex with men (MSM) bear a disproportionate burden of HIV in Malawi. Early prevention efforts in Malawi have been largely focused on preventing heterosexual and vertical transmission of HIV, and MSM have rarely been the specific benefactors of these efforts, despite facing both higher prevalence of HIV coupled with multiple barriers to prevention and care. To better facilitate the design of culturally relevant HIV prevention programs and prioritize resources among MSM in resource limited settings, the objective of this analysis was to estimate the relationship between social factors and HIV related risk behaviors and mental health.

Methods

338 MSM were recruited using respondent-driven sampling in Blantyre, Malawi from April 2011 to March 2012. Structural equation models were built to test the association between six latent factors: participation in social activities, social support, stigma and human rights violations, depression symptomatology, condom use, and sexual risk behaviors, including concurrent sexual partnerships and total number of partners.

Results

The mean age of participants was 25 years old. Almost 50% (158/338) of the participants were unemployed and 11% (37/338) were married or cohabiting with women. More than 30% (120/338) of the participants reported sexual behavior stigma and 30% (102/338) reported depression symptomatology. Almost 50% (153/338) of the participants reported any kind of HIV-related risk behaviors and 30% (110/338) participated in one of the recorded social activities. Significant associations were identified between stigma and risk behaviors (β = 0.14, p = 0.03); stigma and depression symptomatology (β = 0.62, p = 0.01); participation in social activities and depression symptomatology (β = 0.17, p = 0.01).

Conclusion

Results suggest MSM reporting stigma are more likely to report sexual risk practices associated with HIV/STI transmission and depressive symptoms, while those reporting participation in social activities related to HIV education are less likely to be depressed. Furthermore, interventions at the community level to support group empowerment and engagement may further reduce risks of HIV transmission and improve mental health outcomes. Taken together, these results suggest the potential additive benefits of mental health services integrated within comprehensive HIV prevention packages to optimize both HIV-related outcomes and general quality of life among MSM in Malawi.
Literature
1.
go back to reference ICF NSO (NSO)[Malawi] and. Malawi Demographic and Health Survey 2015–2016. 2017;. ICF NSO (NSO)[Malawi] and. Malawi Demographic and Health Survey 2015–2016. 2017;.
2.
go back to reference Malawi National Government. Lilongwe: Malawi National Government; 2018. 2018 Global AIDS response progress report. Malawi country report for 2018 and 2019. Malawi National Government. Lilongwe: Malawi National Government; 2018. 2018 Global AIDS response progress report. Malawi country report for 2018 and 2019.
3.
go back to reference Commission NA. Malawi. Malawi AIDS response progress report, 2015 [document on the Internet]. c2015 [cited 2016 Sep 26]. Commission NA. Malawi. Malawi AIDS response progress report, 2015 [document on the Internet]. c2015 [cited 2016 Sep 26].
4.
go back to reference Wirtz AL, Jumbe V, Trapence G, Kamba D, Umar E, Ketende S, et al. HIV among men who have sex with men in Malawi: elucidating HIV prevalence and correlates of infection to inform HIV prevention. J Int AIDS Soc. 2013;16:18742.PubMedPubMedCentralCrossRef Wirtz AL, Jumbe V, Trapence G, Kamba D, Umar E, Ketende S, et al. HIV among men who have sex with men in Malawi: elucidating HIV prevalence and correlates of infection to inform HIV prevention. J Int AIDS Soc. 2013;16:18742.PubMedPubMedCentralCrossRef
5.
go back to reference Wirtz AL, Trapence G, Kamba D, Gama V, Chalera R, Jumbe V, et al. Geographical disparities in HIV prevalence and care among men who have sex with men in Malawi: results from a multisite cross-sectional survey. Lancet HIV. 2017;4(6):e260–9.PubMedCrossRef Wirtz AL, Trapence G, Kamba D, Gama V, Chalera R, Jumbe V, et al. Geographical disparities in HIV prevalence and care among men who have sex with men in Malawi: results from a multisite cross-sectional survey. Lancet HIV. 2017;4(6):e260–9.PubMedCrossRef
6.
go back to reference Poteat T, Ackerman B, Diouf D, Ceesay N, Mothopeng T, Odette K-Z, et al. HIV prevalence and behavioral and psychosocial factors among transgender women and cisgender men who have sex with men in 8 African countries: A cross-sectional analysis. PLoS Med. 2017;14(11):e1002422. Poteat T, Ackerman B, Diouf D, Ceesay N, Mothopeng T, Odette K-Z, et al. HIV prevalence and behavioral and psychosocial factors among transgender women and cisgender men who have sex with men in 8 African countries: A cross-sectional analysis. PLoS Med. 2017;14(11):e1002422.
7.
go back to reference Fay H, Baral SD, Trapence G, Motimedi F, Umar E, Iipinge S, et al. Stigma, health care access, and HIV knowledge among men who have sex with men in Malawi, Namibia, and Botswana. AIDS Behav. 2011;15(6):1088–97.PubMedCrossRef Fay H, Baral SD, Trapence G, Motimedi F, Umar E, Iipinge S, et al. Stigma, health care access, and HIV knowledge among men who have sex with men in Malawi, Namibia, and Botswana. AIDS Behav. 2011;15(6):1088–97.PubMedCrossRef
8.
go back to reference Lick DJ, Durso LE, Johnson KL. Minority stress and physical health among sexual minorities. Perspect Psychol Sci. 2013;8(5):521–48.PubMedCrossRef Lick DJ, Durso LE, Johnson KL. Minority stress and physical health among sexual minorities. Perspect Psychol Sci. 2013;8(5):521–48.PubMedCrossRef
9.
go back to reference Meyer IH. Prejudice, social stress, and mental health in lesbian, gay, and bisexual populations: conceptual issues and research evidence; 2013. Meyer IH. Prejudice, social stress, and mental health in lesbian, gay, and bisexual populations: conceptual issues and research evidence; 2013.
10.
go back to reference Augustinavicius JL, Baral SD, Murray SM, Jackman K, Xue Q-L, Sanchez TH, et al. Characterizing Cross-Culturally Relevant Metrics of Stigma among Men who have Sex with Men across Eight Sub-Saharan African Countries and the United States. Am J Epidemiol [Internet]. 2020:kwz270 Available from: https://pubmed.ncbi.nlm.nih.gov/31942619. Augustinavicius JL, Baral SD, Murray SM, Jackman K, Xue Q-L, Sanchez TH, et al. Characterizing Cross-Culturally Relevant Metrics of Stigma among Men who have Sex with Men across Eight Sub-Saharan African Countries and the United States. Am J Epidemiol [Internet]. 2020:kwz270 Available from: https://​pubmed.​ncbi.​nlm.​nih.​gov/​31942619.
11.
go back to reference Zahn R, Grosso A, Scheibe A, Bekker L-G, Ketende S, Dausab F, et al. Human rights violations among men who have sex with men in Southern Africa: comparisons between legal contexts. PLoS One. 2016;11(1):e0147156. Zahn R, Grosso A, Scheibe A, Bekker L-G, Ketende S, Dausab F, et al. Human rights violations among men who have sex with men in Southern Africa: comparisons between legal contexts. PLoS One. 2016;11(1):e0147156.
12.
go back to reference Mimiaga MJ, Biello KB, Sivasubramanian M, Mayer KH, Anand VR, Safren SA. Psychosocial risk factors for HIV sexual risk among Indian men who have sex with men. AIDS Care. 2013;25(9):1109–13.PubMedPubMedCentralCrossRef Mimiaga MJ, Biello KB, Sivasubramanian M, Mayer KH, Anand VR, Safren SA. Psychosocial risk factors for HIV sexual risk among Indian men who have sex with men. AIDS Care. 2013;25(9):1109–13.PubMedPubMedCentralCrossRef
13.
go back to reference Wirtz A, Trapence G, Jumbe V, Kamba D, Baral S. We are doing these things in an underground way. In: structural barriers to HIV prevention and service utilization among men who have sex with men (MSM) in Malawi (Abstract# TUPE580) XIX International AIDS Conference; 2012. Wirtz A, Trapence G, Jumbe V, Kamba D, Baral S. We are doing these things in an underground way. In: structural barriers to HIV prevention and service utilization among men who have sex with men (MSM) in Malawi (Abstract# TUPE580) XIX International AIDS Conference; 2012.
15.
go back to reference Thomas B, Mimiaga MJ, Menon S, Chandrasekaran V, Murugesan P, Swaminathan S, et al. Unseen and unheard: predictors of sexual risk behavior and HIV infection among men who have sex with men in Chennai, India. AIDS Educ Prev. 2009;21(4):372–83.PubMedPubMedCentralCrossRef Thomas B, Mimiaga MJ, Menon S, Chandrasekaran V, Murugesan P, Swaminathan S, et al. Unseen and unheard: predictors of sexual risk behavior and HIV infection among men who have sex with men in Chennai, India. AIDS Educ Prev. 2009;21(4):372–83.PubMedPubMedCentralCrossRef
16.
go back to reference Skrondal A, Rabe-Hesketh S. Generalized latent variable modeling: multilevel, longitudinal, and structural equation models. USA: Crc Press; 2004. Skrondal A, Rabe-Hesketh S. Generalized latent variable modeling: multilevel, longitudinal, and structural equation models. USA: Crc Press; 2004.
17.
go back to reference Kupek E. Beyond logistic regression: structural equations modelling for binary variables and its application to investigating unobserved confounders. BMC Med Res Methodol. 2006;6(1):13.PubMedPubMedCentralCrossRef Kupek E. Beyond logistic regression: structural equations modelling for binary variables and its application to investigating unobserved confounders. BMC Med Res Methodol. 2006;6(1):13.PubMedPubMedCentralCrossRef
18.
go back to reference Bollen KA, Long JS. Testing structural equation models. Vol. 154. Sage; 1993. Bollen KA, Long JS. Testing structural equation models. Vol. 154. Sage; 1993.
19.
go back to reference Dziak JJ, Coffman DL, Lanza ST, Li R, Jermiin LS. Sensitivity and specificity of information criteria. bioRxiv. 2019;21(2):553-65. Dziak JJ, Coffman DL, Lanza ST, Li R, Jermiin LS. Sensitivity and specificity of information criteria. bioRxiv. 2019;21(2):553-65.
20.
go back to reference Graham SM, Harper GW. Improving HIV prevention and care for African GBMSM. Lancet HIV. 2017;4(6):e234–6.PubMedCrossRef Graham SM, Harper GW. Improving HIV prevention and care for African GBMSM. Lancet HIV. 2017;4(6):e234–6.PubMedCrossRef
21.
go back to reference Musinguzi G, Bastiaens H, Matovu JKB, Nuwaha F, Mujisha G, Kiguli J, et al. Barriers to condom use among high risk men who have sex with men in Uganda: a qualitative study. PLoS One. 2015;10(7):e0132297. Musinguzi G, Bastiaens H, Matovu JKB, Nuwaha F, Mujisha G, Kiguli J, et al. Barriers to condom use among high risk men who have sex with men in Uganda: a qualitative study. PLoS One. 2015;10(7):e0132297.
22.
go back to reference Hergenrather KC, Geishecker S, Clark G, Rhodes SD. A pilot test of the HOPE intervention to explore employment and mental health among African American gay men living with HIV/AIDS: results from a CBPR study. AIDS Educ Prev. 2013;25(5):405–22.PubMedCrossRef Hergenrather KC, Geishecker S, Clark G, Rhodes SD. A pilot test of the HOPE intervention to explore employment and mental health among African American gay men living with HIV/AIDS: results from a CBPR study. AIDS Educ Prev. 2013;25(5):405–22.PubMedCrossRef
23.
go back to reference Grover E, Grosso A, Ketende S, Kennedy C, Fonner V, Adams D, et al. Social cohesion, social participation and HIV testing among men who have sex with men in Swaziland. AIDS Care. 2016;28(6):795–804.PubMedCrossRef Grover E, Grosso A, Ketende S, Kennedy C, Fonner V, Adams D, et al. Social cohesion, social participation and HIV testing among men who have sex with men in Swaziland. AIDS Care. 2016;28(6):795–804.PubMedCrossRef
24.
go back to reference Brown CA, Grosso AL, Adams D, Sithole B, Ketende S, Greene J, et al. Characterizing the individual, social, and structural determinants of condom use among men who have sex with men in Swaziland. AIDS Res Hum Retrovir. 2016;32(6):539–46.PubMedCrossRef Brown CA, Grosso AL, Adams D, Sithole B, Ketende S, Greene J, et al. Characterizing the individual, social, and structural determinants of condom use among men who have sex with men in Swaziland. AIDS Res Hum Retrovir. 2016;32(6):539–46.PubMedCrossRef
25.
go back to reference Pantalone DW, Huh D, Nelson KM, Pearson CR, Simoni JM. Prospective predictors of unprotected anal intercourse among HIV-seropositive men who have sex with men initiating antiretroviral therapy. AIDS Behav. 2014;18(1):78–87.PubMedCrossRef Pantalone DW, Huh D, Nelson KM, Pearson CR, Simoni JM. Prospective predictors of unprotected anal intercourse among HIV-seropositive men who have sex with men initiating antiretroviral therapy. AIDS Behav. 2014;18(1):78–87.PubMedCrossRef
26.
go back to reference Löwe B, Wahl I, Rose M, Spitzer C, Glaesmer H, Wingenfeld K, et al. A 4-item measure of depression and anxiety: validation and standardization of the patient health Questionnaire-4 (PHQ-4) in the general population. J Affect Disord. 2010;122(1–2):86–95.PubMedCrossRef Löwe B, Wahl I, Rose M, Spitzer C, Glaesmer H, Wingenfeld K, et al. A 4-item measure of depression and anxiety: validation and standardization of the patient health Questionnaire-4 (PHQ-4) in the general population. J Affect Disord. 2010;122(1–2):86–95.PubMedCrossRef
27.
go back to reference Kline RB. Principles and practice of structural equation modeling. New York: Guilford publications; 2015. Kline RB. Principles and practice of structural equation modeling. New York: Guilford publications; 2015.
Metadata
Title
A structural equation model of factors associated with HIV risk behaviors and mental health among men who have sex with men in Malawi
Authors
Yuan Zhao
Amrita Rao
Andrea L. Wirtz
Eric Umar
Gift Trapence
Vincent Jumbe
Sosthenes Ketende
Dunker Kamba
Chris Beyrer
Stefan Baral
Publication date
01-12-2020
Publisher
BioMed Central
Published in
BMC Infectious Diseases / Issue 1/2020
Electronic ISSN: 1471-2334
DOI
https://doi.org/10.1186/s12879-020-05310-1

Other articles of this Issue 1/2020

BMC Infectious Diseases 1/2020 Go to the issue