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BMC Gastroenterology

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Open Access 01-12-2020 | Endoscopy | Research article

Increased incidence of metachronous gastric neoplasm after endoscopic resection in patients with synchronous gastric neoplasm

Authors: Ga-Yeong Shin, Hye Jin Cho, Jae Myung Park, Chul-Hyun Lim, Yu Kyung Cho, Myung-Gyu Choi

Published in: BMC Gastroenterology | Issue 1/2020

Abstract

Background

Recurrence risk is a major concern after endoscopic resection (ER) of gastric neoplasms. This study was to compare metachronous risk in patients with and without synchronous neoplasms after complete ER.

Methods

After ER for gastric neoplasms, patients were divided into those with and without synchronous neoplasm. The metachronous risk of gastric neoplasms was compared between the two groups.

Results

After ER of 678 cancers and 891 adenomas, synchronous neoplasm was found in 11.8% of cancers and 11.4% of adenomas. In the multiple (n = 182) and the single group (n = 1387), metachronous neoplasms occurred in 18.1 and 8.6%, respectively (HR 2.40; 95% CI, 1.62–3.34). When the pathology of the recurred lesion was limited to cancer, metachronous risk was also significantly higher in the multiple than in the single group (HR, 2.2; 95% CI, 1.17–3.85). In the recurred pathology of the multiple group, cancer development was frequently observed in patients with cancer compared to those with only adenomas in the synchronous lesion (67.0% vs. 13.0%, respectively; P = 0.023).

Conclusions

This study demonstrated that metachronous risk was significantly higher in patients with synchronous gastric neoplasms after ER. Therefore, meticulous examination is important in patients with synchronous neoplasm.

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Title: Increased incidence of metachronous gastric neoplasm after endoscopic resection in patients with synchronous gastric neoplasm
Authors: Ga-Yeong Shin
Hye Jin Cho
Jae Myung Park
Chul-Hyun Lim
Yu Kyung Cho
Myung-Gyu Choi
Publication date: 01-12-2020
Publisher: BioMed Central
Keywords: Endoscopy
Helicobacter Pylori
Gastric Cancer
Gastric Cancer
Published in: BMC Gastroenterology / Issue 1/2020
Electronic ISSN: 1471-230X
DOI: https://doi.org/10.1186/s12876-020-01358-0

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Increased incidence of metachronous gastric neoplasm after endoscopic resection in patients with synchronous gastric neoplasm

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Conclusions

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