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Published in: BMC Gastroenterology 1/2020

Open Access 01-12-2020 | Nutrition | Research article

Comparison of nutritional screening tools to assess nutritional risk and predict clinical outcomes in Mexican patients with digestive diseases

Authors: Mariana Chávez-Tostado, Gabino Cervantes-Guevara, Sandra Estefanía López-Alvarado, Gabino Cervantes-Pérez, Francisco José Barbosa-Camacho, Clotilde Fuentes-Orozco, Diana Mercedes Hernández-Corona, Tonatiuh González-Heredia, Guillermo Alonso Cervantes-Cardona, Alejandro González-Ojeda

Published in: BMC Gastroenterology | Issue 1/2020

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Abstract

Background

The prevalence of malnutrition remains high in hospitals but no “gold standard” has been established to identify nutritional risks adequately. The Nutrition Risk Screening-2002 (NRS-2002), Subjective Global Assessment (SGA), and Controlling Nutritional Status Index (CONUT) are widely used screening tools, but their efficacy has not yet been compared in Mexican patients. Here, we aimed to compare the efficacy of these tools in identifying nutritional risks within the first 48 h of admission in a group of patients with gastrointestinal diseases.

Methods

This was a cross-sectional study of 196 patients. The results of the screening tools, length of hospital stay, serum albumin and cholesterol concentrations, lymphocyte counts, age, body mass index (BMI), complications, and mortality were analyzed. Kappa (κ) statistics were applied to determine the degree of agreement between tools. The performances of the screening tools in predicting complications and mortality were assessed using binary logistic regression.

Results

The NRS-2002, SGA, and CONUT tools identified nutritional risk in 67, 74, and 51% of the patients, respectively. The observed agreements between tools were: NRS2002/SGA, κ = 0.53; CONUT/NRS-2002, κ = 0.42; and SGA/CONUT, κ = 0.36. Within age groups, the best agreement was found in those aged 51–65 years (κ = 0.68). CONUT and length of stay were both predictive for the number of complications. The number of complications and serum cholesterol concentrations were predictive for mortality.

Conclusions

The proportion of patients identified as having nutritional risk was high using all three screening tools. SGA, NRS-2002, and CONUT had similar capacities for screening risk, but the best agreement was observed between NRS-2002 and SGA. Only CONUT predicted complications, but none of these tools performed well in predicting mortality.
Literature
1.
go back to reference Velasco C, García E, Rodríguez V, Frias L, Garriga R, Álvarez J, et al. Comparison of four nutritional screening tools to detect nutritional risk in hospitalized patients: a multicentre study. Eur J Clin Nutr. 2011;65(2):269–74.CrossRef Velasco C, García E, Rodríguez V, Frias L, Garriga R, Álvarez J, et al. Comparison of four nutritional screening tools to detect nutritional risk in hospitalized patients: a multicentre study. Eur J Clin Nutr. 2011;65(2):269–74.CrossRef
2.
go back to reference Schiesser M, Müller S, Kirchhoff P, Breitenstein S, Schäfer M, Clavien P-A. Assessment of a novel screening score for nutritional risk in predicting complications in gastro-intestinal surgery. Clin Nutr. 2008;27(4):565–70.CrossRef Schiesser M, Müller S, Kirchhoff P, Breitenstein S, Schäfer M, Clavien P-A. Assessment of a novel screening score for nutritional risk in predicting complications in gastro-intestinal surgery. Clin Nutr. 2008;27(4):565–70.CrossRef
3.
go back to reference Liang X, Jiang Z-M, Nolan MT, Wu X, Zhang H, Zheng Y, et al. Nutritional risk, malnutrition (undernutrition), overweight, obesity and nutrition support among hospitalized patients in Beijing teaching hospitals. Asia Pac J Clin Nutr. 2009;18(1):54–62.PubMed Liang X, Jiang Z-M, Nolan MT, Wu X, Zhang H, Zheng Y, et al. Nutritional risk, malnutrition (undernutrition), overweight, obesity and nutrition support among hospitalized patients in Beijing teaching hospitals. Asia Pac J Clin Nutr. 2009;18(1):54–62.PubMed
4.
go back to reference Kyle UG, Kossovsky MP, Karsegard VL, Pichard C. Comparison of tools for nutritional assessment and screening at hospital admission: a population study. Clin Nutr. 2006;25(3):409–17.CrossRef Kyle UG, Kossovsky MP, Karsegard VL, Pichard C. Comparison of tools for nutritional assessment and screening at hospital admission: a population study. Clin Nutr. 2006;25(3):409–17.CrossRef
5.
go back to reference Pérez-Flores JE, Chávez-Tostado M, Larios-del-Toro YE, García-Rentería J, Rendón-Félix J, Salazar-Parra M, et al. Nutritional status assessment at hospital admission and its association with morbidity and mortality in Mexican patients. Nutr Hosp. 2016;33(4):872–8. Pérez-Flores JE, Chávez-Tostado M, Larios-del-Toro YE, García-Rentería J, Rendón-Félix J, Salazar-Parra M, et al. Nutritional status assessment at hospital admission and its association with morbidity and mortality in Mexican patients. Nutr Hosp. 2016;33(4):872–8.
6.
go back to reference Ignacio de Ulíbarri J, González-Madroño A, de Villar NGP, González P, González B, Mancha A, et al. CONUT: a tool for controlling nutritional status. First validation in a hospital population. Nutr Hosp. 2005;20(1):38–45.PubMed Ignacio de Ulíbarri J, González-Madroño A, de Villar NGP, González P, González B, Mancha A, et al. CONUT: a tool for controlling nutritional status. First validation in a hospital population. Nutr Hosp. 2005;20(1):38–45.PubMed
7.
go back to reference Korfalı G, Gündoğdu H, Aydıntuğ S, Bahar M, Besler T, Moral AR, et al. Nutritional risk of hospitalized patients in Turkey. Clin Nutr. 2009;28(5):533–7.CrossRef Korfalı G, Gündoğdu H, Aydıntuğ S, Bahar M, Besler T, Moral AR, et al. Nutritional risk of hospitalized patients in Turkey. Clin Nutr. 2009;28(5):533–7.CrossRef
8.
go back to reference Campos del Portillo R, Palma MiIla S, García Váquez N, Plaza López B, Bermejo López L, Riobó Serván P, et al. Assessment of nutritional status in the healthcare setting in Spain. Nutr Hosp. 2015;31(Suppl 3):196–208.PubMed Campos del Portillo R, Palma MiIla S, García Váquez N, Plaza López B, Bermejo López L, Riobó Serván P, et al. Assessment of nutritional status in the healthcare setting in Spain. Nutr Hosp. 2015;31(Suppl 3):196–208.PubMed
9.
go back to reference García de Lorenzo A, Álvarez Hernández J, Planas M, Burgos R, Araujo K, multidisciplinary consensus work-team on the approach to hospital malnutrition in Spain. Multidisciplinary consensus on the approach to hospital malnutrition in Spain. Nutr Hosp. 2011;26(4):701–10.PubMed García de Lorenzo A, Álvarez Hernández J, Planas M, Burgos R, Araujo K, multidisciplinary consensus work-team on the approach to hospital malnutrition in Spain. Multidisciplinary consensus on the approach to hospital malnutrition in Spain. Nutr Hosp. 2011;26(4):701–10.PubMed
10.
go back to reference Mercadal-Orfila G, Lluch-Taltavull J, Campillo-Artero C, Torrent-Quetglas M. Association between nutritional risk based on the NRS-2002 test and hospital morbidity and mortality. Nutr Hosp. 2012;27(4):1248–54.PubMed Mercadal-Orfila G, Lluch-Taltavull J, Campillo-Artero C, Torrent-Quetglas M. Association between nutritional risk based on the NRS-2002 test and hospital morbidity and mortality. Nutr Hosp. 2012;27(4):1248–54.PubMed
11.
go back to reference Donini LM, Savina C, Rosano A, Cannella C. Systematic review of nutritional status evaluation and screening tools in the elderly. J Nutr Health Aging. 2007;11(5):421–32.PubMed Donini LM, Savina C, Rosano A, Cannella C. Systematic review of nutritional status evaluation and screening tools in the elderly. J Nutr Health Aging. 2007;11(5):421–32.PubMed
12.
go back to reference Foley NC, Salter KL, Robertson J, Teasell RW, Woodbury MG. Which reported estimate of the prevalence of malnutrition after stroke is valid? Stroke. 2009;40:e66–74 [cited 2020 Feb 16].CrossRef Foley NC, Salter KL, Robertson J, Teasell RW, Woodbury MG. Which reported estimate of the prevalence of malnutrition after stroke is valid? Stroke. 2009;40:e66–74 [cited 2020 Feb 16].CrossRef
13.
go back to reference Wang F, Chen W, Bruening KS, Raj S, Larsen DA. Nutrition screening tools and the prediction of clinical outcomes among chinese hospitalized gastrointestinal disease patients. PLoS One. 2016;11(8):e0159436 Green J, editor.CrossRef Wang F, Chen W, Bruening KS, Raj S, Larsen DA. Nutrition screening tools and the prediction of clinical outcomes among chinese hospitalized gastrointestinal disease patients. PLoS One. 2016;11(8):e0159436 Green J, editor.CrossRef
14.
go back to reference van Bokhorst-de van der Schueren MAE, Guaitoli PR, Jansma EP, de Vet HCW. Nutrition screening tools: does one size fit all? A systematic review of screening tools for the hospital setting. Clin Nutr. 2014;33(1):39–58.CrossRef van Bokhorst-de van der Schueren MAE, Guaitoli PR, Jansma EP, de Vet HCW. Nutrition screening tools: does one size fit all? A systematic review of screening tools for the hospital setting. Clin Nutr. 2014;33(1):39–58.CrossRef
15.
go back to reference Kos M, Titiz H, Onec B, Soysal T, Kutlucan A, Sahiner Emen S, et al. Association of “controlling nutritional status index” and “prognostic nutritional index” with intensive care unit survival in elderly patients. Eur Geriatr Med. 2016;7(1):13–7.CrossRef Kos M, Titiz H, Onec B, Soysal T, Kutlucan A, Sahiner Emen S, et al. Association of “controlling nutritional status index” and “prognostic nutritional index” with intensive care unit survival in elderly patients. Eur Geriatr Med. 2016;7(1):13–7.CrossRef
16.
go back to reference Sun X, Luo L, Zhao X, Ye P. Controlling nutritional status (CONUT) score as a predictor of all-cause mortality in elderly hypertensive patients: a prospective follow-up study. BMJ Open. 2017;7(9):e015649.CrossRef Sun X, Luo L, Zhao X, Ye P. Controlling nutritional status (CONUT) score as a predictor of all-cause mortality in elderly hypertensive patients: a prospective follow-up study. BMJ Open. 2017;7(9):e015649.CrossRef
17.
go back to reference Detsky A, McLaughlin, Baker J, Johnston N, Whittaker S, Mendelson R, et al. What is subjective global assessment of nutritional status? J Parenter Enter Nutr. 1987;11(1):8–13.CrossRef Detsky A, McLaughlin, Baker J, Johnston N, Whittaker S, Mendelson R, et al. What is subjective global assessment of nutritional status? J Parenter Enter Nutr. 1987;11(1):8–13.CrossRef
18.
go back to reference Filipović BF, Gajić M, Milinić N, Milovanović B, Filipović BR, Cvetković M, et al. Comparison of two nutritional assessment methods in gastroenterology patients. World J Gastroenterol. 2010;16(16):1999–2004.CrossRef Filipović BF, Gajić M, Milinić N, Milovanović B, Filipović BR, Cvetković M, et al. Comparison of two nutritional assessment methods in gastroenterology patients. World J Gastroenterol. 2010;16(16):1999–2004.CrossRef
19.
go back to reference Leandro-Merhi VA, Braga de Aquino JL. Comparison of nutritional diagnosis methods and prediction of clinical outcomes in patients with neoplasms and digestive tract diseases. Clin Nutr. 2015;34(4):647–51.CrossRef Leandro-Merhi VA, Braga de Aquino JL. Comparison of nutritional diagnosis methods and prediction of clinical outcomes in patients with neoplasms and digestive tract diseases. Clin Nutr. 2015;34(4):647–51.CrossRef
20.
go back to reference Reber E, Gomes F, Vasiloglou MF, Schuetz P, Stanga Z. Nutritional risk screening and assessment. J Clin Med. 2019;8(7):1065.CrossRef Reber E, Gomes F, Vasiloglou MF, Schuetz P, Stanga Z. Nutritional risk screening and assessment. J Clin Med. 2019;8(7):1065.CrossRef
21.
go back to reference Kondrup J, Rasmussen HH, Hamberg O, Stanga Z. Ad hoc ESPEN working group. Nutritional risk screening (NRS 2002): a new method based on an analysis of controlled clinical trials. Clin Nutr. 2003;22(3):321–36.CrossRef Kondrup J, Rasmussen HH, Hamberg O, Stanga Z. Ad hoc ESPEN working group. Nutritional risk screening (NRS 2002): a new method based on an analysis of controlled clinical trials. Clin Nutr. 2003;22(3):321–36.CrossRef
22.
go back to reference Kondrup J, Allison SP, Elia M, Vellas B, Plauth M. Educational and clinical practice committee, European Society of Parenteral and Enteral Nutrition (ESPEN). ESPEN guidelines for nutrition screening 2002. Clin Nutr. 2003;22(4):415–21.CrossRef Kondrup J, Allison SP, Elia M, Vellas B, Plauth M. Educational and clinical practice committee, European Society of Parenteral and Enteral Nutrition (ESPEN). ESPEN guidelines for nutrition screening 2002. Clin Nutr. 2003;22(4):415–21.CrossRef
23.
go back to reference Schuetz P, Fehr R, Baechli V, Geiser M, Deiss M, Gomes F, et al. Individualised nutritional support in medical inpatients at nutritional risk: a randomised clinical trial. Lancet. 2019;393(10188):2312–21.CrossRef Schuetz P, Fehr R, Baechli V, Geiser M, Deiss M, Gomes F, et al. Individualised nutritional support in medical inpatients at nutritional risk: a randomised clinical trial. Lancet. 2019;393(10188):2312–21.CrossRef
24.
go back to reference Gibbs J, Cull W, Henderson W, Daley J, Hur K, Khuri SF. Preoperative serum albumin level as a predictor of operative mortality and morbidity: results from the national VA surgical risk study. Arch Surg. 1999;134(1):36–42.CrossRef Gibbs J, Cull W, Henderson W, Daley J, Hur K, Khuri SF. Preoperative serum albumin level as a predictor of operative mortality and morbidity: results from the national VA surgical risk study. Arch Surg. 1999;134(1):36–42.CrossRef
25.
go back to reference Liu Y, Coresh J, Eustace JA, Longenecker JC, Jaar B, Fink NE, et al. Association between cholesterol level and mortality in Dialysis patients: role of inflammation and malnutrition. J Am Med Assoc. 2004;291(4):451–9.CrossRef Liu Y, Coresh J, Eustace JA, Longenecker JC, Jaar B, Fink NE, et al. Association between cholesterol level and mortality in Dialysis patients: role of inflammation and malnutrition. J Am Med Assoc. 2004;291(4):451–9.CrossRef
26.
go back to reference Jellinge ME, Henriksen DP, Hallas P, Brabrand M. Hypoalbuminemia is a strong predictor of 30-day all-cause mortality in acutely admitted medical patients: a prospective, observational, cohort study. PLoS One. 2014;9(8):e105983.CrossRef Jellinge ME, Henriksen DP, Hallas P, Brabrand M. Hypoalbuminemia is a strong predictor of 30-day all-cause mortality in acutely admitted medical patients: a prospective, observational, cohort study. PLoS One. 2014;9(8):e105983.CrossRef
27.
go back to reference Amaral TF, Matos LC, Teixeira MA, Tavares MM, Álvares L, Antunes A. Undernutrition and associated factors among hospitalized patients. Clin Nutr. 2010;29(5):580–5.CrossRef Amaral TF, Matos LC, Teixeira MA, Tavares MM, Álvares L, Antunes A. Undernutrition and associated factors among hospitalized patients. Clin Nutr. 2010;29(5):580–5.CrossRef
28.
go back to reference Allard JP, Keller H, Jeejeebhoy KN, Laporte M, Duerksen DR, Gramlich L, et al. Malnutrition at hospital admission - contributors and effect on length of stay: a prospective cohort study from the Canadian malnutrition task force. J Parenter Enter Nutr. 2014;40(4):487–97.CrossRef Allard JP, Keller H, Jeejeebhoy KN, Laporte M, Duerksen DR, Gramlich L, et al. Malnutrition at hospital admission - contributors and effect on length of stay: a prospective cohort study from the Canadian malnutrition task force. J Parenter Enter Nutr. 2014;40(4):487–97.CrossRef
29.
go back to reference Alpízar J, Torres Z, Guadalupe M, García M, Barretero R, Yolanda D, et al. Prevalence of nutritional risk in a hospital of second level in the Mexico state. Nutr Clín Diet Hosp. 2016;36(4):111–6. Alpízar J, Torres Z, Guadalupe M, García M, Barretero R, Yolanda D, et al. Prevalence of nutritional risk in a hospital of second level in the Mexico state. Nutr Clín Diet Hosp. 2016;36(4):111–6.
30.
go back to reference Shrout PE. Measurement reliability and agreement in psychiatry. Stat Methods Med Res. 1998;7(3):301–17.CrossRef Shrout PE. Measurement reliability and agreement in psychiatry. Stat Methods Med Res. 1998;7(3):301–17.CrossRef
31.
go back to reference Liang X, Jiang ZM, Nolan MT, Efron DT, Kondrup J. Comparative survey on nutritional risk and nutritional support between Beijing and Baltimore teaching hospitals. Nutrition. 2008;24(10):969–76.CrossRef Liang X, Jiang ZM, Nolan MT, Efron DT, Kondrup J. Comparative survey on nutritional risk and nutritional support between Beijing and Baltimore teaching hospitals. Nutrition. 2008;24(10):969–76.CrossRef
32.
go back to reference Raslan M, Gonzalez MC, Gonçalves Dias MC, Nascimento M, Castro M, Marques P, et al. Comparison of nutritional risk screening tools for predicting clinical outcomes in hospitalized patients. Nutrition. 2010;26(7–8):721–6.CrossRef Raslan M, Gonzalez MC, Gonçalves Dias MC, Nascimento M, Castro M, Marques P, et al. Comparison of nutritional risk screening tools for predicting clinical outcomes in hospitalized patients. Nutrition. 2010;26(7–8):721–6.CrossRef
33.
go back to reference Rasmussen H, Kondrup J, Staun M, Ladefoged K, Kristensen H, Wengler A. Prevalence of patients at nutritional risk in Danish hospitals. Clin Nutr. 2004;23(5):1009–15.CrossRef Rasmussen H, Kondrup J, Staun M, Ladefoged K, Kristensen H, Wengler A. Prevalence of patients at nutritional risk in Danish hospitals. Clin Nutr. 2004;23(5):1009–15.CrossRef
34.
go back to reference Takaoka A, Sasaki M, Nakanishi N, Kurihara M, Ohi A, Bamba S, et al. Nutritional screening and clinical outcome in hospitalized patients with Crohn’s disease. Ann Nutr Metab. 2018;71(3–4):266–72. Takaoka A, Sasaki M, Nakanishi N, Kurihara M, Ohi A, Bamba S, et al. Nutritional screening and clinical outcome in hospitalized patients with Crohn’s disease. Ann Nutr Metab. 2018;71(3–4):266–72.
35.
go back to reference Jeejeebhoy KN, Duerksen DR. Malnutrition in gastrointestinal disorders: detection and nutritional assessment. Gastroenterol Clin N Am. 2018;47:1–22 W.B. Saunders.CrossRef Jeejeebhoy KN, Duerksen DR. Malnutrition in gastrointestinal disorders: detection and nutritional assessment. Gastroenterol Clin N Am. 2018;47:1–22 W.B. Saunders.CrossRef
36.
go back to reference Marshall J, Lopez T, Shetterly S, Morgenstern N, Baer K, Swenson C, et al. Indicators of nutritional risk in a rural elderly Hispanic and non-Hispanic white population. J Am Diet Assoc. 1999;99(3):315–22.CrossRef Marshall J, Lopez T, Shetterly S, Morgenstern N, Baer K, Swenson C, et al. Indicators of nutritional risk in a rural elderly Hispanic and non-Hispanic white population. J Am Diet Assoc. 1999;99(3):315–22.CrossRef
37.
go back to reference Kyle UG, Genton L, Pichard C. Hospital length of stay and nutritional status. Curr Opin Clin Nutr Metab Care. 2005;8(4):397–402.CrossRef Kyle UG, Genton L, Pichard C. Hospital length of stay and nutritional status. Curr Opin Clin Nutr Metab Care. 2005;8(4):397–402.CrossRef
38.
go back to reference Vyroubal P, Chiarla C, Giovannini I, Hyspler R, Ticha A, Hrnciarikova D, et al. Hypocholesterolemia in clinically serious conditions--review. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2008;152:181–9.CrossRef Vyroubal P, Chiarla C, Giovannini I, Hyspler R, Ticha A, Hrnciarikova D, et al. Hypocholesterolemia in clinically serious conditions--review. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2008;152:181–9.CrossRef
Metadata
Title
Comparison of nutritional screening tools to assess nutritional risk and predict clinical outcomes in Mexican patients with digestive diseases
Authors
Mariana Chávez-Tostado
Gabino Cervantes-Guevara
Sandra Estefanía López-Alvarado
Gabino Cervantes-Pérez
Francisco José Barbosa-Camacho
Clotilde Fuentes-Orozco
Diana Mercedes Hernández-Corona
Tonatiuh González-Heredia
Guillermo Alonso Cervantes-Cardona
Alejandro González-Ojeda
Publication date
01-12-2020
Publisher
BioMed Central
Keyword
Nutrition
Published in
BMC Gastroenterology / Issue 1/2020
Electronic ISSN: 1471-230X
DOI
https://doi.org/10.1186/s12876-020-01214-1

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