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BMC Gastroenterology
Published in: BMC Gastroenterology 1/2018

Open Access 01-12-2018 | Research article

Biologic treatment of Japanese patients with inflammatory bowel disease

Authors: Jörg Mahlich, Katsuyoshi Matsuoka, Rosarin Sruamsiri

Published in: BMC Gastroenterology | Issue 1/2018

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Abstract

Background

There is little information regarding the use of biologics in Inflammatory Bowel Disease (IBD) patients in Japan. The aim of this study was to determine the factors associated with the use of biologics in the treatment of Japanese patients with IBD.

Methods

An online survey was conducted among Japanese patients with IBD (n = 1035). Socioeconomic as well as treatment related information was collected. Logistic regression was applied to analyze the determinants of biologic treatment.

Results

Younger age (≤ 40 years vs. > 65 years; OR:0.24), time since diagnosis (< 2 years vs. < 15 years; OR: 4.16), surgical history (OR:1.98) and visiting university hospitals (university hospitals vs. clinics; OR: 0.47) were associated with biologic treatment for Japanese IBD patients.

Conclusions

Currently, biologics have been used in younger IBD patients which may give rise to the presence of an age bias in biologic treatment. Further studies are required to confirm these results and to define appropriate IBD patients who should be treated with biologic agent.
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Metadata
Title
Biologic treatment of Japanese patients with inflammatory bowel disease
Authors
Jörg Mahlich
Katsuyoshi Matsuoka
Rosarin Sruamsiri
Publication date
01-12-2018
Publisher
BioMed Central
Published in
BMC Gastroenterology / Issue 1/2018
Electronic ISSN: 1471-230X
DOI
https://doi.org/10.1186/s12876-018-0892-x

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