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Published in: BMC Cardiovascular Disorders 1/2021

01-12-2021 | Angiography | Research article

Echocardiographic and laboratory findings in coronary slow flow phenomenon: cross-sectional study and review

Authors: Mir Hosein Seyyed Mohammadzad, Kamal Khademvatani, Salar Gardeshkhah, Amin Sedokani

Published in: BMC Cardiovascular Disorders | Issue 1/2021

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Abstract

Background

Coronary sow-flow phenomenon (CSFP) is defined as slow passage of the contrast injected into the coronary arteries without distal obstruction of the vessel.

Methods

The present study was a cross-sectional, descriptive-analytical study performed at the Seyed-al-Shohada Heart Center during 2018–2019. The eligible patients based on the inclusion and exclusion criteria were divided into the study group showing the CSFP and the control group with normal epicardial coronary arteries.

Results

The study included 124 patients. 67.9% of the study group and 39.4% of the control group were male patients (p-value = 0.001), and the mean patient age was 52.18 ± 12.55 and 51.77 ± 10.36 years in the study and control groups, respectively (p-value = 0.18). The study group had a significantly higher BMI than the control group (p < 0.05) and also a higher prevalence of smoking and hypertension. The variables of ALC, Hct, Plt, MPV, RDW, Cr, triglyceride, TC, and LDL, were higher in the study group. Given the echocardiographic findings, the mean E wave was significantly lower in the study group, while the control group had a significantly higher GLS (p-value = 0.01). Also, left anterior descending artery was the most common artery involved with CSFP.

Conclusion

The CSFP was significantly more common in men, smokers, hypertensive patients, and patients with high BMI. Moreover, these patients had significantly higher platelet count, MPV, LDL, and FBS. Some other laboratory variables were also higher in these patients. Given the echocardiographic findings, mild diastolic dysfunction and low GLS were also observed in the study group.
Literature
7.
go back to reference Kaski JC, Eslick GD, Merz CNB. Chest pain with normal coronary arteries: a multidisciplinary approach. Berlin: Springer; 2013.CrossRef Kaski JC, Eslick GD, Merz CNB. Chest pain with normal coronary arteries: a multidisciplinary approach. Berlin: Springer; 2013.CrossRef
14.
go back to reference Kaneko A, Tanaka H, Onishi T, et al. Subendocardial dysfunction in patients with chronic severe aortic regurgitation and preserved ejection fraction detected with speckle-tracking strain imaging and transmural myocardial strain profile. Eur Heart J Cardiovasc Imaging. 2013;14(4):339–46. https://doi.org/10.1093/ehjci/jes160.CrossRefPubMed Kaneko A, Tanaka H, Onishi T, et al. Subendocardial dysfunction in patients with chronic severe aortic regurgitation and preserved ejection fraction detected with speckle-tracking strain imaging and transmural myocardial strain profile. Eur Heart J Cardiovasc Imaging. 2013;14(4):339–46. https://​doi.​org/​10.​1093/​ehjci/​jes160.CrossRefPubMed
27.
go back to reference Pontiroli AE, Pizzocri P, Paroni R, Folli F. Sympathetic overactivity, endothelial dysfunction, inflammation, and metabolic abnormalities cluster in grade III (World Health Organization) obesity: reversal through sustained weight loss obtained with laparoscopic adjustable gastric banding. Diabetes Care. 2006;29(12):2735–8. https://doi.org/10.2337/dc06-1417.CrossRefPubMed Pontiroli AE, Pizzocri P, Paroni R, Folli F. Sympathetic overactivity, endothelial dysfunction, inflammation, and metabolic abnormalities cluster in grade III (World Health Organization) obesity: reversal through sustained weight loss obtained with laparoscopic adjustable gastric banding. Diabetes Care. 2006;29(12):2735–8. https://​doi.​org/​10.​2337/​dc06-1417.CrossRefPubMed
34.
go back to reference Altun I, Akin F, Kose N, Sahin C, Kirli I. Predictors of slow flow in angiographically normal coronary arteries. Int J Clin Exp Med. 2015;8(8):13762–8.PubMedPubMedCentral Altun I, Akin F, Kose N, Sahin C, Kirli I. Predictors of slow flow in angiographically normal coronary arteries. Int J Clin Exp Med. 2015;8(8):13762–8.PubMedPubMedCentral
37.
go back to reference Moazenzadeh M, Azimzadeh BS, Zare J, Shokouhi M, Sheikhvatan M. Clinical features and main determinants of coronary slow flow phenomenon in Iranian patients. Eur J Cardiovasc Med. 2010;1(2):2042. Moazenzadeh M, Azimzadeh BS, Zare J, Shokouhi M, Sheikhvatan M. Clinical features and main determinants of coronary slow flow phenomenon in Iranian patients. Eur J Cardiovasc Med. 2010;1(2):2042.
43.
go back to reference Lanza G, Andreotti F, Sestito A, Sciahbasi A, Crea F, Maseri A. Platelet aggregability in cardiac syndrome X. Eur Heart J. 2001;22(20):1924–30.CrossRefPubMed Lanza G, Andreotti F, Sestito A, Sciahbasi A, Crea F, Maseri A. Platelet aggregability in cardiac syndrome X. Eur Heart J. 2001;22(20):1924–30.CrossRefPubMed
Metadata
Title
Echocardiographic and laboratory findings in coronary slow flow phenomenon: cross-sectional study and review
Authors
Mir Hosein Seyyed Mohammadzad
Kamal Khademvatani
Salar Gardeshkhah
Amin Sedokani
Publication date
01-12-2021
Publisher
BioMed Central
Published in
BMC Cardiovascular Disorders / Issue 1/2021
Electronic ISSN: 1471-2261
DOI
https://doi.org/10.1186/s12872-021-02044-z

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