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BMC Cardiovascular Disorders
Published in: BMC Cardiovascular Disorders 1/2016

Open Access 01-12-2016 | Research article

Association of affective temperaments with blood pressure and arterial stiffness in hypertensive patients: a cross-sectional study

Authors: Andrea László, Ádám Tabák, Beáta Kőrösi, Dániel Eörsi, Péter Torzsa, Orsolya Cseprekál, András Tislér, György Reusz, Zsófia Nemcsik-Bencze, Xénia Gonda, Zoltán Rihmer, János Nemcsik

Published in: BMC Cardiovascular Disorders | Issue 1/2016

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Abstract

Background

Affective temperaments (anxious, depressive, cyclothymic, irritable and hyperthymic) measure subclinical manifestations of major mood disorders. Furthermore, cumulating evidence suggests their involvement in somatic disorders as well. We aimed to assess associations between affective temperament scores and blood pressure and arterial stiffness parameters in hypertensive patients.

Methods

In this cross-sectional study, 173 patients with well-controlled or grade 1 chronic hypertension, with no history of depression, completed the TEMPS-A, Beck Depression Inventory (BDI) and Hamilton Anxiety Scale (HAM-A) questionnaires in three GP practices. Arterial stiffness was measured with tonometry (PulsePen).

Results

According to multiple linear regression analysis, cyclothymic temperament score was positively associated with brachial systolic blood pressure independently of age, sex, total cholesterol, brachial diastolic blood pressure, BDI, HAM-A and the use of alprazolam (β = 0.529, p = 0.042), while hyperthymic temperament score was negatively related to augmentation index independent of age, sex, smoking, heart rate, BDI, HAM-A and the use of alprazolam (β = -0.612, p = 0.013). A significant interaction was found between cyclothymic temperament score and sex in predicting brachial systolic blood pressure (p = 0.025), between irritable and anxious temperament scores and sex in predicting pulse wave velocity (p = 0.021, p = 0.023, respectively) and an interaction with borderline significance between hyperthymic temperament score and sex in predicting augmentation index (p = 0.052).

Conclusions

The present findings highlight elevated blood pressure among subjects with high cyclothymic temperament as well as an increased level of arterial stiffening in subjects with low hyperthymic scores suggesting that affective temperaments may play a role in the development of hypertension and arterial stiffening and may thus represent markers of cardiovascular risk. Sex differences were also present in these associations.
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Metadata
Title
Association of affective temperaments with blood pressure and arterial stiffness in hypertensive patients: a cross-sectional study
Authors
Andrea László
Ádám Tabák
Beáta Kőrösi
Dániel Eörsi
Péter Torzsa
Orsolya Cseprekál
András Tislér
György Reusz
Zsófia Nemcsik-Bencze
Xénia Gonda
Zoltán Rihmer
János Nemcsik
Publication date
01-12-2016
Publisher
BioMed Central
Published in
BMC Cardiovascular Disorders / Issue 1/2016
Electronic ISSN: 1471-2261
DOI
https://doi.org/10.1186/s12872-016-0337-9

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