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Open Access 01-12-2015 | Review

Subversion of the B-cell compartment during parasitic, bacterial, and viral infections

Authors: Gwenoline Borhis, Yolande Richard

Published in: BMC Immunology | Issue 1/2015

Abstract

Recent studies on HIV infection have identified new human B-cell subsets with a potentially important impact on anti-viral immunity. Current work highlights the occurrence of similar B-cell alterations in other viral, bacterial, and parasitic infections, suggesting that common strategies have been developed by pathogens to counteract protective immunity. For this review, we have selected key examples of human infections for which B-cell alterations have been described, to highlight the similarities and differences in the immune responses to a variety of pathogens. We believe that further comparisons between these models will lead to critical progress in the understanding of B-cell mechanisms and will open new target avenues for therapeutic interventions.

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Title: Subversion of the B-cell compartment during parasitic, bacterial, and viral infections
Authors: Gwenoline Borhis
Yolande Richard
Publication date: 01-12-2015
Publisher: BioMed Central
Published in: BMC Immunology / Issue 1/2015
Electronic ISSN: 1471-2172
DOI: https://doi.org/10.1186/s12865-015-0079-y

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Sequence conservation analysis and in silico human leukocyte antigen-peptide binding predictions for the Mtb72F and M72 tuberculosis candidate vaccine antigens

Involvement of soluble scavenger receptor A in suppression of T cell activation in patients with chronic hepatitis B

All-trans retinoid acid promotes allogeneic corneal graft survival in mice by regulating Treg-Th17 balance in the presence of TGF-β

Immunosenescence of the CD8+ T cell compartment is associated with HIV-infection, but only weakly reflects age-related processes of adipose tissue, metabolism, and muscle in antiretroviral therapy-treated HIV-infected patients and controls

Immunogenicity of infectious pathogens and vaccine antigens

ACC 2024 Congress Coverage

Year in Review: Heart failure and cardiomyopathies

Semaglutide benefits people with type 2 diabetes and obesity-related heart failure

Incentivised to exercise

New intervention for STEMI-related cardiogenic shock

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