Published in:
Open Access
01-12-2012 | Poster presentation
Abnormal expressions of immune response-related genes in RA bone marrow cells
Authors:
Hooi-Ming Lee, Chieko Aoki, Yasunori Shimaoka, Kensuke Ochi, Takahiro Ochi, Norihiro Nishimoto
Published in:
Arthritis Research & Therapy
|
Special Issue 1/2012
Login to get access
Excerpt
Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by chronic synovitis that progresses to destruction of cartilage and bone. Bone marrow (BM) cells have been shown to contribute to this pathogenesis. In this study, we compared differentially expressed molecules in BM cells from RA and osteoarthritis (OA) patients and analyzed abnormal regulatory networks to identify the role of BM cells in RA. …