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Arthritis Research & Therapy
Published in: Arthritis Research & Therapy 1/2012

Open Access 01-12-2012 | Oral presentation

From rheumatic diseases to cancer - role of autoantibodies as diagnostic biomarkers

Author: Eng M Tan

Published in: Arthritis Research & Therapy | Special Issue 1/2012

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Excerpt

Rheumatology has pioneered in the study of autoantibodies by showing that they are not only involved in pathogenesis but are also highly useful as diagnostic biomarkers. The diagnostic biomarker aspect of autoimmunity has gained increasing importance in cancer and many of the insights gained in Rheumatology have contributed to understanding the significance of autoantibodies in cancer. …
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Tan EM, Zhang J: Autoantibodies to tumor-associated antigens: reporters from the immune system. Immunol Rev. 2008, 222: 328-340. 10.1111/j.1600-065X.2008.00611.x.PubMedCentralCrossRefPubMed
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Robles AI, Harris CC: Clinical outcomes and correlates of TP53 mutations and cancer. Cold Spring Harb Perspect Biol. 2010, 2 (3): a001016-10.1101/cshperspect.a001016. ReviewPubMedCentralCrossRefPubMed
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Efeyan A, Serrano M: p53: guardian of the genome and policeman of the oncogenes. Cell Cycle. 2007, 6: 1006-1010. 10.4161/cc.6.9.4211.CrossRefPubMed
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SooHoo L, Chan EK: Cloning and characterization of a novel 90 kDa 'companion' autoantigen of p62 overexpressed in cancer. Oncogene. 2002, 21: 5006-5015. 10.1038/sj.onc.1205625.CrossRef
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Metadata
Title
From rheumatic diseases to cancer - role of autoantibodies as diagnostic biomarkers
Author
Eng M Tan
Publication date
01-12-2012
Publisher
BioMed Central
Published in
Arthritis Research & Therapy / Issue Special Issue 1/2012
Electronic ISSN: 1478-6362
DOI
https://doi.org/10.1186/ar3557

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At a glance: The STEP trials

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Developed by: Springer Medicine

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