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Arthritis Research & Therapy
Published in: Arthritis Research & Therapy 1/2012

Open Access 01-12-2012 | Oral presentation

Future direction of pathogenesis and treatment for rheumatic disorders

Author: Steffen Gay

Published in: Arthritis Research & Therapy | Special Issue 1/2012

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Excerpt

After the breakthrough in the treatment of rheumatoid arthritis and numerous related disorders with biological therapies targeting TNFa at the Kennedy Institute in London …
Literature
1.
2.
Karouzakis E, et al: Epigenetic control in rheumatoid arthritis synovial fibroblasts. Nat Rev Rheumatol. 2009, 5: 266-72. 10.1038/nrrheum.2009.55.CrossRefPubMed
3.
Brock M, et al: Interleukin-6 modulates the expression of the bone morphogenic protein receptor type II through a novel STAT3-microRNA cluster 17/92 pathway. Circ Res. 2009, 104: 1184-91. 10.1161/CIRCRESAHA.109.197491.CrossRefPubMed
4.
Stanczyk J, et al: Altered expression of miRNA-203 in rheumatoid arthritis synovial fibroblasts and its role in fibroblast activation. Arthritis Rheum. 2011, 63: 373-81. 10.1002/art.30115.PubMedCentralCrossRefPubMed
5.
Metadata
Title
Future direction of pathogenesis and treatment for rheumatic disorders
Author
Steffen Gay
Publication date
01-12-2012
Publisher
BioMed Central
Published in
Arthritis Research & Therapy / Issue Special Issue 1/2012
Electronic ISSN: 1478-6362
DOI
https://doi.org/10.1186/ar3556

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At a glance: The STEP trials

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Developed by: Springer Medicine

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