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Arthritis Research & Therapy
Published in: Arthritis Research & Therapy 1/2004

01-02-2004 | Meeting abstract

The presence of deiminated fibrin in the synovial membrane is not specific for rheumatoid arthritis

Authors: S Chapuy-Regaud, M Sebbag, D Baeten, C Clavel, F De Keyser, G Serre

Published in: Arthritis Research & Therapy | Special Issue 1/2004

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Excerpt

Autoantibodies to deiminated (citrullinated) forms of the α and β chains of fibrin (AhFibA), also known as antifilaggrin autoantibodies (AFA), are the most specific serological markers of rheumatoid arthritis (RA). Deimination is critical in generating the AhFibA epitopes and, in the synovial tissue (ST), deiminated fibrin is their major antigenic target. Existence of fibrin deimination specifically in RA patients could explain why the AhFibA response is RA specific. …
Metadata
Title
The presence of deiminated fibrin in the synovial membrane is not specific for rheumatoid arthritis
Authors
S Chapuy-Regaud
M Sebbag
D Baeten
C Clavel
F De Keyser
G Serre
Publication date
01-02-2004
Publisher
BioMed Central
Published in
Arthritis Research & Therapy / Issue Special Issue 1/2004
Electronic ISSN: 1478-6362
DOI
https://doi.org/10.1186/ar1062

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Keynote webinar | Spotlight on medication adherence

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Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

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Developed by: Springer Medicine
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