Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress 2023 EHA Congress 2023 ASCO Annual Meeting
Clinical Collections
Advances in Alzheimer’s

Keynote webinar | Spotlight on sleep in brain health

LIVE: Thursday 2nd May 2024, 18:00-19:30 (CEST)

Quality sleep is essential for health. But what happens to our brains when sleep patterns are disturbed? Join our experts to explore the interplay between sleep disruption and neurological diseases, and the questions that you need to be asking your patients to help you prevent the harmful effects of sleep deprivation.
ADVANCED SEARCH
Log in
Top
Medical Gas Research
Published in: Medical Gas Research 1/2013

Open Access 01-12-2013 | Review

Cold Atmospheric Plasma: methods of production and application in dentistry and oncology

Authors: Clotilde Hoffmann, Carlos Berganza, John Zhang

Published in: Medical Gas Research | Issue 1/2013

Login to get access

Abstract

Cold Atmospheric Plasma is an ionized gas that has recently been extensively studied by researchers as a possible therapy in dentistry and oncology. Several different gases can be used to produce Cold Atmospheric Plasma such as Helium, Argon, Nitrogen, Heliox, and air. There are many methods of production by which cold atmospheric plasma is created. Each unique method can be used in different biomedical areas. In dentistry, researchers have mostly investigated the antimicrobial effects produced by plasma as a means to remove dental biofilms and eradicate oral pathogens. It has been shown that reactive oxidative species, charged particles, and UV photons play the main role. Cold Atmospheric Plasma has also found a minor, but important role in tooth whitening and composite restoration. Furthermore, it has been demonstrated that Cold Atmospheric Plasma induces apoptosis, necrosis, cell detachment, and senescence by disrupting the S phase of cell replication in tumor cells. This unique finding opens up its potential therapy in oncology.
Appendix
Available only for authorised users
Literature
1.
García-Alcantara E, López-Callejas R, Morales-Ramírez PR, Peña-Eguiluz R, Fajardo-Muñoz R, Mercado-Cabrera A, Barocio SR, Valencia-Alvarado R, Rodríguez-Méndez BG, Muñoz-Castro AE, de la Piedad-Beneitez A, Rojas-Olmedo IA: Accelerated mice skin acute wound healing in vivo by combined treatment of argon and helium plasma needle. Arch Med Res. 2013, 44 (3): 169-177. 10.1016/j.arcmed.2013.02.001.PubMedCrossRef
2.
Ziuzina D, Patil S, Cullen PJ, Keener KM, Bourke P: Atmospheric cold plasma inactivation of Escherichia coli in liquid media inside a sealed package. J Appl Microbiol. 2012, 114 (3): 778-787.CrossRef
3.
Arjunan KP, Clyne AM: Hydroxyl radical and hydrogen peroxide are primarily responsible for dielectric barrier discharge plasma induced angiogenesis. Plasma Process Polym. 2011, 8: 1154-1164. 10.1002/ppap.201100078.CrossRef
4.
Chiper AS, Chen W, Mejlholm O, Dalgaard P, Stamate E: Atmospheric pressure plasma produced inside a closed package by dielectric barrier discharge in Ar/CO2 for bacterial inactivation of biological samples. Plasma Sources Sci Technol. 2011, 20: 10-CrossRef
5.
Chiang MH, Wu JY, Li YH, Wu S, Chen SH, Chang CL: Inactivation of E. coli and B. subtilis by a parallel-plate dielectric barrier discharge jet. Surf Coat Technol. 2010, 204: 3729-3737. 10.1016/j.surfcoat.2010.04.057.CrossRef
6.
Kogelschatz U, Eliasson B, Walter E: From ozone generator to flat television screens: history and future potential of dielectric barrier discharges. Pure Appl Chem. 1999, 71: 1819-1828. 10.1351/pac199971101819.CrossRef
7.
Kogelschatz U, Hirth M, Eliasson B: Ozone synthesis from oxygen in dielectric barrier discharges. J Phys D: Appl Phy. 1987, 20: 1421-1437. 10.1088/0022-3727/20/11/010.CrossRef
8.
Wagner HE, Brandenburg R, Kozlov KV, Sonnenfeld A, Michel P, Behnke JF: The barrier discharge: basic properties and application to surface treatment. Vacuum. 2003, 71: 417-436. 10.1016/S0042-207X(02)00765-0.CrossRef
9.
Boyd IW, Zhang ZY, Kogelschatz U: Development and applications of UV excimer lamps, Photo-Excited Processes, Diagnostics and Applications. Edited by: Peled A. 2003, The Netherlands: Kluwer Academic, 161-199.
10.
Lomaev MI, Sosnin EA, Tarasenko VF, Shitts DV, Skakun VS, Erofeev MV: Capacitive and barrier discharge excilamps and their applications. Instrum Exp Tech. 2006, 49: 595-746. 10.1134/S0020441206050010.CrossRef
11.
Tarasenko VF: Excilamps as efficient UV-VUV light sources. Pure Appl Chem. 2002, 74: 465-469. 10.1351/pac200274030465.CrossRef
12.
Morimoto Y, Sumitomo T, Yoshioka M, Takemura T: Recent progress on UV lamps for industries. Ind Appl Confer, IAS, IEEE. 2004, 2: 1008-1015.
13.
Oppenlander T, Sosnin E: Mercury free (VUV) and UV excil lamps: lamps of the future. IUVA news. 2005, 7: 16-20.
14.
Eliasson B, Kogelschatz U: Non-equilibrium volume plasma chemical processing. IEEE Trans Plasma Sci. 1991, 19: 1063-1077. 10.1109/27.125031.CrossRef
15.
Pietsch GJ: Peculiarities of dielectric barrier discharges. Contrib Plasma Phys. 2001, 41: 620-628. 10.1002/1521-3986(200111)41:6<620::AID-CTPP620>3.0.CO;2-H.CrossRef
16.
Kogelschatz U: Dielectric-barrier discharges: Their history, discharge physics, and industrial applications. Plasma Chem Plasma Proc. 2003, 23: 1-46. 10.1023/A:1022470901385.CrossRef
17.
Chirokov A, Gutsol A, Fridman A: Atmospheric pressure plasma of dielectric barrier discharges. Pure Appl Chem. 2005, 77: 487-495. 10.1351/pac200577020487.CrossRef
18.
Fridman G, Peddinghaus M, Ayan H, Fridman A, Balasubramanian M, Gutsol A, Brooks A, Friedman G: Blood coagulation and living tissue sterilization by floating-electrode dielectric barrier discharge in air. Plasma Chem Plasma. 2006, 26: 425-442. 10.1007/s11090-006-9024-4.CrossRef
19.
Kalghatgi SU, Fridman G, Fridman A, Friedman G, Clyne AM: 2008 Non-thermal dielectric barrier discharge plasma treatment of endothelial cells. Conf Proc IEEE Eng Med Biol Soc. 2008, 2008: 3578-3581.PubMed
20.
Fridman G, Shereshevsky A, Jost MM, Brooks AD, Fridman A, Gutsol A, Vasilets V, Friedman G: Floating electrode dielectric barrier discharge plasma in air promoting apoptotic behavior in melanoma skin cancer cell lines. Plasma Chem Plasma Process. 2007, 27: 163-176. 10.1007/s11090-007-9048-4.CrossRef
21.
Cooper M, Fridman G, Fridman A, Joshi SG: Biological responses of Bacillus stratosphericus to floating electrode-dielectric barrier discharge plasma treatment. J Appl Microbiol. 2010, 109: 2039-2048. 10.1111/j.1365-2672.2010.04834.x.PubMedCrossRef
22.
Joshi SG, et al: Control of methicillin-resistant Staphylococcus aureus in planktonic form and biofilms: a biocidal efficacy study of nonthermal dielectric-barrier discharge plasma. Am J Infect Control. 2010, 38: 293-301. 10.1016/j.ajic.2009.11.002.PubMedCrossRef
23.
Teschke M, Kedzierski J, Finantu-Dinu EG, Korzec D, Engemann J: High-speed photographs of a dielectric barrier atmospheric pressure plasma jet. IEEE Trans Plasma Sci. 2005, 33: 310-CrossRef
24.
Chen G, Chen S, Zhou M, Feng W, Gu W, Yang S: The preliminary discharging characterization of a novel APGD plume and its application in organic contaminant degradation. Plasma Sources Sci Technol. 2006, 15: 603-10.1088/0963-0252/15/4/002.CrossRef
25.
Kim DB, Rhee JK, Moon SY, Choe W: Study of geometrical and operational parameters controlling the low frequency microjet atmospheric pressure plasma characteristics. Appl Phys Lett. 2006, 89: 061502-10.1063/1.2335956.CrossRef
26.
Schütze A, Jeong JY, Babayan SE, Park J, Selwyn GS, Hicks RF: The atmospheric-pressure plasma jet: a review and comparison to other plasma sources. IEEE Trans Plasma Sci. 1998, 26: 1685-10.1109/27.747887.CrossRef
27.
Herrmann HW, Henins I, Park J, Selwyn GS: Decontamination of chemical and biological warfare (CBW) agents using an atmospheric pressure plasma jet (APPJ). Phys Plasmas. 1999, 6: 2284-10.1063/1.873480.CrossRef
28.
Abramzon N, Joaquin JC, Bray J, Brelles-Marino G: Biofilm destruction by RF high-pressure cold plasma jet. IEEE Trans Plasma Sci. 2006, 34 (4): 1304-1309.CrossRef
29.
Fricke K, Koban I, Tresp H, Jablonowski L, Schröder K, Kramer A, Weltmann K-D, von Woedtke T, Kocher T: Atmospheric pressure plasma: a high-performance tool for the efficient removal of biofilms. PLOS ONE. 2012, 7 (8): e42539-10.1371/journal.pone.0042539. doi:10.1371/journal.pone.0042539PubMedCentralPubMedCrossRef
30.
Niemira BA: Cold plasma reduction of salmonella and escherichia coli O157:H7 on almonds using ambient pressure gases. J Food Sci. 2012, 77 (3): M171-M175. 10.1111/j.1750-3841.2011.02594.x.PubMedCrossRef
31.
Tseng S, Abramzon N, Jackson JO, Lin W-J: Gas discharge plasmas are effective in inactivating Bacillus and Clostridium spores. Appl Microbiol Biotechnol. 2012, 93: 2563-2570. 10.1007/s00253-011-3661-0.PubMedCrossRef
32.
Alkawareek MY, Algwari QT, Gorman SP, Graham WG, O'Connell D, et al: Application of atmospheric pressure nonthermal plasma for the in vitro eradication of bacterial biofilms. FEMS Immunol Med Microbiol. 2012, 65: 381-384. 10.1111/j.1574-695X.2012.00942.x.PubMedCrossRef
33.
Jiang C, Schaudinn C, Jaramillo DE, Webster P, Costerton JW: In vitro antimicrobial effect of a cold plasma jet against Enterococcus faecalis biofilms. ISRN Dentistry. 2012, 2012: 295736-PubMedCentralPubMedCrossRef
34.
Matthes R, Bekeschus S, Bender C, Hübner N-O, Kramer A: Pilot-study on the influence of carrier gas and plasma application (open resp. delimited) modifications on physical plasma and its antimicrobial effect against Pseudomonas aeruginosa and Staphylococcus aureus. GMS Krankenhaushygiene Interdisziplinär. 2012, 7 (1): Doc02-doi:10.3205/dgkh000186PubMedCentralPubMed
35.
Hong YF, Kang JG, Lee HY, Uhm HS, Moon E, Park YH: Sterilization effect of atmospheric plasma on Escherichia coli and Bacillus subtilis endospores. Lett Appl Microbiol. 2009, 48 (1): 33-37. 10.1111/j.1472-765X.2008.02480.x.PubMedCrossRef
36.
Koinuma H, Ohkubo H, Hashimoto T, Inomata K, Shiraishi T, Miyanaga A, Hayashi S: Development and application of a microbeam plasma generator. Appl Phys Lett. 1992, 60 (7): 816-817. 10.1063/1.106527.CrossRef
37.
Inomata K, Ha H, Chaudhary KA, Koinuma H: Open air deposition of SiO2 film from a cold plasma torch of tetramethoxysilane‐H2‐Ar system. Appl Phys Lett. 1994, 64: 46-10.1063/1.110916.CrossRef
38.
Ha H, Inomata K, Koinuma H: Plasma chemical vapor deposition of SiO2 on air-exposed surfaces by cold plasma torch. J Electrochem Soc. 1995, 142 (8): 2726-2730. 10.1149/1.2050082.CrossRef
39.
Inomata K, Koinuma H, Oikawa Y, Shiraishi T: Open air photoresist ashing by a cold plasma torch: catalytic effect of cathode material. Appl Phys Lett. 1995, 66: 2188-10.1063/1.113942.CrossRef
40.
Ha H, Yoshimoto M, Koinuma H, Moon BK, Ishiwara H: Open air plasma chemical vapor deposition of highly dielectric amorphous TiO2 films. Appl Phys Lett. 1996, 68: 2965-10.1063/1.116370.CrossRef
41.
Ha H, Moon BK, Horiuchi T, Inushima T, Ishiwara H, Koinuma H: Structure and electric properties of TiO2 films prepared by cold plasma torch under atmospheric pressure. Mater Sci Eng. 1996, B41 (1): 143-147.CrossRef
42.
Inomata K, Aoki N, Koinuma H: Jpn J Appl Phys. 1994, 33: 197-10.1143/JJAP.33.L197.CrossRef
43.
Lee B, Kusano Y, Kato N, Naito K, Horiuchi T, Koinuma H: Oxygen plasma treatment of rubber surface by the atmospheric pressure cold plasma torch. Jpn J Appl Phys. 1997, 36 (5A): 2888-2891.CrossRef
44.
Stoffels E, Flikweert AJ, Stoffels WW, Kroesen GMW: Plasma needle: a non–destructive atmospheric plasma source for fine surface treatment of (bio) materials. Plasma Sources Sci T. 2002, 4: 383-388.CrossRef
45.
Kieft IE, Laan EPvd, Stoffels E: Electrical and optical characterization of the plasma needle. New J Phys. 2004, 6: 149-CrossRef
46.
Li S-Z, Huang W-T, Zhang J, Wang D: Optical diagnosis of an argon/oxygen needle plasma generated at atmospheric pressure. Appl Phys Lett. 2009, 94: 111501-10.1063/1.3099339.CrossRef
47.
Govil S, Gupta V, Pradhan S: Plasma needle: the future of dentistry. Indian J Basic Appl Med Res. 2012, 1 (2): 143-147.
48.
Jiang C, Gundersen MA, Schaudinn C, Webster P, Jaramillo DE, Sedghizadeh PP, Costerton JW: An atmospheric pressure non-thermal plasma needle for endodontic biofilm disinfection. IEEE Int Confer Plasma Sci - ICOPS. 2011, 1-1. doi:10.1109/PLASMA.2011.5993048
49.
van den Bedem LJM, Sladek REJ, Steinbuch M, Stoffels Adamowicz E: Plasma treatment of S. mutans biofilms cultured in a simulated dental cavity model. 2005, Eindhoven, the Netherlands: XXVIIth ICPIG
50.
Schaudinn C, Jaramillo D, Freire MO, Sedghizadeh PP, Nguyen A, Webster P, Costerton JW, Jiang C: Evaluation of a nonthermal plasma needle to eliminate ex vivo biofilms in root canals of extracted human teeth. Int Endod J. 2013, 46 (10): 1-8.CrossRef
51.
Sladek REJ, Filoche SK, Sissons CH, Stoffels E: Treatment of Streptococcus mutans biofilms with a nonthermal atmospheric plasma. Lett Appl Microbiol. 2007, 45 (3): 318-323. 10.1111/j.1472-765X.2007.02194.x.PubMedCrossRef
52.
Sladek REJ, Baede TA, Stoffels E: Plasma-needle treatment of substrates with respect to wettability and growth of Escherichia coli and Streptococcus mutans. IEEE T Plasma Sci. 2006, 34: 1325-1330.CrossRef
53.
Sladek REJ, Stoffels E: Deactivation of Escherichia coli by the plasma needle. J Phys D-Appl Phys. 2005, 38: 1716-1721. 10.1088/0022-3727/38/11/012.CrossRef
54.
Laroussi M, Lu X: Room temperature atmospheric pressure plasma plume for biomedical applications. Appl Phys Lett. 2005, 87: 113902-10.1063/1.2045549.CrossRef
55.
Laroussi M, Tendero C, Lu X, Alla S, Hynes WL: Inactivation of bacteria by the plasma pencil. Plasma Processes Polym. 2006, 3: 470-473. 10.1002/ppap.200600005.CrossRef
56.
Barekzi N, Laroussi M: Dose-dependent killing of leukemia cells by low-temperature plasma. J Phys D Appl Phys. 45: 422002-doi:10.1088/0022-3727/45/42/422002
57.
Mahasneh A, Darby M, Tolle SL, Hynes W, Laroussi M, Karakas E: Inactivation of Porphyromonas gingivalis by low-temperature atmospheric pressure plasma. Plasma Med. 2011, 1 (3–4): 191-204.CrossRef
58.
Foster JE, Weatherford B, Gillman E, Yee B: Underwater operation of a DBD plasma jet. Plasma Sources Sci T. 2010, 19 (2): 025001-10.1088/0963-0252/19/2/025001.CrossRef
59.
Zhang J, Sun J, Wang D, Wang X: A novel cold plasma jet generated by atmospheric dielectric barrier capillary discharge. Thin Solid Films. 2006, 506: 404-CrossRef
60.
Walsh JL, Shi JJ, Kong MG: Contrasting characteristics of pulsed and sinusoidal cold atmospheric plasma jets. Appl Phys Lett. 2006, 88: 171501-10.1063/1.2198100.CrossRef
61.
Laroussi M: Sterilization of contaminated matter with an atmospheric pressure plasma. IEEE Trans Plasma Sci. 1996, 24: 1188-1191. 10.1109/27.533129.CrossRef
62.
Ermolaeva SA, Sysolyatina EV, Kolkova NI, Bortsov P, Tuhvatulin AI, Vasiliev MM, Mukhachev AY, Petrov OF, Tetsuji S, Naroditsky BS, Morfill GE, Fortov VE, Grigoriev AI, Zigangirova NA, Gintsburg AL: Non-thermal argon plasma is bactericidal for the intracellular bacterial pathogen Chlamydia trachomatis. J Med Microbiol. 2012, 61: 793-799. 10.1099/jmm.0.038117-0.PubMedCrossRef
63.
Klämpfl TG, Isbary G, Shimizu T, Li Y-F, Zimmermann JL, Stolz W, Schlegel J, Morfill GE, Schmidt H-U: Cold atmospheric air plasma sterilization against spores and other microorganisms of clinical interest. Appl Environ Microbiol. 2012, 78 (15): 5077-10.1128/AEM.00583-12.PubMedCentralPubMedCrossRef
64.
Leclaire C, Lecoq E, Orial G, Clement F, Bousta F: Fungal decontamination by cold plasma : an innovating process for wood treatment. 2008, Braga (Portugal): COST Action IE0601 / ESWM - International Conference 5–7 November 2008
65.
Moreau S, Moisan M, Tabrizian M, Barbeau J, Pelletier J, Ricard A, Yahia L: Using the flowing afterglow of a plasma to inactivate Bacillus subtilis spores: Influence of the operating conditions. J Appl Phys. 2000, 88: 1166-1174. 10.1063/1.373792.CrossRef
66.
Richardson JP, Dyer FF, Dobbs FC, Alexeff I, Laroussi M: Year. On the use of the resistive barrier discharge to kill bacteria: Recent results. 27th IEEE International Conference on Plasma Science - ICOPS2000. 2000, New Orleans(USA), 109-109.
67.
Laroussi M, Leipold F: Evaluation of the roles of reactive species, heat, and UV radiation in the inactivation of bacterial cells by air plasmas at atmospheric pressure. Int J Mass Spectrom. 2004, 233: 81-86. 10.1016/j.ijms.2003.11.016.CrossRef
68.
Fridman G, Friedman G, Gutsol A, Shekhter AB, Vasilets VN, Fridman A: Applied plasma medicine. Plasma Processes Polym. 2008, 5: 503-533. 10.1002/ppap.200700154.CrossRef
69.
Joshi SG, Cooper M, Yost A, Paff M, Ercan UK, Fridman G, Friedman G, Fridman A, Brooks AD: Nonthermal dielectric-barrier discharge plasma-induced inactivation involves oxidative dna damage and membrane lipid peroxidation in Escherichia coli. Antimicrob Agents Chemother. 2012, 56 (4): 2028-2036. 10.1128/AAC.05642-11.CrossRef
70.
Kelly-Wintenberg K, Hodge A, Montie TC, Deleanu L, Sherman D, Roth JR, Tsai P, Wadsworth L: Use of a one atmosphere uniform glow discharge plasma to kill a broad spectrum of microorganisms. J Vac Sci Technol A-Vacuum Surfaces and Films. 1999, 17: 1539-1544. 10.1116/1.581849.CrossRef
71.
Mendis DA, Rosenberg M, Azam F: A note on the possible electrostatic disruption of bacteria. IEEE T Plasma Sci. 2000, 28: 1304-1306. 10.1109/27.893321.CrossRef
72.
Laroussi M: Nonthermal decontamination of biological media by atmospheric pressure plasmas: Review, analysis, and prospects. IEEE T Plasma Sci. 2002, 30: 1409-1415. 10.1109/TPS.2002.804220.CrossRef
73.
Fridman G, Brooks AD, Balasubramanian M, Fridman A, Gutsol A, Vasilets VN, Ayan H, Friedman G: Comparison of direct and indirect effects of nonthermal atmospheric-pressure plasma on bacteria. Plasma Processes Polym. 2007, 4: 370-375. 10.1002/ppap.200600217.CrossRef
74.
Stoffels E, Sakiyama Y, Graves DB: Cold atmospheric plasma: charged species and their interactions with cells and tissues. IEEE Trans Plasma Sci. 2008, 36: 1441-1457.CrossRef
75.
Munakata N, Hieda K, Kobayashi K, Ito A, Ito T: Action spectra in ultraviolet wavelengths (150–250 nm) for inactivation and mutagenesis of Bacillus subtilis spores obtained with synchrotron radiation. Photochem Photobiol. 1986, 44: 385-390. 10.1111/j.1751-1097.1986.tb04680.x.PubMedCrossRef
76.
Choi JH, Han I, Baik HK, Lee MH, Han DW, Park JC, Lee IS, Song KM, Lim YS: Analysis of sterilization effect by pulsed dielectric barrier discharge. J Electrostat. 2006, 64: 17-22. 10.1016/j.elstat.2005.04.001.CrossRef
77.
Kelly-Wintenberg K, Montie TC, Brickman C, Roth JR, Carr AK, Sorge K, Wadsworth LC, Tsai PPY: Room temperature sterilization of surfaces and fabrics with a One Atmosphere Uniform Glow Discharge Plasma. J Ind Microbiol Biotechnol. 1998, 20: 69-74. 10.1038/sj.jim.2900482.PubMedCrossRef
78.
Birmingham JG: Mechanisms of bacterial spore deactivation using ambient pressure nonthermal discharges. IEEE T Plasma Sci. 2004, 32: 1526-1531. 10.1109/TPS.2004.832609.CrossRef
79.
Kostov KG, Rocha V, Koga-Ito CY, Matos BM, Algatti MA, Honda RY, Kayama ME, Mota RP: Bacterial sterilization by a dielectric barrier discharge (DBD) in air. Surf Coat Tech. 2010, 204: 2954-2959. 10.1016/j.surfcoat.2010.01.052.CrossRef
80.
Trompeter FJ, Neff WJ, Franken O, Heise M, Neiger M, Liu SH, Pietsch GJ, Saveljew AB: Reduction of Bacillus Subtilis and Aspergillus Niger spores using nonthermal atmospheric gas discharges. IEEE T Plasma Sci. 2002, 30: 1416-1423. 10.1109/TPS.2002.804182.CrossRef
81.
Heise M, Neff W, Franken O, Muranyi P, Wunderlich J: Sterilization of polymer foils with dielectric barrier discharges at atmospheric pressure. Plasmas Polym. 2004, 9: 23-33.CrossRef
82.
Park BJ, Lee DH, Park JC, Lee IS, Lee KY, Hyun SO, Chun MS, Chung KH: Sterilization using a microwave-induced argon plasma system at atmospheric pressure. Phys Plasmas. 2003, 10: 4539-4544. 10.1063/1.1613655.CrossRef
83.
Lee KY, Park BJ, Lee DH, Lee IS, Hyun SO, Chung KH, Park JC: Sterilization of Escherichia coli and MRSA using microwave-induced argon plasma at atmospheric pressure. Surf Coat Tech. 2005, 193: 35-38. 10.1016/j.surfcoat.2004.07.034.CrossRef
84.
Boudam MK, Moisan M, Saoudi B, Popovici C, Gherardi N, Massines F: Bacterial spore inactivation by atmospheric-pressure plasmas in the presence or absence of UV photons as obtained with the same gas mixture. J Phys D Appl Phys. 2006, 39: 3494-10.1088/0022-3727/39/16/S07.CrossRef
85.
Pennies E: A mouth full of microbes. Science. 2005, 307: 1899-1901. 10.1126/science.307.5717.1899.CrossRef
86.
Gibbons RJ, Van Houte J: Dental caries. Annu Rev Med. 1975, 26: 121-136. 10.1146/annurev.me.26.020175.001005.PubMedCrossRef
87.
Mosci F, Perito S, Bassa S, Capuano A, Marconi PF: The role of Streptococcus mutans in human caries. Minerva Stomatol. 1990, 39 (5): 413-429.PubMed
88.
Yip HK, Samaranayake LP: Caries removal techniques and instrumentation: a review. Clin Oral Investig. 1998, 2 (4): 148-154. 10.1007/s007840050062.PubMedCrossRef
89.
Banerjee A, Watson TF, Kidd EA: Dentine caries excavation: a review of current clinical techniques. Br Dent J. 2000, 188 (9): 476-482.PubMed
90.
Baysan A, Whiley RA, Lynch E: Antimicrobial effect of a novel ozone– generating device on micro–organisms associated with primary root carious lesions in vitro. Caries Res. 2003, 34 (6): 498-501.CrossRef
91.
Nagayoshi M, Fukuizumi T, Kitamura C, Yano J, Terashita M, Nishihara T: Efficacy of ozone on survival and permeability of oral microorganisms. Oral Microbiol Immun. 2004, 19 (4): 240-246. 10.1111/j.1399-302X.2004.00146.x.CrossRef
92.
Hems RS, Gulabivala K, Ng YL, Ready D, Spratt DA: An in vitro evaluation of the ability of ozone to kill a strain of Enterococcus faecalis. Int Endod J. 2005, 38: 22-29. 10.1111/j.1365-2591.2004.00891.x.PubMedCrossRef
93.
Malmstrom HS, McCormack SM, Fried D, Featherstone JDB: Effect of CO2 laser on pulpal temperature and surface morphology: an in vitro study. J Dent. 2001, 29 (8): 521-529. 10.1016/S0300-5712(01)00028-8.PubMedCrossRef
94.
Yoon G, Zabaznov M, Tsvetkov B, Kim S, Shcherbakov A: A compact 1.06/1.32/2.94 mm pulsed laser for dentistry. Opt Laser Technol. 2002, 34 (3): 213-217. 10.1016/S0030-3992(01)00113-X.CrossRef
95.
Holmes J: Clinical reversal of root caries using ozone, double–blind, randomized, controlled 18–month trial. Gerontology. 2003, 20 (2): 106-114.
96.
Marsh PD: Dental plaque as a biofilm and a microbial community – implications for health and disease. BMC Oral Health. 2006, 6 (Suppl 1): S14-10.1186/1472-6831-6-S1-S14.PubMedCentralPubMedCrossRef
97.
Goree J, Liu B, Drake D, Stoffels E: Killing of S-mutans bacteria using a plasma needle at atmospheric pressure. IEEE Transactions on Plasma Science. 2006, 34: 1317-1324.CrossRef
98.
Morris AD, McCombs GB, Akan T, Hynes W, Laroussi M, Tolle SL: Cold Plasma Technology: Bactericidal Effects on Geobacillus Stearothermophilus and Bacillus Cereus Microorganisms. J Dent Hygiene. 2009, 83 (2): 55-61.
99.
Bo Y, Jierong C, Qingsong Y, Hao L, Mengshi L, Azlin M, Liang H, Yong W: Oral bacteria deactivation using a low-temperature atmospheric argon plasma brush. J Dent. 2011, 39: 48-56. 10.1016/j.jdent.2010.10.002.CrossRef
100.
Sung Kil K, Myeong Yeol C, Il Gyo K, Kim PY, Yoonsun K, Gon Jun K, Mohamed A-AH, Collins GJ, Jae Koo L: Reactive hydroxyl radical-driven oral bacterial inactivation by radio frequency atmospheric plasma. Appl. Phys. Lett. 2011, 98 (14): 143702-143702–3. 10.1063/1.3574639.CrossRef
101.
Jiang CQ, Chen MT, Gorur A, Schaudinn C, Jaramillo DE, Costerton JW, Sedghizadeh PP, Vernier PT, Gundersen MA: Nanosecond Pulsed Plasma Dental Probe. Plasma Processes and Polymers. 2009, 6: 479-483. 10.1002/ppap.200800133.CrossRef
102.
Rupf S, Lehmann A, Hannig M, Schäfer B, Schubert A, Feldmann U, Schindler A: Killing of adherent oral microbes by a non-thermal atmospheric plasma jet. J Med Microbiol. 2010, 59: 206-212. 10.1099/jmm.0.013714-0.PubMedCrossRef
103.
Lu XP, Cao YG, Yang P, Xiong Q, Xiong ZL, Xian YB, Pan Y: An RC Plasma Device for Sterilization of Root Canal of Teeth. IEEE Transactions on Plasma Science. 2009, 37: 668-673.CrossRef
104.
Li Y: Tooth bleaching using peroxide-containing agents: current status of safety issues. Compend Contin Educ Dent. 1998, 19 (8): 783-786. 788, 790, passim; quiz 796PubMed
105.
Kawamoto K, Tsujimoto Y: Effects of the hydroxyl radical and hydrogen peroxide on tooth bleaching. J Endod. 2004, 30: 45-50. 10.1097/00004770-200401000-00010.PubMedCrossRef
106.
Lee HW, Kim GJ, Kim JM, Park JK, Lee JK, Kim GC: Tooth bleaching with nonthermal atmospheric pressure plasma. J. Endod. 2009, 35 (4): 587-591. 10.1016/j.joen.2009.01.008.PubMedCrossRef
107.
Lee HW, Nam SH, Mohamed AH, Kim GC, Lee JK: Atmospheric Pressure Plasma Jet Composed of Three Electrodes: Application to Tooth Bleaching. Plasma Process. Polym. 2010, 7: 274-280. 10.1002/ppap.200900083.CrossRef
108.
Sun P, Pan J, Tian Y, Bai N, Wu H, Wang L, Yu C, Wei S, Zhang J, Zhu W, Fang J: Tooth-whitening with hydrogen peroxide assisted by a direct current, cold, atmospheric-pressure air plasma microjet. IEEE Trans. Plasma Sci. 2010, 38 (8): 1892-1896.CrossRef
109.
Jie P, Peng S, Ye T, Haixia Z, Haiyan W, Na B, Fuxiang L, Weidong Z, Jue Z, Becker KH, Jing F: A Novel Method of Tooth Whitening Using Cold Plasma Microjet Driven by Direct Current in Atmospheric-Pressure Air. IEEE TRANSACTIONS ON PLASMA SCIENCE. 2010, 38 (NO. 11): 3143-3151.CrossRef
110.
Park JK, Nam SH, Kwon HC, Mohamed AAH, Lee JK, Kim GC: Feasibility of non thermal atmospheric pressure plasma for intracoronal bleaching. Int. Endod. J. 2011, 44: 170-10.1111/j.1365-2591.2010.01828.x.PubMedCrossRef
111.
Seoul Hee NAM, Hyun Woo LEE, Soo Hyun CHO, Jae Koo LEE, Young Chan JEON, Gyoo Cheon KIM: High-efficiency tooth bleaching using nonthermal atmospheric pressure plasma with low concentration of hydrogen peroxide. J Appl Oral Sci. 2013, 21 (3): 265-270.
112.
Claiborne D, McCombs G, Lemaster M, Akman MA, Laroussi M: Low-temperature atmospheric pressure plasma enhanced tooth whitening: the next-generation technology. Int J Dent Hygiene. 2013, doi:10.1111/idh.12031
113.
Rupf S, Idlibi AN, Umanskaya N, Hannig M, Nothdurft F, Lehmann A, Schindler A, Lv M, Spitzer W: Disinfection and removal of biofilms on microstructured titanium by cold atmospheric plasma. Deutscher Ärzte-Verlag. 2012, 28 (2): 126-137.
114.
Koban I, Holtfreter B, Hu¨bner N-O, Matthes R, Sietmann R, Kindel E, Weltmann K-D, Welk A, Kramer A, Kocher T: Antimicrobial efficacy of non-thermal plasma in comparison to chlorhexidine against dental biofilms on titanium discs in vitro – proof of principle experiment. J Clin Periodontol. 2011, 38: 956-965. 10.1111/j.1600-051X.2011.01740.x.PubMedCrossRef
115.
Su-Jin S, Jung-Bo H, Mi-Jung Y, Chang BMW, Chang-Mo J, Young-Chan J: Sterilization effect of atmospheric pressure non-thermal air plasma on dental instruments. J Adv Prosthodont. 2013, 5: 2-8. 10.4047/jap.2013.5.1.2.CrossRef
116.
Ahmad Nour I, Fuad A-M, Matthias H, Antje L, Andre R, Axel S, Holger J, Stefan R: Destruction of oral biofilms formed in situ on machined titanium (Ti) surfaces by cold atmospheric plasma. Biofouling. 2013, 29 (No. 4): 369-379. 10.1080/08927014.2013.775255.CrossRef
117.
Andy Charles R, Hao L, Qingsong Y, Changqi X, Xiaomei Y, Liang H, Yong W: Dentin surface treatment using a non-thermal argon plasma brush for interfacial bonding improvement in composite restoration. Eur J Oral Sci. 2010, 118 (5): 510-516. 10.1111/j.1600-0722.2010.00761.x.CrossRef
118.
Yavirach P, Chaijareenont P, Boonyawan D, Pattamapun K, Tunma S, Takahashi H, Arksornnukit M: Effects of plasma treatment on the shear bond strength between fiber reinforced composite posts and resin composite for core build-up. Dental Materials Journal. 2009, 28 (6): 686-692. 10.4012/dmj.28.686.PubMedCrossRef
119.
Stoffels E: Plasma needle: Treatment of living cells and tissues, in Proc. 2003, San Francisco, CA: Gaseous Electron. Conf, 16-
120.
Yonson S, Coulombe S, Leveille V, Leask R: Cell treatment and surface functionalization using a miniature atmospheric pressure glow discharge plasma torch. J.Phys. D, Appl. Phys. 2006, 39 (16): 3508-3513. 10.1088/0022-3727/39/16/S08.CrossRef
121.
Shashurin A, Keidar M, Bronnikov S, Jurjus RA, Stepp M: Living tissue under treatment of cold atmospheric jet. Appl. Phys. Lett. 2008, 93 (no. 18): 181-501.CrossRef
122.
Kieft IE, Kurdi M, Stoffels E: Reattachment and apoptosis after plasma-needle treatment of cultured cells. IEEE Trans. Plasma Sci. 2006, 34 (4): 1331-1336.CrossRef
123.
Kieft IE, Darios D, Roks AJM, Stoffels E: Plasma treatment of mammalian vascular cells: a quantitative description. IEEE Trans Plasma Sci. 2005, 33: 771-5.CrossRef
124.
Olga V, Mary Ann S, Michael K: ntegrin activation by a cold atmospheric plasma jet. New Journal of Physics. 2012, 14 (16pp): 053019-
125.
Lehnert BE, Iyer R: Exposure to low-level chemicals and ionizing radiation: reactive oxygen species and cellular pathways. Hum Exp Toxicol. 2002, 21: 65-9. 10.1191/0960327102ht212oa.PubMedCrossRef
126.
Sensenig R, Kalghatgi S, Cerchar E, et al: Non-thermal plasma induces apoptosis in melanoma cells via production of intracellular reactive oxygen species. Ann Biomed Eng. 2011, 39: 674-87. 10.1007/s10439-010-0197-x.PubMedCentralPubMedCrossRef
127.
Sun Ja K, Chung TH, Bae SH, Leem SH: Induction of apoptosis in human breast cancer cells by a pulsed atmospheric pressure plasma jet. Appl. Phys. Lett. 2010, 97: 023702-10.1063/1.3462293.CrossRef
128.
Thiyagarajan M, Waldbeser L, Whitmill A: THP-1 leukemia cancer treatment using a portable plasma device. Stud Health Technol Inform. 2012, 173: 515-7.PubMed
129.
Lars Ivo P, Katja E, Jan H, Friderike D, Lars N, Stephan D, Frank-Ulrich W, Matthias E, Nils Olaf H, Cristin G, Claus Dieter H, Axel K, René B, Klaus-Dieter W, Onur P, Claudia B, von Wolfram B: Tissue Tolerable Plasma (TTP) induces apoptosis in pancreatic cancer cells in vitro and in vivo. Partecke et al. BMC Cancer. 2012, 12: 473-10.1186/1471-2407-12-473.CrossRef
130.
Walk RM, Snyder JA, Srinivasan P, Kirsch J, Diaz SO, Blanco FC, Shashurin A, Keidar M, Sandler AD: Cold atmospheric plasma for the ablative treatment of neuroblastoma. J Pediatr Surg. 2013, 48: 67-73. 10.1016/j.jpedsurg.2012.10.020.PubMedCrossRef
131.
Nagendra K, Kaushik , Yong Hee K, Yong Gyu H, Eun Ha C: Effect of jet plasma on T98G human brain cancer cells. Current Applied Physics. 2012
132.
Köritzer J, Boxhammer V, Schäfer A, Shimizu T, Klämpfl TG, Li Y-F, Welz C, Schwenk-Zieger S, Morfill GE, Zimmermann JL, Schlegel J: Restoration of Sensitivity in Chemo — Resistant Glioma Cells by Cold Atmospheric Plasma. PLoS ONE. 2013, 8 (5): e64498-10.1371/journal.pone.0064498.PubMedCentralPubMedCrossRef
133.
Barekzi N, Laroussi M: Dose-dependent killing of leukemia cells by low-temperature plasma. J. Phys. D: Appl. Phys. 2012, 45: 6pp-CrossRef
134.
Chul-Ho K, Seyeoul K, Jae Hoon B, Keunho L, Seung Ik J, Rack PD, Seung Joon B: Effects of atmospheric nonthermal plasma on invasion of colorectal cancer cells. APPLIED PHYSICS LETTERS. 2010, 96: 243701-10.1063/1.3449575.CrossRef
135.
Arndt S, Wacker E, Li Y-F, Shimizu T, Thomas HM, Morfill GE, Karrer S, Zimmermann JL, Bosserhoff A-K: Cold atmospheric plasma, a new strategy to induce senescence in melanoma cells. Experimental Dermatology. 2013, 22: 284-289. 10.1111/exd.12127.PubMedCrossRef
136.
Kim CH, Bahn JH, Lee SH, et al: Induction of cell growth arrest by atmospheric non thermal plasma in colorectal cancer cells. J Biotechnol. 2010, 150 (4): 530-538. 10.1016/j.jbiotec.2010.10.003.PubMedCrossRef
137.
Kim JY, Wei Y, Li J, et al: Single-cell-level microplasma cancer therapy. Small. 2011, 7: 2291-5. 10.1002/smll.201100456.PubMedCrossRef
138.
Vandamme M, Robert E, Pesnel S, et al: Antitumor effect of plasma treatment on U87 glioma xenografts: preliminary results. Plasma Processes Polym. 2010, 7: 264-73. 10.1002/ppap.200900080.CrossRef
139.
Keidar M, Walk R, Shashurin A, Srinivasan P, Sandler A, Dasgupta S, Ravi R, Guerrero-Preston R, Trink B: Cold plasma selectivity and the possibility of a paradigm shift in cancer therapy. Br J Cancer. 2011, 105: 1295-1301. 10.1038/bjc.2011.386.PubMedCentralPubMedCrossRef
140.
Kim GC, Kim GJ, Park S, Jeon S, Seo H, Iza F, Lee J: Air plasma coupled with antibody-conjugated nanoparticles: a new weapon against cancer. J. Phys. D: Appl. Phys. 2009, 42 (No 3): 032005-10.1088/0022-3727/42/3/032005. 5ppCrossRef
141.
Gan Young P, Myoung Soo K, June Ho B, Kyong Tai K, Gyoo Cheon K, Jae Koo L: Biomedical Applications of Low Temperature Atmospheric Pressure Plasmas to Cancerous Cell Treatment and Tooth Bleaching. Jpn. J. Appl. Phys. 2011, 50: 7-08JF01
142.
143.
Jae Young K, John B, Paul F, Thomas H, Yanzhang W, Jinhua L, Sung-O K: Apoptosis of lung carcinoma cells induced by a flexible optical fiber-based cold microplasma. Biosensors and Bioelectronics. 2011, 28: 333-338. 10.1016/j.bios.2011.07.039.CrossRef
144.
Jae Young K, John B, Paul F, Thomas H, Yanzhang W, Jinhua L, Sung-O K: Single Cellular and Endoscopic Micro-plasma Cancer Therapy, Small. 2011, 7 (16): 2290-
145.
Bomi G, Mina K, Dan Bee K, Daeyeon K, Hyeonyu K, et al: Differential responses of human liver cancer and normal cells to atmospheric pressure plasma. APPLIED PHYSICS LETTERS. 2011, 99: 063701-10.1063/1.3622631.CrossRef
146.
Georgescu N, Lupu AR: Tumoral and normal cells treatment with high-voltage pulsed cold atmospheric plasma jets. Plasma Science, IEEE Trans. 2010, 38: 1949-55.CrossRef
147.
Panngom K, Baik KY, Nam MK, Han JH, Rhim H, Choi EH: Preferential killing of human lung cancer cell lines with mitochondrial dysfunction by nonthermal dielectric barrier discharge plasma. Cell Death Dis. 2013, 4 (5): e642-10.1038/cddis.2013.168.PubMedCentralPubMedCrossRef
148.
Tuhvatulin AI, Sysolyatina EV, Scheblyakov DV, DYu L, Vasiliev MM, Yurova MA, Danilova MA, Petrov OF, Naroditsky BS, Morfill GE, Grigoriev AI, Fortov VE, Gintsburg AL, Ermolaeva SA: Non-thermal Plasma Causes p53-Dependent Apoptosis in Human Colon Carcinoma Cells. Acta Naturae. 2012, 4 (3): 82-87.PubMedCentralPubMed
149.
Yan X, Zou F, Zhao S, Lu X, He G, Xiong Z, Xiong Q, Zhao Q, Deng P, Hunag J, Yang G: On the mechanism of plasma inducing cell apoptosis. IEEE Trans Plasma Sci. 2010
150.
Vandamme M, Robert E, Lerondel S, Sarron V, Ries D, Dozias S, Sobilo J, Gosset D, Kieda C, Legrain B, Pape J-MPAL: ROS implication in a new antitumor strategy based on non-thermal plasma. Int. J. Cancer. 2012, 130: 2185-2194. 10.1002/ijc.26252.PubMedCrossRef
151.
Hak Jun A, Kang Il K, Geunyoung K, Eunpyo M, Sang Sik Y, Jong-Soo L: Atmospheric-Pressure Plasma Jet Induces Apoptosis Involving Mitochondria via Generation of Free Radicals. PLoS ONE. 2011, 6 (11): e28154-10.1371/journal.pone.0028154. doi:10.1371/journal.pone.0028154CrossRef
152.
Xu Y, Zilan X, Fei Z, Shasha Z, Xinpei L, Guangxiao Y, Guangyuan H, Ostrikov K (K): Plasma-Induced Death of HepG2 Cancer Cells: Intracellular Effects of Reactive Species, Plasma Process. Polym. 2012, 9: 59-66.
153.
Rodríguez-Lozano FJ, Insausti CL, Iniesta F, Blanquer M, Ramírez MD, Meseguer L, Meseguer-Henarejos AB, Marín N, Martínez S, Moraleda JM: Mesenchymal dental stem cells in regenerative dentistry. Med Oral Patol Oral Cir Bucal. 2012, 17 (6): e1062-e1067.PubMedCentralPubMedCrossRef
Metadata
Title
Cold Atmospheric Plasma: methods of production and application in dentistry and oncology
Authors
Clotilde Hoffmann
Carlos Berganza
John Zhang
Publication date
01-12-2013
Publisher
BioMed Central
Published in
Medical Gas Research / Issue 1/2013
Electronic ISSN: 2045-9912
DOI
https://doi.org/10.1186/2045-9912-3-21

Other articles of this Issue 1/2013

Medical Gas Research 1/2013 Go to the issue

Review

Volatile anesthetics-induced neuroinflammatory and anti-inflammatory responses

Review

Hydrogen sulfide as a vasculoprotective factor

Research

Hydrogen water intake via tube-feeding for patients with pressure ulcer and its reconstructive effects on normal human skin cells in vitro

Review

The role of helium gas in medicine

Review

The immunomodulatory role of carbon monoxide during transplantation

Review

XENON in medical area: emphasis on neuroprotection in hypoxia and anesthesia

ACC 2024 Congress Coverage

Heart Failure Video

Year in Review: Heart failure and cardiomyopathies

Watch now

Watch this official video from ACC.24. Dr. Biykem Bozkurt discuss last year's major advances in heart failure and cardiomyopathies.

Semaglutide benefits people with type 2 diabetes and obesity-related heart failure

16-04-2024 Type 2 Diabetes News

Incentivised to exercise

11-04-2024 Lifestyle Modifications News

New intervention for STEMI-related cardiogenic shock

10-04-2024 Myocardial Infarction News

» View more highlights on the ACC 2024 congress hub page

Image Credits