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Open Access 01-12-2013 | Review

Treatment of hepatitis C virus infection in the future

Authors: Tatsuo Kanda, Osamu Yokosuka, Masao Omata

Published in: Clinical and Translational Medicine | Issue 1/2013

Abstract

Two direct-acting antivirals (DAAs) against hepatitis C virus (HCV): telaprevir and boceprevir, are now available in combination with peginterferon plus ribavirin for the treatment of chronic hepatitis C infection. Although these drugs are potent inhibitors of HCV replication, they occasionally result in severe adverse events. In the present clinical trials, in their stead, several second-generation DAAs are being investigated. Most of them are being viewed with high expectations, but they also require the combination with peginterferon plus ribavirin. In the near future, we might be using all-oral DAAs and interferon-free regimens for the treatment of HCV-infected patients, and these would be potent inhibitors of HCV and have less adverse events.

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Title: Treatment of hepatitis C virus infection in the future
Authors: Tatsuo Kanda
Osamu Yokosuka
Masao Omata
Publication date: 01-12-2013
Publisher: Springer Berlin Heidelberg
Published in: Clinical and Translational Medicine / Issue 1/2013
Electronic ISSN: 2001-1326
DOI: https://doi.org/10.1186/2001-1326-2-9

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Treatment of hepatitis C virus infection in the future

Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

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