Published in:
Open Access
01-12-2010 | Poster presentation
Pharmacokinetics of plasma lopinavir/ritonavir following the administration of 400/100, 200/150, and 200/50 mg twice daily in HIV-negative volunteers
Authors:
AGA Jackson, A Hill, LJ Else, DJ Back, R Morley, R Puls, J Amin, E Lin, M Boffito
Published in:
Journal of the International AIDS Society
|
Special Issue 4/2010
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Excerpt
Development and post-marketing data suggest that some licensed ARV doses could be reduced. We assessed the pharmacokinetics (PK) of lopinavir/ritonavir (LPV/r) following the administration of 3 different doses to HIV negative volunteers as a preliminary to the design of clinical trials to examine the safety and efficacy of novel dose regimens in HIV positive subjects. …