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Journal of the International AIDS Society
Published in: Journal of the International AIDS Society 4/2010

Open Access 01-12-2010 | Poster presentation

High levels of polymorphisms related to raltegravir resistance among raltegravir-naïve individuals in Brazil

Authors: N Mantovani Pena, R Gonçalves Azevedo, D Funayama Castro, R Sobhie Diaz, S Vasconcelos Komninakis

Published in: Journal of the International AIDS Society | Special Issue 4/2010

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Excerpt

Raltegravir (RAL) is an HIV-1 integrase strand-transfer inhibitor that has exhibited substantial efficacy and a favorable safety profile in HIV-1 infected patients. The goal of this study was to explore the presence of natural polymorphisms and primary mutations related to RAL resistance among HIV-1 patients failing to multiple antiretroviral agents. …
Literature
1.
Low , et al: Antimicrobial Agents and Chemotherapy. 2009, 53 (10): 4275-4282. Oct. 2009
Metadata
Title
High levels of polymorphisms related to raltegravir resistance among raltegravir-naïve individuals in Brazil
Authors
N Mantovani Pena
R Gonçalves Azevedo
D Funayama Castro
R Sobhie Diaz
S Vasconcelos Komninakis
Publication date
01-12-2010
Publisher
BioMed Central
DOI
https://doi.org/10.1186/1758-2652-13-S4-P135

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