Published in:
Open Access
01-12-2010 | Poster presentation
Analysis of BENCHMRK 1 & 2 using PhenoSense® assay for darunavir (DRV/r) resistance and exploration of functional monotherapy with RAL vs DRV
Authors:
J Rockstroh, J Eron, D Cooper, R Steigbigel, BY Nguyen, X Xu, H Wan, A Rodgers, M Miller, R Leavitt, P Sklar, H Teppler
Published in:
Journal of the International AIDS Society
|
Special Issue 4/2010
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Excerpt
Previous analyses of the 2 BENCHMRK studies of raltegravir (RAL) vs placebo (Pbo) plus optimized background therapy (OBT) in treatment-experienced HIV-infected patients (pts) by PSS as contributed by OBT used assumptions of susceptibility to DRV/r based on prior use, since commercial phenotyping was not available. Re-analysis is now performed using newly available DRV/r phenotype data. …