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Published in: Journal of the International AIDS Society 3/2010

Open Access 01-12-2010 | Oral presentation

CD4+ T cell reconstitution, T cell activation, and memory T cell subset composition in blood and gut of HIV-negative and ART-suppressed HIV-positive patients: implications for HIV persistence in the gut

Authors: S Yukl, E Sinclair, L Epling, Q Li, A Shergill, K McQuaid, L Duan, B Hare, H Lampiris, A Haase, D Havlir, J Wong

Published in: Journal of the International AIDS Society | Special Issue 3/2010

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Excerpt

HIV DNA and RNA levels in the gut exceed those in the blood up to 10-fold. The ileum and rectum differ in HIV levels and responses to intensification, suggesting that mechanisms of persistence may vary between sites. HIV persistence could be impacted by T cell activation, absolute CD4 levels, or composition of memory T cell subsets. …
Metadata
Title
CD4+ T cell reconstitution, T cell activation, and memory T cell subset composition in blood and gut of HIV-negative and ART-suppressed HIV-positive patients: implications for HIV persistence in the gut
Authors
S Yukl
E Sinclair
L Epling
Q Li
A Shergill
K McQuaid
L Duan
B Hare
H Lampiris
A Haase
D Havlir
J Wong
Publication date
01-12-2010
Publisher
BioMed Central
DOI
https://doi.org/10.1186/1758-2652-13-S3-O1

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