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Open Access 01-12-2010 | Case Report

Diagnosis and phylogenetic analysis of Orf virus from goats in China: a case report

Authors: Keshan Zhang, Zhongxin Lu, Youjun Shang, Haixue Zheng, Ye Jin, Jijun He, Xiangtao Liu

Published in: Virology Journal | Issue 1/2010

Abstract

Background

Orf virus (ORFV) is the etiological agent of contagious pustular dermatitis and is the prototype of the genus Parapoxvirus (PPV). It causes a severe exanthematous dermatitis that afflicts domestic and wild small ruminants.

Case presentation

In the present study, an outbreak of proliferative dermatitis in farmed goats. The presence of ORFV in tissue scrapings from the lips was confirmed by B2L gene polymerase chain reaction (PCR) amplification. The molecular characterization of the ORFV was performed using PCR amplification, DNA sequencing and phylogenetic analysis of the B2L gene.

Conclusion

The results of this investigation indicated that the outbreak was caused by infection with an ORFV that was closely related genetically to Nantou (DQ934351), which was isolated from the Tai wan province of China and Hoping (EU935106), which originated from South Korea in 2008. This is the first report of the phylogenetic analysis of ORFV from goats in China.

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Title: Diagnosis and phylogenetic analysis of Orf virus from goats in China: a case report
Authors: Keshan Zhang
Zhongxin Lu
Youjun Shang
Haixue Zheng
Ye Jin
Jijun He
Xiangtao Liu
Publication date: 01-12-2010
Publisher: BioMed Central
Published in: Virology Journal / Issue 1/2010
Electronic ISSN: 1743-422X
DOI: https://doi.org/10.1186/1743-422X-7-78

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Conclusion

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