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Published in: Virology Journal 1/2009

Open Access 01-12-2009 | Short report

Analysis of the coding potential of the partially overlapping 3' ORF in segment 5 of the plant fijiviruses

Authors: Andrew E Firth, John F Atkins

Published in: Virology Journal | Issue 1/2009

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Abstract

The plant-infecting members of the genus Fijivirus (family Reoviridae) have linear dsRNA genomes divided into 10 segments, two of which contain two substantial and non-overlapping ORFs, while the remaining eight are apparently monocistronic. However, one of these – namely segment 5 – contains a second long ORF (~200+ codons) that overlaps the 3' end of the major ORF (~920–940 codons) in the +1 reading frame. In this report, we use bioinformatic techniques to analyze the pattern of base variations across an alignment of fijivirus segment 5 sequences, and show that this 3' ORF has a strong coding signature. Possible translation mechanisms for this unusually positioned ORF are discussed.
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Metadata
Title
Analysis of the coding potential of the partially overlapping 3' ORF in segment 5 of the plant fijiviruses
Authors
Andrew E Firth
John F Atkins
Publication date
01-12-2009
Publisher
BioMed Central
Published in
Virology Journal / Issue 1/2009
Electronic ISSN: 1743-422X
DOI
https://doi.org/10.1186/1743-422X-6-32

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